Ngowuphi umhlaza onokuzuza ngokuquka iAloe Vera ekutyeni kwabo?

Iimbalasane

Ikhala lamkelwa ngokubanzi ngezibonelelo zalo zempilo kwaye lisetyenziswa rhoqo zizigulana ezinomhlaza kunye nabo basengozini yemfuzo. Nangona kunjalo, ukhuseleko kunye nokusebenza kweAloe Vera kwizigulana ezinomhlaza kuxhomekeke kwizinto ezininzi ezifana nomhlaza, ichemotherapy, olunye unyango, kunye nemfuzo yethumba. Ukwazi ukuba ezinye ukutya kunye nezongezelelo, ezinje ngegrapefruit kunye nesipinatshi, zinokusebenzisana kakubi namayeza omhlaza kwaye zibangele ukusabela okubi kubalulekile.

Ukutya kubaluleke kakhulu kunyango lomhlaza njengoko kunokuchaphazela iziphumo zonyango. Izigulana ezinomhlaza kufuneka zikhethe ngononophelo kwaye zifake ukutya okufanelekileyo kunye nezongezo kwizidlo zabo. Umzekelo, iAloe Vera inokuba luncedo kwabo banePrayimari yePenile Squamous Cell Carcinoma befumana iMitomycin, kodwa isenokungalungeli kwizigulana ezifumana i-Ifosfamide yePrimary Round Cell Sarcoma. Ngaphaya koko, ngeli lixa iAloe Vera inokunceda abantu abanomngcipheko wemfuzo “CDH1”, ayinakucetyiswa kwabo banengozi yemfuzo eyahlukileyo. Ukwenza izicwangciso zokutya ezisekelwe kwimpilo, unyango, kunye nofuzo kubalulekile.

Ukuqonda ukuba ukwenza isigqibo malunga nokufaneleka kweAloe Vera kwisigulana somhlaza kufuneka kube ngumntu ngamnye kubalulekile. Izinto ezibalulekileyo ezifana nohlobo lomhlaza, iindlela zonyango, ukwakheka kwemfuzo, umngcipheko wemfuza, ubudala, ubunzima bomzimba, kunye nendlela yokuphila zibalulekile ekwenzeni isigqibo sokuba iAloe Vera lukhetho olufanelekileyo. I-Genomics kunye ne-genomics, ngokukodwa, yingqwalasela ebalulekileyo. Kuba ezi zinto zinokuvela, kubalulekile ukuphonononga rhoqo kwaye ulungelelanise ukhetho lokutya ukuhambelana notshintsho kwisimo sempilo kunye nonyango.

Ukuqukumbela, indlela ebanzi yokhetho lokutya ibalulekile, igxile kwiziphumo ezipheleleyo zazo zonke izinto ezisebenzayo ekutyeni / nezongezo ezifana neAloe Vera endaweni yokuvavanya isithako ngasinye esisebenzayo ngokwahlukileyo okanye ukungayihoyi ngokupheleleyo. Lo mbono ubanzi ukhuthaza indlela enengqiqo nenzululwazi kwisicwangciso sokutya somhlaza.

Uluhlu olufutshane

Ukusetyenziswa kokutya okusekelwe kwizityalo kunye nezongezelelo, ezinje ngeevithamini, imifuno, iiminerali, iiprobiotics, kunye nezongezelelo ezahlukeneyo ezikhethekileyo, ziyenyuka phakathi kwabaguli abanomhlaza. Ezi zongezo ziyilelwe ukuhambisa ugxininiso oluphezulu lwezithako ezithile ezisebenzayo, uninzi lwazo zikwakukutya okwahlukeneyo. Ugxininiso kunye nokwahlukana kwezithako ezisebenzayo ziyahluka phakathi kokutya okupheleleyo kunye nezongezelelo. Ukutya ngokuqhelekileyo kunika uluhlu lwezithako ezisebenzayo kodwa kwiindawo ezisezantsi, ngelixa izongezelelo zibonelela ngoxinzelelo oluphezulu lwezithako ezithile.

Ukuthathela ingqalelo imisebenzi eyahlukeneyo yesayensi kunye neyebhayoloji yesithako ngasinye esisebenzayo kwinqanaba leemolekyuli, kubalulekile ukunika ingxelo ngeziphumo ezidityanisiweyo zala malungu xa uthatha isigqibo malunga nokutya kunye nezongezo eziza kutyiwa okanye hayi.

