Ukudla Kwe-Prostate Small Cell Carcinoma!

Isingeniso

Ukudla Kwe-Prostate Small Cell Carcinoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Nge-Prostate Small Cell Carcinoma ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza ofana ne-Prostate Small Cell Carcinoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-Prostate Small Cell Carcinoma?

Isibonelo, ingabe kunendaba ukuthi iCalabash yemifino idliwa kakhulu uma iqhathaniswa netheniphu? Ingabe kuyawenza umehluko uma isithelo iNanking Cherry sithandwa kuneHighbush Blueberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Chestnut phezu kwe-European Chestnut kanye nama-pulses afana neChickpea phezu kwe-Catjang Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe I-Prostate Small Cell Carcinoma futhi ingabe impendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Prostate Small Cell Carcinoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Nanking Cherry iqukethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Daidzein, i-Caffeine, i-Formononetin. Futhi i-Highbush Blueberry iqukethe izithako ezisebenzayo i-Curcumin, i-Ellagic Acid, i-Cianidanol, i-Apigenin, i-Daidzein futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Prostate Small Cell Carcinoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Prostate Small Cell Carcinoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Kwe-Prostate Small Cell Carcinoma?

Ukondleka komuntu siqu komdlavuza njenge-Prostate Small Cell Carcinoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-Prostate Small Cell Carcinoma, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene nokwelashwa okungayeka ukusebenza ngakho.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Prostate Small Cell Carcinoma

Yonke imidlavuza efana ne-Prostate Small Cell Carcinoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Prostate Small Cell Carcinoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Oncogenic Histone Methylation, i-Oncogenic Cancer Epigenetics, i-PI3K-AKT-MTOR Signaling, I-Cell Cycle Checkpoints iyingxenye yencazelo yesiginesha ye-Prostate Small Cell Carcinoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenza ngempumelelo kwe-Prostate Small Cell Carcinoma kudingeka kuqashelwe izindlela ezihambisana namakhemikhali we-biochemical esigulini ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kunconyelwe i-Prostate Small Cell Carcinoma lapho uthatha ukwelashwa komdlavuza i-Abiraterone Acetate, nokunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-APC, i-PIK3CD, i-BRCA2, i-CREBBP ne-DNMT3B yizakhi zofuzo ezikleliswe phezulu ze-Prostate Small Cell Carcinoma. I-APC ibikwa ku-100.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-PIK3CD ibikwa ku-100.0 %. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. I-100.0 % yemininingwane yesiguli ihlonzwa njengabesilisa. I-Prostate Small Cell Carcinoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Prostate Small Cell Carcinoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha imifino CALABASH noma i-TURNIP?

I-Vegetable Calabash iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Daidzein, i-Formononetin, i-Salicylic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, i-Histone/Protein Acetylation, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Calabash inconywa nge-Prostate Small Cell Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate. Lokhu kungenxa yokuthi i-Calabash iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze zibonise umphumela we-Abiraterone Acetate.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-turnip yemifino yi-Curcumin, i-Ellagic Acid, i-Daidzein, i-Formononetin, i-Salicylic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana nokulungiswa kwe-DNA kanye ne-Growth Factor Signaling nezinye. Itheniphu ayinconyelwe kwi-Prostate Small Cell Carcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-Vegetable CALABASH INCONYISWA PHEZU KWE-JINIKA YE-Prostate Small Cell Carcinoma KANYE NOKWELASHWA I-Abiraterone Acetate.

Khetha Isithelo HIGHBUSH BLUEBERRY noma NANKING CHERY?

I-Fruit Highbush Blueberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Ellagic Acid, i-Cianidanol, i-Apigenin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Growth Factor Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Highbush Blueberry inconywa ku-Prostate Small Cell Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate. Lokhu kungenxa yokuthi i-Highbush Blueberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze zibonise umphumela we-Abiraterone Acetate.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni seNanking Cherry yiCurcumin, Apigenin, Daidzein, Caffeine, Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Nanking Cherry ayinconywa nge-Prostate Small Cell Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate ngoba kushintsha lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO I-HIGHBUSH BLUEBERRY INCONYISWA NGAPHEZU KWE-NANKING CHERRY YE-Prostate Small Cell Carcinoma KANYE NOKWELASHWA I-Abiraterone Acetate.

