Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Ashitaba lijong tsa bona?

Lintlha-khōlō Tsa

Ashitaba e tsebahala haholo ka melemo ea eona ea bophelo bo botle mme e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Ashitaba bakeng sa bakuli ba mofetše li ipapisitse le lintlha tse ngata joalo ka sesupo sa mofets'e, chemotherapy, kalafo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Ashitaba e ka tsoela batho ba nang le Primary Penile Squamous Cell Carcinoma ba nang le Mitomycin, empa ho ka 'na ha se ke ha e-ba molemo ho bakuli ba fumanang Letrozole bakeng sa lefu la Primary Paget la letsoele. Ho feta moo, le hoja Ashitaba e ka thusa batho ba nang le lefutso la "ALK", e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea liphatsa tsa lefutso "ATM". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Ashitaba bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa tse kang mofuta oa kankere, mekhoa ea phekolo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Ashitaba ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / lisebelisoa tse kang Ashitaba ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Ashitaba lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho sebelisa Ashitaba haeba u na le liphatsa tsa lefutso tse amanang le mofetše oa ALK? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la ATM? Na ho molemo ho kenyelletsa Ashitaba lijong tsa hau haeba u fumanoa u e-na le lefu la Primary Paget la letsoele, kapa haeba tlhahlobo ea hau e le Primary Penile Squamous Cell Carcinoma? Ho feta moo, tšebeliso ea hau ea Ashitaba e lokela ho fetoloa joang haeba u ntse u fuoa phekolo ea Mitomycin kapa morero oa hau oa phekolo o tloha ho Mitomycin ho ea Letrozole? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Ashitaba ke ntho ea tlhaho, kahoo e lula e le molemo' kapa 'Ashitaba e matlafatsa sesole sa' mele 'ha e lekane bakeng sa khetho ea lijo / tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Ashitaba lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Ashitaba lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka liphello tse akaretsang tsa biochemical tsa metsoako eohle, u nahane ka lintlha tse kang mofuta oa kankere, phekolo e khethehileng eo u e etsang, liphatsa tsa lefutso. , le khetho ea bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, o kang Primary Penile Squamous Cell Carcinoma kapa Primary Paget lefu la letsoele, mekhoa ea phekolo e lokela ho hlophisoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le lilemo. bong.”

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofets'e ha u etsa qeto ka khetho ea lijo, joalo ka Ashitaba. Na kotsi ea liphatsa tsa lefutso bakeng sa mofets'e e bakoang ke phetoho ho ALK e na le litlamorao tse tšoanang tsa biochemical joalo ka phetoho ho ATM? Ho latela pono ea phepo e nepahetseng, na kotsi e amanang le Primary Penile Squamous Cell Carcinoma e lekana le lefu la Primary Paget la letsoele? Ho feta moo, na tlhokomelo ea lijo e lula e tšoana bakeng sa ba kenang Letrozole le ba fumanang Mitomycin? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Ashtaba - Tlatsetso ea Phepo

Tlatsetso ea Ashitaba e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyelletsa le Isobavachalcone, e 'ngoe le e' ngoe e teng ka maemo a fapaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo Lipid Metabolism, PI3K-AKT-MTOR Signaling le MAPK Signaling, e laolang likarolo tsa bohlokoa tsa mofets'e maemong a lisele, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ho fanoe ka tšusumetso ena ea likokoana-hloko, ho khetha li-supplement tse loketseng tse kang Ashitaba, feela kapa li kopane, e fetoha qeto ea bohlokoa tabeng ea phepo ea mofets'e. Ha u nahana ka ho sebelisa Ashitaba bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha le mekhoa ena e fapaneng. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Ashitaba ha se qeto ea lefats'e ka bophara e loketseng mafu a mofetše empa e hloka ho etsoa motho ka mong.

Ho Khetha Lisebelisoa tsa Ashitaba

Ho araba potso e reng 'Ke lokela ho qoba Ashita neng maemong a Kankere' ho thata hobane karabo e itšetlehile haholo ka motho ka mong - e mpa feela e le 'Ho itšetlehile!'. Joalo ka ha kalafo efe kapa efe ea mofets'e e kanna ea se sebetse ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Ashtaba e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le ntho leha e le efe ea ho kula kaofela li phetha karolo ea ho tseba hore na Ashitaba e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqeto tse joalo.

1. Na Li-Supplement tsa Ashitaba li tla thusa lefu la Primary Paget la Bakuli ba letsoele ba ntseng ba le tlas'a phekolo ea Letrozole?

