Muchidimbu
Zvakawanikwa kubva kuongororo dzakasiyana-siyana zvinoratidza kuti vanhu vanoshandisa fodya isina fodya vari panyatwa huru yekubatwa nemhando dzakasiyana dzegomarara dzinosanganisira dzemusoro negotsi, kunyanya dzemukanwa, pharyngeal, gomarara regurokuro, regurokuro; uye pancreatic cancer. Fodya isina utsi haisi imwe nzira yakachengeteka pane kusvuta fodya. Zvisineyi nerudzi, maumbirwo uye nzira dzekubikisa, zvigadzirwa zvese zvefodya (zvingave zvakatorwa zvega kana nebetel leaf, areca nut/betel nut uye slaked lime) zvinofanirwa kunzi zvinokuvadza uye kushandiswa kwazvo kunofanirwa kurambidzwa zvakanyanya kuderedza njodzi kenza.
Kunwa fodya ndechimwe chezvikonzero zvinokonzera gomarara. Sekureva kwesangano reWorld Health Organisation, kunwa fodya kunouraya vanhu vanodarika mamirioni masere pagore pasirese. Kune vanhu vanosvika 8 bhiriyoni vanoshandisa fodya pasirese uye vanopfuura makumi masere muzana avo vanogara munyika dzakaderera nedzepakati mari. Vanhu vanowanzo shandisa zvigadzirwa zvefodya nicotine, chinhu chinodhakisa chemakemikari chiripo mumuti wefodya.
Kunze kwenikotini, utsi hwefodya zvakare hune makemikari anodarika zviuru mazana manomwe anosanganisira makumi manomwe emakemikari anogona kukonzera kenza, mazhinji acho achikanganisa iyo DNA. Mamwe emakemikari aya anosanganisira hydrogen cyanide, formaldehyde, lead, arsenic, ammonia, benzene, carbon monoxide, nitrosamines uye polycyclic anonhuwirira mahydrocarbon (PAHs). Mashizha efodya anewo zvimwe zvinhu zvine mwaranzi zvakaita seUranium, Polonium-7000 uye Lead-70 ayo anonwiwa kubva kufotereza yephosphate, ivhu nemhepo. Kushandiswa kwefodya kunogona kutungamira kumarudzi mazhinji ekenza, kusanganisira mapapu, laryngeal, muromo, esophageal, huro, dundira, itsvo, chiropa, mudumbu, pancreatic, colon, rectal uye cancer yekenza, pamwe neacute myeloid leukemia.
Izvi zvinotungamira kumubvunzo wekuti kushandiswa kwefodya isina utsi ndiyo nzira yakachengeteka pane kuputa fodya nezvimwe zvigadzirwa zvefodya here? Ngationei!
Chii chinonzi Fodya Isina Utsi?
Fodya isina utsi nefodya zvinogadzirwa nemuromo kana nemumhino, pasina kupisa chigadzirwa. Kune mhando dzakawanda dzezvinhu zvisina hutsi hwefodya zvinosanganisira fodya iri kutsengwa, fodya, snus uye fodya inonyungudika.
Kutsenga, Oral kana Kusvipa fodya
Aya mashizha akasununguka, mapulagi, kana kumonyoroka kwefodya yakaomeswa inogona kunge yakamenywa, iyo inodzeya kana kuiswa pakati pe dama nechaini kana mazino, uye mate ebrown anozobuda anosvipirwa kana kumedzwa. Iyo nicotine irimo mufodya inonwiwa kuburikidza nemumuromo matishu.
Snuff kana Kunyudza fodya
Iyi fodya yakatsetseka, inotengeswa seyakaoma kana mafomu akanyorova, uye inogona kunge iine zvinonhuwira zvakawedzerwa. Fodya yakaoma, inowanika muhupfu, inosvirwa kana kufemerwa nemumhino. Chinyoro nyoro chinoiswa pakati pemuromo wezasi kana dama uye chingamu uye iyo nicotine inosvinwa kuburikidza nematinji emuromo.
snus
Rudzi rwe snuff nyoro yakasanganiswa nezvinonhuwira kana michero, iyo inobatwa pakati pegum nemumuromo matishu uye muto unomedzwa.
