Ukutya kwe-Upper Tract Urothelial Carcinoma!

intshayelelo

Ukutya kwe-Upper Tract Urothelial Carcinoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Upper tract urothelial carcinoma, uhlobo lomhlaza ochaphazela umgca wendlela yomchamo ophezulu, ifuna uqwalaselo olucokisekileyo malunga nokuxilongwa, ukulinganisa kunye nonyango. Ulwahlulo lwe-ICD-10 luncedisa kumaxwebhu asemgangathweni. Ukubekwa kwesi sifo kubalulekile ekumiseleni i-prognosis kunye nonyango olukhokelayo, olubandakanya utyando kwaye lunokubandakanya ichemotherapy okanye i-immunotherapy, kuxhomekeke kwinkqubela phambili yomhlaza. Izikhokelo ezivela kumaqumrhu agunyazisiweyo afana ne-AUA (i-American Urological Association), i-NCCN (i-National Comprehensive Cancer Network), kunye ne-EAU (i-European Association of Urology) inikezela ngezikhokelo ezibanzi zolawulo lwe-upper tract urothelial carcinoma. Ezi zikhokelo zikwabandakanya ulandelelo kunye nezicwangciso zokucupha emva konyango ukuze kubekwe iliso lokuphindaphinda. I-prognosis kunye namazinga okusinda kwi-carcinoma ephezulu ye-urothelial iyahluka, kunye neziphumo ezixhomekeke kwinqanaba lokuxilongwa kunye nokusebenza kwonyango. Uxilongo lubandakanya indibaniselwano yovavanyo lweklinikhi kunye nophando lweradiyoloji, kunye neempawu ezifana ne-hematuria kunye neentlungu ezikhokelela kuvavanyo lokuqala. Ukuqonda inkcazo yekliniki ye-urothelial cell carcinoma kunye nokuthobela izikhokelo ezicetyiswayo zolawulo lwayo kubaluleke kakhulu ekuphuculeni ukhathalelo lwesigulane kunye nokuphucula iziphumo.

Kwi-Upper Tract Urothelial Carcinoma ingaba ayinamsebenzi ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje ngeUpper Tract Urothelial Carcinoma ingaba ayinamsebenzi ukuba kukutya ntoni na endingakutyiyo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngeUpper Tract Urothelial Carcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno iKai-lan ityiwa kakhulu xa ithelekiswa neSunburst Squash (pattypan Squash)? Ngaba kuyawenza umahluko ukuba isiqhamo seGrapefruit siyakhethwa kuneRowanberry eSweet? Kwakhona ukuba ukhetho olufanayo lwenzelwe amandongomane/imbewu efana neChia phezu kweWalnut yaseJapan kunye neepulses ezifana neYellow Wax Bean phezu kwePigeon Pea. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Upper Tract Urothelial Carcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya oyityayo imiba ye-Upper Tract Urothelial Carcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iGrapefruit iqulethe izithako ezisebenzayo iLuteolin, iPhloretin, iLupeol, iBergapten, i-Eugenol. Kwaye iRowanberry emnandi iqulethe izithako ezisebenzayo iQuercetin, iLuteolin, iApigenin, iPhloretin, iCaffeine kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Upper Tract Urothelial Carcinoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Upper Tract Urothelial Carcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Upper Tract Urothelial Carcinoma?

Izondlo zomntu zomhlaza ezifana ne-Upper Tract Urothelial Carcinoma iquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Upper Tract Urothelial Carcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Upper Tract Urothelial Carcinoma

Zonke ii-cancer ezifana ne-Upper Tract Urothelial Carcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Upper Tract Urothelial Carcinoma. Iindlela ze-Biochemical ezifana ne-Vitamin Metabolism, i-Cell Cycle, i-PI3K-AKT-MTOR Ukubonakaliswa, Ukubonakaliswa kwe-MAPK kuyingxenye yenkcazo yesignesha ye-Upper Tract Urothelial Carcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Upper Tract Urothelial Carcinoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Upper Tract Urothelial Carcinoma xa uthatha unyango lomhlaza i-Ifosfamide, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-FGFR3, i-KMT2D, i-KDM6A, i-TERT kunye ne-KMT2C zezona zibekwe phezulu kwimizila yemfuza exeliweyo ye-Upper Tract Urothelial Carcinoma. I-FGFR3 ixelwe kwi-10.2% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-KMT2D ixelwe kwi-7.6%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-38 ukuya kuma-88. Ama-64.9 % edatha yezigulane ichongwe njengamadoda. I-Upper Tract Urothelial Carcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo ze-Upper Tract Urothelial Carcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable KAI-LAN okanye SUNBURST SQUASH (PATTYPAN SQUASH)?

Imifuno ye-Kai-lan iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Apigenin, i-Phloretin, i-Caffeine, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Cell Cycle Checkpoints kunye nezinye. U-Kai-lan wenze isincomo kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide. Oku kungenxa yokuba uKai-lan ulungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo se-Ifosfamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Sunburst Squash (i-pattypan Squash) yi-Luteolin, i-Apigenin, i-Myricetin, i-Phloretin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial kwi-Mesenchymal Transition kunye ne-Oxidative Stress kunye nezinye. I-Sunburst Squash (i-pattypan Squash) ayikhuthazwa kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

I-KAI-LAN YOMFUNO ICEBISWA NGAPHEZU KWE-SUNBURST SQUASH (i-PATTYPAN SQUASH) YE-Upper Tract Urothelial Carcinoma KUNYE NONYANGO I-Ifosfamide.

