Zvokudya zveGastric Adenocarcinoma!

ziviso

Zvikafu zveGastric Adenocarcinoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Gastric Adenocarcinoma, rudzi rwegomarara remudumbu, rinoratidzwa nemasero akaipa anoumba mukati memukati memudumbu, neiyo pathology rondedzero uye radiology ndiyo yakakosha mukuongororwa. Zviratidzo zvinogona kusanganisira kupera uremu, kurwadziwa nemudumbu, uye kusvotwa, kazhinji zvichitungamira kunonoka kuongororwa. The staging of gastric adenocarcinoma, kusanganisira nhanho 4, yakakosha pakuona kufungidzira uye nzira yekurapa. Metastasis inonyanya kunetseka, inokanganisa chiyero chekupona uye kutonga kwese kwechirwere. Iyo ICD-10 coding system inopa yakajairwa kupatsanurwa kwegastric adenocarcinoma, yakakosha kumarekodhi ekurapa uye tsvagiridzo. Kurapa kunosiyana kubva pakuvhiyiwa kuenda kuchemotherapy uye nemwaranzi, inotungamirwa nemirairo yekurapa uye nekukanganiswa nezvinhu zvakaita sebundu margin uye hutano hwemurwere. Gastric adenocarcinoma inoitikawo mumbwa, zvichiratidza kudiwa kwekuziva mukuchengetwa kwemhuka. Kunzwisisa zvinokonzeresa njodzi uye pathophysiology yegastric adenocarcinoma inogona kubatsira mukukurumidza kuona nekudzivirira, nekudya uye endoscopy kutamba mabasa mune ese ari maviri. Izwi rekuti 'gastric adenocarcinoma' rinowanzo shandiswa zvakasiyana negastric carcinoma, asi inomiririra masangano akasiyana mukati megomarara remudumbu, rimwe nerimwe richida kurapwa kwakaenderana uye nzira dzekutarisira.

Kune Gastric Adenocarcinoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seGastric Adenocarcinoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seGastric Adenocarcinoma?

Semuenzaniso zvine basa here kana muriwo weNew Zealand Sipinachi uchidyiwa zvakanyanya kana uchienzaniswa neWhite Cabbage? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane French Plantain? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peChestnut uye nemapuruzi akaita seGram Bean pamusoro peLima Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuGastric Adenocarcinoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neGastric Adenocarcinoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Pummelo ine zvinhu zvinoshanda zveQuercetin, Curcumin, Phloretin, Beta-sitosterol, Formononetin. Uye French Plantain ine zvinoshanda zvinosanganisa Quercetin, Myricetin, Curcumin, Phloretin, Beta-sitosterol uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheGastric Adenocarcinoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri mukudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yekudya kweGastric Adenocarcinoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Gastric Adenocarcinoma?

Kudya kwakasarudzika kwegomarara seGastric Adenocarcinoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muGastric Adenocarcinoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seGastric Adenocarcinoma

Ese magomarara seGastric Adenocarcinoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginicha nzira dzeGastric Adenocarcinoma. Nzira dzeBiochemical dzakadai seRAS-RAF Signaling, mRNA Splicing, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints chikamu chetsanangudzo yekusaina yeGastric Adenocarcinoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweGastric Adenocarcinoma kunofanirwa kuziva nezve siginecha yebiochemical nzira kune wese murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuGastric Adenocarcinoma kana uchitora kurapwa kwegomarara Radiation, uye zvimwe zvekudya nekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

TP53, ARID1A, CDH1, FAT4 neFAT3 ndiwo epamusoro akaverengerwa majini eGastric Adenocarcinoma. TP53 inoshumwa mu62.9% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye ARID1A inotaurwa mu18.6%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 69.2% yedata revarwere vanoonekwa sevarume. Iyo Gastric Adenocarcinoma biology pamwe neyakashumwa genetics pamwechete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveGastric Adenocarcinoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable NEW ZEALAND SPINACH kana WHITE CABAGE?

Vegetable New Zealand Sipinachi ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seQuercetin, Myricetin, Curcumin, Phloretin, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Microtubule Dynamics, Hypoxia, NFKB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. New Zealand Spinachi inokurudzirwa kuGastric Adenocarcinoma apo kurapwa gomarara kuri kuramba kuchiitwa Radiation. Izvi zvinodaro nekuti New Zealand Sipinachi inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo White Cabbage ndeye Quercetin, Curcumin, Phloretin, Beta-sitosterol, Benzyl Isothiocyanate. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seCytoskeletal Dynamics uye Oxidative Stress nevamwe. White Cabbage haikurudzirwe kune Gastric Adenocarcinoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MURIWO NEW ZEALAND SIPICHI INOKURUDZWA PAMUSORO RACHENA KABHCHI YEGastric Adenocarcinoma UYE KURAPA Radiation.

