Ndi khansa iti yomwe ingapindule pophatikiza Thyme muzakudya zawo?

Mfundo

Thyme amadziwika kwambiri chifukwa cha thanzi lake ndipo amagwiritsidwa ntchito kawirikawiri ndi odwala khansa komanso omwe ali pachiopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Thyme kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, mankhwala ena, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Thyme ikhoza kupindulitsa omwe ali ndi Primary Extraskeletal Myxoid Chondrosarcoma omwe akudwala Dexamethasone, koma sizingakhale zabwino kwa odwala omwe akulandira Radiation for Primary Urethral Squamous Cell Carcinoma. Kuphatikiza apo, ngakhale Thyme ikhoza kuthandiza anthu omwe ali ndi chiwopsezo cha chibadwa "ASXL1", sizingaganizidwe kwa omwe ali ndi chiwopsezo chosiyana "CTNNB1". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Thyme kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Thyme ndi chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zotsatira zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Thyme m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunika kwambiri likubuka: Kodi muyenera kuphatikiza Thyme muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndizoyenera kudya Thyme ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya ASXL1? Bwanji ngati m'malo mwake chiwopsezo chanu cha majini chimachokera ku jini ya CTNNB1? Kodi ndizopindulitsa kuphatikiza Thyme muzakudya zanu ngati mwapezeka ndi Primary Urethral Squamous Cell Carcinoma, kapena ngati matenda anu ali Primary Extraskeletal Myxoid Chondrosarcoma? Komanso, kodi mungasinthire bwanji kumwa kwanu kwa Thyme ngati mukulandira chithandizo cha Dexamethasone kapena ngati dongosolo lanu lamankhwala likusintha kuchoka ku Dexamethasone kupita ku Radiation? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Thyme ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Thyme imalimbitsa chitetezo cha mthupi' ndizosakwanira pa zosankha za chakudya / zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kwa kuphatikiza Thyme muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Thyme muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zachilengedwe chonse chazinthu zonse, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, ma genetic predispositions. , ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Mukapezeka ndi mtundu wina wa khansa, monga Primary Extraskeletal Myxoid Chondrosarcoma kapena Primary Urethral Squamous Cell Carcinoma, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda. ”

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndiloti mungakhale ndi chiopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Thyme. Kodi chiwopsezo cha chibadwa cha khansa chomwe chimachokera ku kusintha kwa ASXL1 chimakhala ndi njira yofananira ndi kusintha kwa CTNNB1? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Extraskeletal Myxoid Chondrosarcoma chikufanana ndi Primary Urethral Squamous Cell Carcinoma? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akudwala Radiation monga omwe amalandira Dexamethasone? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Thyme - Chakudya Chakudya Chowonjezera

Thyme yowonjezera imaphatikizapo zinthu zambiri zomwe zimagwira ntchito, kuphatikizapo Vitamini K, Vitamini C, Ursolic Acid, Thymol ndi Salicylic Acid, iliyonse yomwe ilipo mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka MYC Signaling, RAS-RAF Signaling, Epithelial to Mesenchymal Transition ndi Cell Cycle Checkpoints, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Thyme, zokha kapena zophatikizana, zimakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito Thyme kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Thyme si chisankho chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Zowonjezera za Thyme

Kuyankha funso loti 'Kodi ndipewe liti Thyme munkhani ya Khansa' ndizovuta chifukwa yankho limakhala la munthu payekhapayekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Thyme zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, ma genetic predispositions, chithandizo chamakono, zowonjezera zina zomwe zimatengedwa, zizolowezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Thyme ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunika koganizira munthu payekha. zisankho zotere.

1. Kodi Mankhwala a Thyme angathandize Odwala a Primary Urethral Squamous Cell Carcinoma omwe akulandira chithandizo cha radiation?

