Zvokudya zveErdheim Chester Chirwere!

ziviso

Zvikafu zveErdheim Chester Chirwere zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Chirwere cheErdheim-Chester (ECD) chisingaperi, chisiri cheLangerhans cell histiocytosis, chinowanzoonekwa segomarara, nechikonzero chayo chiri kuongororwa asi chisingawanzo kutorwa senhaka kana genetic. Inoratidzwa nezviratidzo zvakasiyana sekurwadziwa kwebhonzo uye kuratidzwa kwetsinga, ECD kuongororwa kunosanganisira musanganiswa wemaitiro eradiological, anosanganisira CT uye uropi MRI, uye yakazara pathology rondedzero. Matanho ekurapa Erdheim-Chester Chirwere ari kuramba achibuda, aine ruzivo rwakagadziridzwa rwunowanikwa kuburikidza nemapuratifomu seUpToDate uye Erdheim-Chester Chirwere Global Alliance. ECD inowanzobatanidza masisitimu enhengo semapapu nehuropi, uye radiology yakakosha pakuongorora chirwere uye kutarisa. Yakarongerwa pasi peICD-10 system, hutungamiri hweECD hunovhenekerwa kuburikidza nekuongorora uye zvidzidzo zvezviitiko, zvichiratidza kukosha kwekuenderera mberi kwekutsvakurudza uye kuziva mukugadzirisa chirwere ichi chakaoma.

Kune Erdheim Chester Chirwere zvine basa kuti miriwo, michero, nzungu, mhodzi anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - yegomarara senge Erdheim Chester Chirwere zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza senge Erdheim Chester Chirwere?

Semuyenzaniso zvine basa here kana muriwo Eggplant uchidyiwa zvakanyanya zvichienzaniswa neChayote? Zvinoita mutsauko here kana muchero Shuga Apple uchisarudzwa kupfuura Arctic Blackberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seBlack Walnut pamusoro peMacadamia Nut uye nemapuruzi akaita seGreen Bean pamusoro peCatjang Pea. Uye kana izvo zvandinodya zvine basa - zvino munhu anoona sei zvikafu zvinokurudzirwa Erdheim Chester Chirwere uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neErdheim Chester Chirwere!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Shuwa Apple ine zvinhu zvinoshanda Myricetin, Lycopene, Pelargonidin, Curcumin, Cinnamaldehyde. Uye Arctic Blackberry ine zvinoshanda zvinosanganisa Ellagic Acid, Lycopene, Curcumin, Quercetin, Cinnamaldehyde uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheErdheim Chester Chirwere - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone cherry kutora zvinoshanda muzvikafu uye zvinowedzera kuita sarudzo yehutano hweErdheim Chester Chirwere.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi Hunodiwa Kuti Uve Nekudya Kwemunhu Kwechirwere cheErdheim Chester?

Kudya kwakasarudzika kwegomarara senge Erdheim Chester Chirwere chine chikafu chinokurudzirwa / ma supplements; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muErdheim Chester Chirwere biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Erdheim Chester Chirwere

Ese cancers senge Erdheim Chester Chirwere inogona kuratidzwa neyakasiyana seti ye biochemical nzira - iyo siginecha nzira dzeErdheim Chester Chirwere. Biochemical nzira dzakadai seRAS-RAF Chiratidzo, MAPK Chiratidzo, Cytoskeletal Dynamics, Angiogenesis chikamu chetsanangudzo yekusaina yeErdheim Chester Chirwere. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kuErdheim Chester Chirwere kunofanirwa kuziva nzira dzakasaina dzebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemagene. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuErdheim Chester Chirwere kana uchitora kurapwa kenza Vemurafenib, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

MAP2K1, ARAF, ARID5B, BRAF neMYCN ndiwo mazita emajini akashumwa epamusoro eErdheim Chester Disease. MAP2K1 inoshumwa mu25.0% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye ARAF inoshumwa mu12.5%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 61.5% yedata revarwere vanoonekwa sevarume. Iyo Erdheim Chester Chirwere biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveErdheim Chester Chirwere

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable EGGPLANT kana CHAYOTE?

Vegetable Eggplant ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seMyricetin, Isorhamnetin, Gallic Acid, Curcumin, Quercetin. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling, RAS-RAF Signaling uye MAPK Signaling nevamwe. Eggplant inokurudzirwa kuErdheim Chester Chirwere kana ichiramba ichirapwa cancer iri Vemurafenib. Izvi zvinodaro nekuti Eggplant inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eVemurafenib.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Chayote ndeyeMyricetin, Pelargonidin, Curcumin, Cinnamaldehyde, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seWNT Beta Catenin Signaling uye MAPK Signaling nevamwe. Chayote haikurudzirwe kune Erdheim Chester Chirwere kana ichienderera mberi kurapwa kwegomarara iri Vemurafenib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MAZAI EMRIWO INOKURUDZWA PAMUSORO PECHAYOTE KUNE Erdheim Chester Chirwere NEKURAPA Vemurafenib.

Sarudza Muchero ARCTIC BLACKBERRY kana SUGAR APPLE?

