Zvokudya zveLeiomyosarcoma!

ziviso

Zvikafu zveLeiomyosarcoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Leiomyosarcoma igomarara risingawanzo gadzira munyama isina kugadzikana yakatsetseka inowanikwa munzvimbo dzakasiyana dzemuviri kusanganisira dumbu, dundira, chibereko, matumbu, uye tsinga dzeropa. Iaggressive soft tissue sarcoma inowanzoitika muvakadzi kupfuura varume, uye inowanzoitika kune vanhu vakuru vanopfuura makore makumi mashanu. zviratidzo zvinosanganisira kurwadziwa, kuneta, kuzvimba kwedumbu, kuda kurutsa uye kurutsa, kupera muviri uye fivha. Leiomyosarcoma ine mwero wepamusoro wekupararira kune chero nyama yakapfava mumuviri kusanganisira mapapu. Kana leiomyosarcoma ichionekwa mumatanho ekutanga uye yabviswa nekuvhiyiwa, ine fungidziro yakanaka uye kupora kuzere kunogona kuitika. Zvisinei, kana leiomyosarcoma yakakura uye ine metastasized kune dzimwe nhengo dzemuviri, kurapwa kunonyanya kuoma uye ine fungidziro yakaipa. Nzira dzekurapa leiomyosarcoma dzinosanganisira kuvhiyiwa, radiation therapy, uye chemotherapy. Kutsigira kutsigirwa nekudya kwakakodzera (zvekudya uye zvechisikigo zvekuwedzera) pamwe nekurapa zvinogona kuvandudza hutano hwemurwere.

Kune Leiomyosarcoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kugomarara senge Leiomyosarcoma zvine basa kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seLeiomyosarcoma?

Semuenzaniso zvine basa here kana muriwo Giant Butterbur ukadyiwa zvakanyanya uchienzaniswa neMalabar Spinachi? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seCommon Walnut pamusoro peChestnut uye nemapuruzi akaita seBroad Bean pamusoro peChickpea. Uye kana izvo zvandinodya zvine basa - zvino munhu anoona sei chikafu chinokurudzirwa Leiomyosarcoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neLeiomyosarcoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Curcumin, Caffeic Acid, Phloretin, Catechol. Uye Red Raspberry ine zvinoshanda zvinosanganisa Quercetin, Ellagic Acid, Curcumin, Phloretin, Catechol uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheLeiomyosarcoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yekudya kune Leiomyosarcoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Leiomyosarcoma?

Kudya kwakasarudzika kwegomarara senge Leiomyosarcoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muLeiomyosarcoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Leiomyosarcoma

Ese magomarara seLeiomyosarcoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - siginecha nzira dzeLeiomyosarcoma. Biochemical nzira seAngiogenesis, PI3K-AKT-MTOR Chiratidzo, Diki Molecule Yekutakura, Focal Adhesion chikamu cheiyo siginecha tsananguro yeLeiomyosarcoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kuLeiomyosarcoma kunoda kuziva nzira dzakasaina dzebiochemical dzemurwere wega wega wegomarara uye munhu ari panjodzi yemagene. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuLeiomyosarcoma kana uchitora kurapwa kenza Fluorouracil, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

RB1, PTEN, RYR2, MT-CO1 uye MAP2 ndiwo mazita epamusoro akashumwa majini eLeiomyosarcoma. RB1 inoshumwa mu 3.7% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye PTEN inoshumwa mu1.4%. Huwandu hwehuwandu hwemurwere data inovhara makore kubva pa33 kusvika 90. 36.7 % yedata remurwere inozivikanwa sevarume. Iyo Leiomyosarcoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririra siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer bundu genetics kana majini anokonzera njodzi achizivikanwa zvakare saka izvo zvinofanirwa kushandiswawo kune chikafu chemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveLeiomyosarcoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable GIANT BUTTERBUR kana MALABAR SPINACH?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Caffeic Acid, Phloretin, Catechol, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge MAPK Signaling, DNA Repair, Adherens junction uye Microtubule Dynamics nevamwe. Giant Butterbur inokurudzirwa kuLeiomyosarcoma apo chirwere chegomarara chiri kuramba chiri Fluorouracil. Izvi zvinodaro nekuti Giant Butterbur inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mhedzisiro yeFluorouracil.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Malabar Sipinachi ndeye Quercetin, Curcumin, Caffeic Acid, Phloretin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNucleotide metabolism, NFKB Signaling uye Oxidative Stress nevamwe. Malabar Sipinachi haikurudzirwe kuLeiomyosarcoma kana ichiramba ichirapwa cancer iri Fluorouracil nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MURIWO MURUME BUTTERBUR ANOKURUKURWA PAMUSORO PAMALABAR SPINACH YELeiomyosarcoma UYE KURAPA Fluorouracil.

Sarudza Muchero RED RASPBERRY kana PUMMELO?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Ellagic Acid, Curcumin, Phloretin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Kusaina, DNA Kugadzirisa, Adherens junction uye PI3K-AKT-MTOR Signaling nevamwe. Red Raspberry inokurudzirwa Leiomyosarcoma apo inoenderera mberi kurapwa kwegomarara iri Fluorouracil. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeFluorouracil.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Curcumin, Caffeic Acid, Phloretin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Repair uye Oxidative Stress nevamwe. Pummelo haikurudzirwe kuLeiomyosarcoma kana ichiramba ichirapwa kenza iri Fluorouracil nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO RED RASPBERRY INOKURUDZWA PAMUSORO PEPUMMELO YELeiomyosarcoma NEKURAPA Fluorouracil.

