Zvokudya zveMaromo uye Oral Cavity Cancer!

ziviso

Chikafu cheMuromo Uye Oral Cavity Cancer inofanirwa kuve yakasarudzika kune yega yega uye zvakare inofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Zveremuromo uye Oral Cavity Cancer zvine basa here kuti miriwo, michero, nzungu, mhodzi anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - yegomarara senge Lip And Oral Cavity Cancer zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seLip Uye Oral Cavity Cancer?

Semuenzaniso zvine basa here kana muriwo Wemusango Carrot uchidyiwa zvakanyanya uchienzaniswa neJerusarema Artichoke? Pane mutsauko here kana muchero Medlar uchifarirwa pane Watermelon? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peEuropean Chestnut uye yemapurusi seAdzuki Bean pamusoro peMung Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu anoona sei zvikafu zvinokurudzirwa kuLip Uye Oral Cavity Cancer uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neLip Uye Oral Cavity Cancer!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuyenzaniso Medlar ine zvinoshanda zvinosanganisa Apigenin, Curcumin, Catechol, Lupeol, Caffeine. Uye Watermelon ine zvinoshanda zvinosanganisa Curcumin, Catechol, Lupeol, Daidzein, Beta-sitosterol uye pamwe nevamwe.

Chikanganiso chakajairika pakusarudza nekusarudza chikafu chekudya cheLip And Oral Cavity Cancer - ndeyekuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone cherry kutora zvinoshanda muzvikafu uye ma supplements ekuita sarudzo yehutano yeLip Uye Oral Cavity Cancer.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi Hunodiwa Kuti Uve Nekudya Kwemunhu Kwemiromo Uye Oral Cavity Cancer?

Kudya kwakasarudzika kwekenza senge Lip Uye Oral Cavity Cancer ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muLip Uye Oral Cavity Cancer biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Lip Uye Oral Cavity Cancer

Magomarara ese akaita seLip Uye Oral Cavity Cancer anogona kuratidzwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeLip Uye Oral Cavity Cancer. Nzira dzeBiochemical dzakadai seApoptosis, Chromatin Remodeling, Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling chikamu chetsanangudzo yeSiginecha yeLip Uye Oral Cavity Cancer. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Iwo marapirwo anoshanda kune Lip Uye Oral Cavity Cancer inofanirwa kuziva iyo inosanganisirwa siginecha yebiochemical nzira kune wega wega cancer murwere uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuLip Uye Oral Cavity Cancer kana uchitora kurapwa kwegomarara Trabectedin, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

TP53, TERT, CDKN2A, NOTCH1 uye PIK3CA ndiwo mazita epamusoro akataurwa majini eLip Uye Oral Cavity Cancer. TP53 inoshumwa mu34.4% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye TERT inoshumwa mu32.0%. Huwandu hwehuwandu hwemurwere data inovhara makore kubva pa26 kusvika 99. 71.0 % yedata remurwere inozivikanwa sevarume. Iyo Lip And Oral Cavity Cancer biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveLip Uye Oral Cavity Cancer

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable WILD CARROT kana JERUSALEM ARTICHOKE?

Vegetable Wild Carrot ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Quercetin, Curcumin, Catechol, Lupeol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seSero Cycle, MYC Signaling, NFKB Signaling uye Cell Survival nevamwe. Wild Carrot inokurudzirwa kuLip And Oral Cavity Cancer kana ichiramba ichirapwa gomarara iri Trabectedin. Izvi zvinodaro nekuti Wild Carrot inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eTrabectedin.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuriwo weJerusarema Artichoke ndiwo Apigenin, Curcumin, Catechol, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Jerusalem Artichoke haina kukurudzirwa kuLip Uye Oral Cavity Cancer kana ichienderera mberi kurapwa kwegomarara iri Trabectedin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MURIWO WAKAROTI WAKAROTI INOKURUDZWA PAMUSORO PEJERUSAREMA ARTICHOKE YEMBERO NEOral Cavity Cancer NEKURAPA Trabectedin.

Sarudza Muchero WATERMELON kana MEDLAR?

