Nderipi gomarara raizobatsirwa nekubatanidza Allspice mukudya kwavo?

Muchidimbu

Allspice inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevanorwara negomarara uye avo vari panjodzi yemagene. Asi, kuchengetedzeka uye kushanda kweAllspice yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Allspice inogona kubatsira avo vane Primary Solitary Fibrous Tumor vari pasi peAvastin, asi zvingasava zvakanaka kune varwere vanowana Gemcitabine yePrimary Sarcomaid Carcinoma yeUrinary Bladder. Uyezve, nepo Allspice inogona kubatsira vanhu vane genetic risk factor "CDH1", inogona kunge isingakurudzirwe kune avo vane imwe genetic njodzi "ALK". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweAllspice yemurwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Allspice iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu/zvinowedzera zvakaita seAllspice pachinzvimbo chekuongorora chega chega chega chega chega kana kufuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Unofanira kubatanidza Allspice mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Allspice kana uine genetic predisposition kune cancer yakabatana neCDH1 gene? Ko kana pachinzvimbo chako genetic ngozi ichibva kune ALK gene? Zvinobatsira here kuisa Allspice mukudya kwako kana uchinge wabatwa nePrimary Sarcomatoid Carcinoma yeUrinary Bladder, kana kuti chirwere chako chiri Primary Solitary Fibrous Tumor? Uyezve, manwiro ako eAllspice anofanira kugadziriswa sei kana uri kurapwa neAvastin kana chirongwa chako chekurapa chichibva kuAvastin kuenda kuGemcitabine? Izvo zvakakosha kuti uzive kuti zvirevo zvakareruka senge 'Allspice ndezvakasikwa, saka zvinogara zvichibatsira' kana 'Allspice inosimudzira kusadzivirirwa' hazvina kukwana kune ruzivo rwechikafu / chekuwedzera sarudzo.

Uyezve, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Allspice mukudya kwako kana pane shanduko mukurapa kwako. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seAllspice mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga nezvemhando serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, yakadai sePrimary Solitary Fibrous Tumor kana Primary Sarcomatoid Carcinoma yeUrinary Bladder, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye. murume kana mukadzi.”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, senge Allspice. Ko genetic njodzi yegomarara kubva mukuchinjika muCDH1 ine zvakafanana biochemical nzira nzira sekuchinja muALK? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Solitary Fibrous Tumor inofanana nePrimary Sarcomoid Carcinoma yeUrinary Bladder? Uyezve, kutariswa kwekudya kunoramba kwakafanana kune avo vari kuenda kuGemcitabine kune avo vanogamuchira Avastin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Allspice – A Nutritional Supplement

Kuwedzera kweAllspice kunosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Vitamin C, Folic Acid, Tetradecanoic Acid, 1,8-cineole uye Beta-caryophyllene, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling, PI3K-AKT-MTOR Signaling, Angiogenesis uye Chromatin Remodeling, iyo inodzora zvinhu zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza iwo akakodzera ekuwedzera seAllspice, ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezve kushandisa Allspice yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweAllspice haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Allspice Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivirira Allspice muchirevo chechinyorwa cheCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eAllspice anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti allspice yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Allspice Supplements ichabatsira here Primary Sarcomatoid Carcinoma yeUrinary Bladder Patients vari kurapwa neGemcitabine?

Primary Sarcomoid Carcinoma yeUrinary Bladder inoratidzwa neakanyanya genetic mutations, anoti ERCC2, KRAS uye LATS2, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya PI3K-AKT-MTOR Kuratidzira, DNA Kugadzirisa, Chromatin Remodeling, G-protein-yakabatana Receptor Signaling. , Chiratidzo cheKukura Chiratidzo uye Chiratidzo cheHippo. Kubudirira kwekurapwa kwegomarara, senge Gemcitabine, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuenzaniso, iyo Allspice yekuwedzera, iyo inobata iyo PI3K-AKT-MTOR Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Sarcomoid Carcinoma yeUrinary Bladder kana ichiitwa Gemcitabine. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Allspice Supplements ichabatsira here Primary Solitary Fibrous Tumor Varwere vari kurapwa neAvastin?

Primary Solitary Fibrous Tumor inotaridzwa neiyo chaiyo genetic mutations, senge BRD4, FLI1 uye KMT2C, izvo zvinoguma nekuchinja mune biochemical nzira, kunyanya MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation uye Amino Acid Metabolism. Kubudirira kwekurapwa kwegomarara, senge Avastin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Allspice yekuwedzera isarudzo ine musoro kune avo vane Primary Solitary Fibrous Tumor iri pasi peAvastin. Izvi zvinodaro nekuti Allspice inopesvedzera nzira dzakadai seMYC Signaling, iyo inogona kuvharisa zvinhu zvinotyaira Primary Solitary Fibrous Tumor kana kubatsira kushanda kweAvastin.

3. Ko Allspice Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ALK gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yekenza.

Kuchinja kweiyo ALK gene kunokanganisa nzira dzebiochemical kana maitiro, akadai seAngiogenesis uye Growth Factor Signaling, ayo akabatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel ikaratidza shanduko muALK yakabatana nenjodzi yakawedzera yeCentral Nervous System, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Allspice. Izvi zvinodaro nekuti yekuwedzera Allspice inopesvedzera nzira dzakaita seAngiogenesis, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ALK mutation uye ane hukama nekenza mamiriro.

4. Ko Allspice Supplements Yakachengeteka Kune Vanhu Vane Utano Vane CDH1 Mutation Associated Genetic Risk?

CDH1 inobata basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muCDH1 kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Chromatin Remodeling, Adherens junction uye Epithelial kuMesenchymal Transition, iyo inokonzera kukura kwekenza. Kana genetic panel yako ikaratidza shanduko muCDH1 yakabatana neGastric Cancer, funga kuisa Allspice supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seChromatin Remodeling, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane CDH1 mutations uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seAllspice, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• β-Caryophyllene zvine simba inhibits yakasimba bundu kukura uye lymph node metastasis yeB16F10 melanoma masero mumafuta ane mafuta akawanda-induced obese C57BL/6N mice.
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• cBioPortal yeCancer Genomics
• cBioPortal yeCancer Genomics
• JAK1/STAT3 regulatory effect ye β-caryophyllene paMG-63 osteosarcoma masero kuburikidza neROS-induced apoptotic mitochondrial nzira neDNA fragmentation.
• Sequential protooncogene kutaura mukuvandudza itsvo zvichitevera kukuvara kwerenal kwakanyanya.
• Basa reNF-kappaB uye Akt/PI3K mukupokana kwepancreatic carcinoma cell lines kurwisa gemcitabine-induced cell death.
• Basa re tumor microenvironment mukupikisa anti-angiogenic therapy.