Lijo tsa Polycythemia Vera!

Selelekela

Lijo tsa Polycythemia Vera li lokela ho etsoa ka bomong bakeng sa motho ka mong hape li tlameha ho ikamahanya le maemo ha kalafo ea mofetše kapa liphatsa tsa lefutso tsa hlahala li fetoha. Ho iketsetsa motho le ho ikamahanya le maemo ho tlameha ho nahanela metsoako eohle e sebetsang kapa li-bioactive tse fumanehang lijong tse fapaneng mabapi le baeloji ea mofetše, liphatsa tsa lefutso, kalafo, maemo a bophelo le likhetho tsa lijo. Kahoo le hoja phepo e nepahetseng e le e 'ngoe ea liqeto tsa bohlokoa haholo tseo mokuli oa mofetše le motho ea kotsing ea mofetše a lokelang ho li etsa - mokhoa oa ho khetha lijo tseo u ka li jang ha se mosebetsi o bonolo.

Polycythemia vera ke boloetse bo sa tloaelehang, bo sa foleng, ba lisele tsa mali, bo khetholloang e le myeloproliferative neoplasm kapa MPN. Polycythemia vera e bakoa ke tlhahiso e feteletseng ea lisele tse khubelu tsa mali (RBCs) mokong oa masapo, hammoho le tlhahiso e feteletseng ea lisele tse tšoeu tsa mali le liplatelete. E ama banna ba bangata hanyane ho feta basali mme e etsahala hangata ho batho ba fetang lilemo tse 60. Batho ba nang le polycythemia vera ba na le palo e phahameng ka ho sa tloaelehang ea li-RBC tse potolohang maling a bona, e leng se etsang hore mali a teteane le ho eketseha ka molumo (boemo bo bitsoang hyperviscosity). Mali a teteaneng a ka 'na a se ke a phalla ka har'a methapo e menyenyane ea mali (capillaries) hantle. Matšoao a mangata a ka hlaha ho batho ba nang le polycythemia vera ho kenyelletsa matšoao a sa tobang joalo ka hlooho e opang, mokhathala, bofokoli, ho tsekela, ho hlohlona ha letlalo; spleen e atolositsoeng (splenomegaly); mefuta e fapaneng ya mathata a mala; le kotsi e kholo ea ho thehoa ha lesela la mali, e leng se ka thibelang ho phalla ha mali lithong tsa bohlokoa. Ho feta 90% ea batho ba nang le polycythemia vera ba na le phetoho mofuteng oa JAK2. Kalafo ea polycythemia vera e reretsoe ho fokotsa maemo a lisele tse khubelu tsa mali le ho thibela mathata a ho thehoa ha lesela la mali (thrombosis). Mekhoa ea phekolo e kenyelletsa phlebotomy (ho ntša mali ka linako tse itseng) ho fokotsa molumo oa li-RBC tse potolohang e le hore mali a phalle hantle. Bakuli ba boetse ba phekoloa ka lithethefatsi tsa myelosuppressive tse kang hydroxyurea le busulfan, tse thibelang ho thehoa ha lisele tsa mali mokong oa masapo. Ho na le liphekolo tse ling tse kang aspirin ea tekanyo e tlase le sethethefatsi se sa tsoa amoheloa se lebisitsoeng ho enzyme ea JAK2 e fumanoang e sebetsa. Ho phaella moo, tlhokomelo e tšehetsang ka phepo e nepahetseng (lijo le li-supplement tsa tlhaho) tse nang le li-bioactives tsa tlhaho ho fetola litsela tse bakang lefu li ka thusa ho ntlafatsa bophelo bo botle ba mokuli.

Bakeng sa Polycythemia Vera na ho na le taba hore na motho o ja meroho, litholoana, linate, lipeo life?

