Nderipi gomarara raizobatsirwa nekubatanidza Horse Chestnut mukudya kwavo?

Muchidimbu

Horse Chestnut inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweBhiza Chestnut kune varwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, mamwe marapirwo, uye bundu genetics. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Horse Chestnut inogona kubatsira avo vane Primary Mucosal Melanoma yeUrethra iri pasi peDoxorubicin, asi zvingasava zvakanaka kune varwere vanowana Radiation yePrimary Sclerosing Epithelioid Fibrosarcoma. Uyezve, nepo Horse Chestnut inogona kubatsira vanhu vane genetic risk factor "CDH1", inogona kunge isingafungidzirwe kune avo vane imwe genetic njodzi "ASXL1". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pamusoro pekukodzera kweBhiza Chestnut kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Horse Chestnut iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, kutarisa kune yakazara mhedzisiro yezvinhu zvese zvinoshanda mukudya / zvinowedzera seBhiza Chestnut pachinzvimbo chekuongorora chimwe nechimwe chinoshanda chega kana kuchiregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kuisa Horse Chestnut mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinogoneka here kushandisa Horse Chestnut kana uine genetic predisposition kune cancer yakabatana neCDH1 gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuASXL1 gene? Zvinobatsira here kuisa Horse Chestnut mukudya kwako kana ukaonekwa uine Primary Sclerosing Epithelioid Fibrosarcoma, kana kuti chirwere chako chiri Primary Mucosal Melanoma yeUrethra? Uyezve, manwiro ako eBhiza Chestnut anofanira kugadziriswa sei kana uri kurapwa neDoxorubicin kana chirongwa chako chekurapa chichibva kuDoxorubicin kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Bhiza Chestnut ndezvakasikwa, saka zvinogara zvichibatsira' kana kuti 'Bhiza Chestnut rinowedzera kusadzivirirwa' harina kukwana kune ruzivo rwekudya / yekuwedzera sarudzo.

Uyezve, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Horse Chestnut mukudya kwako kana pane shanduko mukurapa kwako. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seBhiza Chestnut mukudya kwako nekuda kwemabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga nezvemhando serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic. predispositions, uye mararamiro esarudzo.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, sePrimary Mucosal Melanoma yeUrethra kana Primary Sclerosing Epithelioid Fibrosarcoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume kana mukadzi. .”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, seBhiza Chestnut. Ko genetic njodzi yegomarara kubva mukuchinjika muCDH1 ine zvakafanana biochemical nzira nzira sekuchinja muASXL1? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Mucosal Melanoma yeUrethra inoenzana nePrimary Sclerosing Epithelioid Fibrosarcoma? Uyezve, kutariswa kwechikafu kunoramba kwakafanana here kune avo vari kuita Radiation sevaya vanogamuchira Doxorubicin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Horse Chestnut – A Nutritional Supplement

Iyo yekuwedzera Horse Chestnut inotenderedza huwandu hwezvinhu zvinoshanda, zvinosanganisira Esculin neAescin, yega yega iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya Cell Cycle Checkpoints, TGFB Signaling uye Inflammation, iyo inoronga zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza iwo akakodzera ekuwedzera seBhiza Chestnut, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Horse Chestnut yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweBhiza Chestnut haisi sarudzo yepasirese inokodzera vese cancer asi inoda kuve munhu.

Kusarudza Horse Chestnut Supplements

Kutarisana nemubvunzo 'Ndirini pandinofanira kudzivirira Horse Chestnut mumamiriro eCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu mumwe chete - inongo 'Inoenderana!'. Zvakafanana nemabatiro api neapi ekurapa cancer anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eHorse Chestnut anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo aripo, zvimwe zvekuwedzera zviri kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Horse Chestnut yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. muzvisarudzo zvakadaro.

1. Ko Horse Chestnut Supplements ichabatsira here Primary Sclerosing Epithelioid Fibrosarcoma Varwere vari kurapwa neRadiation?

Primary Sclerosing Epithelioid Fibrosarcoma inoratidzwa neakanyanya genetic mutations, anoti PBRM1, ATRX uye PIK3C2G, izvo zvinotungamira kune shanduko munzira dzebiochemical nzira, kunyanya TGFB Signaling uye Inositol Phosphate Signaling. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Horse Chestnut yekuwedzera, iyo inobata iyo TGFB Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Sclerosing Epithelioid Fibrosarcoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Horse Chestnut Supplements ichabatsira Primary Mucosal Melanoma yeUrethra Varwere vari kurapwa neDoxorubicin?

Primary Mucosal Melanoma yeUrethra inotaridzwa neakananga genetic mutations, seTP53, SMARCA4 uye FAT1, izvo zvinoguma nekuchinja kwebiochemical pathways, kunyanya Cell Cycle Checkpoints, Apoptosis, Androgen Signaling uye Chromatin Remodeling. Kushanda kwekurapa cancer, senge Doxorubicin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Horse Chestnut yekuwedzera isarudzo ine musoro kune avo vane Primary Mucosal Melanoma yeUrethra iri pasi peDoxorubicin. Izvi zvinodaro nekuti Bhiza Chestnut rinopesvedzera nzira dzakadai seSero Cycle Checkpoints, iyo inogona kuvharisa zvinhu zvinotyaira Primary Mucosal Melanoma yeUrethra kana kubatsira kushanda kweDoxorubicin.

3. Ko Horse Chestnut Supplements Yakachengeteka Kune Vane Utano Vanhu Vane ASXL1 Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ASXL1 gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muASXL1 gene inokanganisa nzira dzebiochemical kana maitirwo, akadai seInflammation, Oncogenic Cancer Epigenetics uye Suppressive Histone Methylation, ayo akabatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muASXL1 yakabatana nenjodzi yakawedzera yeChronic Myelomonocytic Leukemia, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Horse Chestnut. Izvi zvinodaro nekuti kuwedzera Horse Chestnut kunokanganisa nzira senge Inflammation, iyo inogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ASXL1 mutation uye ane hukama nekenza mamiriro.

4. Ko Horse Chestnut Supplements Yakachengeteka Kune Vanhu Vane Utano Vane CDH1 Mutation Associated Genetic Risk?

CDH1 inobata basa rakakosha mukuongorora njodzi yegomarara. Shanduko muCDH1 inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Cell Cycle Checkpoints, Adherens junction uye Epithelial kuenda kuMesenchymal Transition, iyo inokanganisa kukura kwegomarara. Kana genetic panel yako ichiratidza shanduko muCDH1 yakabatana neGastric Cancer, funga kuisa Horse Chestnut supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kukanganisa nzira dzakaita seCell Cycle Checkpoints, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane CDH1 shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seBhiza Chestnut, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Kupokana kwep53 knockout maseru kune doxorubicin kune hukama nekudzikiswa kuumbwa kweDNA strand breaks pane kukanganisa apoptotic kusaina.
• cBioPortal yeCancer Genomics
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Radio kuramba mumasero egomarara rezamu inoyananiswa kuburikidza neTGF-β kusaina, hybrid epithelial-mesenchymal phenotype uye cancer stem masero.