Fodya isingadzimiki
Izvi zvine furawa, inonyungudika, yakadzvanywa, fodya ine hupfu iyo inonyungudika mumuromo uye isingade kusvipirwa muto wefodya.
Kunge fodya, midzanga uye zvimwe zvinogadzirwa nefodya, kushandiswa kwefodya isina chiutsi kunopindwa muropa nekuda kwechinhu checikotini.
Pane pane Cancer Inokonzera makemikari mune isina Fodya Fodya Zvigadzirwa?
Vazhinji vedu tine fungidziro isiriyo yekuti zvigadzirwa zvefodya isina hutsi inzira dzakachengeteka pane kuputa fodya nekuti dzinogona kunge dzisina kubatana nemapapu. kenza. Zvisinei, ngozi yokuva nekenza haingoitwi kune vaya “vanosvuta” fodya. Vanhu vanoshandisa fodya isina hutsi vanowanzoitawo marudzi akasiyana egomarara. Kutaura idi, hapana rudzi rwakakotsekana rwefodya kana mwero wakachengeteka wokushandiswa kwefodya.
Kune makumi maviri nemasere akasiyana gomarara rinokonzera vamiririri kana ma carcinogen anoonekwa mune isina fodya zvigadzirwa. Pakati peizvi, zvinhu zvinonyanya kukonzera kenza zvinokanganisa fodya-yakanangana nitrosamines (TSNAs). Pamusoro peTSNAs, mamwe ma carcinogen aripo mufodya isina chiutsi anosanganisira N-nitrosoamino acids, volatile N-nitrosamines, volatile aldehydes, polynuclear aromatic hydrocarbons (PAHs) uye radioactive zvinhu zvakaita se polonium-28 uye uranium-210 uye -235. (International Agency yekutsvaga nezveCancer (IARC), World Health Organisation)
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
Njodzi Dzoutano Dzakabatana nefodya isina chiutsi
Nekuda kwekuvapo kwemakemikari anokuvadza uye carcinogen, kushandiswa kwefodya isina hutsi zvigadzirwa kunoenderanawo nenyaya dzakasiyana dzehutano. Zvimwe zvacho zvakanyorwa pazasi:
- Njodzi dzemhando dzakasiyana dzekenza
- Kuwedzera kuratidzwa nicotine semichero yefodya isina utsi inowanzo shandiswa zvakanyanya kufananidzwa nekusvuta fodya kunoitwa nguva nenguva pazuva.
- Njodzi yezvirwere zvemoyo
- Inokonzeresa kuzvirwere zvematadza, mazino anokundikana, kurasikirwa mazino, kudzikama kwemazino, kusuka mazino, mweya wakaipa, kurasikirwa kwepfupa kwakatenderedza midzi uye kusviba kwemeno.
- Precancerous Oral maronda senge leukoplakia
- Kuonekwa kwakaita semapipi kweimwe fodya isina chiutsi kunogona kukwezva vana uye kunotungamira kune nicotine chepfu.
Fodya Isina Utsi Uye Njodzi Kenza
Zvidzidzo zvakasiyana uye kuongororwa kwakarongeka kwakaitwa nevatsvagiri pasirese kuti vaongorore kusangana pakati pekushandisa fodya isina hutsi nekenza. Zviwanikwa kubva kune zvimwe zvezvidzidzo zvakaunganidzwa pazasi.
