Zvokudya zveEpithelioid Sarcoma!

ziviso

Zvokudya zveEpithelioid Sarcoma zvinofanirwa kuve zvakasarudzika kune mumwe nemumwe uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

epithelioid sarcoma ishoma, inononoka kukura yekenza yakapfava, inowanzoonekwa pasi peganda remunwe, ruoko, forearm, gumbo rezasi kana tsoka. Iyi sarcoma yakapfava iyi inowanzoonekwa muvarume uye inobata vechidiki vechidiki mumakore avo makumi maviri. Pakutanga idiki, kukura kwakasimba kana bundu risingarwadzi. Dzimwe nguva, epithelioid sarcoma inoratidzika semaronda uye maronda akazaruka pamusoro pezvinomera, izvo zvisingapore. Epithelioid sarcoma inogona kuva nehuwandu hwekudzokazve kusvika ku20% uye inogona kupararira kune dzimwe nzvimbo dzemuviri. Muchidzidzo chenguva refu, 77% yevarwere vane epithelioid sarcoma vakagadzira metastatic chirwere, nemapapu, lymph nodes, ganda remusoro richiva nzvimbo dzinonyanya kupararira. Iyo inonyanya kukurudzirwa nzira yekurapa epithelioid sarcoma ndeye yakakura yekuvhiya resection. Gender, sarcoma sarcoma, zera rekuongororwa, saizi yebundu uye microscopic pathology zvakaratidzwa zvichikanganisa kufungidzira kwe epithelioid sarcoma. Mabundu aripo pazera rekutanga aive nemhedzisiro iri nani. Bonde remurume, saizi yebundu inodarika 45 cm, proximal multifocal tumors, uye kuvapo kwevascular invesion mumuenzaniso webiopsy zvine hukama nemhedzisiro yakaipa yekiriniki. Kuchengeta kunotsigira nekudya kwakakodzera (zvekudya uye zvechisikigo zvekuwedzera) zvinogona kuvandudza kugara kwemurwere.

Kune Epithelioid Sarcoma zvine basa here kuti miriwo, michero, nzungu, mhodzi anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seEpithelioid Sarcoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seEpithelioid Sarcoma?

Semuenzaniso zvine basa here kana muriwo weParsnip uchidyiwa zvakanyanya kana uchienzaniswa neBlack Cabbage? Zvinoita mutsauko here kana muchero Babassu Palm uchisarudzwa pane Lemon? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seAlmond pamusoro peEuropean Chestnut uye yemapurusi seBlack-eyed Pea pamusoro peCommon Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa Epithelioid Sarcoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic ngozi?

Ehe! Zvokudya zvaunodya zvine chekuita neEpithelioid Sarcoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Babassu Palm ine zvinhu zvinoshanda Myricetin, Protocatechuic Acid, Curcumin, Daidzein, Lupeol. Uye Lemon ine zvinoshanda zvinosanganisa D-limonene, Caffeine, Linalool, Protocatechuic Acid, Diosmetin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheEpithelioid Sarcoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweEpithelioid Sarcoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Epithelioid Sarcoma?

Kudya kwakasarudzika kwegomarara senge Epithelioid Sarcoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muEpithelioid Sarcoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Epithelioid Sarcoma

Magomarara ese akaita seEpithelioid Sarcoma anogona kuratidzirwa neyakasiyana seti ye biochemical nzira - masiginecha nzira dzeEpithelioid Sarcoma. Nzira dzeBiochemical dzakadai seDNA Repair, MAPK Signaling, PI3K-AKT-MTOR Signaling, Chromatin Remodeling chikamu chetsanangudzo yechiratidzo cheEpithelioid Sarcoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweEpithelioid Sarcoma kunoda kuziva nezve siginecha yebiochemical nzira kune wese murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa Epithelioid Sarcoma kana uchitora cancer kurapwa Etoposide, uye zvimwe zvekudya nekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

SMARCB1, CDKN2C, FAT1, KMT2C uye ABL1 ndiwo emhando yepamusoro akashumwa majini eEpithelioid Sarcoma. SMARCB1 inoshumwa mu12.5% ​​yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye CDKN2C inoshumwa mu6.2%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 53.3% yedata revarwere vanoonekwa sevarume. Iyo Epithelioid Sarcoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveEpithelioid Sarcoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable PASNIP kana BLACK CABAGE?

Vegetable Parsnip ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seProtocatechuic Acid, Quercetin, Gallic Acid, Curcumin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical sePI3K-AKT-MTOR Signaling, DNA Repair uye MAPK Signaling nevamwe. Parsnip inokurudzirwa kuEpithelioid Sarcoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Parsnip inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Black Cabbage ndeyeMyricetin, Protocatechuic Acid, Curcumin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye MAPK Signaling nevamwe. Black Cabbage haikurudzirwe kuEpithelioid Sarcoma kana ichiramba ichirapwa gomarara iri Etoposide nekuti inogadzirisa dziya dzebiochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

VEGETABLE PARSNIP INOKURUDZWA PAMUSORO PAMUSORO MATEMA KABHAGE KUNE Epithelioid Sarcoma UYE KURAPA Etoposide.