Primary Urethral Squamous Cell Carcinoma imadziwika ndi kusintha kwa majini, komwe ndi BLM, BRCA1 ndi CTCF, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka RAS-RAF Signaling, Androgen Signaling ndi DNA Repair. Kuchita bwino kwa chithandizo cha khansa, monga Radiation, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Thyme, chomwe chimakhudza Chizindikiro cha RAS-RAF, sichingakhale chisankho choyenera pankhani ya Primary Urethral Squamous Cell Carcinoma pamene akudwala Radiation. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Mankhwala a Thyme angathandize Odwala a Myxoid Chondrosarcoma omwe akulandira chithandizo cha Dexamethasone?

Primary Extraskeletal Myxoid Chondrosarcoma imadziwika ndi kusintha kwa majini, monga ARID1A, PIK3C3 ndi TERT, zomwe zimabweretsa kusintha kwa biochemical pathways, makamaka MYC Signaling, Androgen Signaling, Chromatin Remodeling, Autophagy, Inositol Phosphate Signaling, Cell Cyptosis Checkpoints. Kuchita bwino kwa chithandizo cha khansa, monga Dexamethasone, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, chowonjezera cha Thyme ndi njira yabwino kwa iwo omwe ali ndi Primary Extraskeletal Myxoid Chondrosarcoma akukumana ndi Dexamethasone. Izi ndichifukwa choti Thyme imakhudza njira monga MYC Signaling, yomwe imatha kuletsa zinthu zomwe zimayendetsa Primary Extraskeletal Myxoid Chondrosarcoma kapena kupindulitsa mphamvu ya Dexamethasone.

3. Kodi Zowonjezera za Thyme Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi CTNNB1 Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la CTNNB1 nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya CTNNB1 kumakhudza njira za biochemical kapena njira, monga Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa CTNNB1 komwe kumakhudzana ndi chiopsezo chowonjezereka cha Adrenocortical Carcinoma, zomveka za sayansi zimasonyeza kupeŵa kugwiritsa ntchito Thyme yowonjezera. Izi ndichifukwa choti kuwonjezera pa Thyme kumakhudza njira monga Epithelial kupita ku Mesenchymal Transition, zomwe zitha kubweretsa zotsatira zoyipa pakusintha kwa CTNNB1 ndi zovuta zina za khansa.

4. Kodi Zowonjezera za Thyme Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi ASXL1 Mutation Associated Genetic Risk?

ASXL1 imatenga gawo lofunikira pakuwunika chiopsezo cha khansa. Kusintha kwa ASXL1 kumatha kusokoneza njira zovuta zama biochemical, kuphatikiza ma Cell Cycle Checkpoints, Oncogenic Cancer Epigenetics ndi Suppressive Histone Methylation, zomwe zimakhudza kukula kwa khansa. Ngati chibadwa chanu chikuwonetsa masinthidwe a ASXL1 okhudzana ndi Chronic Myelomonocytic Leukemia, ganizirani kuphatikiza zowonjezera za Thyme mu dongosolo lanu lazakudya. Zowonjezera izi zitha kulimbikitsa njira ngati Cell Cycle Checkpoints, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi masinthidwe a ASXL1 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya, kuphatikizapo zakudya ndi zowonjezera monga Thyme chifukwa cha ubwino wake, ndi chida chothandiza chomwe chingathe kulamulidwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• Vitamini C amapha ma cell a khansa ya KRAS ndi BRAF mutant colorectal cancer polunjika ku GAPDH.
• Kukulitsa ndi kufotokoza mopambanitsa kwa c-myc proto-oncogene correlate ndi kutayika kwa kudalira kwa glucocorticoid m'maselo a makoswe osinthidwa ndi mtundu wa papillomavirus wamunthu 16.
• cBioPortal ya Cancer Genomics
• Mucocutaneous lymph node syndrome (Kawasaki syndrome): lipoti la milandu.
• Aspirin ndi salicylic acid amachepetsa mawonekedwe a c-Myc m'maselo a khansa: gawo lomwe lingakhalepo mu chemoprevention.
• Mphamvu ya oncogenic K-RAS pa YB-1 phosphorylation yoyambitsidwa ndi ma radiation ya ionizing.
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• Salicylic acid metabolites ndi zotumphukira zimalepheretsa ntchito ya CDK: Kuwunikira kwaposachedwa pazamankhwala a aspirin polimbana ndi khansa ya colorectal.