Ukutya kwentloko kunye neNtamo Neuroendocrine Carcinoma!

intshayelelo

Ukutya kwentloko kunye neNtamo I-Neuroendocrine Carcinoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Kwintloko kunye neNtamo Neuroendocrine Carcinoma ingaba ayinamsebenzi ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje ngentloko kunye neNeuroendocrine Carcinoma ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyileyo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo kwanele ukuba umhlaza onje ngeNtloko kunye neNtamo Neuroendocrine Carcinoma?

Umzekelo ingaba iyabaluleka na into yokuba imifuno iBrussels Sprouts ityiwa kakhulu xa ithelekiswa neShallot? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyakhethwa kuneSoursop? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neWalnut emnyama phezu kwembewu yethanga kunye nemifuno efana ne-Pea enamehlo aMnyama ngaphezu kwe-Common Bean. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwiNtloko kunye neNtamo Neuroendocrine Carcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwiNtloko kunye neNtamo Neuroendocrine Carcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo iCurcumin, i-Apigenin, iCatechol, iLupeol, iDaidzein. Kwaye i-Soursop iqulethe izithako ezisebenzayo Apigenin, Curcumin, Emodin, Catechol, Daidzein kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwiNtloko kunye neNtamo I-Neuroendocrine Carcinoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seNtloko kunye neNtamo Neuroendocrine Carcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiNtloko kunye neNtamo Neuroendocrine Carcinoma?

Izondlo zomntu zomhlaza ezifana neNtloko kunye neNtamo I-Neuroendocrine Carcinoma ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwiNtloko kunye neNeuroendocrine Carcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene noko unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza njengentloko kunye neNtamo Neuroendocrine Carcinoma

Zonke ii-cancer ezifana neNtloko kunye neNtamo I-Neuroendocrine Carcinoma inokubonakaliswa ngeseti ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya zeNtloko kunye neNtamo Neuroendocrine Carcinoma. Iindlela ze-Biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, i-Growth Factor Signaling, i-Oncogenic Histone Methylation, i-Chromatin Remodeling iyingxenye yenkcazo yesignesha yeNtloko kunye neNtamo ye-Neuroendocrine Carcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiNtloko kunye neNtamo I-Neuroendocrine Carcinoma kufuneka ithathelwe ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezelelo zicetyiswa kwiNtloko kunye neNtamo Neuroendocrine Carcinoma xa uthatha unyango lomhlaza iCapecitabine, kwaye ezinye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-ERBB4, i-FGFR1, i-INPPL1, i-IRS1 kunye ne-NSD1 ziluhlu oluphezulu lwezakhi zofuzo ezichazwe kwiNtloko kunye neNtamo ye-Neuroendocrine Carcinoma. I-ERBB4 ixelwe kwi-100.0% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-FGFR1 ichazwe kwi-100.0%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-66.7% yedatha yesigulane ichongwa njengamadoda. Intloko kunye neNtamo I-Neuroendocrine Carcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeNtloko kunye neNtamo Neuroendocrine Carcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable BRUSSEL sprouts okanye SHALLOT?

Imifuno ye-Brussel Sprouts iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Catechol, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Brussel Sprouts inconywa kwiNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa unyango oluqhubekayo lomhlaza yi-Capecitabine. Oku kungenxa yokuba i-Brussel Sprouts ilungisa ezo ndlela zebhayokhemikhali ekuye kwaxelwa ngazo ngokwenzululwazi ukwazisa ifuthe le-Capecitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Shallot yemifuno yi-Apigenin, i-Curcumin, i-Catechol, i-Daidzein, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Shallot ayikhuthazwa kwiNtloko kunye neNtamo I-Neuroendocrine Carcinoma xa unyango lomhlaza oluqhubekayo yi-Capecitabine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IZIPHUMA ZEBRUSSEL ZEMIFUNO IYAKUCEBISWA NGAPHEZU KWE-SHALLOT YENtloko neNtamo I-Neuroendocrine Carcinoma KUNYE NONYANGO I-Capecitabine.

Khetha iSiqhamo SOURSOP okanye iPUMMELO?

