Nderipi gomarara raizobatsirikana nekubatanidza Shiitake Mushroom mukudya kwavo?

Muchidimbu

Shiitake Mushroom inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweShiitake Mushroom yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Shiitake Mushroom inogona kubatsira avo vane Primary Solitary Fibrous Tumor vari pasi peAvastin, asi zvingasava zvakanaka kune varwere vanowana Radiation yePrimary Urethral Squamous Cell Carcinoma. Uyezve, nepo Shiitake Mushroom inogona kubatsira vanhu vane genetic risk factor, inogona kunge isingafungidzirwe kune avo vane imwe genetic njodzi "ALK". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweShiitake Mushroom kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha zvakaita serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Shiitake Mushroom iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, kutarisa kune yakazara mhedzisiro yezvinhu zvese zvinoshanda muzvokudya/zvinowedzera zvakaita seShiitake Mushroom panzvimbo yekuongorora chimwe nechimwe chinoshandiswa chakasiyana kana kuregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Unofanira kubatanidza Shiitake Mushroom mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Shiitake Mushroom kana uine genetic predisposition kune cancer yakabatana nejini? Ko kana pachinzvimbo chako genetic ngozi ichibva kune ALK gene? Zvinobatsira here kuisa Shiitake Mushroom mukudya kwako kana ukawanikwa uine Primary Urethral Squamous Cell Carcinoma, kana kuti chirwere chako chiri Primary Solitary Fibrous Tumor? Uyezve, manwiro ako eShiitake Mushroom anofanira kugadziriswa sei kana uri kurapwa neAvastin kana kana chirongwa chako chekurapa chichibva kuAvastin kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Shiitake Mushroom ndezvakasikwa, saka zvinogara zvichibatsira' kana kuti 'Shiitake Mushroom inowedzera kusadzivirirwa' hazvina kukwana pasarudzo dzechikafu/ dzekuwedzera.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekusanganisira Shiitake Mushroom mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo dzekubatanidza chikafu kana ma supplements seShiitake Mushroom mukudya kwako nekuda kwemabhenefiti ayo, unofanirwa kufunga nezvese mhedzisiro yebiochemical yezvese zvinongedzo, uchifunga nezvemhando dzakadai serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic. predispositions, uye mararamiro esarudzo.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, sePrimary Solitary Fibrous Tumor kana Primary Urethral Squamous Cell Carcinoma, nzira dzekurapa dzinoda kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume. ”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, seShiitake Mushroom. Ko genetic njodzi yegomarara kubva mukuchinjika mune imwe gene ine zvakafanana biochemical nzira nzira sekuchinja muALK? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Solitary Fibrous Tumor inofanana nePrimary Urethral Squamous Cell Carcinoma? Uyezve, kutariswa kwekudya kunoramba kwakafanana here kune avo vari kuita Radiation sekune avo vanogamuchira Avastin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Shiitake Mushroom – A Nutritional Supplement

Iyo yekuwedzera Shiitake Mushroom inosanganisa huwandu hwezvinhu zvinoshanda, zvinosanganisira Linoleic Acid, Palmitic Acid, Glycine, L-phenylalanine uye L-leucine, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling, RAS-RAF Signaling, NFKB Signaling uye Nucleotide metabolism, iyo inoronga zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera seShiitake Mushroom, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Shiitake Mushroom kwegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapwa kwegomarara, kushandiswa kweShiitake Mushroom haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Shiitake Mushroom Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivisa Shiitake Mushroom mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eShiitake Mushroom anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo aripo, zvimwe zvekuwedzera zviri kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Shiitake Mushroom yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga nezvemunhu. muzvisarudzo zvakadaro.

1. Ko Shiitake Mushroom Supplements ichabatsira Varwere vePrayimari yeUrethral Squamous Cell Carcinoma vari kurapwa neRadiation?

Yekutanga Urethral Squamous Cell Carcinoma inoratidzwa nekumwe kuchinjika kwemajini, anoti BLM, BRCA1 uye CTCF, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya RAS-RAF Signaling, Androgen Signaling uye DNA Kugadzirisa. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Shiitake Mushroom yekuwedzera, iyo inobata iyo RAS-RAF Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Urethral Squamous Cell Carcinoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Shiitake Mushroom Supplements ichabatsira Varwere Vekutanga Vega Fibrous Tumor Varwere vari kurapwa neAvastin?

Primary Solitary Fibrous Tumor inotaridzwa neiyo chaiyo genetic mutations, senge BRD4, FLI1 uye KMT2C, izvo zvinoguma nekuchinja mune biochemical nzira, kunyanya MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation uye Amino Acid Metabolism. Kubudirira kwekurapwa kwegomarara, senge Avastin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Shiitake Mushroom yekuwedzera isarudzo ine musoro kune avo vane Primary Solitary Fibrous Tumor iri kuita Avastin. Izvi zvinodaro nekuti Shiitake Mushroom inopesvedzera nzira dzakadai seMYC Signaling, iyo inogona kuvharisa zvinhu zvinotyaira Primary Solitary Fibrous Tumor kana kubatsira kushanda kweAvastin.

3. Ko Shiitake Mushroom Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ALK gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yekenza.

Kuchinja kweiyo ALK gene kunokanganisa nzira dzebiochemical kana maitiro, akadai seNFKB Signaling uye Growth Factor Signaling, ayo anobatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muALK ine chekuita nenjodzi yakawedzera yeCentral Nervous System, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Shiitake Mushroom. Izvi zvinodaro nekuti kuwedzera Shiitake Mushroom kunokanganisa nzira dzakaita seNFKB Chiratidzo, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ALK mutation uye ane hukama nekenza mamiriro.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seShiitake Mushroom, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Kuita kwePPAR gamma uye delta ne conjugated linoleic acid inopindirana kudzivirira kubva mukuedza kwechirwere chechirwere chechirwere.
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• cBioPortal yeCancer Genomics
• cBioPortal yeCancer Genomics
• Basa re tumor microenvironment mukupikisa anti-angiogenic therapy.