Zvokudya zveGliosarcoma!

ziviso

Zvikafu zveGliosarcoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Gliosarcoma, bundu rehuropi risingawanzo uye rine hutsinye rinowanzoonekwa seyakasiyana yeglioblastoma, ine akasiyana pathological uye kiriniki maitiro. Pathology rondedzero yegliosarcoma inoratidza musanganiswa weglial uye sarcomatous zvinhu, zvichiisiyanisa kubva kune glioblastoma. Radiology, kunyanya MRI, inoita basa rakakosha mukuongororwa, kuratidza akasiyana ekufungidzira maitiro. Zviratidzo zvegliosarcoma zvakafanana nemamwe mapundu ehuropi, anosanganisira misoro, pfari, uye kushomeka kwetsinga. Hupenyu hwekutarisira uye kufungidzira kwevarwere vegliosarcoma kazhinji hurombo, nehuwandu hwekurarama zvinoenderana nezvinhu zvakasiyana senge nzvimbo yebundu uye hutano hwemurwere hwese. Iyo ICD-10 kodhi yegliosarcoma inomisa kupatsanurwa kwayo mumarekodhi ekurapa. Kunzwisisa zvinokonzeresa gliosarcoma inoramba iri nyaya yekuenderera mberi nekutsvaga. Kurapa kunowanzobatanidza kuvhiyiwa, chemotherapy, uye radiotherapy, asi kushanda kunogona kusiyana. Zvakaitika zvevakapona gliosarcoma zvinopa ruzivo rwakakosha mukurarama nechirwere ichi. Kuiswa kwegliosarcoma, kwakakosha pakuronga kurapwa, kunotevera nhungamiro yeWHO 2021, nenyaya zhinji dzichinzi IDH-wildtype WHO giredhi 4, zvichiratidza hukasha hwavo hwakanyanya. Kupera-kwe-hupenyu kuchengetedza chinhu chakakosha kutariswa mumatanho epamusoro, tichitarisa pakugadzirisa zviratidzo uye hupenyu hwehupenyu. Iyo yese manejimendi yegliosarcoma inoda nzira yemhando dzakasiyana siyana, ichibatanidza ichangoburwa yekutsvagisa uye nzira dzekurapa dzekuvandudza mhedzisiro kune avo vakabatwa neiri dambudziko reuropi bundu.

Kune Gliosarcoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kugomarara seGliosarcoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seGliosarcoma?

Semuenzaniso zvine basa here kana muriwo weCauliflower uchidyiwa zvakanyanya zvichienzaniswa neWelsh Onion? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Grapefruit/pummelo Hybrid? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro pePili Nut uye zvemapulses seAdzuki Bean pamusoro peCatjang Pea. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei chikafu chinokurudzirwa kuGliosarcoma uye ndiyo mhinduro imwechete kune wese munhu ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neGliosarcoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Curcumin, Apigenin, Caffeine, Lupeol. Uye Grapefruit/pummelo Hybrid ine zvinoshanda zvinosanganisa Curcumin, Apigenin, Caffeine, Lupeol, Lycopene uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheGliosarcoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri muchikafu zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yekudya kune Gliosarcoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Gliosarcoma?

Kudya kwakasarudzika kwegomarara senge Gliosarcoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muGliosarcoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seGliosarcoma

Magomarara ese akaita seGliosarcoma anogona kuratidzwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeGliosarcoma. Nzira dzeBiochemical seTWEAK Signaling, Growth Factor Signaling, PI3K-AKT-MTOR Signaling, Apoptosis chikamu chetsanangudzo ye siginecha yeGliosarcoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweGliosarcoma kunoda kuziva nzira dzakasaina dzebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemagene. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuGliosarcoma kana uchitora kurapwa kenza Temozolomide, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

TP53, TERT, BRAF, RB1 uye PTEN ndiwo mazita emhando yepamusoro anonzi Gliosarcoma. TP53 inoshumwa mu9.1% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye TERT inotaurwa mu9.1%. Huwandu hwehuwandu hwemurwere data inovhara makore kubva pa52 kusvika 80. 50.0 % yedata remurwere inozivikanwa sevarume. Iyo Gliosarcoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveGliosarcoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable CAULIFLOWER kana WELSH Hanyanisi?

Vegetable Cauliflower ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Lupeol, Delphinidin, Daidzein, Brassinin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seAngiogenesis, P53 Signaling, NFKB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Koliflower inokurudzirwa kuGliosarcoma apo chirwere chegomarara chiri kuramba chiri Temozolomide. Izvi zvinodaro nekuti Koliflower inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eTemozolomide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Welsh Onion ndeye Curcumin, Caffeine, Lupeol, Lycopene, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Welsh Onion haikurudzirwe kuGliosarcoma kana ichiramba ichirapwa kenza iri Temozolomide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MURIWO KAULIFLOWER INOKURURWA PAMUSORO PAMUSORO PEWELSH HANISI YEGliosarcoma UYE KURAPA Temozolomide.

