Ukutya kweMedullary Thyroid Cancer!

intshayelelo

Ukutya kweMedullary Thyroid Cancer kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Umhlaza we-Medullary thyroid luhlobo olunqabileyo lomhlaza wegilo oluphuma kwiiseli ze-parafollicular C zedlala lengqula. I-Calcitonin luphawu oluphambili olusetyenziselwa ukuxilongwa kunye nokubeka iliso kumhlaza we-medullary thyroid, njengoko amanqanaba aphezulu ahlala ebonwa kubantu abachaphazelekayo. Amazinga okusinda kunye neziphumo zonyango kumhlaza we-medullary thyroid ziyahluka ngokuxhomekeke kwizinto ezifana nenqanaba kunye nokusasazeka kwesi sifo. Kubalulekile ukuba uqaphele iimpawu eziqhelekileyo ezinxulumene nomhlaza we-medullary thyroid, ezifana ne-nodule ye-thyroid, i-hoarseness, kunye nokutshintsha kumanqanaba e-calcium. Izikhokelo zonyango zinokubonelela ngexabiso elixabisekileyo kulawulo kunye nezicwangciso zonyango lwe-medullary thyroid cancer, ukuqinisekisa ukuba izigulane zifumana ukhathalelo olungcono kakhulu. I-Pathology ichaza iimpawu kunye neempawu zeeseli zomhlaza we-medullary thyroid, ukunceda abaqeqeshi bezempilo ukuba benze uxilongo oluchanekileyo. Imiba yemfuza nayo idlala indima kumhlaza we-medullary thyroid, kwaye utshintsho oluthile lunokunyusa umngcipheko wokuba nomhlaza. Ulingo lwezonyango lunokubonelela ngamathuba okuba izigulana zifikelele kwiindlela ezintsha zonyango zomhlaza we-medullary thyroid kunye negalelo ekuqhubeleni phambili kolwazi lwezonyango. Hlala unolwazi malunga neentlobo ezahlukeneyo zomhlaza we-medullary thyroid kunye neendlela zonyango ezikhoyo, kubandakanywa ichemotherapy kunye nolunye unyango olujoliswe kuyo. Ngolawulo olufanelekileyo kunye nokungenelela ngexesha elifanelekileyo, umhlaza we-medullary thyroid unokulawulwa ngokufanelekileyo kwaye impembelelo yawo iyancipha.

KwiMedullary Thyroid Cancer ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neMedullary Thyroid Cancer ingaba inomsebenzi ukuba kukutya ntoni na endikutyayo kwaye ndingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngeMedullary Thyroid Cancer?

Umzekelo ingaba inomsebenzi ukuba i-Endive yemifuno ityiwa kakhulu xa ithelekiswa ne-Sunburst Squash (i-pattypan Squash)? Ngaba kuyawenza umahluko ukuba isiqhamo iAlaska Blueberry sikhethwa ngaphezu kweRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neCashew Nut phezu kweWalnut yaseJapan kunye nezityalo ezifana neCowpea ngaphezu kweGram Bean. Kwaye ukuba into endiyityayo ibalulekile - ke umntu uchonga njani ukutya okucetyiswayo kwiMedullary Thyroid Cancer kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiMedullary Thyroid Cancer!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo i-Alaska Blueberry iqulethe izithako ezisebenzayo i-Curcumin, i-Lupeol, i-Protocatechuic Acid, i-Formononetin, i-Daidzein. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Curcumin, i-Quercetin, i-Vitamin C, i-Ellagic Acid, i-Lupeol kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Medullary Thyroid Cancer - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungayihoyi enye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seMedullary Thyroid Cancer.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiMedullary Thyroid Cancer?

Isondlo esilungiselelwe wena somhlaza ofana neMedullary Thyroid Cancer siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubungcali kwi-Medullary Thyroid Cancer biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle indlela unyango lomhlaza olusebenza ngayo kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMedullary Thyroid Cancer

Yonke imihlaza efana neMedullary Thyroid Cancer inokuphawulwa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya zeMedullary Thyroid Cancer. Iindlela ze-Biochemical ezifana ne-Hypoxia, i-Oxidative Stress, i-Growth Factor Signaling, i-Chromatin Remodeling iyingxenye yenkcazo yesignesha ye-Medullary Thyroid Cancer. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Medullary Thyroid Cancer kufuneka luthathele ingqalelo utyikityo lweendlela zebhayoloji kwisigulane ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezelelo zicetyiswa kwiMedullary Thyroid Cancer xa uthatha unyango lomhlaza i-Axitinib, kwaye ezinye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-RET, i-KMT2A, i-EPHA3, i-ARID1A kunye ne-BLM zezona zixeliweyo zemfuza zeMedullary Thyroid Cancer. I-RET ixelwe kwi-16.7% yezigulane ezimele kuzo zonke iimvavanyo zeklinikhi. Kwaye i-KMT2A ixelwe kwi-5.6%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-55.3% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yoMhlaza weMedullary Thyroid kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMedullary Thyroid Cancer

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable ENDIVE okanye SUNBURST SQUASH (PATTYPAN SQUASH)?

I-Endive yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Vitamin C, i-Lupeol, i-Protocatechuic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-MYC Signaling kunye ne-Oxidative Stress kunye nezinye. I-Endive iyacetyiswa kwi-Medullary Thyroid Cancer xa unyango lomhlaza oluqhubekayo yi-Axitinib. Oku kungenxa yokuba i-Endive iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Axitinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Sunburst Squash (i-pattypan Squash) yi-Curcumin, i-Lupeol, i-Protocatechuic Acid, i-Formononetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Sunburst Squash (i-pattypan Squash) ayikhuthazwa kwi-Medullary Thyroid Cancer xa unyango lomhlaza oluqhubekayo luyi-Axitinib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQINISEKISO SESIQINISEKISO SOKUGQIBISWA NGE-SUNBURST SQUASH (i-PATTYPAN SQUASH) YOMhlaza we-Medullary Thyroid KUNYE NONYANGO i-Axitinib.