Potso e atileng haholo ea phepo e botsoang ke bakuli ba mofets'e le batho ka bomong ba kotsing ea mofets'e ke - bakeng sa mofetše joalo ka Polycythemia Vera na ho na le taba hore na ke ja lijo life le tseo ke sa li jeng? Kapa haeba ke latela lijo tse thehiloeng limela na hoo ho lekane bakeng sa mofetše joalo ka Polycythemia Vera?

Ka mohlala, na ho na le taba hore Parsnip ea meroho e jeoa haholo ha e bapisoa le Common Beet? Na ho na le phapang e teng haeba tholoana ea Black Elderberry e ratoa ho feta Black Mulberry? Hape haeba khetho e tšoanang e etsoa bakeng sa linate/peo e kang Black Walnut holim'a Chestnut ea Europe le bakeng sa limela tse kang Alfalfa holim'a Yellow Wax Bean. 'Me haeba seo ke se jang se bohlokoa - joale motho o tseba joang lijo tse buelloang bakeng sa Polycythemia Vera 'me na ke karabo e tšoanang ho bohle ba nang le tlhahlobo e tšoanang kapa kotsi ea lefutso?

Ee! Lijo tseo u li jang li bohlokoa bakeng sa Polycythemia Vera!

Litlhahiso tsa lijo li ka 'na tsa se ke tsa tšoana ho bohle' me li ka fapana esita le bakeng sa tlhahlobo e tšoanang le kotsi ea lefutso.

Lijo tsohle (meroho, litholoana, linate, lipeo, li-pulses, oli joalo-joalo) le litlatsetso tsa phepo li entsoe ka metsoako e fetang e le 'ngoe e sebetsang ea molek'hule kapa bio-active ka tekanyo le bongata bo fapaneng. Sejo se seng le se seng se sebetsang se na le mokhoa o ikhethileng oa ts'ebetso - e ka bang ts'ebetso kapa ho thibela litsela tse fapaneng tsa biochemical. Lijo le li-supplement tse khothalletsoang habonolo ke tse sa bakeng keketseho ea limolek'hule tsa mofetše empa li li fokotsa. Ho seng joalo, lijo tseo ha lia lokela ho khothaletsoa. Lijo li na le metsoako e mengata e sebetsang - ka hona, ha u hlahloba lijo le li-supplement, u lokela ho nahana ka phello ea metsoako eohle e sebetsang ka bonngoe ho e-na le hore u nahane ka bonngoe.

Ka mohlala Black Elderberry e na le metsoako e sebetsang ea Formononetin, Phloretin, Apigenin, Quercetin, Stigmasterol. 'Me Black Mulberry e na le metsoako e sebetsang ea Formononetin, Phloretin, Apigenin, Quercetin, Stigmasterol le mohlomong tse ling.

Phoso e tloaelehileng e entsoeng ha ho etsoa qeto le ho khetha lijo tseo u ka li jang bakeng sa Polycythemia Vera - ke ho hlahloba feela metsoako e sebetsang e khethiloeng e fumanehang lijong le ho hlokomoloha tse ling kaofela. Hobane metsoako e fapaneng e sebetsang e fumanehang lijong e kanna ea ba le litlamorao tse fapaneng ho bakhanni ba mofetše - u ke ke ua khetha metsoako e sebetsang lijong le li-supplement bakeng sa ho etsa qeto ea phepo e nepahetseng bakeng sa Polycythemia Vera.

EE – LIKHETHO TSA LIJO LI BOHLOKOA BAKENG SA KANKERE. LIQETO TSA PHEPO LI TLAMEHA HO NAHANA KA LITABA TSOHLE TSA LIJO.

Tsebo e Hlokahalang Bakeng sa Phepo ea Boipheliso bakeng sa Polycythemia Vera?

Phepo ea motho ka mong bakeng sa mofetše joalo ka Polycythemia Vera e na le lijo tse khothaletsoang / li-supplement; lijo tse sa khothaletsoang tse nang le mohlala oa diresepe tse etelletsang pele tšebeliso ea lijo tse khothaletsoang. Mohlala oa phepo e nepahetseng o ka bonoa ho sena link tsa.

