Ukudla kwe-Protoplasmic Astrocytoma!

Isingeniso

Ukudla kwe-Protoplasmic Astrocytoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ku-Protoplasmic Astrocytoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza njenge-Protoplasmic Astrocytoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengeProtoplasmic Astrocytoma?

Isibonelo, ingabe kunendaba ukuthi iklabishi yemifino idliwa kakhulu uma iqhathaniswa ne-Horned Melon? Ingabe kuyawenza umehluko uma isithelo I-Sweet Cherry sithandwa kune-Nance? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-European Chestnut kanye nama-pulses afana ne-Gram Bean phezu kwe-Lima Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Protoplasmic Astrocytoma futhi ingabe impendulo efanayo yawo wonke umuntu onesimo esifanayo sokuxilongwa noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Protoplasmic Astrocytoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Sweet Cherry iqukethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin. Futhi i-Nance iqukethe izithako ezisebenzayo i-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin, i-Apigenin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Protoplasmic Astrocytoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Protoplasmic Astrocytoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Protoplasmic Astrocytoma?

Ukondleka komuntu siqu komdlavuza njenge-Protoplasmic Astrocytoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Protoplasmic Astrocytoma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Protoplasmic Astrocytoma

Wonke umdlavuza njenge-Protoplasmic Astrocytoma ungabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-Protoplasmic Astrocytoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana nokulungiswa kwe-DNA, i-Angiogenesis, i-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics iyingxenye yencazelo yesiginesha ye-Protoplasmic Astrocytoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Protoplasmic Astrocytoma zidinga ukuqaphela izindlela zesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kunconywa i-Protoplasmic Astrocytoma lapho uthatha ukwelashwa komdlavuza i-Temozolomide, futhi okunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TP53, IDH1, ATRX, FOXO3 kanye ne-TERT izakhi zofuzo ezisezingeni eliphezulu ezibikiwe ze-Protoplasmic Astrocytoma. I-TP53 ibikwa ku-46.8 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-IDH1 ibikwa ku-46.8%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. I-% yedatha yesiguli ikhonjwa njengabesilisa. I-Protoplasmic Astrocytoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Protoplasmic Astrocytoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha IKHABHISHI Lomifino noma IKHABE LE-HORNED?

Iklabishi Yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle, Cell Survival, P53 Signaling kanye ne-MAPK Signaling nezinye. Iklabishi liyanconywa nge-Protoplasmic Astrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi Iklabishi liguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Horned Melon yi-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana nokulungisa i-DNA, i-TGFB Signaling kanye ne-Oxidative Stress nezinye. I-Horned Melon ayinconywa nge-Protoplasmic Astrocytoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

IKABHISHI LEMIJINO KUNCONYWA NGAPHEZU KWEKHABBE LEZINKONDLO NGE-Protoplasmic Astrocytoma KANYE NOKWELASHWA I-Temozolomide.

Khetha i-Fruit NANCE noma i-SWEET CHERY?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, Hypoxia ne-P53 Signaling nezinye. I-Nance inconywa nge-Protoplasmic Astrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi uNance ulungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Sweet Cherry yi-Quercetin, i-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-Angiogenesis ne-Oxidative Stress nezinye. I-Sweet Cherry ayinconywa nge-Protoplasmic Astrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ISITHELO NANCE KUNCONYWA NGAPHEZU KWE-CHERY EMNANDI NGE-Protoplasmic Astrocytoma KANYE NOKWELASHWA I-Temozolomide.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Phloretin, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-DNA Repair, Cell Cycle, P53 Signaling kanye ne-Microtubule Dynamics nezinye. I-Butternut inconywa nge-Protoplasmic Astrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Quercetin, i-Curcumin, i-Ellagic Acid, i-Formononetin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling, i-WNT Beta Catenin Signaling kanye ne-Oxidative Stress nezinye. I-Chestnut yase-Europe ayinconyelwe i-Protoplasmic Astrocytoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

IBHUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT YAseYurophu NGE-Protoplasmic Astrocytoma KANYE NOKWELASHWA I-Temozolomide.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo ye-Protoplasmic Astrocytoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable BITTER GOURD noma i-ASPARAGUS?

I-Vegetable Bitter Gourd iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Catechol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Hypoxia, i-P53 Signaling, i-insulin Signaling kanye ne-Angiogenesis nezinye. I-Bitter Gourd inconyelwa engcupheni ye-Protoplasmic Astrocytoma lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Bitter Gourd inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Asparagus yemifino yi-Curcumin, i-Apigenin, i-Quercetin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Insulin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Asparagus ayinconywa uma ingozi ye-Protoplasmic Astrocytoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba yandisa izindlela zayo zokusayina.

IMINININGWANE EBITTER VEGETABLE INCONYISWA NGAPHEZU KWE-ASPARAGUS NGENGOZI YOFUZO YE-ATRX YOMKHANZA.

Khetha Isithelo SOUR CHERRY noma iPUMMELO?

I-Fruit Sour Cherry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Quercetin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Hypoxia, i-Angiogenesis ne-PI3K-AKT-MTOR Signaling nezinye. I-Sour Cherry inconywa engozini ye-Protoplasmic Astrocytoma lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Sour Cherry inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Curcumin, i-Apigenin, i-Quercetin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Insulin Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Pummelo ayinconywa uma ingozi ye-Protoplasmic Astrocytoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-FRUIT SOUR CHERRY INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YOMDLALO YE-ATRX.

Khetha i-Nutt COMMON WALNUT noma i-CHESTNUT?

I-Walnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Ellagic Acid, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-P53 Signaling, i-insulin Signaling ne-Angiogenesis nezinye. I-Walnut evamile inconywa engcupheni ye-Protoplasmic Astrocytoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Common Walnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Curcumin, i-Apigenin, i-Ellagic Acid, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Insulin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Chestnut ayinconywa uma ingozi ye-Protoplasmic Astrocytoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zesiginesha.

I-WALNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT NGENGOZI YE-ATRX GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Protoplasmic Astrocytoma. Iziguli ze-Protoplasmic Astrocytoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Protoplasmic Astrocytoma, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana neklabishi kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Protoplasmic Astrocytoma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• Imiphumela kanye nokubaluleka kwe-formononetin emazingeni e-HIF-1α kanye ne-VEGF kumathishu omdlavuza womlomo wesibeletho wegundane.
• Umphumela we-Daidzein kumdlavuza we-prostate refractory we-hormone in vitro kanye ne-vivo uma kuqhathaniswa ne-genistein ne-soy extract: amandla e-radiotherapy.
• Umsebenzi we-In vitro kanye ne-in vivo we-antitumor we-neochlorogenic acid emangqamuzaneni e-gastric carcinoma yomuntu ahambisana nesizukulwane se-ROS, ukulahlekelwa amandla olwelwesi lwe-mitochondrial kanye nokungeniswa kwe-apoptosis.