Ndi khansa iti yomwe ingapindule pophatikiza Milk Thistle muzakudya zawo?

Mfundo

Thistle yamkaka imadziwika kwambiri chifukwa cha thanzi lake ndipo imagwiritsidwa ntchito pafupipafupi ndi odwala khansa komanso omwe ali pachiwopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Milk Thistle kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Thistle ya Mkaka ikhoza kupindulitsa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma omwe akudwala Mitomycin, koma sizingakhale zabwino kwa odwala omwe akulandira Radiation for Primary Fibromatosis. Kuphatikiza apo, ngakhale nthula ya Mkaka imatha kuthandiza anthu omwe ali ndi chiwopsezo chamtundu wa "TERT", sizingaganizidwe kwa omwe ali ndi chiwopsezo chamtundu wina "CTNNB1". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Milk Thistle kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Milk Thistle ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zonse zomwe zimagwira ntchito muzakudya/zowonjezera monga nthula ya Mkaka m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunikira limabuka: Kodi muyenera kuphatikiza Milk Thistle muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndikofunikira kumwa Mkaka Thistle ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya TERT? Bwanji ngati m'malo mwake chiwopsezo chanu cha majini chimachokera ku jini ya CTNNB1? Kodi ndizopindulitsa kuphatikiza nthula yamkaka m'zakudya zanu ngati mwapezeka ndi Primary Fibromatosis, kapena ngati matenda anu ndi Primary Penile Squamous Cell Carcinoma? Komanso, kodi kumwa kwanu kwa Mkaka wa Thistle kungasinthidwe bwanji ngati mukulandira chithandizo cha Mitomycin kapena ngati dongosolo lanu lamankhwala likuchoka ku Mitomycin kupita ku Radiation? Ndikofunikira kuzindikira kuti zonena zosavuta monga 'Thula la Mkaka ndi lachilengedwe, kotero zimakhala zopindulitsa nthawi zonse' kapena 'Mkaka wa Mkaka umalimbitsa chitetezo chathupi' ndizosakwanira kusankha zakudya/zowonjezera zowonjezera.

Kuphatikiza apo, ndikofunikira kuwonanso kuyenera kophatikizira Mkaka Thistle muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Milk Thistle muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira momwe biochemical imakhudzira zosakaniza zonse, poganizira zinthu monga mtundu wa khansa, chithandizo chamankhwala chomwe mukukumana nacho, majini. mayendedwe, ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Akapezeka ndi mtundu wina wa khansa, monga Primary Penile Squamous Cell Carcinoma kapena Primary Fibromatosis, njira zochiritsira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda.

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndilakuti mungakhale ndi chiopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Milk Thistle. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa TERT chimakhala ndi zotsatira zofanana ndi zakusintha kwa CTNNB1? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Penile Squamous Cell Carcinoma chikufanana ndi Primary Fibromatosis? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akudwala Radiation monga omwe amalandira Mitomycin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Mkaka nthula - Chakudya Chakudya Chowonjezera

The Milk Thistle imaphatikizapo zinthu zingapo zogwira ntchito, kuphatikiza Silibinin, Vitamini E, Palmitic Acid, Oleic Acid ndi Linoleic Acid, iliyonse ilipo mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka Kukonzanso kwa DNA, Epithelial to Mesenchymal Transition ndi MYC Signaling, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Milk Thistle, zokha kapena zophatikiza, zimakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito Milk Thistle kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Mkaka Thistle si chisankho chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Zakudya Zamkaka za Mkaka

Kuyankha funso loti 'Kodi Ndipewe Liti Pankhani ya Mkaka Pankhani ya Khansa' ndizovuta chifukwa yankho limakhala la munthu payekhapayekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Milk Thistle zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, chibadwa, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizoloŵezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Mkaka wamkaka ndi woyenera kapena uyenera kupeŵedwa, kutsindika kufunika koganizira zaumwini. muzosankha zotero.