Khetha iSiqhamo SWEET ROWANBERRY okanye iGRAPEFRUIT?

Isiqhamo Sweet Rowanberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Luteolin, i-Apigenin, i-Phloretin, i-Caffeine. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Sweet Rowanberry icetyiswa kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide. Oku kungenxa yokuba iRowanberry eSwiti ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Ifosfamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yiLuteolin, iPhloretin, iLupeol, iBergapten, i-Eugenol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. IGrapefruit ayikhuthazwa kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide kuba lulungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

ISIQHAMO ESWENZI I-ROWANBERRY IYACEBISWA NGAPHEZU KWEGRAPEFRUIT NGE-Upper Tract Urothelial Carcinoma KUNYE NONYANGO I-Ifosfamide.

Khetha Nut CHIA okanye JAPANESE WALNUT?

I-Chia iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Luteolin, i-Apigenin, i-Myricetin, i-Phloretin, i-Caffeine. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition, ukulungiswa kwe-DNA kunye ne-Vitamin Metabolism kunye nabanye. I-Chia icetyiswa kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide. Oku kungenxa yokuba i-Chia ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Ifosfamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Walnut yaseJapan yi-Luteolin, i-Apigenin, i-Ellagic Acid, i-Myricetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial kwi-Mesenchymal Transition kunye ne-Oxidative Stress kunye nezinye. IWalnut yaseJapan ayikhuthazwa kwi-Upper Tract Urothelial Carcinoma xa unyango lomhlaza oluqhubekayo i-Ifosfamide kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CHIA ICEBISIWE NGAPHEZU KWEWALNUT YASEJAPANE NGENXA YE-Upper Tract Urothelial Carcinoma KUNYE NONYANGO I-Ifosfamide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Upper Tract Urothelial Carcinoma okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha imifuno ye-CAULIFLOWER okanye i-SPINACH?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-P53 Signaling, i-MAPK yokuSayina kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Cauliflower icetyiswa kumngcipheko we-Upper Tract Urothelial Carcinoma xa ingozi yemfuzo ehambelana nayo yi-FGFR3. Oku kungenxa yokuba iCauliflower yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno Isipinashi yi-Apigenin, i-Curcumin, i-Quercetin, i-Myricetin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, i-MAPK yokuSayina kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. Isipinatshi asikhuthazwa xa umngcipheko we-Upper Tract Urothelial Carcinoma xa umngcipheko wezofuzo uhambelana ne-FGFR3 kuba yonyusa iindlela zokutyikitya kuyo.

I-CAULIFLOWER YOMFUNO INCEBISWA NGAPHEZU KWESIPINACH NGEFGFR3 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Formononetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-P53 Signaling, i-MAPK yokuSayina kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Red Raspberry iyacetyiswa kumngcipheko we-Upper Tract Urothelial Carcinoma xa umngcipheko wemfuzo ohambelana ne-FGFR3. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Formononetin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR yokuSayina, iiNdawo zokuHlola zeSeli kunye ne-MYC yokuSayina kunye nabanye. IPummelo ayikhuthazwa xa umngcipheko we-Upper Tract Urothelial Carcinoma xa umngcipheko wezofuzo uhambelana ne-FGFR3 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO ESIQINISEKISO PHEZU KWE-PUMMELO NGE-FGFR3 GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Formononetin, i-Lycopene. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-JAK-STAT Signaling, i-P53 Signaling, i-MAPK yokuSayina kunye ne-Cell Cycle Checkpoints kunye nabanye. I-Hazelnut eqhelekileyo icetyiswa kumngcipheko we-Upper Tract Urothelial Carcinoma xa ingozi yemfuzo ehambelana nayo yi-FGFR3. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Myricetin, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR yokuSayina, iiNdawo zokuHlola zeSeli kunye ne-MYC yokuSayina kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Upper Tract Urothelial Carcinoma xa umngcipheko wezofuzo uhambelana ne-FGFR3 kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWE-CHESTNUT NGE-FGFR3 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Upper Tract Urothelial Carcinoma. Izigulana ze-Urothelial Carcinoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Upper Tract Urothelial Carcinoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Kai-lan kuqulethe i-bioactives eyohlukeneyo ngokwemiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Upper Tract Urothelial Carcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• UFikelelo lweMsk 2021
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• I-Phloretin icinezela i-metastasis ngokujolisa kwi-protease kwaye inqanda ukuqina komhlaza kunye ne-angiogenesis kwiiseli zomhlaza womlomo wesibeleko.
• I-citrus flavonoid naringenin ivuselela ukulungiswa kwe-DNA kwiiseli zomhlaza we-prostate.
• I-Brassinin inqanda indlela yokubonisa i-STAT3 ngokumodareyithwa kwe-PIAS-3 kunye ne-SOCS-3 intetho kwaye inike amandla i-xenograft yomhlaza wemiphunga yabantu kwiimpuku ezinqunu ukuya kwi-paclitaxel.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.