Chibereko Watermelon ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Catechol, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Hypoxia uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Watermelon inokurudzirwa kuLip And Oral Cavity Cancer kana ichiramba ichirapwa gomarara iri Trabectedin. Izvi zvinodaro nekuti Watermelon inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eTrabectedin.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Medlar ndeye Apigenin, Curcumin, Catechol, Lupeol, Caffeine. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seDNA Repair uye Angiogenesis nevamwe. Medlar haikurudzirwe kune Lip Uye Oral Cavity Cancer kana ichienderera mberi kurapwa kwegomarara iri Trabectedin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

FRUIT WATERMELON INOKURUKUDZWA PAMUSORO PEMEDLAR YEMUPENDO NEOral Cavity Cancer UYE KURAPA Trabectedin.

Sarudza Nut BUTTERNUT kana EUROPEAN CHESTNUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Catechol, Lupeol, Caffeine. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seDNA Kugadzirisa, Hypoxia, NFKB Kuratidzira uye Angiogenesis nevamwe. Butternut inokurudzirwa kuLip And Oral Cavity Cancer kana ichiramba ichirapwa gomarara iri Trabectedin. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eTrabectedin.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Quercetin, Curcumin, Catechol, Ellagic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. European Chestnut haikurudzirwe kuLip Uye Oral Cavity Cancer kana ichienderera mberi kurapwa kwegomarara iri Trabectedin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

BUTTERNUT INOKURUKUDZWA PAMUSORO PEEUROPA CHESTNUT YEMiromo uye Oral Cavity Gomarara UYE KURAPA Trabectedin.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeLip And Oral Cavity Cancer kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable YELLOW ZUCCHINI kana LETTUCE?

Vegetable Yellow Zucchini ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, Insulin Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Yellow Zucchini inokurudzirwa kune njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A. Izvi zvinodaro nekuti Yellow Zucchini inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Lettuce ndeye Curcumin, Quercetin, Lupeol, Vitamin D3, Formononetin. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana-siyana dzebiochemical seMAPK Signaling uye PI3K-AKT-MTOR Signaling uye vamwe. Lettuce haina kukurudzirwa kana njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A nekuti inowedzera siginecha nzira dzayo.

MURIWO WEYELLOW ZUCCHINI UNAKURUDZIRWA PAMUSORO PE LETTUCE YECDKN2A GENETIC RISK YECANCER.

Sarudza Muchero JAVA PLUM kana PUMMELO?

Chibereko Java Plum ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Ellagic Acid, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical senge MAPK Signaling, MYC Signaling, Angiogenesis uye PI3K-AKT-MTOR Signaling nevamwe. Java Plum inokurudzirwa kune njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A. Izvi zvinodaro nekuti Java Plum inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Quercetin, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seSero Cycle Checkpoints uye Insulin Signaling nevamwe. Pummelo haina kukurudzirwa kana njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A nekuti inowedzera siginecha nzira dzayo.

FRUIT JAVA PLUM INAKURUDZIRWA PAMUSORO PEPUMMELO YECDKN2A GENETIC RISK YECANCER.

Sarudza Nut COMMON WALNUT kana CHESTNUT?

Yakajairika Walnut ine akawanda anoshanda zvinhu kana bioactives seCurcumin, Quercetin, Lupeol, Ellagic Acid, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, Insulin Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Yakajairika Walnut inokurudzirwa kune njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A. Izvi zvinodaro nekuti Common Walnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Curcumin, Lupeol, Ellagic Acid, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle Checkpoints, Stem Cell Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Chestnut haikurudzirwe kana njodzi yeLip Uye Oral Cavity Cancer kana yakabatana genetic njodzi iri CDKN2A nekuti inowedzera siginecha nzira dzayo.

WALNUT YAkajairika INOKURUKURWA PAMUSORO PACHESTNUT YECDKN2A GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seLip Uye Oral Cavity Cancer. Lip And Oral Cavity Cancer varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Lip Uye Oral Cavity Cancer, imwe neimwe iine akasiyana bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega senge Wild Carrot ine akasiyana bioactive muhuwandu hwakasiyana, iyo ine mhedzisiro pane dzakasiyana uye dzakasiyana seti dzebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudza zveLip Uye Oral Cavity Cancer?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Yakasanganiswa Allen 2018
• Pan-cancer kuongororwa kweiyo genomes yakazara.
• Iyo antitumor mhedzisiro yegeraniol: Modulation yegomarara hallmark nzira (Ongororo).
• Negative regulation ye signal transducer uye activator ye transcription-3 signing cascade ne lupeol inhibits kukura uye induces apoptosis muhepatocellular carcinoma masero.
• Betulinic acid inhibisa kenza yeprostate kukura kuburikidza nekudzivirirwa kweiyo chaiyo protein transcription factor.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.