Kusvuta Fodya Isingashandise uye Njodzi Yomukanwa Oral
- Vanotsvagurudza kubva kuICMR-National Institute yeCancer Kudzivirira uye Tsvagiridzo, India yakaita ongororo ye37 zvidzidzo zvakaburitswa pakati pa1960 na2016, kuongorora mubatanidzwa pakati pekushandisa fodya isina hutsi nekenza yemukanwa. Izvo zvidzidzo zvakawanikwa kuburikidza nekutsvaga kwemabhuku mune iyo Pubmed, Indmed, EMBASE, uye Google Scholar dhatabhesi / injini dzekutsvaga. Vatsvakurudzi vakaona kuti fodya isina utsi yaibatanidzwa nenjodzi yakanyanya kuwedzera yekenza yemuromo, kunyanya kumatunhu ekumaodzanyemba kwakadziva kumabvazuva kweAsia, kuEastern Mediterranean Regions, uye pakati pevashandisi vevakadzi. (Smita Asthana et al, Nicotine Tob Res., 2019)
- Mune meta-ongororo yezvidzidzo makumi maviri neshanu zvakaitwa nevatsvagiri vekuIndia, vakaona kuti kushandisa fodya isina chiutsi kwakabatana nekuwedzera kukuru mumuromo, pharyngeal, laryngeal, esophageal uye kanzuru dzemudumbu. Vakawana zvakare kuti kana tichienzaniswa nevarume, vakadzi vaive nenjodzi yakanyanya yekenza yemukanwa, asi mukana wakaderera wekenza yesophageal. (Dhirendra N Sinha et al, Int J Cancer., 25)
- Vanotsvagurudza kubva kuLeibniz Institute for Prevention Research uye Epidemiology-BIPS kuGerman neKhyber Medical University muPakistan, vakaita ongororo yakarongeka yezvinyorwa makumi maviri nesere kuongorora njodzi yekenza yemukanwa nekushandisa mhando dzakasiyana dzefodya isina utsi. Iyo data yakawanikwa kuburikidza nekutsvaga kwemabhuku muMedline uye ISI Webhu reRuzivo, kuitira ongororo dzekuongorora dzakaburitswa muSouth Asia kubva muna21 kusvika 1984. Vakaona kuti kutsenga fodya uye kushandiswa kwepani nefodya kwaibatanidzwa nenjodzi yakawedzera yekenza yemukanwa. (Zohaib Khan et al, J Cancer Epidemiol., 2013)
- Meta-ongororo yezvidzidzo gumi neshanu yakaitwa nevatsvagiri veYunivhesiti yeGriffith kuAustralia kuti vaongorore kusangana pakati pekushandisa fodya isina hutsi chero ipi zvayo, chero betel quid (ine betel leaf, areca nut / betel nut uye slaked lime) isina fodya uye areca nati, ine chiitiko chekenza yemuromo muSouth Asia nePacific. Zvidzidzo zvakawanikwa kuburikidza nekutsvaga kwemabhuku muPubmed, CINAHL neCochrane dhatabhesi kusvika munaJune 15. Chidzidzo chacho chakawana kuti kutsenga fodya kunoenderana zvakanyanya nenjodzi yakawedzera ye squamous-cell carcinoma yemuromo wemuromo. Chidzidzo ichi chakawana zvakare kuti kushandiswa kwebetel quid (iine shizha rebetel, areca nut / betel nut uye slaked lime) isina fodya kwakakonzerawo njodzi yakawedzera yekenza yemukanwa, pamwe nekuda kweccinogenicity ye areca nut.
Zvakawanikwa muzviongorori izvi zvinoratidza kubatana kwakasimba pakati pekushandiswa kwemhando dzakasiyana dzefodya isina utsi (iine kana isina shizha rebetel, areca nut / betel nut uye slaked lime) uye kuwedzera njodzi yekenza yemukanwa.
