Ukutya kwe-Esophagogastric Adenocarcinoma!

intshayelelo

Ukutya kwe-Esophagogastric Adenocarcinoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Kwi-Esophagogastric Adenocarcinoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje nge-Esophagogastric Adenocarcinoma ingaba iyabaluleka na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje nge-Esophagogastric Adenocarcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno iWild Leek ityiwa kakhulu xa ithelekiswa neLettuce? Ngaba kuyawenza umahluko ukuba isiqhamo iMalabar Plum sikhethwa ngaphezu kweRaspberry eBomvu? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neHazelnut eqhelekileyo phezu kweChestnut kunye nezityalo ezifana nembotyi eBanzi phezu kwembotyi eluhlaza. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Esophagogastric Adenocarcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Esophagogastric Adenocarcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo i-Malabar Plum iqulethe izithako ezisebenzayo i-Curcumin, i-Formononetin, i-Lupeol, i-Phloretin, i-Daidzein. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Ellagic Acid, i-Quercetin, i-Curcumin, i-Formononetin, i-Lupeol kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Esophagogastric Adenocarcinoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi intsalela. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo se-Esophagogastric Adenocarcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Esophagogastric Adenocarcinoma?

Isondlo esilungiselelwe wena somhlaza njenge-Esophagogastric Adenocarcinoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Esophagogastric Adenocarcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Esophagogastric Adenocarcinoma

Yonke i-cancer efana ne-Esophagogastric Adenocarcinoma inokubonakaliswa ngeseti ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Esophagogastric Adenocarcinoma. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-mRNA Splicing, i-Oncogenic Cancer Epigenetics, i-PI3K-AKT-MTOR Ukubonakaliswa yinxalenye yenkcazo yesignesha ye-Esophagogastric Adenocarcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Esophagogastric Adenocarcinoma kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Esophagogastric Adenocarcinoma xa uthatha unyango lomhlaza Imitha, kunye nokunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-DNMT3A, i-PPM1D, i-CDKN2A, i-SMAD4 kunye ne-TET2 zezona ziphezulu iigenes ezixeliweyo ze-Esophagogastric Adenocarcinoma. I-DNMT3A ixelwe kwi-11.0 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye iPPM1D ichazwe kwi-3.2%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-23 ukuya kuma-89. I-75.2 % yedatha yezigulane ichongwe njengamadoda. I-Esophagogastric Adenocarcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Esophagogastric Adenocarcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable WILD LEEK okanye LETTUCE?

I-Vegetable Wild Leek iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, TGFB Signaling, i-NFKB Signaling kunye ne-Oxidative Stress kunye nabanye. I-Wild Leek icetyiswa kwi-Esophagogastric Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba i-Wild Leek ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo soMbane.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Lettuce yemifuno yi-Quercetin, i-Curcumin, i-Formononetin, i-Vitamin D3, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-lettuce ayikhuthazwa kwi-Esophagogastric Adenocarcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-LEEK YASEMHLANENI YEMIFUNO IYACEBISWA PHEZU KWELETHISI YE-Esophagogastric Adenocarcinoma KUNYE NONYANGO LWERadiation.

Khetha iSiqhamo RED RASPBERRY okanye MALABAR PLUM?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Quercetin, i-Curcumin, i-Formononetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-PI3K-AKT-MTOR Ukubonakaliswa kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Esophagogastric Adenocarcinoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwisiqhamo i-Malabar Plum yi-Curcumin, i-Formononetin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Oxidative Stress kunye nabanye. I-Malabar Plum ayikhuthazwa ukuba i-Esophagogastric Adenocarcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU IRASPBHARI IYANCEBISWA NGAPHEZU KWE-MALABAR PLUM YE-Esophagogastric Adenocarcinoma KUNYE NONYANGO lweRadiation.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, ukulungiswa kwe-DNA, ukuPhathwa kwe-NFKB kunye noxinzelelo lwe-Oxidative kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kwi-Esophagogastric Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba iHazelnut eqhelekileyo iguqula ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Ellagic Acid, i-Curcumin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Oxidative Stress kunye nabanye. I-Chestnut ayikhuthazwa kwi-Esophagogastric Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiRadiation kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-HAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-CHESTNUT YE-Esophagogastric Adenocarcinoma KUNYE NONYANGO LWEmitha.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuza ye-Esophagogastric Adenocarcinoma okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or YAM?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Lycopene. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-CDKN2A. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Yam yemifuno yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Stem Cell Signaling kunye nezinye. I-Yam ayikhuthazwa xa umngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-CDKN2A kuba inyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO ICEBISIWE PHEZU KWE-YAM NGE-CDKN2A UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Nance icetyiswa kumngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-CDKN2A. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo yi-Apigenin, i-Curcumin, i-Lupeol, i-Quercetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Stem Cell Signaling kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wemfuzo uhambelana ne-CDKN2A kuba inyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO YE-CDKN2A GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Lycopene. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuSayina kwe-MAPK, ukulungiswa kwe-DNA, ukuPhathwa kweeseli ze-Stem kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Butternut iyacetyiswa kumngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-CDKN2A. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Quercetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Stem Cell Signaling kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Esophagogastric Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-CDKN2A kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERNUT KUCEBISIWE NGAPHEZU KWE-EUROPA CHESTNUT YE-CDKN2A UMNGCIPHEKO wofuzo woMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Esophagogastric Adenocarcinoma. Izigulana ze-Esophagogastric Adenocarcinoma kunye nabantu abanomngcipheko wemfuza bahlala benombuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Esophagogastric Adenocarcinoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neWild Leek kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Esophagogastric Adenocarcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

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