Umbuzo obalulekileyo ophakamayo: Ngaba kufuneka udibanise iAloe Vera kwisidlo sakho njengento yokutya okanye isongezelelo? Ngaba kuyacetyiswa ukuba utye iAloe Vera ukuba unemfuzo enokuthanani nomhlaza onxulunyaniswa ne-CDH1 gene? Kuthekani ukuba endaweni yoko umngcipheko wakho wemfuza usuka kumfuza? Ngaba kuluncedo ukuquka iAloe Vera ekutyeni kwakho ukuba ufunyaniswe unePrimary Round Cell Sarcoma, okanye ukuba uxilongo lwakho yiPrimary Penile Squamous Cell Carcinoma? Ngaphezu koko, kufuneka kuhlengahlengiswe njani ukusetyenziswa kwakho kweAloe Vera ukuba ufumana unyango lwe-Mitomycin okanye ukuba isicwangciso sakho sonyango siyatshintsha sisuka kwi-Mitomycin siye kwi-Ifosfamide? Kubalulekile ukuqonda ukuba iinkcazo ezilula ezifana 'neAloe Vera yendalo, ngoko ke isoloko iluncedo' okanye 'iAloe Vera yonyusa ukhuselo lomzimba' akonelanga kukhetho lokutya / lokongezelela.

Ukongeza, kubalulekile ukuphinda uhlole ukufaneleka kokuquka iAloe Vera kukutya kwakho ukuba kukho utshintsho kwirejimeni yonyango lwakho. Isishwankathelo, xa usenza izigqibo malunga nokubandakanya ukutya okanye izongezo ezinje ngeAloe Vera kwisondlo sakho ngenxa yezibonelelo zayo, kuya kufuneka uqwalasele iziphumo ezipheleleyo ze-biochemical yazo zonke izithako, uqwalasele izinto ezifana nohlobo lomhlaza, unyango oluthile olwenzayo, imfuzo. izinto ezilindelekileyo, kunye nokukhetha indlela yokuphila.

Cancer

Umhlaza usengumceli mngeni obalulekileyo kwicandelo lezonyango, ngokufuthi ubangela unxunguphalo oluxhaphakileyo. Nangona kunjalo, ukuqhubela phambili kwamva nje kuye kwaphucula iziphumo zonyango, ngakumbi ngeendlela zonyango zomntu, iindlela zokujonga ezingaphazamisiyo kusetyenziswa igazi kunye neesampulu zamathe, kunye nophuhliso lwe-immunotherapy. Ukufunyaniswa kwangethuba kunye nokungenelela kwangethuba kuye kwaba yinto ebalulekileyo ekuphembeleleni ngokufanelekileyo iziphumo zonyango ngokubanzi.

Uvavanyo lwemfuzo lunikeza isithembiso esibalulekileyo ekuvavanyeni umngcipheko womhlaza kunye nokuba sesichengeni kwangoko. Nangona kunjalo, kubantu abaninzi abaneemeko zosapho kunye nemfuzo kumhlaza, ukhetho longenelelo lonyango, nokuba lubekwe esweni rhoqo, luhlala lulinganiselwe okanye alukho. Emva kokuba ufumene uhlobo oluthile lomhlaza, njenge-Primary Penile Squamous Cell Carcinoma okanye i-Primary Round Cell Sarcoma, izicwangciso zonyango kufuneka zenziwe ngokwezifiso ngokusekelwe kwi-tumor genetics yomntu, isigaba sesifo, kunye nezinto ezifana nobudala kunye nesini. ”

Emva konyango, ukubeka iliso okuqhubekayo kubalulekile ukuze kubonwe naziphi na iimpawu zokubuyela kwakhona komhlaza kunye nokwazisa izigqibo ezilandelayo. Uninzi lwezigulana ezinomhlaza kunye nabo basemngciphekweni bahlala befuna iingcebiso malunga nokubandakanya ukutya okuthile kunye nezongezo kwizidlo zabo, ezidlala indima ebalulekileyo kwinkqubo yabo yokuthatha isigqibo malunga nolawulo lwezempilo.

Umbuzo obalulekileyo ngowokuba ingaba kunokubangela umngcipheko wemfuza kunye noxilongo oluthile lomhlaza xa uthatha isigqibo malunga nokhetho lokutya, olufana neAloe Vera. Ngaba umngcipheko wemfuzo womhlaza osuka kutshintsho kwi-CDH1 unefuthe elifanayo le-biochemical pathway njengokuguqulwa kwemfuza? Ukusuka kwimbono yesondlo, ngaba umngcipheko ohambelana nePrayimari yePenile Squamous Cell Carcinoma ilingana nePrimary Round Cell Sarcoma? Ngaphaya koko, ngaba uqwalaselo lokutya luhlala lufana kwabo bafumana i-Ifosfamide njengakwabo bafumana iMitomycin? Ezi ngqwalasela zibalulekile ekwenzeni ukhetho lokutya olunolwazi lwabantu abaneengozi ezahlukeneyo zemfuza kunye nonyango lomhlaza.