Kusvuta Fodya Isingashandise uye Musoro uye Neck Kanjodzi Njodzi
Vatsvagiri kubva kuNational Institute of Environmental Health Sayenzi, North Carolina vakaongorora data kubva ku11 US kesi-control zvidzidzo (1981-2006) yemuromo, pharyngeal, uye laryngeal cancers inosanganisira 6,772 kesi uye 8,375 kutonga, muInternational Head uye Neck Cancer Epidemiology ( INHANCE) Consortium. Vakaona kuti vanhu vasina kumbobvira vaputa fodya asi vakashandisa fodya vaibatanidzwa zvakanyanya nengozi yegomarara remusoro nemutsipa, kunyanya muromo. kanzira. Pamusoro pezvo, vakawana kuti kutsenga fodya kwakabatana zvakanyanya nenjodzi yakawedzera yegomarara remuromo, kunyangwe kushamwaridzana kwakawanikwa kusina simba apo dzimwe nzvimbo dzese dzegomarara dzemusoro nemutsipa dzakaongororwa pamwe chete. (Annah B Wyss et al, Am J Epidemiol., 2016)
Chidzidzo ichi chakagumisa kuti fodya isina utsi inogona kunge ichibatanidzwa nenjodzi inowedzera yemakenza emusoro nemutsipa, kunyanya kanzura dzemumuromo, nenjodzi yakanyanya kukwidziridzwa kana uchishandisa fodya kana ichienzaniswa neyekutsenga fodya.
Doro uye Fodya Kutsvaga uye Njodzi yeHIVV Infection muMusoro uye Neck Cancer Varwere
Vatsvagiri kubva kuIndia vakaongorora mhedzisiro kubva kumasampuli akatorwa kubva ku106 musoro nemutsipa kenza varwere vakawana kubva kuHead and Neck oncology surgery unit ya Dr. Bhubaneswar Borooah Cancer Institute (BBCI), Regional Cancer Center, Guwahati, India kuti vaongorore hutachiona hweHPV (hr-HPV) uye kushamwaridzana kwayo nemararamiro emararamiro anosanganisira fodya uye doro. . Varwere vakanyoreswa pakati paOctober 2011 naSeptember 2013. (Rupesh Kumar et al, PLoS One., 2015)
Yakanyanya njodzi hutachiona hweHIVV yakawanikwa mu31.13% yemusoro nemutsipa kenza varwere. Chidzidzo ichi chakawana kuti kunwa doro uye kutsenga kwefodya kwaive kwakabatana zvakanyanya nenjodzi yekuwedzera kwehutachiona hweHR-HPV mumakenza emusoro nemutsipa. Vakawedzera zvakare kuti kana ichienzaniswa nehutachiona hweHPV-18, HPV-16 yakawanikwa ichinyanyobatanidzwa nekutsenga kwefodya.
Kusvuta Fodya Isingashandise uye Esophageal Kenza Njodzi
Mune ongororo yakaitwa nevatsvakurudzi veKuwait University, vakaongorora kubatana kuri pakati pekutsenga areca nut, betel quid (iine shizha rebetel, areca nut / betel nut uye slaked lime), fodya yemumuromo, kusvuta fodya uye njodzi yesophageal squamous-cell carcinoma / cancer muSouth Asians. Chidzidzo chacho chakashandisa data kubva pazviitiko makumi mapfumbamwe nemapfumbamwe zveesophageal squamous-cell carcinoma uye makumi matatu nematanhatu akaenzana ekudzora kubva kuzvipatara zvitatu zvepamusoro muKarachi, Pakistan.