I-Fruit Soursop iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Emodin, i-Catechol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Soursop inconywa kwiNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa unyango oluqhubekayo lomhlaza yi-Capecitabine. Oku kungenxa yokuba iSoursop ilungisa ezo ndlela zebhayokhemikhali ezixelwe ngokwenzululwazi ukwazisa isiphumo seCapecitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yiCurcumin, i-Apigenin, iCatechol, iLupeol, iDaidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. IPummelo ayikhuthazwa kwiNtloko kunye neNtamo I-Neuroendocrine Carcinoma xa unyango lomhlaza oluqhubekayo yi-Capecitabine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

ISIQHAMO SOURSOP IYAKUNIKEZWA NGAPHEZU KWE-PUMMELO YENtloko neNtamo Neuroendocrine Carcinoma KUNYE NONYANGO ICapecitabine.

Khetha i Nut WALNUT EMNYAMA okanye IMBEWU YAMATHANGA?

I-Walnut emnyama iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Catechol, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Walnut emnyama inconywa kwiNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa unyango oluqhubekayo lomhlaza yi-Capecitabine. Oku kungenxa yokuba iWalnut emnyama iguqula ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCapecitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiMbewu yePumpkin yi-Beta-sitosterol, i-Oleic Acid, i-Linolenic Acid, i-Stigmasterol, i-Salicylic Acid. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. Imbewu yethanga ayikhuthazwa kwiNtloko kunye neNtamo I-Neuroendocrine Carcinoma xa unyango lomhlaza oluqhubekayo yi-Capecitabine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

IWALNUT EMNYAMA KUNCEBISWA NGAPHEZU KWEMBEWU YAMATHANGO KWINtloko neNtamo I-Neuroendocrine Carcinoma KUNYE NONYANGO I-Capecitabine.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza yeNtloko kunye neNtamo ye-Neuroendocrine Carcinoma okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or SPINACH?

I-Vegetable Giant Butterbur iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lycopene, i-Myricetin, i-Delphinidin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-Insulin Signaling, i-RAS-RAF yokuSayina kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Giant Butterbur icetyiswa kumngcipheko weNtloko kunye neNtamo Neuroendocrine Carcinoma xa umngcipheko wemfuzo ohambelana ne-ERBB4. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno Isipinashi yi-Curcumin, i-Apigenin, i-Quercetin, i-Myricetin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Histone Methylation kunye ne-Insulin Signaling kunye nabanye. Isipinatshi asikhuthazwa xa umngcipheko weNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa umngcipheko wezofuzo uhambelana ne-ERBB4 kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA PHEZU KWESIPINCHI NGE-ERBB4 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye MALABAR PLUM?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Delphinidin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-Growth Factor Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Red Raspberry inconywa kumngcipheko weNtloko kunye neNtamo Neuroendocrine Carcinoma xa umngcipheko wemfuzo ohambelana ne-ERBB4. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwisiqhamo i-Malabar Plum yi-Curcumin, i-Apigenin, i-Lycopene, i-Myricetin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints kunye ne-Oncogenic Histone Methylation kunye nezinye. I-Malabar Plum ayikhuthazwa xa umngcipheko weNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa umngcipheko wezofuzo uhambelana ne-ERBB4 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO SESIQINISEKISO PHEZU KWE-MALABAR PLUM YE-ERBB4 GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lycopene, i-Myricetin, i-Delphinidin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-Insulin Signaling, i-RAS-RAF yokuSayina kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Hazelnut eqhelekileyo inconywa kumngcipheko weNtloko kunye neNtamo Neuroendocrine Carcinoma xa umngcipheko wemfuzo ohambelana ne-ERBB4. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Curcumin, i-Ellagic Acid, i-Apigenin, i-Quercetin, i-Myricetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Histone Methylation kunye ne-Insulin Signaling kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko weNtloko kunye neNtamo ye-Neuroendocrine Carcinoma xa umngcipheko wezofuzo uhambelana ne-ERBB4 kuba yonyusa iindlela zokutyikitya kuyo.

IHAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-EUROPE-CHESTNUT NGE-ERBB4 genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza njengeNtloko kunye neNtamo Neuroendocrine Carcinoma. Intloko kunye neNtamo Izigulane zeCarcinoma ze-Neuroendocrine kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana neNtloko kunye neNtamo Neuroendocrine Carcinoma, nganye inemfuza eyahlukileyo yethumba kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Brussels Sprouts kuqulethe iintlobo ngeentlobo ze-bioactives ngokwemiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwiNtloko kunye neNtamo Neuroendocrine Carcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Tmb Mskcc 2018
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