Khetha Nut CHESTNUT noma EUROPEAN CHESTNUT?

I-Chestnut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Ellagic Acid, i-Apigenin, i-Daidzein, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Growth Factor Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Chestnut iyanconywa nge-Prostate Small Cell Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate. Lokhu kungenxa yokuthi i-Chestnut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze zibonise umphumela we-Abiraterone Acetate.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Curcumin, i-Ellagic Acid, i-Apigenin, i-Daidzein, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Chestnut yase-Europe ayinconywa nge-Prostate Small Cell Carcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Abiraterone Acetate ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-CHESTNUT INCONYISWA NGE-CHESTNUT YAseYurophu Ye-Prostate Small Cell Carcinoma KANYE NOKWELASHWA I-Abiraterone Acetate.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-Prostate Small Cell Carcinoma noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithasiselo ziba zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha I-Vegetable GIANT BUTTERBUR noma I-MUSTARD YASE-CHINESE?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling, i-Histone/Protein Acetylation, i-P53 Signaling ne-Angiogenesis nezinye. I-Butterbur Enkulu inconywa engcupheni ye-Prostate Small Cell Carcinoma lapho ingozi yofuzo ehlotshaniswa nayo kuyi-APC. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Mustard yaseShayina yemifino yi-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chinese Mustard ayinconywa uma ingozi ye-Prostate Small Cell Carcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI KUNCONYWA NGAPHEZU KWEMISTADI YASECHINE NGENGOZI YOFUZO YOMFUZA YE-APC.

Khetha Isithelo JAVA PLUM noma CHOKECHERRY EVAMILE?

I-Fruit Java Plum iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling, Stem Cell Signaling, i-Histone/Protein Acetylation kanye ne-P53 Signaling nezinye. I-Java Plum iyanconywa ngengozi ye-Prostate Small Cell Carcinoma lapho ubungozi bofuzo obuhlobene kuyi-APC. Lokhu kungenxa yokuthi i-Java Plum inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Chokecherry Evamile yi-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling ne-Angiogenesis nezinye. I-Chokecherry Evamile ayinconywa uma ingozi ye-Prostate Small Cell Carcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC ngoba yandisa izindlela zayo zokusayina.

ISITHELO I-JAVA PLUM INCONYISWA NGAPHEZU KWE-CHOKECHERRY EJWAYELEKILE KU-APC GENETIC RISK OF CANCER.

Khetha Nut CHIA noma HICKORY NUT?

I-Chia iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-TGFB Signaling, i-Histone/Protein Acetylation, i-Angiogenesis ne-DNA Repair nezinye. I-Chia inconywa engcupheni ye-Prostate Small Cell Carcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC. Lokhu kungenxa yokuthi i-Chia inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Hickory Nut yi-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Ukusayina kwe-TGFB kanye ne-WNT Beta Catenin Signaling nezinye. I-Hickory Nut ayinconywa uma ingozi ye-Prostate Small Cell Carcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC ngoba inyusa izindlela zayo zokusayina.

I-CHIA INCONYISWA NGAPHEZU KWE-HICKORY NUT YE-APC GENETIC RISK OF CANCER.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Prostate Small Cell Carcinoma. Iziguli ze-Prostate Small Cell Carcinoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo enginconyelwe kona futhi okungenjalo?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Prostate Small Cell Carcinoma, ngayinye enezakhi zofuzo zesimila esinokwehluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Calabash kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli I-Prostate Small Cell Carcinoma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
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• Ukuhlaziywa kwe-molecular docking ye-Cianidanol evela ku-Ginkgo biloba enethagethi yomdlavuza webele we-HER2+.
• Ukuguquguquka kwenkulumo ye-HER2 nge-ferulic acid kumaseli womdlavuza webele womuntu we-MCF7.
• I-Betulin Ivimbela I-Metastasis Yamaphaphu Ngokufaka Ukuboshwa Komjikelezo Weseli, Ukuzilawula Kwe-Autophagy, kanye ne-Apoptosis yamaseli omdlavuza we-Metastatic Colorectal.
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• Imiphumela yokuvikela iqhathaniswa nokuphromotha yetiye elimhlophe ne-caffeine ku-PhIP-induced tumorigenesis kanye nokuvezwa kwe-beta-catenin kugundane.