Chibereko Arctic Blackberry ine akawanda anoshanda zvinosanganisa kana bioactives seEllagic Acid, Lycopene, Curcumin, Quercetin, Cinnamaldehyde. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling, RAS-RAF Signaling uye MAPK Signaling nevamwe. Arctic Blackberry inokurudzirwa kuErdheim Chester Chirwere kana ichiramba ichirapwa cancer iri Vemurafenib. Izvi zvinodaro nekuti Arctic Blackberry inogadziridza nzira dziya dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kushanda kweVemurafenib.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Shuga Apple ndeyeMyricetin, Lycopene, Pelargonidin, Curcumin, Cinnamaldehyde. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling nevamwe. Shuga Apple haikurudzirwe kune Erdheim Chester Chirwere kana ichienderera mberi kurapwa kwegomarara iri Vemurafenib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUCHERO ARCTIC BLACKBERRY INOKURURWA PAMUSORO PAMUSORO PESUGA Apuro KUNE Erdheim Chester Chirwere UYE KURAPA Vemurafenib.

Sarudza Nut BLACK WALNUT kana MACADAMIA NUT?

Black Walnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seMyricetin, Ellagic Acid, Pelargonidin, Gallic Acid, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge RAS-RAF Signaling uye MAPK Signaling nevamwe. Black Walnut inokurudzirwa kuErdheim Chester Disease apo chirwere chegomarara chiri kuramba chiri Vemurafenib. Izvi zvinodaro nekuti Black Walnut inogadziridza nzira dziya dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eVemurafenib.

Zvimwe zvezvinhu zvinoshanda kana bioactives muMacadamia Nut ndeyeMyricetin, Pelargonidin, Curcumin, Cinnamaldehyde, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seWNT Beta Catenin Signaling uye MAPK Signaling nevamwe. Macadamia Nut haikurudzirwe kune Erdheim Chester Chirwere kana ichienderera mberi kurapwa kwegomarara iri Vemurafenib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

BLACK WALNUT INOKURUDZWA PAMUSORO PEMACADAMIA NUT KUNE Erdheim Chester Chirwere UYE KURAPA Vemurafenib.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic njodzi yeErdheim Chester Chirwere kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana GARLAND CHRYSANTHEMUM?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Myricetin, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seAngiogenesis, RAS-RAF Signaling, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Garland Chrysanthemum ndeye Apigenin, Curcumin, Myricetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling uye MAPK Signaling nevamwe. Garland Chrysanthemum haikurudzirwe kana njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF nekuti inowedzera siginecha nzira dzayo.

MURIWO MURUME BUTTERBUR ANOKURUKURWA PAMUSORO PAGARLAND CHRYSANTHEMUM YEARAF GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana PUMMELO?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Myricetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seAngiogenesis, RAS-RAF Signaling, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Nance inokurudzirwa kune njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Quercetin, Lycopene, Lupeol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling uye Cell Cycle Checkpoints nevamwe. Pummelo haikurudzirwe kana njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INAKURUDZIRWA PAMUSORO PAMUSORO PAMUSORO PAMUSORO PE ARAF GENETIC RISK OF CANCER.

Sarudza Nut COMMON HAZELNUT kana EUROPEAN CHESTNUT?

Common Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Quercetin, Myricetin, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Angiogenesis, RAS-RAF Signaling, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Ellagic Acid, Curcumin, Quercetin, Myricetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seWNT Beta Catenin Signaling, PI3K-AKT-MTOR Kuratidzira uye MYC Kunongedza nevamwe. European Chestnut haikurudzirwe kana njodzi yeErdheim Chester Chirwere kana yakabatana genetic njodzi iri ARAF nekuti inowedzera siginecha nzira dzayo.

COMMON HAZELNUT INOKURUDZWA PAMUSORO PEEUROPA CHESTNUT YEARAF GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara senge Erdheim Chester Chirwere. Varwere veErdheim Chester Chirwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Erdheim Chester Chirwere, imwe neimwe iine tumor genetics ine mamwe ma genomic akasiyana kune mumwe nemumwe. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega senge Eggplant chine akasiyana bioactive muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Erdheim Chester Chirwere?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Retinol inoderedza beta-catenin mapuroteni mazinga mu retinoic acid-inodzivirira colon cancer cell mitsara.
• Geraniol, chikamu chezvirimwa zvakakosha oiri, inosimudzira masero egomarara revanhu ku5-Fluorouracil kurapwa.
• Chemoprevention ye intestinal tumorigenesis neyakasikwa chikafu flavonoid myricetin mu APCMin/+ mice.
• Dziviriro inopesana nekusimudzira mhedzisiro yeti chena uye caffeine paPhIP-induced tumorigenesis uye beta-catenin kutaura mugonzo.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.
• https://medlineplus.gov/genetics/condition/erdheim-chester-disease/#resources
• https://rarediseases.org/rare-diseases/erdheim-chester-disease
• https://histio.org/histiocytic-disorders/erdheim-chester-disease
• https://www.lls.org/sites/default/files/2022-07/FS37_Erdheim_Chester_2022.pdf