Ukudla kweChordoma!

Isingeniso

Ukudla kweChordoma kufanele kube okomuntu siqu kumuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukushintsha kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Chordoma wuhlobo olungavamile lomdlavuza olukhula emathanjeni, oluvame ukwenzeka ku-sacrum noma ku-tailbone (coccyx). Uhlaka lwe-Pathology ludlala indima ebalulekile ekuqondeni izici ze-chordoma kanye nokuqondisa ukuxilongwa okunembile. Amasu e-Radiology, okuhlanganisa ukuskena kwe-MRI, abalulekile ekuboneni ngeso lengqondo nasekuhloleni izimila ze-chordoma. Izinhlangano ezifana neChordoma Foundation zinikeza ukusekelwa okubalulekile nezinsiza ezigulini futhi zikhuthaze ucwaningo ngalo mdlavuza ongavamile. Izimpawu ze-chordoma zingahluka kodwa zingabandakanya ubuhlungu, ukuqina, kanye nezimpawu ze-neurological endaweni ethintekile njenge-tailbone. Izinga lokusinda kwe-chordoma lincike ezicini ezihlukahlukene, kuhlanganise nesiteji kanye nezinga lesimila. Ukubhala ngekhodi okunembile kusetshenziswa uhlelo lokuhlukanisa i-ICD-10 kuqinisekisa imibhalo efanele ye-chordoma kumarekhodi ezokwelapha. Nakuba i-chordoma ivame ukuhlotshaniswa nabantu, ingenzeka nasezilwaneni ezifana nama-ferrets. Ukuqonda incazelo nezici ze-chordoma kusiza ekuboneni nasekulawuleni lo mdlavuza oyinselele. I-Chordoma ingathinta nezinye izindawo zomzimba, njenge-clivus. Ukwelashwa kwe-chordoma kuhilela indlela ehlukahlukene, okuhlanganisa ukuhlinzwa, ukwelapha ngemisebe, kanye nokwelashwa ngamakhemikhali. Imihlahlandlela yokwelashwa kanye nokuhlolwa komtholampilo kunomthelela ekuthuthukisweni kokuphathwa kwe-chordoma. I-Chemotherapy ingasetshenziswa ezimeni lapho isimila singasahleki noma simetastasized. Ukuxilongwa kusenesikhathi nokunembile kubalulekile ukuze kusetshenziswe amasu afanele okwelapha e-chordoma. Sekukonke, ucwaningo oluqhubekayo kanye nemithi yokwelapha emisha iqhutshwa ngenkuthalo ukuze kuthuthukiswe imiphumela kanye nekhwalithi yokuphila yabantu abathintwe yi-chordoma.

Ku-Chordoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu engozini yomdlavuza uwukuthi - kumdlavuza onjenge-Chordoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe esitshalweni ingabe kwanele umdlavuza njengeChordoma?

Isibonelo, ingabe kunendaba ukuthi imifino ye-Globe Artichoke idliwa kakhulu uma iqhathaniswa ne-Cardoon? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneRabbiteye Blueberry? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-Brazil Nut kanye nama-pulses afana ne-Alfalfa phezu kweLentils. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukubona kanjani ukudla okunconyelwe i-Chordoma futhi ingabe impendulo efanayo kuwo wonke umuntu onokuxilongwa okufanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba yeChordoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Pummelo iqukethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol. Futhi i-Rabbiteye Blueberry iqukethe izithako ezisebenzayo i-Quercetin, i-Linalool, i-P-coumaric Acid, i-Geraniol, i-Eugenol futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa yiChordoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kweChordoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Chordoma?

Ukondleka komuntu siqu komdlavuza njengeChordoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Chordoma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njengeChordoma

Wonke ama-cancer afana ne-Chordoma angabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zesiginesha ze-Chordoma. Izindlela ze-Biochemical ezifana ne-Cell Cycle, i-Focal Adhesion, i-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics iyingxenye yencazelo yesiginesha ye-Chordoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo e-Chordoma zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla kanye nezithako zokudla kuyanconywa eChordoma lapho uthatha ukwelashwa komdlavuza I-radiation, futhi okunye ukudla nezithako ezingeziwe akunconyiwe.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-DNMT3A, GRM5, PIK3CA, TERT kanye ne-CDKN2A yizakhi zofuzo ezikleliswe phezulu zeChordoma. I-DNMT3A ibikwa ku-12.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-GRM5 ibikwa ku-8.0%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esukela kweyi-10 kuye kwengama-85. Amaphesenti angama-58.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Biology ye-Chordoma kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zeChordoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha Imifino GLOBE ARTICHOKE noma CARDOON?

I-Vegetable Globe Artichoke iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Luteolin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana Nokulungisa kabusha i-Extracellular Matrix, i-Cell Cycle, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Globe Artichoke iyanconywa nge-Chordoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation. Lokhu kungenxa yokuthi i-Globe Artichoke iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela woMsebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Cardoon yemifino yi-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana nokulungisa i-DNA kanye ne-Heat Stress Response nezinye. I-Cardoon ayinconyelwe i-Chordoma uma ukwelashwa komdlavuza okuqhubekayo kuyiRadiation ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-ARTICHOKE YE-VEGETABLE GLOBE INCONYISWA NGAPHEZU KWE-CARDOON NGE-Chordoma KANYE NOKWELASHWA kwemisebe.