1. Kodi Zakudya Zamkaka Zamkaka Zingathandize Odwala a Primary Fibromatosis omwe akulandira chithandizo cha radiation?

Primary Fibromatosis imadziwika ndi kusintha kwa majini, komwe ndi CTNNB1, KDR ndi CIC, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka Epithelial to Mesenchymal Transition, Adherens junction, Androgen Signaling, Angiogenesis ndi RAS-RAF Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Radiation, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Milk Thistle, chomwe chimakhudza Epithelial to Mesenchymal Transition, sichingakhale chisankho choyenera pankhani ya Primary Fibromatosis mukakumana ndi Radiation. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Zakudya Zamkaka Zamkaka Zingathandize Odwala Omwe Akulandira Chithandizo cha Mitomycin?

Primary Penile Squamous Cell Carcinoma imadziwika ndi kusintha kwa majini, monga ABRAXAS1, PIK3CB ndi NUP93, zomwe zimabweretsa kusintha kwa biochemical pathways, makamaka DNA Repair, Hematopoiesis ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Mitomycin, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, Milk Thistle supplement ndi njira yabwino kwa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma akukumana ndi Mitomycin. Izi zili choncho chifukwa Mkaka wamkaka umakhudza njira monga DNA Repair, zomwe zingathe kulepheretsa zinthu zomwe zimayendetsa Primary Penile Squamous Cell Carcinoma kapena kupindula ndi mphamvu ya Mitomycin.

3. Kodi Zakudya Zamkaka Zamkaka Ndi Zotetezeka Kwa Anthu Athanzi Amene Ali ndi CTNNB1 Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la CTNNB1 nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya CTNNB1 kumakhudza njira za biochemical kapena njira, monga Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa CTNNB1 komwe kumayenderana ndi chiwopsezo chowonjezereka cha Adrenocortical Carcinoma, malingaliro asayansi akuwonetsa kupeŵa kugwiritsa ntchito chowonjezera cha Milk Thistle. Izi ndichifukwa choti kuwonjezera pa Milk Thistle kumakhudza njira ngati Epithelial kupita ku Mesenchymal Transition, zomwe zitha kubweretsa zotsatira zoyipa pakusintha kwa CTNNB1 ndi zovuta zina za khansa.

4. Kodi Zakudya Zamkaka Zamkaka Ndi Zotetezeka Kwa Anthu Athanzi Amene Ali ndi TERT Mutation Associated Genetic Risk?

TERT imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa TERT kumatha kusokoneza njira zovuta zamankhwala, kuphatikiza MYC Signaling ndi DNA Repair, zomwe zimakhudza kukula kwa khansa. Ngati gulu lanu la majini likuwonetsa masinthidwe mu TERT okhudzana ndi Khansa ya Hematological, lingalirani zophatikizira zopatsa mphamvu za Milk Thistle mu dongosolo lanu lazakudya. Zowonjezera izi zitha kulimbikitsa njira ngati MYC Signaling, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi masinthidwe a TERT ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza zakudya ndi zowonjezera monga Mikungudza ya Mkaka, ndi chida chothandiza chomwe mutha kuwongolera mukakumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• Kutsegula kwa PPAR gamma ndi delta ndi conjugated linoleic acid imayimira chitetezo ku matenda oyesera a m'mimba.
• Kuletsa kwa tocotrienol pa eukaryotic DNA polymerase lambda ndi angiogenesis.
• cBioPortal ya Cancer Genomics
• Kukana kwawayilesi m'maselo a khansa ya m'mawere kumalumikizidwa kudzera mu chizindikiro cha TGF-β, hybrid epithelial-mesenchymal phenotype ndi ma cell stem cell.
• Zotsatira za kuchepa kwa kukonza kwa DNA pa cytotoxicity ya mankhwala omwe amagwiritsidwa ntchito pochiza khansa - kuwunika.
• Chithandizo cha khansa chimapanga mawonekedwe olimba a clonal hematopoiesis.
• cBioPortal ya Cancer Genomics
• Udindo wa phospholipase D mu kusamuka ndi kuwukiridwa komwe kumayambitsidwa ndi linoleic acid m'maselo a khansa ya m'mawere.