Sarudza Nut COMMON WALNUT kana CHESTNUT?

Yakajairika Walnut ine akawanda anoshanda zvinongedzo kana bioactives seQuercetin, Ellagic Acid, Curcumin, Phloretin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, DNA Repair, NFKB Signaling uye Focal Adhesion nevamwe. Common Walnut inokurudzirwa Leiomyosarcoma kana chirwere chegomarara chiri kuramba chiri Fluorouracil. Izvi zvinodaro nekuti Common Walnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mhedzisiro yeFluorouracil.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut Ellagic Acid, Curcumin, Caffeic Acid, Phloretin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress uye Netrin Signaling nevamwe. Chestnut haikurudzirwe kuLeiomyosarcoma kana ichiramba ichirapwa kenza iri Fluorouracil nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

WALNUT YAKAWANDA INOKURUDZWA PAMUSORO PACHESTNUT YELeiomyosarcoma UYE KURAPA Fluorouracil.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeLeiomyosarcoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GARDEN CRESS kana SHALLOT?

Vegetable Garden Cress ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Lupeol, Daidzein, Formononetin, Benzyl Isothiocyanate. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical dzakaita seSero Cycle Checkpoints, Angiogenesis, Growth Factor Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Bindu Cress inokurudzirwa kune njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2. Izvi zvinodaro nekuti Bindu Cress inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuriwo Shallot ndeye Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye Oncogenic Cancer Epigenetics nevamwe. Shallot haina kukurudzirwa kana njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2 nekuti inowedzera siginecha nzira dzayo.

VEGETABLE GARDEN CRESS INOKURUDZWA PAMUSORO PESHALLOT YEMAP2 GENETIC RISK YECANCER.

Sarudza Muchero GRAPEFRUIT/PUMMELO HYBRID kana MBEU YEMUTI WEBREADNUT?

Chibereko Grapefruit/pummelo Hybrid ine zvinhu zvakawanda zvinoshanda kana bioactives seApigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, MYC Signaling, Stem Cell Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Grapefruit/pummelo Hybrid inokurudzirwa kune njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2. Izvi zvinodaro nekuti Grapefruit/pummelo Hybrid inowedzera idzo biochemical nzira dzinopokana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Breadnut Tree Mbeu ndeye Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seSero Cycle Checkpoints, DNA Repair uye Oncogenic Cancer Epigenetics nevamwe. Breadnut Tree Mbeu haikurudzirwe kana njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2 nekuti inowedzera siginecha nzira dzayo.

FRUIT GRAPEFRUIT/PUMMELO HYBRID INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PAMUSORO POMUTI WEMUTI WEMAP2 GENETIC RISK OF CANCER.

Sarudza Nut COMMON HAZELNUT kana EUROPEAN CHESTNUT?

Common Hazelnut ine akawanda anoshanda zvinhu kana bioactives akadai Curcumin, Quercetin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, MYC Signaling, Stem Cell Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Yakajairika Hazelnut inokurudzirwa kune njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Curcumin, Quercetin, Ellagic Acid, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye Oncogenic Cancer Epigenetics nevamwe. European Chestnut haikurudzirwe kana njodzi yeLeiomyosarcoma kana yakabatana genetic njodzi iri MAP2 nekuti inowedzera siginecha nzira dzayo.

COMMON HAZELNUT INOKURUDZWA PAMUSORO PEEUROPA CHESTNUT YEMAP2 GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seLeiomyosarcoma. Varwere veLeiomyosarcoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seLeiomyosarcoma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seGiant Butterbur chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Leiomyosarcoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Sarc Tcga Pan Can Atlas 2018
• Cell-of-Origin Patterns Inotonga Molecular Classification ye10,000 Tumors kubva ku33 Types dzeCancer.
• Scalable Yakavhurika Sainzi Nzira Yekuchinja Kufona kweTumor Exomes Uchishandisa Multiple Genomic Pipelines.
• Genomic uye Inoshanda Nzira dzekunzwisisa Cancer Aneuploidy.
• Driver Fusions uye Zvazvinoreva Mukusimudzira neKurapwa kweMagomarara Evanhu.
• Iyo Yakabatanidzwa TCGA Pan-Cancer Clinical Data Resource kuDhivha Yakakwirira-Unhu Kupona Kwemhedzisiro Yekuongorora.
• Oncogenic Signaling Pathways muCancer Genome Atlas.
• Microbiome ongororo yeropa uye matishu inoratidza nzira yekuongorora cancer.
• Maonero paOncogenic Maitiro pakupera kwekutanga kweCancer Genomics.
• Mamiriro eMicrosatellite Kusagadzikana Pakati pe39 Cancer Types.
• Iyo citrus flavonoid naringenin inokurudzira DNA kugadziriswa mumasero ekenza yeprostate.
• Zvokudya D-glucarate zvinokonzerwa nehutachiona hwekuzvimba panguva yekutanga-yekutanga matanho e benzo [a] pyrene-induced lung tumorigenesis muA/J mice.
• Negative regulation ye signal transducer uye activator ye transcription-3 signing cascade ne lupeol inhibits kukura uye induces apoptosis muhepatocellular carcinoma masero.
• https://my.clevelandclinic.org/health/diseases/22059-leiomyosarcoma
• https://www.ncbi.nlm.nih.gov/books/NBK551667
• https://rarediseases.org/rare-diseases/leiomyosarcoma