Lefu la mantlha la letsoele la Paget le khetholloa ke liphetoho tse itseng tsa liphatsa tsa lefutso, e leng TTN, MUC22 le CCDC168, tse lebisang liphetohong tsa litsela tsa lik'hemik'hale, haholo-holo PI3K-AKT-MTOR Signaling. Katleho ea kalafo ea mofetše, joalo ka Letrozole, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Ka mohlala, tlatsetso ea Ashitaba, e amang PI3K-AKT-MTOR Signaling, e ka 'na ea se ke ea e-ba khetho e nepahetseng tabeng ea lefu la Primary Paget la sefuba ha le ntse le le Letrozole. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Li-Supplement tsa Ashitaba li tla thusa bakuli ba Primary Penile Squamous Cell Carcinoma ba ntseng ba le ka kalafo ea Mitomycin?

Penile Squamous Cell Carcinoma e khetholloa ka liphetoho tse khethehileng tsa lefutso, tse kang ABRAXAS1, PIK3CB le NUP93, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo Lipid Metabolism, Hematopoiesis le Inositol Phosphate Signaling. Katleho ea kalafo ea mofetše, joalo ka Mitomycin, e khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Ashitaba ke khetho e utloahalang bakeng sa ba nang le Primary Penile Squamous Cell Carcinoma ba nang le Mitomycin. Lebaka ke hobane Ashitaba e susumetsa litsela tse kang Lipid Metabolism, e ka thibelang mabaka a khanna Primary Penile Squamous Cell Carcinoma kapa ea rua molemo katlehong ea Mitomycin.

3. Na Lisebelisoa tsa Ashitaba li Sireletsehile Bakeng sa Batho ba Phelang ba nang le Phato ea ATM e Amanang le Kotsi ea Liphatsa tsa lefutso?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ATM o atisa ho kenyelletsoa liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea mofuta oa ATM e ama litsela kapa lits'ebetso tsa biochemical, joalo ka PI3K-AKT-MTOR Signaling le DNA Repair, tse amehang ka kotloloho kapa ka tsela e sa tobang ho khanna mofetše boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho ATM e amanang le kotsi e eketsehileng ea Chronic Myelomonocytic Leukemia, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tlatsetso ea Ashitaba. Lebaka ke hobane tlatsetso ea Ashitaba e susumetsa litsela tse kang PI3K-AKT-MTOR Signaling, e ka lebisang litlamorao tse mpe maemong a phetoho ea ATM le maemo a amanang le mofets'e.

4. Na li-Supplement tsa Ashitaba li Sireletsehile ho Batho ba Phelang ba nang le ALK Mutation Associated Genetic Kotsi?

ALK e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofets'e. Liphetoho tsa ALK li ka sitisa litsela tsa bohlokoa tsa biochemical, ho kenyelletsa le MAPK Signaling le Growth Factor Signaling, tse susumetsang nts'etsopele ea mofetše. Haeba phanele ea liphatsa tsa lefutso tsa hau e senola liphetoho ho ALK tse amanang le Central Nervous System, nahana ka ho kenyelletsa li-supplement tsa Ashitaba moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa hantle litsela tse kang MAPK Signaling, ho rua molemo ka ho fana ka tšehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa ALK le mathata a amanang le bophelo bo botle.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Ashitaba, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• cBioPortal bakeng sa Cancer Genomics
• Ts'ebetso e khahlanong le ho ruruha le anticholinesterase ea li-flavonoid tse tšeletseng tse arohaneng le mefuta ea Polygonum le Dorstenia.
• Kalafo ea mofets'e e theha sebopeho sa boikoetliso ba clonal hematopoiesis.
• Isobavachalcone e arohaneng le Psoralea corylifolia e thibela ho ata ha lisele le ho etsa hore apoptosis e be teng ka ho thibela tsela ea AKT / GSK-3β / β-catenin ka lisele tsa kankere ea colorectal.
• Isobavachalcone e na le litlamorao tsa anti-proliferative le pro-apoptotic liseleng tsa mofetše oa sebete sa motho ka ho lebisa tsela ea matšoao ea ERKs/RSK2.
• Ema ho thuto ea mofetše mohato oa Ib oa pan-phosphoinositide-3-kinase inhibitor buparlisib e nang le letrozole ho estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
• [Tlhaloso ea Cyclooxygenase-2 liseleng tsa mofetše oa esophageal le ho kenngoa ke mitomycin C].