Iimbalasane
Iicancer zomntwana ezinjenge-leukemia ephathwa ngamayeza aphezulu anyukayo e-chemotherapy njenge-cyclophosphamides kunye ne-anthracyclines, ajongene nomngcipheko okhulayo wokuba nomhlaza olandelayo / wesibini. Umhlaza wesibini / wesibini kumaxhoba omhlaza wabantwana aqhelekile ukusebenza kwexesha elide kwechemotherapy.
Umhlaza wabantwana
Umhlaza wabantwana wenzeka ebantwaneni, kulutsha nakubantu abadala. Owona mhlaza uxhaphakileyo ebantwaneni yileukemia, umhlaza wegazi. Ezinye iintlobo zomhlaza ezifana ne-lymphoma, i-brain tumors, i-sarcomas kunye nezinye izicubu eziqinileyo nazo zingenzeka. Enkosi kunyango oluphuculweyo, kukho ngaphezulu kwe-80% yabantwana abasinde kumhlaza e-US. Unyango luxhomekeke kuhlobo lomhlaza kodwa lunokubandakanya uqhaqho, chemotherapy, unyango lweradiation kunye nakutshanje nkqu nonyango lwamajoni omzimba. Nangona kunjalo, ngokweNational Pediatric Cancer Foundation, baqikelela ukuba ngaphezulu kwe-95% yabantwana abasinde kumhlaza baya kuba nomcimbi obalulekileyo onxulumene nempilo xa beneminyaka engama-45 ubudala, enokuba sisiphumo sonyango lwangaphambili lomhlaza.https://nationalpcf.org/facts-about-childhood-cancer/).
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
Umhlaza wesibini kumaxhoba omhlaza wobuntwana
Ngobukho benani elikhulu labasindileyo bomhlaza, abaphandi abavela kwiYunivesithi yaseMinnesota Medical School bavavanya umbutho wabasindileyo bomhlaza wabantwana abaphathwa nge-chemotherapy kunye neziganeko zesilonda esibuhlungu esilandelayo (SMN) njengenxalenye yesifundo somntu osindileyo somhlaza (I-Turcotte LM okqhubekayo, J Clin Oncol., 2019). Bavavanya ii-SMNs kumaxhoba aqala ukufumanisa ukuba anomdlavuza xa ayengaphantsi kweminyaka engama-21 ubudala, phakathi ko-1970-1999. Iinkcukacha eziphambili zabemi abafundayo kunye neziphumo zohlalutyo lwabo zezi:
- Iminyaka yama-Median ekufumanekeni yayiyiminyaka engama-7 kunye nobudala bokugqibela ekulandeleleni kwiminyaka engama-31.8.
- Bavavanya ngaphezulu kwabangama-20,000 XNUMX abasindileyo ebuntwaneni ababephathwe nge-chemotherapy kuphela, i-chemotherapy kunye nonyango lwe-radiation, unyango lwe-radiation kuphela okanye hayi.
- Abasindileyo ebuntwaneni abaphathwe nge-chemotherapy bodwa babenobungozi obungu-2.8 kumngcipheko we-SMN.
- Ireyithi yezehlo ze-SMN yayiphezulu kumaxhoba obuntwana anyangwa ngonyango lweplatinam. Ukongeza, iiarhente ze-alkylating (Umz. I-cyclophosphamide) kunye ne-anthracyclines (umzekelo. I-Doxorubicin), kwabakho ubudlelwane bempendulo yedosi obonwe phakathi kweedosi eziphezulu zezi chemotherapy kunye neziganeko eziphezulu zomhlaza wamabele.
Umngcipheko weSifo seCancer seBanga lesiBini kwiLeukemia okanye eSarcoma Survivors
Kolunye uhlalutyo lwangaphambili njengenxalenye yesifundo sokusinda komhlaza kubantwana esasibandakanya i-3,768 yabasetyhini abanomdlavuza wegazi okanye umhlaza wesarcoma Abasindileyo abanyangwe ngeedosi ezandayo ze-chemotherapy ezinjenge-cyclophosphamide okanye i-anthracyclines, kwafunyaniswa ukuba banxulunyaniswa kakhulu nomngcipheko wokuba nomhlaza webele wokuqala / wesibini wokuqala. Kwakukho u-5.3 fold kunye no-4.1 fold fold risk to develop Second / secondary cancer cancer in sarcoma and leukemia survivors ngokulandelanayo. (Henderson TO et al., J Klinikhi Oncol., 2016)
Umngcipheko weeCancer zoLusu eziSekondari kuBasindileyo beCarcer Survivors abaye bafumana i-Radiotherapy
Ngokweziphumo zolunye uphononongo olubizwa ngokuba yi-DCOG-LATER cohort study equka ama-5843 amaxhoba omhlaza wabantwana baseDatshi abafunyaniswe beneentlobo ezahlukeneyo zomhlaza. i cancer phakathi kuka-1963 no-2001, amaxhoba awayekhe anyangwa ngeradiotherapy ayenomngcipheko owongezelelweyo womhlaza wolusu wesibini. Oku kwakhona kuxhomekeke kubungakanani bendawo yesikhumba evezwe ngexesha lonyango. (Jop C Teepen okqhubekayo, J Natl Cancer Inst., 2019)
isiphelo
Isishwankathelo, abasindileyo kumhlaza wabantwana abaye banyangwa ngeedosi eziphezulu eziqokelelweyo zechemotherapy efana ne-cyclophosphamide okanye i-anthracyclines yomhlaza onjenge-leukemia bajongene nomngcipheko owonyukayo wokuba nomhlaza wesibini/wesibini (isiphumo sexesha elide sechemotherapy). Ngoko ke, uhlalutyo lwengozi-inzuzo ye umhlaza Unyango lwabantwana kunye nabantu abadala abancinci kufuneka bathande ukunyangwa ngokunciphisa iidosi ezongezelekayo zechemotherapy kunye nokuqwalaselwa kolunye okanye iindlela zonyango ezichongiweyo ezingaphezulu zokunciphisa umngcipheko wokukhula komhlaza oyingozi olandelayo kwixesha elizayo.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.