Sarudza Muchero LEMON kana BABASSU PALM?

Chibereko Lemon ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seD-limonene, Caffeine, Linalool, Protocatechuic Acid, Diosmetin. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira uye MAPK Kusaina uye vamwe. Lemon inokurudzirwa kuEpithelioid Sarcoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Lemon inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Babassu Palm ndeyeMyricetin, Protocatechuic Acid, Curcumin, Daidzein, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. Babassu Palm haikurudzirwe Epithelioid Sarcoma kana ichiramba ichirapwa cancer iri Etoposide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO LEMON INOKURUDZWA PAMUSORO PABABASSU PALM YEEpithelioid Sarcoma UYE KURAPA Etoposide.

Sarudza Nut ALMOND kana EUROPEAN CHESTNUT?

Almond ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Daidzein, Lupeol, Umbelferone, Cinnamaldehyde. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical sePI3K-AKT-MTOR Signaling, MAPK Signaling uye MYC Signaling nevamwe. Almond inokurudzirwa kuEpithelioid Sarcoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Almond inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeyeMyricetin, Protocatechuic Acid, Ellagic Acid, Quercetin, Gallic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. European Chestnut haikurudzirwe kuEpithelioid Sarcoma kana ichiramba ichirapwa kenza iri Etoposide nekuti inogadzirisa nzira dzebiochemical dziya dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

ALMOND INOKURUKURWA PAKATI PAEUROPA CHESTNUT YEEpithelioid Sarcoma UYE KURAPA Etoposide.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeEpithelioid Sarcoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana AMERICAN POKEWEED?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seRAS-RAF Chiratidzo, Cell Cycle, PI3K-AKT-MTOR Signaling uye Oncogenic Cancer Epigenetics nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo weAmerican Pokeweed ndewe Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. American Pokeweed haikurudzirwe kana njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1 nekuti inowedzera siginicha nzira dzayo.

MURIWO MURUME BUTTERBUR INOKURUKURWA PAMUSORO PEAMERICAN POKEWEED YEABL1 GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana PUMMELO?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seRAS-RAF Chiratidzo, Cell Cycle, PI3K-AKT-MTOR Signaling uye Oncogenic Cancer Epigenetics nevamwe. Nance inokurudzirwa kune njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. Pummelo haikurudzirwe kana njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1 nekuti inowedzera siginicha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PE ABL1 GENETIC RISK YECANCER.

Sarudza Nut COMMON HAZELNUT kana CHESTNUT?

Common Hazelnut ine akawanda anoshanda zvinhu kana bioactives akadai Curcumin, Lupeol, Daidzein, Beta-sitosterol, Quercetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seSero Cycle, PI3K-AKT-MTOR Signaling, Growth Factor Signaling uye Apoptosis nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Curcumin, Lupeol, Ellagic Acid, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. Chestnut haikurudzirwe kana njodzi yeEpithelioid Sarcoma kana njodzi yemajini yakabatana iri ABL1 nekuti inowedzera siginicha nzira dzayo.

COMMON HAZELNUT INOKUDZWA PAMUSORO PACHESTNUT YEABL1 GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seEpithelioid Sarcoma. Epithelioid Sarcoma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Epithelioid Sarcoma, imwe neimwe iine bundu genetics ine mamwe majenomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seParsnip chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudza Epithelioid Sarcoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Pan Yakatangwa 2020
• D-Limonene inogadzirisa kuzvimba, oxidative kusagadzikana uye Ras-ERK nzira yekudzivisa murine ganda tumorigenesis.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.
• Imperatorin inodzvinyirira kuwanda uye angiogenesis yekenza yegomarara remunhu nekutarisa HIF-1α kuburikidza nemTOR/p70S6K/4E-BP1 uye MAPK nzira.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.
• Paederia foetida induces anticancer chiitiko nekugadzirisa chromatin modification enzymes uye kushandura pro-inflammatory cytokine gene kutaura mumunhu masero ekenza yeprostate.
• Gallic acid inomutsa kukuvara kweDNA uye inodzvanya DNA kugadzirisa gene kutaura mukenza yeprostate yemunhu PC-3 masero.
• https://sarcomahelp.org/epithelioid-sarcoma.html#:~:text=Epithelioid%20sarcoma%20is%20a%20rare%20sarcoma%20that%20affects%20young%20adults,and%20spread%20along%20lymphatic%20channels.; https://www.ncbi.nlm.nih.gov/books/NBK532911
• https://www.mayoclinic.org/diseases-conditions/epithelioid-sarcoma/cdc-20392420