Ho etsa qeto ea hore na ke lijo life tse khothalelitsoeng kapa che ho rarahane haholo, ho hloka boiphihlelo ho Polycythemia Vera biology, mahlale a lijo, liphatsa tsa lefutso, biochemistry hammoho le kutloisiso e ntle ea hore na kalafo ea mofets'e e sebetsa joang le bofokoli bo amanang le bona boo kalafo e ka emisang ho sebetsa.

BONYENYANE BO TSEBO BOHLOKOA BAKENG SA PHEPO MOTHO BATHO BA KANKERE KE: BOLOJI YA KANKERE, SAENSE YA DIJO, DIPHEKO LA MOFEPO LE LIFUTSO.

Litšobotsi tsa mofets'e joalo ka Polycythemia Vera

Lik'hemik'hale tsohle tse kang Polycythemia Vera li ka khetholloa ka mokhoa o ikhethang oa litsela tsa lik'hemik'hale - mekhoa ea ho saena ea Polycythemia Vera. Litsela tsa biochemical tse kang RAS-RAF Signaling, Cytokine Signaling, JAK-STAT Signaling, Hematopoiesis ke karolo ea tlhaloso ea signature ea Polycythemia Vera. Liphatsa tsa lefutso tsa mofetše oa motho ka mong li ka fapana, ka hona, tekeno ea bona ea mofetše e ka ikhetha.

Liphekolo tse sebetsang hantle bakeng sa Polycythemia Vera li hloka ho ela hloko mekhoa ea lik'hemik'hale e amanang le eona bakeng sa mokuli e mong le e mong oa mofetše le motho ea kotsing ea lefutso. Ka hona liphekolo tse fapaneng tse nang le mekhoa e fapaneng ea liketso li sebetsa hantle ho bakuli ba fapaneng. Ka mokhoa o ts'oanang le ka mabaka a ts'oanang lijo le li-supplement li hloka ho etsoa ka bomong bakeng sa motho ka mong. Ka hona, lijo tse ling le li-supplement li khothaletsoa bakeng sa Polycythemia Vera ha u nka kalafo ea mofetše Ruxolitinib, 'me lijo tse ling le li-supplement ha li khothalletsoe.

Mehloli e kang cBioPortal 'me ba bang ba bangata ba fana ka lintlha tse sa tsejoeng tse tsoang litekong tsa bongaka bakeng sa matšoao ohle a mofetše. Lintlha tsena li na le lintlha tsa boithuto ba tleliniki joalo ka boholo ba sampole / palo ea bakuli, lihlopha tsa lilemo, bong, morabe, kalafo, sebaka sa tumor le liphetoho life kapa life tsa lefutso.

JAK2, TET2, DNMT3A, SH2B3 le ARID2 ke mefuta e kaholimo-limo e tlalehiloeng bakeng sa Polycythemia Vera. JAK2 e tlalehoa ho 76.5% ea bakuli ba baemeli ho pholletsa le liteko tsohle tsa bongaka. Mme TET2 e tlalehile ka 21.6%. Lintlha tse kopaneng tsa bakuli li akaretsa lilemo ho tloha ho. 0.0% ea lintlha tsa mokuli li khetholloa e le banna. Polycythemia Vera biology hammoho le liphatsa tsa lefutso tse tlalehiloeng hammoho li hlalosa palo ea batho ba emetseng mekhoa ea lik'hemik'hale ea mofetše. Haeba liphatsa tsa lefutso tsa mofetše kapa liphatsa tsa lefutso tse kenyang kotsi le tsona li tsejoa, seo se lokela ho sebelisoa hape bakeng sa ho ja lijo.

LIKHETHO TSA PHEPO LI LOKELA HO TŠOANA LE MOTHO E MONG LE E MONG LE SAENYO EA MOTHO EA KANKERE.

