Ukutya kweMelanoma!

intshayelelo

Ukutya kweMelanoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Imelanoma luhlobo lomhlaza wolusu olusuka kwiimelanocytes, eziziseli ezivelisa umbala webala. Lolona hlobo luyingozi lomhlaza wolusu yaye unokunwenwela ngokukhawuleza kwamanye amalungu omzimba ukuba awunyangwa. I-Melanoma inokuthi yenze kwiliso elaziwa ngokuba yi-ocular melanoma nangaphakathi empumlweni, emlonyeni, emqaleni, kwindawo yangasese okanye ezimpundu, eyaziwa ngokuba yi-mucosal melanoma. Iimpawu ze-melanoma zingabandakanya utshintsho kwimilo, umbala, okanye ubukhulu be-moles ekhoyo, ukubonakala kwee-moles ezintsha, okanye ukuphuhliswa kwezilonda ezingaphiliyo. Unyango lwemelanoma luxhomekeke kwinqanaba kwaye lunokubandakanya utyando, unyango lwemitha, ichemotherapy, okanye unyango olujoliswe kuyo. Kubalulekile ukuqaphela izinto ezinobungozi ezinxulumene ne-melanoma, kubandakanywa ufuzo kunye nokuvela elangeni, kunye nokuthatha amanyathelo okhuseleko afana nokunxiba i-sunscreen kunye nempahla yokukhusela. Ukuzihlola rhoqo, kunye nokuhlolwa kwe-dermatologist, kunokunceda ekuxilongweni kwangaphambili kunye nokuphucula izinga lokusinda kwe-melanoma.

Ngaba iMelanoma ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neMelanoma ingaba ibalulekile into yokuba kukutya endikutyayo okanye endingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwizityalo ngaba kwanele umhlaza onje ngeMelanoma?

Umzekelo ingaba inomsebenzi ukuba iCauliflower yemifuno ityiwa kakhulu xa ithelekiswa nePokeweed yaseMelika? Ngaba kuyawenza umahluko ukuba isiqhamo iMalabar Plum siyakhethwa kuneBlack Mulberry? Kwakhona ukuba ukhetho olufanayo lwenzelwe amandongomane/imbewu efana neButternut ngaphezulu kweChestnut yaseYurophu kunye nezityalo ezifana neBroad Bean phezu kwePigeon Pea. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwiMelanoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiMelanoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iMalabar Plum iqulethe izithako ezisebenzayo iMyricetin, iLycopene, iCurcumin, i-Isoliquiritigenin, iCinnamaldehyde. Kwaye i-Black Mulberry iqulethe izithako ezisebenzayo i-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo nokukhetha ukutya oza kukutya ngenxa yeMelanoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungazihoyi ezinye. Kuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seMelanoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiMelanoma?

Isondlo esilungiselelwe wena somhlaza onje ngeMelanoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yeMelanoma, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMelanoma

Yonke imihlaza efana neMelanoma inokuphawulwa ngeseti eyodwa yeendlela zebhayomichiza - iindlela zokutyikitya zeMelanoma. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-Inositol Phosphate Signaling, i-Extracellular Matrix Remodelling, i-Focal Adhesion iyingxenye yenkcazo yesignesha ye-Melanoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Melanoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali enxulumene nesigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiMelanoma xa uthatha unyango lomhlaza iDabrafenib, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MUC16, i-BRAF, i-APOB, i-MGAM kunye ne-NRAS zezona ntlobo zemfuza ezixeliweyo eziphezulu zeMelanoma. I-MUC16 ixelwe kwi-7.5 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye iBRAF ixelwe kwi-4.9%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kwi-5 ukuya kuma-90. I-62.8 % yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeMelanoma kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenza isondlo somntu.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMelanoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CAULIFLOWER okanye AMERICAN POKEWEED?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde, i-Formononetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, i-Amino Acid Metabolism kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. ICauliflower iyacetyiswa ngeMelanoma xa unyango lomhlaza oluqhubekayo luyiDabrafenib. Oku kungenxa yokuba iCauliflower iguqula ezo ndlela zebhayomikhali ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seDabrafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yase-American Pokeweed yi-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. I-American Pokeweed ayikhuthazwa kwi-Melanoma xa unyango lomhlaza oluqhubekayo yi-Dabrafenib kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CAULIFLOWER YOMFUNO INCEBISIWE NGAPHEZU KWE-POKEWEED YAseMelika YE-Melanoma KUNYE NONYANGO I-Dabrafenib.