Sarudza Fruit FRENCH PLANTAIN kana PUMMELO?

Chibereko cheFrench Plantain chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Myricetin, Curcumin, Phloretin, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Microtubule Dynamics, Hypoxia, NFKB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. French Plantain inokurudzirwa kuGastric Adenocarcinoma kana kurapa gomarara kuri kuramba kuchiitwa Radiation. Izvi zvinodaro nekuti French Plantain inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Curcumin, Phloretin, Beta-sitosterol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Heat Stress Response uye Oxidative Stress nevamwe. Pummelo haikurudzirwe kuGastric Adenocarcinoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

FRUIT FRENCH PLANTAIN INOKURUDZWA PAMUSORO PEPUMMELO YEGastric Adenocarcinoma NEKURAPA Radiation.

Sarudza Nut BUTTERNUT kana CHESTNUT?

Butternut ine zvinhu zvakawanda zvinoshanda kana bioactives seMyricetin, Curcumin, Phloretin, Beta-sitosterol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical senge Microtubule Dynamics, DNA Repair, NFKB Signaling uye MAPK Signaling nevamwe. Butternut inokurudzirwa kuGastric Adenocarcinoma kana chirwere chegomarara chiri kuramba chiri cheRadiation. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Ellagic Acid, Myricetin, Curcumin, Phloretin, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Heat Stress Response, Stem Cell Signaling uye Oxidative Stress nevamwe. Chestnut haikurudzirwe kuGastric Adenocarcinoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

BUTTERNUT INOKURUDZWA PAMUSORO PACHESTNUT YEGastric Adenocarcinoma UYE KURAPA Radiation.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeGastric Adenocarcinoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable COMMON USHROOM kana CHAYOTE?

Vegetable Common Mushroom ine akawanda anoshanda zvinhu kana bioactives akadai Vitamin D3, Apigenin, Curcumin, Lupeol, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, Hypoxia uye PI3K-AKT-MTOR Signaling nevamwe. Common Mushroom inokurudzirwa kune njodzi yeGastric Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Common Mushroom inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuriwo Chayote ndeye Apigenin, Curcumin, Lupeol, Phloretin, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Signaling, TGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Chayote haikurudzirwe kana njodzi yeGastric Adenocarcinoma kana yakabatana nejeneki njodzi iri ARID1A nekuti inowedzera siginicha nzira dzayo.

MURIWO WAKAWANZWA MUSHROOM INOKURUDZWA PAMUSORO PECHAYOTE KUTI ARID1A GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana JUJUBE?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Phloretin, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, Hypoxia uye PI3K-AKT-MTOR Signaling nevamwe. Nance inokurudzirwa panjodzi yeGastric Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Jujube ndeye Apigenin, Curcumin, Quercetin, Lupeol, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Signaling, TGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Jujube haikurudzirwe kana njodzi yeGastric Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A nekuti inowedzera siginicha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PEJUJUBE KUTI ARID1A GENETIC RISK YECANCER.

Sarudza Nut COMMON WALNUT kana EUROPEAN CHESTNUT?

Yakajairika Walnut ine akawanda anoshanda zvinhu kana bioactives seCurcumin, Quercetin, Lupeol, Ellagic Acid, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Kusaina, Hypoxia, MYC Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Common Walnut inokurudzirwa kune njodzi yeGastric Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Common Walnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Curcumin, Quercetin, Lupeol, Ellagic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling, TGFB Signaling uye Stem Cell Signaling nevamwe. European Chestnut haikurudzirwe kana njodzi yeGastric Adenocarcinoma kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

WALNUT YAKAWANDA INOKURUDZWA PAMUSORO PEEUROPA CHESTNUT YEARID1A GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune cancer seGastric Adenocarcinoma. Varwere veGastric Adenocarcinoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seGastric Adenocarcinoma, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega senge New Zealand Sipinachi ine akasiyana bioactive muhuwandu hwakasiyana, iyo ine mhedzisiro pane dzakasiyana uye dzakasiyana seti dzebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Gastric Adenocarcinoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Pan Yakatangwa 2020
• DNA kugadzirisa uye redox zviitiko uye inhibitors yeapurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): kuongororwa kwekuenzanisa uye chiyero chavo uye zvisingakwanisi kune anticancer drug development.
• Iyo citrus flavonoid naringenin inokurudzira DNA kugadziriswa mumasero ekenza yeprostate.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.
• Functional lipidomics: Palmitic acid inokanganisa hepatocellular carcinoma kukura nekugadzirisa membrane fluidity uye glucose metabolism.
• https://my.clevelandclinic.org/health/diseases/15812-stomach-cancer
• https://www.ncbi.nlm.nih.gov/books/NBK459142/
• https://emedicine.medscape.com/article/278744-overview