Ukutya kweMedulloblastoma!

intshayelelo

Ukutya kwe-Medulloblastoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Medulloblastoma luhlobo lwe-tumor yengqondo enqabileyo, enomhlaza eyenzeka kwi-cerebellum (isiqu sobuchopho), njengoko ixhaphake kakhulu ebantwaneni kunabantu abadala. I-tumor ikhula ngokukhawuleza kwaye inokusasazeka kwezinye iindawo zobuchopho kunye nentambo yomgogodla. Iimpawu ze-medulloblastoma ziquka intloko, isiyezi, isicaphucaphu kunye nokuhlanza, ukudinwa, imiba yokulinganisela, utshintsho kwimbono, ukuhamba ubunzima, intlungu emva, iingxaki zomchamo okanye izibilini. Izizathu ze-medulloblastoma aziqondwa ngokupheleleyo, kodwa ukuguqulwa kofuzo kwimizila efana ne-BRCA1 kunye ne-BRCA2 inokudlala indima. Ukhetho lonyango lwe-medulloblastoma lubandakanya utyando, unyango lwemitha, kunye nechemotherapy, elungiselelwe imeko ethile yomntu. I-prognosis kunye nesantya sokusinda kwabantu abadala abane-medulloblastoma yahlukile kweyabantwana. Inqanaba leminyaka emi-5 lokusinda kwi-medulloblastoma lingaphezulu kwe-70%. Ubomi emva kwe-medulloblastoma bufuna ukujongwa ngokusondeleyo kunye nokunakekelwa okulandelwayo

KwiMedulloblastoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu wesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Medulloblastoma ingaba ibalulekile into yokutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngeMedulloblastoma?

Umzekelo ingaba inomsebenzi ukuba imifuno yaseNew Zealand isipinatshi ityiwa kakhulu xa ithelekiswa neJerusalem Artichoke? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kuneRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut ngaphezu kweChestnut yaseYurophu kunye neentyatyambo ezifana neBroad Bean phezu kweHyacinth Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Medulloblastoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwiMedulloblastoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo i-Pummelo iqulethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Isoliquiritigenin, i-Apigenin, i-Lycopene. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Quercetin, i-Ellagic Acid, i-Curcumin, i-Isoliquiritigenin, i-Formononetin kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Medulloblastoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seMedulloblastoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiMedulloblastoma?

Isondlo somntu kumhlaza onje ngeMedulloblastoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Medulloblastoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMedulloblastoma

Zonke ii-cancer ezifana ne-Medulloblastoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Medulloblastoma. Iindlela ze-Biochemical ezifana nokulungiswa kwe-DNA, i-Angiogenesis, i-Oncogenic Histone Methylation, i-Epithelial ukuya kwi-Mesenchymal Transition iyingxenye yenkcazo yesignesha ye-Medulloblastoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Medulloblastoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali ezihambelanayo kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Medulloblastoma xa uthatha unyango lomhlaza iTemozolomide, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-PTCH1, i-TERT, i-DDX3X, i-KMT2D kunye ne-CTNNB1 zezona ziphezulu iigenes ezixeliweyo ze-Medulloblastoma. I-PTCH1 ixelwe kwi-6.3% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-TERT ixelwe kwi-6.2%. I-data edityanisiweyo yesigulane igubungela iminyaka yobudala ukusuka ku-1 ukuya kuma-50. I-62.3 % yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeMedulloblastoma kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMedulloblastoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha imifuno NEW ZEALAND SPINACH okanye IJERUSALEM ARTICHOKE?

