Ukutya kweMantle Cell Lymphoma!

intshayelelo

Ukutya kweMantle Cell Lymphoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Mantle cell lymphoma (MCL) luhlobo lomhlaza oluchaphazela inkqubo ye-lymphatic. Ikhowudi yonyango echanekileyo usebenzisa ikhowudi ye-ICD-10 iqinisekisa amaxwebhu afanelekileyo kwiimeko ze-Mantle cell lymphoma. Ulwandlalo lwePathology ludlala indima ebalulekileyo ekuqondeni iimpawu ze-MCL. Iinketho zonyango ze-MCL zinokubandakanya iindlela ezahlukeneyo ezifana nonyango olujoliswe kuyo, ichemotherapy, i-immunotherapy, i-stem cell transplantation, kunye nonyango lwemitha. I-prognosis ye-MCL iyahluka ngokuxhomekeke kwizinto ezininzi, kubandakanywa nenqanaba kunye ne-subtype ethile yesifo. Amazinga okusinda kwe-MCL aphuculwe kwiminyaka edlulileyo ngenxa yenkqubela phambili yonyango kunye nokunakekelwa kwenkxaso. Kubalulekile ukunikela ingqalelo kwiimpawu ezinokuthi ziquka i-lymph nodes eyandisiweyo, ukudinwa, ukubila ebusuku, kunye nokunciphisa umzimba. Ukwahlukana kwe-blastoid ye-MCL luhlobo olunobundlobongela olufuna unyango olukhawulezileyo nolunzulu. Amanqaku ahlukeneyo anceda ekuxilongeni nasekubekeni iliso kwi-MCL, enika ulwazi malunga nokuqhubela phambili kwesifo kunye nokuphendula kunyango. Iinguqu zemfuza ziyaziwa ngokuba negalelo kuphuhliso lwe-MCL. Ulingo lwezonyango luhlala luphanda iindlela ezintsha zonyango kunye nezicwangciso ze-MCL. Ukuqonda imingcipheko enxulumene ne-MCL kunye nokuhlala unolwazi malunga nophuhliso lwamva nje lophando lunokunceda kulawulo olusebenzayo kunye nokwenza izigqibo ngonyango. Ngokusebenzisana ngokusondeleyo nabasebenzi bezempilo, abantu abane-MCL banokufikelela kwiiprothokholi zonyango zamva nje kwaye baphucule amathuba abo eziphumo eziyimpumelelo.

KwiMantle Cell Lymphoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neMantle Cell Lymphoma ingaba ibalulekile na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngeMantle Cell Lymphoma?

Umzekelo ingaba inomsebenzi ukuba iCauliflower yemifuno ityiwa kakhulu xa ithelekiswa neArrowroot? Ngaba kuyawenza umahluko ukuba isiqhamo se-Sea-buckthornberry sikhethwa ngaphezu kwe-Red Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut ngaphezu kweCashew Nut kunye nezityalo ezifana neBroad Bean phezu kweLentils. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Mantle Cell Lymphoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiMantle Cell Lymphoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo, i-Sea-buckthornberry iqukethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Isoliquiritigenin. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Isoliquiritigenin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Mantle Cell Lymphoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seMantle Cell Lymphoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiMantle Cell Lymphoma?

Isondlo esilungiselelwe wena somhlaza njengeMantle Cell Lymphoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubungcali kwi-Mantle Cell Lymphoma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMantle Cell Lymphoma

Zonke ii-cancer ezifana ne-Mantle Cell Lymphoma zinokuphawulwa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya zeMantle Cell Lymphoma. Iindlela ze-Biochemical ezifana ne-Vitamin Metabolism, i-Cell Cycle Checkpoints, i-Cell Cycle, i-Oncogenic Histone Methylation iyingxenye yenkcazo yesiginesha ye-Mantle Cell Lymphoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Mantle Cell Lymphoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali enxulumene nesigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Mantle Cell Lymphoma xa uthatha unyango lomhlaza i-Cyclophosphamide, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-CDC27, FAT1, RYR3, ASH1L kunye ne-KMT2C zezona ziphezulu iigenes ezixeliweyo zeMantle Cell Lymphoma. I-CDC27 ixelwe kwi-11.4% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-FAT1 ichazwe kwi-5.9%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-72.7% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeMantle Cell Lymphoma kunye negenetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMantle Cell Lymphoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CAULIFLOWER okanye i-ARROWROOT?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Isoliquiritigenin, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ii-Checkpoints ze-Cell Cycle, i-NFKB Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. ICauliflower iyacetyiswa ngeMantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo iCyclophosphamide. Oku kungenxa yokuba i-Cauliflower ilungisa ezo ndlela ze-biochemical eziye zachazwa ngokwenzululwazi ukuze zikhuthaze isiphumo se-Cyclophosphamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Arrowroot yi-Quercetin, i-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, ukulungiswa kwe-DNA kunye ne-Amino Acid Metabolism kunye nabanye. I-Arrowroot ayikhuthazwa kwi-Mantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CAULIFLOWER YOMFUNO INCEBISWA NGAPHEZU KWE-ARROWROOT YE-Mantle Cell Lymphoma KUNYE NONYANGO I-Cyclophosphamide.