I-Aloe Vera-Isongezelelo seZondlo

I-Aloe Vera eyongeziweyo iquka uluhlu lwezithako ezisebenzayo, kuquka i-Lupeol, i-Chrysophanol, i-Barbaloin kunye ne-Acemannan, nganye ikhoyo kwiimpawu ezahlukeneyo. Ezi zithako zinefuthe kwiindlela ze-molecular, ngokukodwa i-WNT Beta Catenin Signaling, i-DNA Repair, i-PI3K-AKT-MTOR yokuSayina kunye ne-Adherens junction, elawula imiba ebalulekileyo yomhlaza kwinqanaba leeselula, ezifana nokukhula kwethumba, ukusasazeka, kunye nokufa kweeseli. Ukunika le mpembelelo yebhayoloji, ukukhetha izongezo ezifanelekileyo njengeAloe Vera, iyodwa okanye ngokudibeneyo, iba sisigqibo esibalulekileyo kwimeko yesondlo somhlaza. Xa ucinga ukusebenzisa iAloe Vera kumhlaza, kubalulekile ukuqwalasela ezi zinto zahlukeneyo kunye neendlela. Oku kungenxa yokuba, ngokufana nonyango lomhlaza, ukusetyenziswa kweAloe Vera ayisosigqibo sehlabathi lonke esilungele zonke iimhlaza kodwa kufuneka ibe yeyomntu.

Ukukhetha izongezo zeAloe Vera

Ukuphendula umbuzo othi 'Ndingaliphepha nini iAloe Vera kwimeko yoMhlaza' kulucelomngeni kuba impendulo yeyomntu ngamnye kakhulu - ngokulula 'Kuxhomekeke!'. Ngokufana nendlela naluphi na unyango lomhlaza olunokuthi lungasebenzi kwisigulana ngasinye, ukubaluleka kunye nokhuseleko okanye iinzuzo zeAloe Vera ziyahluka ngokuxhomekeke kwiimeko zomntu. Imiba efana nohlobo oluthile lomhlaza, imfuzo, unyango lwangoku, ezinye izongezo ezithathwayo, indlela yokuphila, iBMI, kunye nayo nayiphi na i-allergies zonke zidlala indima ekumiseleni ukuba iAloe Vera ifanelekile okanye kufuneka iphetshwe, kubethelela ukubaluleka koqwalaselo lomntu. kwizigqibo ezinjalo.

1. Ngaba izongezo zeAloe Vera ziya kuxhamla kwiZigulana zeSarcoma eziPhambili eziphantsi konyango lwe-Ifosfamide?

I-Primary Round Cell Sarcoma ibonakaliswe ngokuguqulwa kofuzo oluthile, okuyi-CIC, i-ATM kunye ne-FBXW7, ekhokelela ekuguquleni kwiindlela ze-biochemical pathways, ngokukodwa ukulungiswa kwe-DNA, i-Cell Cycle Checkpoints, i-Antigen Presentation kunye ne-Post Translation Modification. Ukusebenza konyango lomhlaza, olufana ne-Ifosfamide, kuxhomekeke kwindlela yayo yokusebenza kwezi ndlela zikhethekileyo. Esona sicwangciso sifanelekileyo siquka ukulungelelanisa isenzo sonyango kunye neendlela eziqhuba umhlaza, ngaloo ndlela kuqinisekiswa indlela yobuqu nesebenzayo. Kwiimeko ezinjalo, ukuphepha ukutya okanye izongezo zesondlo ezinokuchasa iziphumo zonyango okanye ukunciphisa olu lungelelwaniso kubalulekile. Ngokomzekelo, isongezelelo se-Aloe Vera, esichaphazela ukulungiswa kwe-DNA, isenokungabi lolona khetho lufanelekileyo kwimeko ye-Primary Round Cell Sarcoma xa i-Ifosfamide. Oku kungenxa yokuba isenokuthi iqhubele phambili ngakumbi isifo okanye iphazamise ukusebenza konyango. Xa ukhetha isicwangciso sesondlo, kubalulekile ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluqhubekayo, ubudala, isini, i-BMI, indlela yokuphila, kunye naluphi na utshintsho olwaziwayo lwemfuzo.

