Ndi khansa iti yomwe ingapindule ndi kuphatikiza Allspice muzakudya zawo?

Mfundo

Allspice amadziwika kwambiri chifukwa cha thanzi lake ndipo amagwiritsidwa ntchito kawirikawiri ndi odwala khansa komanso omwe ali pachiopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Allspice kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Allspice ikhoza kupindulitsa iwo omwe ali ndi Chotupa Chokhazikika Chokhachokha chomwe chili ndi Avastin, koma sizingakhale zabwino kwa odwala omwe amalandira Gemcitabine ya Primary Sarcomaid Carcinoma ya Urinary Bladder. Kuphatikiza apo, ngakhale Allspice ingathandize anthu omwe ali ndi chiwopsezo cha "CDH1", sizingaganizidwe kwa omwe ali ndi chiwopsezo chosiyana "ALK". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Allspice kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Allspice ndi chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Chifukwa chakuti zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zosankha zazakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Allspice m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunikira limabuka: Kodi muyenera kuphatikiza Allspice muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndizoyenera kudya Allspice ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya CDH1? Bwanji ngati m'malo mwake chiopsezo chanu cha majini chimachokera ku jini ya ALK? Kodi ndizopindulitsa kuphatikiza Allspice muzakudya zanu ngati mwapezeka ndi Primary Sarcomatoid Carcinoma of the Urinary Bladder, kapena ngati matenda anu ndi Primary Solitary Fibrous Tumor? Komanso, kodi kumwa kwanu kwa Allspice kungasinthidwe bwanji ngati mukulandira chithandizo cha Avastin kapena ngati dongosolo lanu lamankhwala likuchoka ku Avastin kupita ku Gemcitabine? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Allspice ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Allspice imalimbitsa chitetezo cha mthupi' ndizosakwanira kusankha zakudya / zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kwa kuphatikiza Allspice muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Allspice muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zazachilengedwe zonse zomwe zimapangidwira, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, ma genetic predispositions. , ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Mukapezeka ndi mtundu wina wa khansa, monga Primary Solitary Fibrous Tumor kapena Primary Sarcomatoid Carcinoma ya Urinary Bladder, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi zaka. jenda.”

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndiloti mungakhale ndi chiopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Allspice. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa CDH1 chimakhala ndi njira yofananira ndi kusintha kwa ALK? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Solitary Fibrous Tumor chikufanana ndi Primary Sarcomatoid Carcinoma ya Urinary Bladder? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akukumana ndi Gemcitabine monga omwe amalandira Avastin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Allspice - Chakudya Chakudya Chowonjezera

Chowonjezera cha Allspice chimaphatikizapo zinthu zambiri zogwira ntchito, kuphatikizapo Vitamini C, Folic Acid, Tetradecanoic Acid, 1,8-cineole ndi Beta-caryophyllene, iliyonse yomwe ilipo pazigawo zosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka MYC Signaling, PI3K-AKT-MTOR Signaling, Angiogenesis ndi Chromatin Remodeling, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Allspice, zokha kapena zophatikizana, zimakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito Allspice kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Allspice sichigamulo chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Allspice Zowonjezera

Kuyankha funso loti 'Ndiyenera kupewa liti Allspice munkhani ya Cancer' ndizovuta chifukwa yankho limakhala lamunthu payekhapayekha - limangoti 'Zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Allspice zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, ma genetic predispositions, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizolowezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Allspice ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunikira koganizira munthu payekha. zisankho zotere.

1. Kodi Allspice Supplements ingapindule ndi Primary Sarcomatoid Carcinoma of the Urinary Bladder Odwala omwe akulandira chithandizo cha Gemcitabine?