Khetha isithelo i-RABITEYE BLUEBERRY noma i-PUMMELO?

I-Fruit Rabbiteye Blueberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Linalool, i-P-coumaric Acid, i-Geraniol, i-Eugenol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics kanye ne-MYC Signaling nezinye. I-Rabbiteye Blueberry iyanconywa ngeChordoma lapho ukwelashwa komdlavuza okuqhubekayo kuyiRadiation. Lokhu kungenxa yokuthi i-Rabbiteye Blueberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela Wemisebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Quercetin, i-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana nokulungisa i-DNA kanye ne-Heat Stress Response nezinye. I-Pummelo ayinconyelwe i-Chordoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ISITHELO I-RABITEYE BLUEBERRY INCONYISWA NGAPHEZU KWE-PUMMELO YE-Chordoma KANYE NOKWELASHWA kwemisebe.

Khetha Nut BUTTERNUT noma BRAZIL NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Caffeine. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Butternut iyanconywa nge-Chordoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation. Lokhu kungenxa yokuthi i-Butternut ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela woMsebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-Brazil Nut yi-Ellagic Acid, i-Curcumin, i-Daidzein, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, Heat Stress Response kanye ne-MYC Signaling nezinye. I-Brazil Nut ayinconywa nge-Chordoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation ngoba iguqula lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBUTTERNUT INCONYISWA NGAPHEZU KWE-BRAZIL NUT NGE-Chordoma KANYE NOKWELASHWA kwemisebe.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abanengozi yofuzo yeChordoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma IKHABHISHI ELIMNYAMA?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, Cell Cycle, PI3K-AKT-MTOR Signaling kanye ne-Stem Cell Signaling nezinye. I-Butterbur Enkulu inconywa engcupheni ye-Chordoma lapho ingozi yofuzo ehlotshaniswa nayo i-CDKN2A. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Iklabishi Elimnyama yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Stem Cell Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Iklabishi Elimnyama alituswa uma ingozi yeChordoma uma ingozi yofuzo ehambisana nayo i-CDKN2A ngoba yandisa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYWA PHEZU KWEKHABHISHI ELIMNYAMA NGENGOZI YOFUZO YOMFUZA I-CDKN2A.

Khetha Isithelo NANCE noma i-MALUS (CRAB APPLE)?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling ne-Hypoxia nezinye. I-Nance inconywa engcupheni ye-Chordoma lapho ingozi yofuzo ehlotshaniswa nayo i-CDKN2A. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Malus (i-crab Apple) yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Malus (i-crab Apple) ayinconywa uma ingozi ye-Chordoma uma ingozi yofuzo ehambisana nayo i-CDKN2A ngoba inyusa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-MALUS (I-CRAB APPLE) NGE-CDKN2A GENETIC RISK OF CANCER.

Khetha Nut COMMON WALNUT noma EUROPEAN CHESTNUT?

I-Walnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, Cell Cycle, PI3K-AKT-MTOR Signaling kanye ne-Stem Cell Signaling nezinye. I-Walnut evamile inconywa engcupheni ye-Chordoma lapho ingozi yofuzo ehlotshaniswa nayo i-CDKN2A. Lokhu kungenxa yokuthi i-Common Walnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Quercetin, i-Lupeol, i-Ellagic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling nezinye. I-Chestnut yase-Europe ayinconywa uma ingozi ye-Chordoma uma ingozi yofuzo ehlotshaniswa nayo i-CDKN2A ngoba inyusa izindlela zayo zokusayina.

I-WALNUT EJWAYELEKILE INCONYISWA NGE-CHESTNUT YAseYurophu NGE-CDKN2A INGOZI YOFUZO YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njengeChordoma. Iziguli ze-Chordoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla kanye nezithako zokudla okunomsoco engizinconyelwe futhi ezingekho?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Chordoma, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Globe Artichoke kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukene wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli iChordoma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Ukuhlaziywa komdlavuza we-pan-cancer kuwo wonke ama-genomes.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• Inqubekelaphambili yocwaningo emiphumeleni yokulwa nomdlavuza kavithamini K2.
• I-Gallic acid idala ukulimala kwe-DNA futhi icindezela i-DNA yokulungisa isakhi sofuzo kumaseli omdlavuza womuntu we-prostate PC-3.
• Umphumela we-Daidzein kumdlavuza we-prostate refractory we-hormone in vitro kanye ne-vivo uma kuqhathaniswa ne-genistein ne-soy extract: amandla e-radiotherapy.
• Ukulawulwa okungekuhle kwe-transducer yesiginali kanye ne-activator ye-transcription-3 signaling cascade nge-lupeol ivimbela ukukhula futhi yenze i-apoptosis kumaseli e-hepatocellular carcinoma.
• https://www.ncbi.nlm.nih.gov/books/NBK430846
• https://my.clevelandclinic.org/health/diseases/17916-chordomas