2. Ingaba izongezo zeAloe Vera ziyakuzinceda izigulana eziphantsi koNyango lweMitomycin?

I-Primary Penile Squamous Cell Carcinoma ichongiwe ngokuguqulwa kofuzo oluthile, njenge-ABRAXAS1, i-PIK3CB kunye ne-NUP93, ebangela utshintsho kwiindlela ze-biochemical pathways, ngokukodwa i-WNT Beta Catenin Signaling, i-Hematopoiesis kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, njengeMitomycin, kumiselwa kukudibana kwayo nezi ndlela. Injongo kukuqinisekisa ukuba unyango luhambelana kakuhle neendlela eziqhuba umhlaza, okwenza kube nendlela yonyango lomntu. Kulo mxholo, ukutya okanye izongezo ezihambelana nonyango okanye ukuphucula oku kulungelelaniswa kufuneka kuthathelwe ingqalelo. Ngokomzekelo, isongezelelo se-Aloe Vera lukhetho olunengqiqo kulabo abane-Primary Penile Squamous Cell Carcinoma ehamba ne-Mitomycin. Oku kungenxa yokuba iAloe Vera inefuthe kwiindlela ezifana ne-WNT Beta Catenin Signaling, enokuthi ithintele izinto eziqhuba iPrimary Penile Squamous Cell Carcinoma okanye izuze ukusebenza kweMitomycin.

3. Ingaba izongezo zeAloe Vera zikhuselekile kubantu abasempilweni abaneCDH1 Mutation Associated Genetic Risk?

I-CDH1 idlala indima ebalulekileyo kuvavanyo lomngcipheko womhlaza. Ukuguqulwa kwe-CDH1 kunokuphazamisa iindlela ezibalulekileyo ze-biochemical, kuquka i-Adherens junction kunye ne-Epithelial kwi-Mesenchymal Transition, echaphazela ukuphuhliswa komhlaza. Ukuba iphaneli yakho yemfuzo ityhila utshintsho kwi-CDH1 ehambelana noMhlaza weGastric, cinga ukufaka izongezo zeAloe Vera kwisicwangciso sakho sesondlo. Ezi zongezo zinokuphembelela ngokufanelekileyo iindlela ezifana ne-Adherens junction, inzuzo ngokubonelela ngenkxaso efanelekileyo kubantu abane-CDH1 yeenguqu kunye neenkxalabo zempilo ezinxulumene nazo.

Ukuququmbela

Ezona zinto zimbini zibalulekileyo ekufuneka uzikhumbule kukuba unyango lomhlaza kunye nesondlo azinakuze zifane kumntu wonke. Isondlo, kuquka ukutya kunye nezongezelelo ezifana neAloe Vera, sisixhobo esisebenzayo esinokulawulwa nguwe ngelixa ujongene nomhlaza.

"Ndingatya ntoni?" ngowona mbuzo udla ngokubuzwa ngabaguli abanomhlaza kunye nabo basemngciphekweni womhlaza. Impendulo echanekileyo kukuba ixhomekeke kwizinto ezifana nohlobo lomhlaza, imfuzo yethumba, unyango lwangoku, ukungezwani komzimba, indlela yokuphila, kunye ne-BMI.

Fumana isondlo sakho somhlaza kwi-addon ngokucofa ikhonkco elingezantsi kwaye uphendule imibuzo malunga nohlobo lomhlaza wakho, unyango, indlela yokuphila, i-allergies, ubudala, kunye nesini.

Ucaphulo

• I-Barbaloin Inciphisa Umonakalo we-Mucosal kwiiModeli zoMvavanyo ze-Rat Colitis ngokuLawula ukuvuvukala kunye ne-AMPK Signaling Pathway.
• cBioPortal for Cancer Genomics
• Ukwandiswa komsebenzi wokuchasana nokudumba kwe-Aloe vera i-adventitious extracts yeengcambu ngokuguqulwa kwee-metabolites eziphambili kunye nesibini nge-salicylic acid elicitation.
• Ukutsalwa, ukuhlanjululwa, iiMpawu zeZakhiwo, iMisebenzi ye-Biological kunye ne-Pharmacological Applications ye-Acemannan, i-Polysaccharide esuka kwi-Aloe vera: Uphononongo.
• Unyango lomhlaza lubumba ubume bokuqina be-clonal hematopoiesis.
• cBioPortal for Cancer Genomics
• Igolide-chrysophanol nanoparticles icinezela ukuqhubeka komhlaza wesibeleko somntu ngokungasebenzisi ukubonakaliswa kwe-AKT kunye nokukhuthaza i-apoptosis kunye ne-ROS isizukulwana kwi-vitro nakwi-vivo.
• Ukuxhatshazwa kwe-Mitomycin C okubangelwa yi-TCF-3 overexpression kwi-gastric cancer cell line MKN28 inxulumene ne-DT-diaphorase down-regulation.
• Ukutshintsha kwe-inverse kwisiseko se-DNA kunye nokulungiswa kwe-strand break negalelo ekuxhathiseni i-melphalan kwiiseli ezininzi ze-myeloma.
• I-Barbaloin: ingxelo emfutshane malunga nemiba yayo ye-pharmacological and analytical.