Khetha iSiqhamo RED RASPBERRY okanye SEA-BUCKTHORNBERRY?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ii-Checkpoints ze-Cell Cycle, i-NFKB Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Mantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide. Oku kungenxa yokuba i-Red Raspberry iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo we-Cyclophosphamide.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo se-Sea-buckthornberry yi-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, ukulungiswa kwe-DNA kunye ne-Amino Acid Metabolism kunye nabanye. I-Sea-buckthornberry ayikhuthazwa kwi-Mantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU IRASPBHARI IYACEBISWA NGAPHEZU KWE-SEA-BUCKTHORNBERRY YEMantle Cell Lymphoma KUNYE NONYANGO ICyclophosphamide.

Khetha i-Nutt BUTTERNUT okanye i-CASHEW NUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, ukulungiswa kwe-DNA, i-Amino Acid Metabolism kunye nokusinda kweSeli kunye nabanye. I-Butternut inconywa kwi-Mantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo i-Cyclophosphamide. Oku kungenxa yokuba iButternut ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCyclophosphamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Cashew Nut yi-Quercetin, i-Curcumin, i-Lupeol, i-Isoliquiritigenin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling kunye ne-NFKB Signaling kunye nabanye. I-Cashew Nut ayikhuthazwa kwi-Mantle Cell Lymphoma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungabi luncedo kakhulu.

IBHUTTERNUT IYAYINGCEBISWA NGAPHEZU KWE-CASHEW TUT YEMantle Cell Lymphoma KUNYE NONYANGO I-Cyclophosphamide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuza ye-Mantle Cell Lymphoma okanye imbali yosapho "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or MALABAR SPINACH?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-EPHRIN Signaling, i-MYC Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Mantle Cell Lymphoma xa ingozi yemfuzo eyayanyaniswa nayo yi-ASH1L. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno i-Malabar Spinach yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana neCell Cycle Checkpoints kunye nokulungiswa kweDNA kunye nezinye. I-Malabar Spinach ayikhuthazwa xa umngcipheko we-Mantle Cell Lymphoma xa umngcipheko wezofuzo uhambelana ne-ASH1L kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA PHEZU KWE-MALABAR SPINACH NGE-ASH1L YOMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-EPHRIN Signaling, i-MYC Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Nance icetyiswa kumngcipheko we-Mantle Cell Lymphoma xa ingozi yemfuzo eyayanyaniswa nayo yi-ASH1L. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana neCell Cycle Checkpoints kunye nokulungiswa kweDNA kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko weMantle Cell Lymphoma xa umngcipheko wezofuzo unxulunyaniswa ne-ASH1L kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO NGE-ASH1L GENETIC RISK YOMHLAZA.

Khetha i-Nutt EMNYAMA WALNUT okanye i-CHESTNUT?

I-Walnut emnyama iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-MYC Signaling, i-Apoptosis kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. IWalnut emnyama icetyiswa kumngcipheko weMantle Cell Lymphoma xa umngcipheko wemfuzo onxulumeneyo yi-ASH1L. Oku kungenxa yokuba iWalnut Emnyama yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko weMantle Cell Lymphoma xa umngcipheko wezofuzo unxulunyaniswa ne-ASH1L kuba yonyusa iindlela zokutyikitya kuyo.

IWALNUT EMNYAMA KUCEBISWA NGAPHEZU KWE-CHESTNUT NGE-ASH1L YOMNGCIPHEKO WEFUZO YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neMantle Cell Lymphoma. Izigulana zeMantle Cell Lymphoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana neMantle Cell Lymphoma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye ulwahlulo lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neCauliflower kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon yesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwiMantle Cell Lymphoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
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• I-Vitamin C iphucula ukuguqulwa kwe-epigenetic eyenziwa yi-5-azacytidine kunye nokubanjwa komjikelo weseli kwi-hepatocellular carcinoma celllines HLE kunye ne-Huh7.
• I-Brassinin inqanda indlela yokubonisa i-STAT3 ngokumodareyithwa kwe-PIAS-3 kunye ne-SOCS-3 intetho kwaye inike amandla i-xenograft yomhlaza wemiphunga yabantu kwiimpuku ezinqunu ukuya kwi-paclitaxel.
• I-Lycopene inqanda ukuSebenza kwe-Epidermal Growth Factor Receptor kunye nokubonakaliswa kwe-Cyclooxygenase-2 kwiiseli zeCancer Gastric.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• I-α-pinene ilawula i-miR-221 kwaye yenza i-G₂/ Isigaba se-M sokubanjwa komjikelo weseli kwiiseli ze-hepatocellular carcinoma.
• I-asidi ye-Gallic ixhokonxa umonakalo we-DNA kwaye icinezela i-DNA yokulungisa i-gene expression kwi-prostate cancer yomntu iiseli ze-PC-3.