Lijo le Tlatsetso bakeng sa Polycythemia Vera

Bakeng sa Bakuli ba Kankere

Bakuli ba mofetše ba nakong ea kalafo kapa ba tlhokomelong ea pholiso ba lokela ho etsa liqeto mabapi le lijo le li-supplement - bakeng sa lik'hilojule tse hlokahalang tsa lijo, ho laola litla-morao life kapa life tsa kalafo le bakeng sa taolo e ntlafetseng ea mofetše. Lijo tsohle tse thehiloeng ho limela ha li lekane, 'me ho khetha le ho etelletsa pele lijo tse ikhethileng le tse etselitsoeng kalafo e tsoelang pele ea mofets'e ho bohlokoa ebile ho rarahane. Mehlala ke ena e fanang ka litataiso bakeng sa ho etsa liqeto tsa phepo e nepahetseng.

Khetha Meroho PARSNIP kapa COMMON BEET?

Meroho ea Parsnip e na le metsoako e mengata e sebetsang kapa bioactives tse kang Formononetin, Phloretin, Quercetin, Stigmasterol, Curcumin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang JAK-STAT Signaling, MAPK Signaling, Cytokine Signaling le MYC Signaling le tse ling. Parsnip e khothaletsoa bakeng sa Polycythemia Vera ha kalafo e tsoelang pele ea mofetše e le Ruxolitinib. Lebaka ke hobane Parsnip e fetola mekhoa ea biochemical eo ho tlalehiloeng ka mahlale ho hlokomelisa phello ea Ruxolitinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho e tloaelehileng ea Beet ke Formononetin, Phloretin, Apigenin, Stigmasterol, Curcumin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang DNA Repair le Oncogenic Cancer Epigenetics le tse ling. Common Beet ha e khothalletsoe bakeng sa Polycythemia Vera ha kalafo e tsoelang pele ea mofets'e e le Ruxolitinib hobane e fetola mekhoa ea biochemical e etsang hore kalafo ea mofets'e e se ke ea sebetsa kapa e se ke ea arabela.

PARSNIP EA MOROE E KHOTHATSOA HO FETISISA BEET E TLOAELEHANG BAKENG SA Polycythemia Vera LE PHEKO Ruxolitinib.

Khetha Litholoana BLACK MULBERRY kapa BLACK ELDERBERRY?

Fruit Black Mulberry e na le metsoako e mengata e sebetsang kapa bioactives tse kang Formononetin, Phloretin, Apigenin, Quercetin, Stigmasterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang JAK-STAT Signaling, Hypoxia, MAPK Signaling le MYC Signaling le tse ling. Black Mulberry e buelloa bakeng sa Polycythemia Vera ha kalafo ea mofetše e tsoelang pele e le Ruxolitinib. Sena ke hobane Black Mulberry e fetola mekhoa ea biochemical eo ho tlalehiloeng ka mahlale ho hlokomelisa phello ea Ruxolitinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana Black Elderberry ke Formononetin, Phloretin, Apigenin, Quercetin, Stigmasterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang DNA Repair le Oncogenic Cancer Epigenetics le tse ling. Black Elderberry ha e khothalletsoe bakeng sa Polycythemia Vera ha kalafo ea mofets'e e tsoelang pele e le Ruxolitinib hobane e fetola litsela tsa biochemical tse etsang hore kalafo ea mofets'e e se ke ea hlola e arabela kapa e se ke ea arabela.

LITHOLOANA TŠE TŠO E TŠOANELO E KHOTHATSOA HO FETISISA BLACK ELDERBERRY BAKENG SA Polycythemia Vera LE PHEKO Ruxolitinib.

Khetha Nut BLACK WALNUT kapa EUROPEAN CHESTNUT?