Ongororo yavo yakawana kuti vanhu vaitsenga areca nati, vakatsenga betel quid (yaive neshizha rebhetel, areca nut / betel nut uye slaked lime) nefodya, vaidzidzira fodya yekunyudza kana kusvuta midzanga vaibatanidzwa nenjodzi yakawedzera yesophageal squamous-cell carcinoma / cancer. . Njodzi yesophageal squamous-cell carcinoma / cancer yakawedzera kuwedzerwa kune avo vaiputa midzanga pamwe nekutsenga betel quid (ine betel shizha, areca nati / betel nut uye slaked lime) nefodya, kana mune avo vanoputa fodya pamwe ne aidzidzira kunyudza. (Saeed Akhtar et al, Eur J Kenza., 2012)
Kusvuta Fodya Isingashandise uye Pancreatic Kenza Njodzi
Vanotsvagurudza kubva kuICMR-National Institute yeCancer Kudzivirira & Tsvagiridzo, Noida uye Chikoro Chekudzivirira Oncology, Patna, India vakadzidza hukama pakati pefodya isina chiutsi uye nenjodzi yemhando dzakasiyana dzekenza. Vakashandisa dhata kubva kuongororo makumi masere, yaisanganisira fungidziro dzengozi gumi nemaviri dzekenza dzakasiyana, dzakawanikwa kuburikidza nekutsvaga mabhuku muPubMed neGoogle Scholar dhatabhesi maringe nezvidzidzo zvakaburitswa kubva 80 kusvika Ndira 121 pane fodya isina hutsi nekenza. (Sanjay Gupta et al, Indian J Med Res., 1985)
Chidzidzo ichi chakawana kuti kushandiswa kwefodya isina chiutsi kwakabatana neyakawedzera njodzi yemukenza wepamuromo, wesophageal nepancreatic; nenjodzi yemakenza emuromo uye esophageal anonyanya kuwanda muSouth-East Asia Dunhu uye Kumabvazuva kweMediterranean Dunhu, uye gomarara repancreatic mudunhu reEuropean.
mhedziso
Ongororo dzakasiyana dzakaratidza kuti vanhu vanoshandisa fodya isina fodya vari panjodzi huru yekubatwa nemhando dzakasiyana dzegomarara dzinosanganisira musoro nemutsipa, kunyanya wemukanwa. kenza, kenza yehuro, kenza yehuro, kenza yegurokuro; uye pancreatic cancer. Izvi zvinopa humbowo hwekuti zvisinei nerudzi, maumbirwo uye nzira dzekutora, zvese zvigadzirwa zvefodya (zvingave zvakatorwa zvega kana pamwe chete nebetel leaf, areca nut/betel nut uye slaked slime) zvinokuvadza uye zvinogona kukonzera mhando dzakasiyana dzegomarara nedzimwe nyaya dzehutano. Nekudaro, kushandiswa kwezvinhu zvese zvefodya kusanganisira fodya isina hutsi kunofanirwa kurambidzwa zvakanyanya.
Chikafu chipi chaunodya uye chinowedzera iwe kutora chisarudzo chaunoita. Sarudzo yako inofanirwa kusanganisira kutarisisa kwecancer genes shanduko, iyo kenza, kurapwa kuri kuenderera uye zvinowedzerana, chero mairigeji, ruzivo rwemararamiro, huremu, kukwirira uye maitiro.
Kurongeka kwehutano kwekenza kubva kuAddon hakubvi pakutsvaga kweinternet. Iyo inoshandura sarudzo kuitirwa iwe zvichibva pane samorekuru sainzi inoitwa nemasayendisiti edu uye mainjiniya esoftware. Zvisinei kuti une hanya here nekunzwisisa iyo yepasi biochemical molecular pathways kana kwete - yekuronga kudya kwemukenza kunzwisiswa kunodiwa.
Tanga IZVOZVO nekuronga kwako kudya kunovaka muviri nekupindura mibvunzo pazita rekenza, majini masayendisiti, kurapwa kuri kuenderera uye zvinowedzerana, chero kurwara, tsika, mararamiro, boka rezera uye murume kana murume.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
Varwere veCancer kazhinji vanofanirwa kubata zvakasiyana chemotherapy mhedzisiro izvo zvinokanganisa kwavo hupenyu hwehupenyu uye kutarisa kune dzimwe nzira dzokurapa kenza. Kutora iyo kudya kwakakwana uye zvekuwedzera zvinoenderana nesainzi (kunzvenga kufungidzira uye kusarudzika kusarudza) ndiwo mushonga wepanyama wekenza uye mitezo inoenderana nekurapwa.