Primary Sarcomatoid Carcinoma ya Mkodzo Mkodzo imadziwika ndi kusintha kwa majini, komwe ndi ERCC2, KRAS ndi LATS2, zomwe zimatsogolera ku kusintha kwa biochemical pathways, makamaka PI3K-AKT-MTOR Signaling, DNA Repair, Chromatin Remodeling, G-protein-coupled Receptor Signaling. , Chizindikiro cha Growth Factor Signaling ndi Hippo Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Gemcitabine, kumadalira momwe amachitira panjira izi. Njira yabwino imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zoyendetsera khansara, potero kuwonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Muzochitika zotere, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusamvana kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Allspice, chomwe chimakhudza PI3K-AKT-MTOR Signaling, sichingakhale chisankho choyenera pankhani ya Primary Sarcomatoid Carcinoma ya Urinary Bladder pamene ikudutsa Gemcitabine. Izi ndichifukwa choti zitha kukulitsa kukula kwa matendawa kapena kusokoneza chithandizo chamankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi kusintha kulikonse komwe kumadziwika.

2. Kodi Allspice Supplements ingapindule Odwala Omwe Amakhala Okhazikika Omwe Amakhala Omwe Akulandira Chithandizo cha Avastin?

Chotupa Chokhazikika Chokhazikika Chokhazikika chimadziwika ndi kusintha kwa majini, monga BRD4, FLI1 ndi KMT2C, zomwe zimabweretsa kusintha kwa njira za biochemical, makamaka MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation ndi Amino Acid Metabolism. Kuchita bwino kwa chithandizo cha khansa, monga Avastin, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, chowonjezera cha Allspice ndi njira yabwino kwa iwo omwe ali ndi Primary Solitary Fibrous Tumor omwe akukumana ndi Avastin. Izi ndichifukwa choti Allspice imakhudza njira monga MYC Signaling, yomwe imatha kuletsa zinthu zomwe zimayendetsa Primary Solitary Fibrous Tumor kapena kupindulitsa mphamvu ya Avastin.

3. Kodi Allspice Supplements Ndi Yotetezeka kwa Anthu Athanzi Amene Ali ndi ALK Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la ALK nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya ALK kumakhudza njira za biochemical kapena njira, monga Angiogenesis ndi Growth Factor Signaling, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa ALK komwe kumakhudzana ndi chiopsezo chowonjezereka cha Central Nervous System, zomveka za sayansi zimasonyeza kupeŵa kugwiritsa ntchito Allspice yowonjezera. Izi ndichifukwa choti kuwonjezera pa Allspice kumakhudza njira ngati Angiogenesis, zomwe zitha kubweretsa zotsatirapo zoyipa pakusintha kwa ALK ndi zina zokhudzana ndi khansa.

4. Kodi Allspice Supplements Ndi Yotetezeka kwa Anthu Athanzi Amene Ali ndi CDH1 Mutation Associated Genetic Risk?

CDH1 imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa CDH1 kumatha kusokoneza njira zovuta zamankhwala zamankhwala, kuphatikiza Chromatin Remodeling, Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudza kukula kwa khansa. Ngati gulu lanu la majini likuwonetsa masinthidwe a CDH1 okhudzana ndi Gastric Cancer, lingalirani zophatikiza zowonjezera za Allspice mu dongosolo lanu lazakudya. Zowonjezera izi zimatha kukhudza njira monga Chromatin Remodeling, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi kusintha kwa CDH1 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza zakudya ndi zowonjezera monga Allspice, ndi chida chothandiza chomwe chitha kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• β-Caryophyllene imalepheretsa kukula kwa chotupa cholimba komanso metastasis ya lymph node ya B16F10 maselo a melanoma mu mbewa za C57BL / 6N zonenepa kwambiri.
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• cBioPortal ya Cancer Genomics
• cBioPortal ya Cancer Genomics
• JAK1/STAT3 zowongolera zotsatira za β-caryophyllene pa MG-63 osteosarcoma maselo kudzera pa ROS-induced apoptotic mitochondrial pathway ndi DNA kugawanika.
• Sequential protooncogene expression in regenerating impsyo kutsatira kuvulala kwaimpso.
• Udindo wa NF-kappaB ndi Akt/PI3K pakukana kwa ma cell a pancreatic carcinoma motsutsana ndi kufa kwa ma cell a gemcitabine.
• Udindo wa chotupa microenvironment kukana anti-angiogenic mankhwala.