Khetha iSiqhamo EMNYAMA IMULBERRY okanye iMLABAR PLUM?

Isiqhamo se-Mulberry emnyama siqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-Growth Factor Signaling kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Black Mulberry iyacetyiswa kwiMelanoma xa unyango lomhlaza oluqhubekayo yi-Dabrafenib. Oku kungenxa yokuba Iqunube eliMnyama lilungisa iindlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seDabrafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwisiqhamo i-Malabar Plum yiMyricetin, iLycopene, iCurcumin, i-Isoliquiritigenin, iCinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. I-Malabar Plum ayikhuthazwa kwiMelanoma xa unyango lomhlaza oluqhubekayo yi-Dabrafenib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

ISIQHAMO OMNYAMA EMNYAMA KUNCEBISWA NGAPHEZU KWE-MALABAR PLUM YE-Melanoma KUNYE NONYANGO I-Dabrafenib.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neMyricetin, iLycopene, iCurcumin, i-Isoliquiritigenin, iCinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, ukulungiswa kwe-DNA kunye nokuSayina kwe-insulin kunye nabanye. I-Butternut yenziwa isincomo kwiMelanoma xa unyango lomhlaza oluqhubekayo luyi-Dabrafenib. Oku kungenxa yokuba i-Butternut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo se-Dabrafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Myricetin, i-Curcumin, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-WNT Beta Catenin Signaling, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Oxidative Stress kunye nabanye. I-Chestnut yaseYurophu ayicetyiswa ukuba i-Melanoma xa unyango lomhlaza oluqhubekayo yi-Dabrafenib kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

IBHUTTERNUT IYAYINGCEBISWA NGAPHEZU KWE-EUROPE-CHESTNUT NGE-Melanoma KUNYE NONYANGO I-Dabrafenib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuzo ye-Melanoma okanye imbali yosapho "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or TURNIP?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-MYC Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. IButterbur enkulu iyacetyiswa kumngcipheko weMelanoma xa umngcipheko wemfuzo ohambelana ne-APOB. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Turnip yemifuno yi-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Cell Cycle kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. Itheniphu ayikhuthazwa xa umngcipheko weMelanoma xa umngcipheko wemfuzo unxulunyaniswa ne-APOB kuba yonyusa iindlela zokutyikitywa kwayo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA NGAPHEZU KWEJIKO LOMNGCIPHEKO WE-APOB genetics WOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-Growth Factor Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Red raspberry iyacetyiswa kumngcipheko we-Melanoma xa umngcipheko wemfuzo ohambelana ne-APOB. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints kunye ne-Extracellular Matrix Remodeling kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko weMelanoma xa umngcipheko wemfuzo unxulunyaniswa ne-APOB kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO SESIQINISEKISO PHEZU KWE-PUMMELO NGE-APOB genetic RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye MACADAMIA NUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-Growth Factor Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko weMelanoma xa umngcipheko wemfuzo ohambelana ne-APOB. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Macadamia Nut yi-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Macadamia Nut ayikhuthazwa xa umngcipheko we-Melanoma xa umngcipheko wemfuzo unxulumene ne-APOB kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWE-MACADAMIA NUT YE-APOB genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neMelanoma. Izigulana zeMelanoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Melanoma, nganye inemfuza eyahlukileyo ye-tumor enolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neCauliflower kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon senza ukuba isigqibo sibe lula kwaye sisuse lonke uqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakukhetheli iMelanoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• I-2018
• I-Curcuminoids yenza i-Reactive Oxygen Species kunye ne-Autophagy yokuphucula i-Apoptosis kwiiseli zoMhlaza woMlomo woMntu.
• I-Morsin ibangela ukufa kweeseli ngokungasebenzisi umqondiso we-STAT3 kwiiseli zomhlaza wedlala lobudoda.
• Ukuthathwa kwe-mulberry 1-deoxynojirimycin kuthintela umhlaza we-colorectal kwiimpuku.
• I-Brassinin icinezela amandla okuHlabaza okuHlangeneyo kweeSeli ze-Lung Carcinoma ngoKucinywa kwe-PI3K/Akt/mTOR I-Signaling Cascade.
• I-Vitamin C ibulala iiseli zomhlaza we-thyroid ngokusebenzisa inhibition exhomekeke kwi-ROS ye-MAPK / ERK kunye ne-PI3K / AKT iindlela ngeendlela ezahlukeneyo.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• https://www.ncbi.nlm.nih.gov/books/NBK470409
• https://www.cancer.org/cancer/types/melanoma-skin-cancer/about/what-is-melanoma.html