Khetha iSiqhamo RED RASPBERRY okanye i-ALASKA BLUEBERRY?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Vitamin C, i-Ellagic Acid, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, EPHRIN Signaling, i-MYC Signaling kunye ne-Oxidative Stress kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Medullary Thyroid Cancer xa unyango oluqhubekayo lomhlaza yi-Axitinib. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Axitinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo ze-Alaska Blueberry yi-Curcumin, i-Lupeol, i-Protocatechuic Acid, i-Formononetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Alaska Blueberry ayikhuthazwa kwi-Medullary Thyroid Cancer xa unyango lomhlaza oluqhubekayo yi-Axitinib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

ISIQHAMO ERED RASPBERRY KUNCEBISWA NGAPHEZU KWE-ALASKA BLUEBERRY YE-Medullary Thyroid Cancer KUNYE NONYANGO i-Axitinib.

Khetha i- Nut CASHEW NUT okanye WALNUT YASEJAPANE?

I-Cashew Nut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Vitamin C, i-Lupeol, i-Protocatechuic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling kunye ne-Oxidative Stress kunye nezinye. I-Cashew Nut icetyiswa kwi-Medullary Thyroid Cancer xa unyango oluqhubekayo lomhlaza yi-Axitinib. Oku kungenxa yokuba i-Cashew Nut iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Axitinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Walnut yaseJapan i-curcumin, i-Ellagic Acid, i-Lupeol, i-Protocatechuic Acid, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. IWalnut yaseJapan ayikhuthazwa kwiMedullary Thyroid Cancer xa unyango lomhlaza oluqhubekayo yi-Axitinib kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CASHEW UT IYAYINGCEBISWA NGAPHEZU KWEWALNUT YASEJAPANE NGENXA YE-Medullary Thyroid Cancer KUNYE NONYANGO I-Axitinib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwayo ngabantu abasengozini yemfuzo yeMedullary Thyroid Cancer okanye imbali yentsapho ithi "Yintoni ekufuneka Ndiyitye Ngokwahlukileyo Ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR okanye ikhaphetshu EMNYAMA?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-EPHRIN Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Medullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa nayo yi-ARID1A. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Black Cabbage yi-Curcumin, i-Apigenin, i-Myricetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuSayina kwe-MAPK, ukulungiswa kwe-DNA kunye ne-WNT Beta Catenin Signaling kunye nabanye. Ikhaphetshu elimnyama ayikhuthazwa xa umngcipheko weMedullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa nayo yi-ARID1A kuba yonyusa iindlela zokutyikitywa kwayo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA PHEZU KWEKHABHUJI EMNYAMA KU-ARID1A UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Myricetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-EPHRIN Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. UNance ucetyiswa kumngcipheko we-Medullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa nayo yi-ARID1A. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Curcumin, i-Apigenin, i-Quercetin, i-Lycopene, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebiochemical ezifana neWNT Beta Catenin Signaling kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko weMedullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa ne-ARID1A kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE IYACEBISWA NGAPHEZU KWE-PUMMELO KU-ARID1A GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-RAS-RAF yokuSayina kunye ne-EPHRIN yokuSayina kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko weMedullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa nayo yi-ARID1A. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Curcumin, i-Apigenin, i-Ellagic Acid, i-Myricetin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-WNT Beta Catenin Signaling kunye nezinye. I-Chestnut ayikhuthazwa xa umngcipheko we-Medullary Thyroid Cancer xa ingozi yemfuzo eyayanyaniswa nayo yi-ARID1A kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYAYINGCEBISWA NGAPHEZU KWE-CHESTNUT NGE-ARID1A UMNGCIPHEKO WEMFUZO YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neMedullary Thyroid Cancer. Izigulana zoMhlaza we-Medullary Thyroid kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana noMhlaza we-Medullary Thyroid, nganye inemfuza eyahlukileyo yethumba kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Endive kuqulethe i-bioactives eyahlukeneyo ngokwemiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Medullary Thyroid Cancer?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Delphinidin inqanda i-angiogenesis ngokunyanzeliswa kwe-HIF-1α kunye ne-VEGF ibonakaliso kwiiseli zomhlaza wamaphaphu ze-A549.
• I-Curcumin inqanda ukukhula ngendlela ye-Wnt / β-catenin kwiiseli zomhlaza wemiphunga ezingezizo ezincinci.
• Isiphumo sokuthintela i-Hibiscus protocatechuic acid ekukhuthazeni ithumba kwisikhumba sempuku.
• I-Vitamin C iphucula ukuguqulwa kwe-epigenetic eyenziwa yi-5-azacytidine kunye nokubanjwa komjikelo weseli kwi-hepatocellular carcinoma celllines HLE kunye ne-Huh7.
• I-Retinol inciphisa amanqanaba eprotheyini ye-beta-catenin kwimigca yeseli ye-retinoic acid-resistant colon cancer.
• I-β-Sitosterol kunye neGemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity ngokuModulating i-Apoptosis kunye ne-Inhibiting Epithelial-Mesenchymal Transition ngo-Deactivating Akt / GSK-3β Signaling.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• I-asidi ye-Gallic ixhokonxa umonakalo we-DNA kwaye icinezela i-DNA yokulungisa i-gene expression kwi-prostate cancer yomntu iiseli ze-PC-3.