Black Walnut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Formononetin, Phloretin, Apigenin, Quercetin, Curcumin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka RAS-RAF Signaling, MAPK Signaling le MYC Signaling le tse ling. Black Walnut e buelloa bakeng sa Polycythemia Vera ha phekolo ea kankere e tsoelang pele e le Ruxolitinib. Lebaka ke hobane Walnut e Ntšo e fetola litsela tseo tsa biochemical tse tlalehiloeng ka mahlale ho hlokomelisa phello ea Ruxolitinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa Chestnut ea Europe ke Formononetin, Phloretin, Apigenin, Quercetin, Stigmasterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang DNA Repair le Oncogenic Cancer Epigenetics le tse ling. Chestnut ea Europe ha e khothalletsoe bakeng sa Polycythemia Vera ha kalafo ea mofetše e tsoelang pele e le Ruxolitinib hobane e fetola mekhoa ea biochemical e etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

BLACK WALNUT E KHOTHATSOE HO FETA CHESTNUT EA EUROPE BAKENG SA Polycythemia Vera LE PHEKO Ruxolitinib.

Bakeng sa Batho ba nang le Kotsi ea Liphatsa tsa Kankere

Potso e botsoang ke batho ba nang le kotsi ea lefutso ea Polycythemia Vera kapa nalane ea lelapa ke "Ke Lokela ho Ja Eng e Fapaneng le Pele?" le kamoo ba lokelang ho khetha lijo le li-supplement bakeng sa ho laola likotsi tsa lefu lena. Kaha bakeng sa kotsi ea mofets'e ha ho letho le ka etsoang mabapi le kalafo - liqeto tsa lijo le li-supplement li fetoha tsa bohlokoa 'me e le e' ngoe ea lintho tse fokolang haholo tse ka etsoang. Lijo tsohle tse thehiloeng ho limela ha li lekane 'me li ipapisitse le liphatsa tsa lefutso le mokhoa oa ho saena - khetho ea lijo le li-supplement li lokela ho etsoa ke motho ka mong.

Khetha meroho CAULIFLOWER kapa KOHLRABI?

Cauliflower ea meroho e na le metsoako e mengata e sebetsang kapa bioactives tse kang Curcumin, Formononetin, Bergapten, Isoliquiritigenin, Catechol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Chemokine Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling le MYC Signaling le tse ling. Cauliflower e kgothaletswa bakeng sa kotsi ya Polycythemia Vera ha kotsi e amanang le lefutso e le ARID2. Sena ke hobane Cauliflower e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho Kohlrabi ke Quercetin, Curcumin, Formononetin, Bergapten, Isoliquiritigenin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka PI3K-AKT-MTOR Signaling le Hematopoiesis le tse ling. Kohlrabi ha e khothalletsoe ha kotsi ea Polycythemia Vera e amahanngoa le kotsi ea lefutso e le ARID2 hobane e eketsa litsela tsa eona.

CAULIFLOWER EA MERO E KHOTHATSOENG HO FETISISA KOHLRABI BAKENG SA ARID2 Genese RISK EA KANKERE.

Khetha Fruit RED RASPBERRY kapa PUMMELO?

Litholoana tsa Raspberry tse khubelu li na le metsoako e mengata e sebetsang kapa bioactives tse kang Quercetin, Ellagic Acid, Curcumin, Formononetin, Bergapten. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang MYC Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling le Hematopoiesis le tse ling. Raspberry e khubelu e khothaletsoa kotsing ea Polycythemia Vera ha kotsi ea lefutso e amanang le ARID2. Sena ke hobane Red Raspberry e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona ba saena.

Tse ling tsa metsoako e sebetsang kapa bioactives ka litholoana Pummelo ke Quercetin, Curcumin, Apigenin, Formononetin, Bergapten. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka PI3K-AKT-MTOR Signaling le Hematopoiesis le tse ling. Pummelo ha e khothalletsoe ha kotsi ea Polycythemia Vera e amahanngoa le kotsi ea lefutso e le ARID2 hobane e eketsa litsela tsa eona.

