Muchidimbu
Gomarara rehucheche senge leukemia inorapwa neakakwira kuwanda kwechemotherapy senge cyclophosphamides uye anthracyclines, vanotarisana nenjodzi yekuwedzera kanzira inotevera / yechipiri. Sekondari / Yechipiri Kenza mune vakapona gomarara vakapona zvakajairika kwenguva refu chemotherapy divi mhedzisiro.
Cancers Yevacheche
Zvirwere zvegomarara zvevana zvinowanzoitika muvana, vechidiki uye vechidiki. Gomarara rinonyanyozivikanwa muvana ileukemia, gomarara reropa. Dzimwe mhando dzegomarara senge lymphoma, mamota europi, sarcomas uye mamwe mamota akasimba anogonawo kuitika. Nekuda kwekurapa kwakavandudzwa, kune vanopfuura 80% yevacheche vanopona kenza muUS. Kurapa kunoenderana nerudzi rwegomarara asi kunogona kusanganisira kuvhiyiwa, chemotherapy, kurapwa nemwaranzi uye munguva pfupi yapfuura kunyange immunotherapy. Nekudaro, sekureva kweNational Pediatric Cancer Foundation, vanofungidzira kuti vanopfuura makumi mapfumbamwe neshanu muzana evacheche vanopona negomarara vachange vaine nyaya ine chekuita nehutano panguva yavanenge vava nemakore makumi mana nemashanu, izvo zvinogona kunge zviri mhedzisiro yekurapwa kwavo kenza kwekutanga.https://nationalpcf.org/facts-about-childhood-cancer/).
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
Kenza Yechipiri muVacheche Kenza Kenza
Nekuvapo kwenhamba huru yevakapona gomarara, vaongorori kubva kuYunivhesiti yeMinnesota Medical School vakaongorora kusangana kwevanopona nekenza yevana vakabatwa nekemotherapy nezviitiko zveinotevera malignant neoplasm (SMN) sechikamu chevacheche vakapona gomarara kudzidza (Turcotte LM et al, J Clin Oncol., 2019). Vakaongorora maSMN muvakapona vakatanga kubatwa kenza pavakange vari pasi pemakore makumi maviri nerimwe, pakati pa21-1970. Izvo zvakakosha zvehuwandu hwehuwandu hwevanhu uye zviwanikwa zvekuongorora kwavo ndezvi:
- Makore ekuMedhia pakuonekwa aive makore manomwe uye epakati zera pakupedzisira kwekutevera yaive makore 7.
- Vakaongorora vakapfuura makumi maviri evapukunyuki vevacheche vaibatwa nechemotherapy chete, chemotherapy pamwe neye radiation radiation, radiation radiation chete kana kwete.
- Vakapona pahudiki vaibatwa nekemotherapy chete vaive ne2.8 pangozi yakawedzera njodzi yeSMN.
- Chiyero chezviitiko zveSMN yaive yakakwira muvapenyu vevacheche vaibatwa neplatinotherapy. Pamusoro pezvo, yea alkylating agents (Eg. Cyclophosphamide) uye anthracyclines (Eg. Doxorubicin), kwaive nehukama hwekupindura dhizaini hwakaonekwa pakati pemiyero yepamusoro yeiyi chemotherapy uye yakakwira chiitiko chegomarara repazamu.
Njodzi yeChipiri Chekutanga Chipfuva Chebonde muLeukemia kana Sarcoma Vanopona
Mune kumwe kuongorora kwekutanga sechikamu chekenza yevanopona nekenza pahucheche iyo yaisanganisira 3,768 vechikadzi chirwere cheleukemia kana kenza yesarcoma vakapukunyuka vakabatwa nekuwedzera kweiyo chemotherapy senge cyclophosphamide kana anthracyclines, zvakaonekwa kuti zvaive zvine chekuita nenjodzi yekuva nekenza yepazamu yepiri / yechipiri. Paive ne5.3 fold uye 4.1 yakapetwa yakawedzera njodzi yekuvandudza wechipiri / wechipiri kenza yemazamu mune sarcoma uye vakapona veleukemia zvichiteerana. (Henderson TO et al., J Clin Oncol., 2016)
Njodzi yeSecondary Ganda Ganda mune Yevacheche Cancer Vanopona avo vakambowana Radiotherapy
Zvinoenderana nezvakawanikwa kubva kune imwe ongororo inonzi DCOG-LATER cohort study iyo yaisanganisira 5843 maDutch vakapona negomarara revana vakawanikwa vaine mhando dzakasiyana dzechirwere ichi. kanzira pakati pa1963 na2001, vakapona vakamborapwa neradiotherapy vaive nenjodzi yakawedzera yegomarara reganda rechipiri Chidzidzo ichi chakawana kakapetwa makumi matatu njodzi yebasal cell carcinomas mune vakapona ava. Izvi zvinoenderanawo nehuwandu hwenzvimbo yeganda yakaratidzwa panguva yekurapa. (Jop C Teepen et al, J Natl Cancer Inst., 2019)
mhedziso
Muchidimbu, vakapona negomarara rehucheche vakarapwa neakakwira madosi ekemotherapy senge cyclophosphamide kana anthracyclines ekenza senge leukemia vanotarisana nenjodzi yekuwedzera inotevera yechipiri / yechipiri kenza (yakareba chemotherapy side effect). Nokudaro, kuongororwa kwengozi-kubatsirwa kwe kenza kurapwa kwevana nevakuru vechidiki kunofanira kufarira kurapwa nekudzikisira kuwanda kwedosi yechemotherapy uye kufunga nezveimwe nzira kana yakawanda yakanangwa nzira dzekurapa kuderedza njodzi yekuva neanozotevera magomarara mune ramangwana.
Chikafu chipi chaunodya uye chinowedzera iwe kutora chisarudzo chaunoita. Sarudzo yako inofanirwa kusanganisira kutarisisa kwecancer genes shanduko, iyo kenza, kurapwa kuri kuenderera uye zvinowedzerana, chero mairigeji, ruzivo rwemararamiro, huremu, kukwirira uye maitiro.
Kurongeka kwehutano kwekenza kubva kuAddon hakubvi pakutsvaga kweinternet. Iyo inoshandura sarudzo kuitirwa iwe zvichibva pane samorekuru sainzi inoitwa nemasayendisiti edu uye mainjiniya esoftware. Zvisinei kuti une hanya here nekunzwisisa iyo yepasi biochemical molecular pathways kana kwete - yekuronga kudya kwemukenza kunzwisiswa kunodiwa.
Tanga IZVOZVO nekuronga kwako kudya kunovaka muviri nekupindura mibvunzo pazita rekenza, majini masayendisiti, kurapwa kuri kuenderera uye zvinowedzerana, chero kurwara, tsika, mararamiro, boka rezera uye murume kana murume.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
Varwere veCancer kazhinji vanofanirwa kubata zvakasiyana chemotherapy mhedzisiro izvo zvinokanganisa kwavo hupenyu hwehupenyu uye kutarisa kune dzimwe nzira dzokurapa kenza. Kutora iyo kudya kwakakwana uye zvekuwedzera zvinoenderana nesainzi (Kudzivirira kufungidzira uye kusarudzika kusarudza) ndiyo yakanyanya kurongeka mushonga wekenza uye kurapwa kwakanangana nemhedzisiro.