Imifuno yaseNew Zealand Isipinatshi iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Isoliquiritigenin, i-Apigenin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Growth Factor Signaling, i-Hypoxia, i-NFKB yokuSayina kunye ne-Focal Adhesion kunye nabanye. Isipinatshi saseNew Zealand sinconywa kwi-Medulloblastoma xa unyango lomhlaza oluqhubekayo yiTemozolomide. Oku kungenxa yokuba Isipinatshi saseNew Zealand siguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zikhuthaze umphumo weTemozolomide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Artichoke yaseJerusalem yi-Curcumin, i-Isoliquiritigenin, i-Apigenin, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-TGFB Signaling kunye nezinye. I-Jerusalem Artichoke ayikhuthazwa nge-Medulloblastoma xa unyango lomhlaza oluqhubekayo yi-Temozolomide kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IMIFUNO EENTSHA ZEALAND IYACEBISWA NGAPHEZU KWEYERUSALEM ARTICHOKE NGE-Medulloblastoma KUNYE NONYANGO I-Temozolomide.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Ellagic Acid, i-Curcumin, i-Isoliquiritigenin, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-NFKB Signaling, i-Focal Adhesion kunye ne-Oxidative Stress kunye nabanye. I-Red Raspberry inconywa kwi-Medulloblastoma xa unyango oluqhubekayo lomhlaza luyiTemozolomide. Oku kungenxa yokuba i-Red Raspberry iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo weTemozolomide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Quercetin, i-Curcumin, i-Isoliquiritigenin, i-Apigenin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. IPummelo ayikhuthazwa kwiMedulloblastoma xa unyango lomhlaza oluqhubekayo yiTemozolomide kuba luguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU ESIQINISEKISO SESIQINISEKISO PHEZU KWE-PUMMELO YE-Medulloblastoma KUNYE NONYANGO I-Temozolomide.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Isoliquiritigenin, i-Apigenin, i-Lycopene, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, Ukulungiswa kwe-DNA, i-NFKB yokuSayina kunye ne-Focal Adhesion kunye nabanye. I-Butternut iyacetyiswa kwi-Medulloblastoma xa unyango lomhlaza oluqhubekayo yi-Temozolomide. Oku kungenxa yokuba i-Butternut iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zikhuthaze umphumo weTemozolomide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Curcumin, i-Isoliquiritigenin, i-Apigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-TGFB Signaling kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa nge-Medulloblastoma xa unyango lomhlaza oluqhubekayo i-Temozolomide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT IYANCEBISWA NGAPHEZU KWE-EUROPEY CHESTNUT NGE-Medulloblastoma KUNYE NONYANGO I-Temozolomide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Medulloblastoma okanye imbali yosapho "Yintoni endifanele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenziwa malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nesignesha yendlela - ukhetho lokutya kunye nezongezelelo kufuneka lube lomntu.

Khetha iVegetable GIANT BUTTERBUR or OSTRICH FERN?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-JAK-STAT Signaling, i-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Medulloblastoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno Inciniba iFern yiCurcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics, i-WNT Beta Catenin Signaling kunye ne-Stem Cell Signaling kunye nabanye. Inciniba iFern ayikhuthazwa xa umngcipheko we-Medulloblastoma xa umngcipheko wemfuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA PHEZU KWE-OSTRICH FERN NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo seNANCE okanye UMdiliya wasehlotyeni?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Betulinic Acid, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-JAK-STAT Signaling, i-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Nance icetyiswa kumngcipheko we-Medulloblastoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zasehlotyeni zeDiliya yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics, i-WNT Beta Catenin Signaling kunye ne-Stem Cell Signaling kunye nabanye. Umdiliya wasehlotyeni awukhuthazwa xa umngcipheko weMedulloblastoma xa umngcipheko wemfuzo uhambelana neCTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE IYAKUCEBISWA NGAPHEZU KOMdiliya wasehlotyeni we-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha Nut CHIA okanye JAPANESE WALNUT?

I-Chia iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-RAS-RAF Signaling, i-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Chia icetyiswa kumngcipheko we-Medulloblastoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba i-Chia yonyusa ezo ndlela zebhayoloji ezichasana nabaqhubi abatyikityayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Walnut yaseJapan yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics, i-WNT Beta Catenin Signaling kunye ne-Stem Cell Signaling kunye nabanye. IWalnut yaseJapan ayikhuthazwa xa umngcipheko we-Medulloblastoma xa umngcipheko wemfuzo unxulunyaniswa ne-CTNNB1 kuba yonyusa iindlela zokutyikitya.

I-CHIA ICEBISWA NGE-WALNUT YASEJAPANE NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neMedulloblastoma. Izigulana ze-Medulloblastoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Medulloblastoma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana nesipinatshi saseNew Zealand kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwiMedulloblastoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Ubuchopho Cptac 2020
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• I-Retinol inciphisa amanqanaba eprotheyini ye-beta-catenin kwimigca yeseli ye-retinoic acid-resistant colon cancer.
• https://www.cancer.gov/rare-brain-spine-tumor/tumors/medulloblastoma
• Eibl T et al, Ukuguga (Albany NY), 2021
• https://my.clevelandclinic.org/health/diseases/22591-medulloblastoma
• https://www.cancer.gov/rare-brain-spine-tumor/tumors/medulloblastoma#:~:text=Medulloblastoma%20Prognosis,how%20they%20respond%20to%20treatment