RASPBERRY YA THOLOANA E KHIBIDU E KHOTHATSOA HO FETISISA PUMMELO BAKENG SA ARID2 genetic RISK OF CANCER.

Khetha Nut BUTTERNUT kapa CASH WUT?

Butternut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Curcumin, Myricetin, Apigenin, Formononetin, Bergapten. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang JAK-STAT Signaling, MYC Signaling, PI3K-AKT-MTOR Signaling le Hematopoiesis le tse ling. Butternut e khothaletsoa bakeng sa kotsi ea Polycythemia Vera ha kotsi ea lefutso e amanang le ARID2. Lebaka ke hobane Butternut e eketsa litsela tsa biochemical tse khahlano le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives ho Cashew Nut ke Quercetin, Curcumin, Myricetin, Formononetin, Bergapten. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics le MYC Signaling le tse ling. Cashew Nut ha e khothalletsoe ha kotsi ea Polycythemia Vera e amahanngoa le kotsi ea lefutso e le ARID2 hobane e eketsa litsela tsa eona.

BUTTERNUT E KHOTHATSOA HO HOLIMO HO FETISISA KOTSI EA K'HASHEW BAKENG SA ARID2 genetic RISK EA KANKERE.

Ha re phethela

Lijo le Lisebelisoa tse khethiloeng ke liqeto tsa bohlokoa bakeng sa mofetše joalo ka Polycythemia Vera. Bakuli ba Polycythemia Vera le batho ba nang le kotsi ea lefutso ba lula ba e-na le potso ena: "Ke lijo life le li-supplement tsa phepo tse khothalletsoang ho 'na le tse sa buelloang?" Ho na le tumelo e tloaelehileng eo e leng maikutlo a fosahetseng a hore lijo tsohle tse thehiloeng limela li ka ba molemo kapa che empa li ke ke tsa e-ba kotsi. Lijo tse ling le li-supplement li ka kena-kenana le phekolo ea mofetše kapa tsa khothalletsa bakhanni ba limolek'hule tsa mofetše.

Ho na le mefuta e fapaneng ea matšoao a mofets'e joalo ka Polycythemia Vera, e 'ngoe le e' ngoe e na le liphatsa tsa lefutso tse fapaneng tse nang le mefuta e fapaneng ea genomic ho motho ka mong. Ho feta moo kalafo e 'ngoe le e' ngoe ea mofetše le chemotherapy e na le mokhoa o ikhethileng oa ts'ebetso. Sejo se seng le se seng joalo ka Parsnip se na le li-bioactive tse fapaneng ka bongata bo fapaneng, tse nang le tšusumetso litseleng tse fapaneng le tse ikhethileng tsa lik'hemik'hale tsa biochemical. Tlhaloso ea phepo e nepahetseng ke likhothaletso tsa motho ka mong bakeng sa sesupo sa mofetše, kalafo, liphatsa tsa lefutso, mokhoa oa bophelo le lintlha tse ling. Liqeto tsa phepo e nepahetseng bakeng sa mofetše li hloka tsebo ea biology ea mofets'e, mahlale a lijo le kutloisiso ea liphekolo tse fapaneng tsa chemotherapy. Qetellong ha ho e-na le liphetoho tsa phekolo kapa li-genomics tse ncha li khetholloa - phepo e nepahetseng e hloka ho hlahlojoa bocha.

Tharollo ea motho ka mong ea phepo e nepahetseng ea addon e etsa hore ho etsa liqeto ho be bonolo 'me e tlose mehopolo eohle ho araba potso e reng, "Ke lijo life tseo ke lokelang ho li khetha kapa ho se khethe bakeng sa Polycythemia Vera?". Sehlopha sa li-addon tse nang le taeo e mengata se kenyelletsa lingaka tsa mofetše, bo-ramahlale ba bongaka, baenjiniere ba mananeo le bo-ramahlale ba data.

References

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• https://rarediseases.org/rare-diseases/polycythemia-vera