Nderipi gomarara raizobatsirikana nekubatanidza Hops mukudya kwavo?

Muchidimbu

Hops inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweHops kwevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe marapirwo, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Hops inogona kubatsira avo vane Primary Basal Cell Carcinoma vari pasi peVismodegib, asi zvinogona kunge zvisina kunaka kune varwere vanogamuchira Radiation yePrimary Adamantinoma. Uyezve, nepo maHops achigona kubatsira vanhu vane genetic risk factor "ALK", inogona kusapihwa kune avo vane imwe genetic njodzi "CDKN2A". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pamusoro pekukodzera kweHops kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Hops iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzechikafu akakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera seHops pachinzvimbo chekuongorora chimwe nechimwe chinoshanda chinoshandiswa zvakasiyana kana kusachifuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kubatanidza Hops mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Hops kana uine genetic predisposition kune cancer yakabatana neiyo ALK gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuCDKN2A gene? Zvinobatsira here kubatanidza Hops mukudya kwako kana ukabatwa nePrimary Adamantinoma, kana kuti chirwere chako chiri Primary Basal Cell Carcinoma? Uyezve, mashandisiro ako eHops anofanira kugadziriswa sei kana uri kurapwa neVismodegib kana chirongwa chako chekurapa chichibva kuVismodegib kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Hops ndezvakasikwa, saka zvinogara zvichibatsira' kana 'Hops inosimudzira kusadzivirirwa' hazvina kukwana kune ruzivo rwechikafu / chekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Hops mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seHops mukudya kwako kune mabhenefiti ayo, unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, yakadai sePrimary Basal Cell Carcinoma kana Primary Adamantinoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume.

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, senge Hops. Ko genetic njodzi yegomarara kubva mukushanduka muALK ine zvakafanana biochemical nzira nzira sekuchinja muCDKN2A? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Basal Cell Carcinoma inofanana nePrimary Adamantinoma? Uyezve, kutariswa kwechikafu kunoramba kwakafanana here kune avo vari kuenda kuRadiation sekune avo vanogamuchira Vismodegib? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Hops – A Nutritional Supplement

Iyo yekuwedzera Hops inotenderedza huwandu hwezvinhu zvinoshanda, zvinosanganisira Isoxanthohumol uye Humulone, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya RAS-RAF Signaling, Oxidative Stress uye Interferon Signaling, iyo inoronga zvakakosha zvegomarara padanho remaserura, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera ekuwedzera seHops, ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezvekushandisa Hops yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa gomarara, kushandiswa kweHops haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Hops Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivirira Hops mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eHops anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, zvimwe zvekuwedzera zviri kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Hops yakakodzera here kana kuti inofanirwa kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Hops Supplements ichabatsira Varwere veParamende Adamantinoma vari kurapwa neRadiation?

Primary Adamantinoma inoratidzwa neakanyanya genetic mutations, anoti ARHGAP45, PI4KB uye SDSL, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Oxidative Stress uye Inositol Phosphate Signaling. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Hops yekuwedzera, iyo inobata iyo Oxidative Stress, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Adamantinoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Hops Supplements ichabatsira here Varwere veBasal Cell Carcinoma vari kurapwa neVismodegib?

Primary Basal Cell Carcinoma inotaridzwa neiyo genetic mutations, yakadai sePTCH1, CSMD3 uye CSMD1, izvo zvinoguma nekuchinja mune biochemical pathways, kunyanya RAS-RAF Signaling. Kushanda kwekurapa cancer, seVismodegib, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Hops yekuwedzera isarudzo ine musoro kune avo vane Primary Basal Cell Carcinoma iri pasi peVismodegib. Izvi zvinodaro nekuti Hops inopesvedzera nzira dzakaita seRAS-RAF Signaling, iyo inogona kuvharisa zvinhu zvinotyaira Primary Basal Cell Carcinoma kana kubatsira kushanda kweVismodegib.

3. Ko Hops Supplements Yakachengeteka Kune Vane Hutano Vanhu Vane CDKN2A Mutation Yakabatana Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo CDKN2A gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muCDKN2A gene inokanganisa nzira dzebiochemical kana maitirwo, akadai seInterferon Signaling, Cell Cycle Checkpoints uye Cell Cycle, ayo anobatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yaratidza shanduko muCDKN2A ine chekuita nenjodzi yakawedzera yeGanda reGanda, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Hops. Izvi zvinodaro nekuti yekuwedzera Hops inopesvedzera nzira dzakaita seInterferon Signaling, iyo inogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo CDKN2A mutation uye ane hukama nekenza mamiriro.

4. Ko Hops Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

ALK inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muALK inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira RAS-RAF Kuratidzira uye Kukura Kwekuita Chiratidzo, izvo zvinokanganisa kukura kwegomarara. Kana genetic panel yako ichiratidza shanduko muALK yakabatana neCentral Nervous System, funga kuisa Hops supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kukanganisa nzira dzakaita seRAS-RAF Signaling, kubatsirwa nekupa rubatsiro rwakakodzera kune vanhu vane ALK mutations uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seHops, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Basa re KEAP1/NRF2 uye TP53 Mutations muLung Squamous Cell Carcinoma Development uye Radiation Resistance.
• Iyo Molecular Landscape yeRecurrent uye Metastatic Head uye Neck Cancers: Insights Kubva kune Precision Oncology Sequencing Platform.
• cBioPortal yeCancer Genomics
• Humulone inhibits phorbol ester-induced COX-2 kutaura muganda regonzo nekuvhara activation yeNF-kappaB uye AP-1: IkappaB kinase uye c-Jun-N-terminal kinase sezvingangoita zvinotarisirwa kumusoro kwepamusoro.
• cBioPortal yeCancer Genomics
• Kudzivirirwa kweangiogenesis ne humulone, acid inovava kubva kudoro hop.
• Pan-cancer kuongororwa kweiyo genomes yakazara.
• Electrochemical versus spectrophotometric assessment ye antioxidant basa rehop (Humulus lupulus L.) zvigadzirwa uye makemikari ega ega.
• Melanomas inoda HEDGEHOG-GLI kusaina kunodzorwa nekudyidzana pakati peGLI1 neRAS-MEK/AKT nzira.