Nderipi gomarara raizobatsirwa nekubatanidza Andrographis mukudya kwavo?

Muchidimbu

Andrographis inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweAndrographis yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe marapirwo, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Andrographis inogona kubatsira avo vane Primary Glioblastoma vari pasi peTemozolomide, asi zvingasava zvakanaka kune varwere vanogamuchira Carmustine yePrimary Pineoblastoma. Uyezve, nepo Andrographis ichigona kubatsira vanhu vane genetic risk factor "CDKN2A", inogona kusapihwa kune avo vane imwe genetic njodzi. Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweAndrographis kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, njodzi dzemajini, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Andrographis iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kugara uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzekudya akakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera seAndrographis pachinzvimbo chekuongorora chimwe nechimwe chinoshanda chekudya chakasiyana kana kuregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Unofanira kubatanidza Andrographis mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Andrographis kana uine genetic predisposition kune cancer yakabatana neCDKN2A gene? Ko kana pachinzvimbo njodzi yako yemajini ichibva kune imwe gene? Zvinobatsira here kuisa Andrographis mukudya kwako kana ukabatwa nePrimary Pineoblastoma, kana kuti chirwere chako chiri Primary Glioblastoma? Uyezve, kushandisa kwako kweAndrographis kunofanira kugadziriswa sei kana uri kurapwa neTemozolomide kana kana chirongwa chako chekurapa chichichinja kubva kuTemozolomide kuenda kuCarmustine? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Andrographis ndeyechisikigo, saka zvinogara zvichibatsira' kana 'Andrographis inowedzera kusadzivirirwa' hazvina kukwana kune ruzivo nezvekudya / yekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Andrographis mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seAndrographis mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, yakadai sePrimary Glioblastoma kana Primary Pineoblastoma, nzira dzekurapa dzinofanirwa kugadzirwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume.

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, seAndrographis. Ko genetic njodzi yegomarara kubva mukuchinjika muCDKN2A ine zvakafanana biochemical nzira nzira sekuchinja mujini? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Glioblastoma inoenzana nePrimary Pineoblastoma? Uyezve, kudya kwekudya kunoramba kwakafanana kune avo vari pasi peCarmustine kune avo vanogamuchira Temozolomide? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Andrographis - A Nutritional Supplement

Iyo yekuwedzera Andrographis inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Andrographolide, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya Cell Cycle uye Oncogenic Cancer Epigenetics, iyo inodzora zvinhu zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera ekuwedzera seAndrographis, ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Andrographis yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweAndrographis haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Andrographis Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivirira Andrographis mumamiriro eCancer' zvinonetsa nekuti mhinduro yacho yakasarudzika - inongodaro 'Inoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eAndrographis anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Andrographis yakakodzera here kana kuti inofanirwa kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Andrographis Supplements ichabatsira Varwere vePrimary Pineoblastoma vari kurapwa Carmustine?

Primary Pineoblastoma inoratidzwa neakanyanya genetic mutations, anoti ATR, ATM uye CREBBP, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Oncogenic Cancer Epigenetics, DNA Repair, Cell Cycle Checkpoints, G-protein-akabatana Receptor Signaling uye Immune Evasion Signaling. Kubudirira kwekurapwa kwegomarara, senge Carmustine, zvinoenderana nemaitiro ayo ekuita pane idzi nzira. Iyo yakanakira zano inosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye anoshanda nzira. Mumamiriro ezvinhu akadaro, kudzivirira kudya kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuenzaniso, iyo Andrographis yekuwedzera, iyo inobata iyo Oncogenic Cancer Epigenetics, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Pineoblastoma paunenge uchienda kuCarmustine. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Andrographis Supplements ichabatsira Varwere vePrimary Glioblastoma vari kurapwa neTemozolomide?

Primary Glioblastoma inocherechedzwa nechaiyo genetic mutations, seTRBV7-7, TAS2R46 uye TP53, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya Cell Cycle, Cell Cycle Checkpoints uye Apoptosis. Kubudirira kwekurapa kenza, seTemozolomide, inotarwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Andrographis yekuwedzera isarudzo ine musoro kune avo vane Primary Glioblastoma vari pasi peTemozolomide. Izvi zvinodaro nekuti Andrographis inokanganisa nzira dzakadai seSero Cycle, iyo inogona kuvharisa zvinhu zvinotyaira Primary Glioblastoma kana kubatsira kushanda kweTemozolomide.

3. Ko Andrographis Supplements Yakachengeteka Kune Vane Utano Vanhu Vane CDKN2A Mutation Associated Genetic Risk?

CDKN2A inoita basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muCDKN2A kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Cell Cycle Checkpoints uye Cell Cycle, izvo zvinokanganisa kukura kwegomarara. Kana genetic panel yako ikaratidza shanduko muCDKN2A yakabatana neGanda Reganda, funga kuisa Andrographis supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seSero Cycle, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane CDKN2A shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seAndrographis, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Kudhindisa zvigunwe kwemarudzi akasiyana-siyana ane DNA probes anogadzirwa kubva kune isina kufambiswa imwe-stranded DNA templates.
• cBioPortal yeCancer Genomics
• Andrographolide inopikisa utsi hwefodya-induced epithelial-mesenchymal transition uye pulmonary dysfunction kuburikidza ne-anti-inflammatory inhibiting HOTAIR.
• IDH1/2 mutation chiratidzo chekupona uye inofanotaura mhinduro kune chemotherapy yegiredhi II gliomas inorapwa pamwe chete neradiation therapy.
• cBioPortal yeCancer Genomics
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• MGMT-inhibitor pamwe chete neTGF-βRI inhibitor kana CDK 4/6 inhibitor inowedzera temozolomide kunzwa mutemozolomide-resistant glioblastoma masero.
• Iyo somatic genomic landscape ye glioblastoma.