Sarudza Muchero GRAPEFRUIT/PUMMELO HYBRID kana PUMMELO?

Chibereko Grapefruit/pummelo Hybrid ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seCurcumin, Apigenin, Caffeine, Lupeol, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, TGFB Signaling, NFKB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Grapefruit/pummelo Hybrid inokurudzirwa kuGliosarcoma apo chirwere chegomarara chiri kuramba chiri Temozolomide. Izvi zvinodaro nekuti Grapefruit/pummelo Hybrid inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeTemozolomide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Curcumin, Apigenin, Caffeine, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye TGFB Signaling nevamwe. Pummelo haikurudzirwe kuGliosarcoma kana ichiramba ichirapwa kenza iri Temozolomide nekuti inoshandura nzira dzebiochemical dziya dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUCHERO GRAPEFRUIT/PUMMELO HYBRID INOKURUDZWA PAMUSORO PEPUMMELO YEGliosarcoma UYE KURAPA Temozolomide.

Sarudza Nut BUTTERNUT kana PILI NUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Caffeine, Lupeol, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, MYC Signaling, NFKB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Butternut inokurudzirwa kuGliosarcoma apo chirwere chegomarara chiri kuramba chiri Temozolomide. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeTemozolomide.

Zvimwe zvezvinhu zvinoshanda kana bioactives muPili Nut ndeye Curcumin, Apigenin, Caffeine, Lupeol, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye TGFB Signaling nevamwe. Pili Nut haikurudzirwe kuGliosarcoma kana ichiramba ichirapwa kenza iri Temozolomide nekuti inogadzirisa nzira dzebiochemical idzo dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

BUTTERNUT INOKURUDZWA PAMUSORO PILI NUT YEGliosarcoma UYE KURAPA Temozolomide.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic njodzi yeGliosarcoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR or BLACK CABAGE?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge MAPK Kusaina, DNA Kugadzirisa, Stem Cell Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Giant Butterbur inokurudzirwa kune njodzi yeGliosarcoma kana yakabatana genetic njodzi iri BRAF. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Black Cabbage ndeye Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seOncogenic Cancer Epigenetics uye Stem Cell Signaling nevamwe. Black Cabbage haikurudzirwe kana njodzi yeGliosarcoma kana yakabatana nejeneki njodzi iri BRAF nekuti inowedzera siginicha nzira dzayo.

MURIWO MURUME BUTTERBUR ANOKURUKURIRWA PAMUSORO PAMUSORO MATEMA KABHAGE KUTI BRAF GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana ACEROLA?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge MAPK Kusaina, DNA Kugadzirisa, Stem Cell Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Nance inokurudzirwa kune njodzi yeGliosarcoma kana yakabatana genetic njodzi iri BRAF. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Acerola ndeye Apigenin, Curcumin, Quercetin, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seOncogenic Cancer Epigenetics uye Stem Cell Signaling nevamwe. Acerola haikurudzirwe kana njodzi yeGliosarcoma kana yakabatana genetic njodzi iri BRAF nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INAKURUDZIRWA PAMUSORO PEACEROLA YEBRAF GENETIC RISK YECANCER.

Sarudza Nut COMMON WALNUT kana EUROPEAN CHESTNUT?

Yakajairika Walnut ine akawanda anoshanda zvinhu kana bioactives seCurcumin, Quercetin, Ellagic Acid, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seMAPK Kusaina, DNA Kugadzirisa, Cell Cycle Checkpoints uye MYC Signaling nevamwe. Yakajairika Walnut inokurudzirwa kune njodzi yeGliosarcoma kana yakabatana genetic njodzi iri BRAF. Izvi zvinodaro nekuti Common Walnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Curcumin, Quercetin, Ellagic Acid, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye vamwe. European Chestnut haikurudzirwe kana njodzi yeGliosarcoma kana yakabatana genetic njodzi iri BRAF nekuti inowedzera siginecha nzira dzayo.

WALNUT YAKAWANDA INOKURUKURIRWA PAMUSORO PAEUROPA CHESTNUT YEBRAF GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seGliosarcoma. Varwere veGliosarcoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seGliosarcoma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seCauliflower chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Gliosarcoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Glioma Mskcc 2019
• Tumor mutational load inofanotaura kupona mushure me immunotherapy kune akawanda marudzi egomarara.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.
• Naringin inokurudzira masero egomarara reprostate kune paclitaxel kurapwa.
• Brassinin Yakasanganiswa neCapsaicin Inowedzera Apoptotic uye Anti-metastatic Effects muPC-3 Human Prostate Cancer Cells.
• Negative regulation ye signal transducer uye activator ye transcription-3 signing cascade ne lupeol inhibits kukura uye induces apoptosis muhepatocellular carcinoma masero.