Mfundo
Blog iyi ndi mndandanda wamaphunziro azachipatala ndi zotsatira zowonetsa kuyanjana kwa mavitamini / ma multivitamini komanso chiopsezo cha khansa komanso chidziwitso chambiri pazakudya zachilengedwe za mavitamini osiyanasiyana. Mfundo yaikulu yochokera ku maphunziro osiyanasiyana ndi yakuti kutenga mavitamini kuchokera ku zakudya zachilengedwe kumakhala kopindulitsa kwa ife ndipo kungaphatikizidwe monga gawo la zakudya / zakudya zathu za tsiku ndi tsiku, pamene kugwiritsa ntchito mankhwala owonjezera a multivitamin sikuthandiza ndipo sikuwonjezera phindu lalikulu popereka anti- ubwino wa thanzi la khansa. Kugwiritsiridwa ntchito mopitirira muyeso kwa multivitamin kungagwirizane ndi kuwonjezeka khansa zowopsa ndipo zitha kubweretsa zoopsa. Chifukwa chake ma multivitamin owonjezerawa ayenera kugwiritsidwa ntchito posamalira khansa kapena kupewa pokhapokha atalangizidwa ndi akatswiri azachipatala - pazoyenera komanso momwe alili.
Mavitamini ndi zakudya zofunikira kuchokera kuzakudya ndi zinthu zina zachilengedwe zomwe thupi lathu limafunikira. Kusowa kwa mavitamini apadera kumatha kuyambitsa zovuta zazikulu zomwe zimawoneka ngati zovuta zosiyanasiyana. Kudya moyenera, wathanzi komanso kudya mokwanira mavitamini ndi mavitamini kumalumikizidwa ndi kuchepa kwa ngozi yakufa kuchokera ku matenda amtima ndi khansa. Gwero la michere liyenera kuchokera kuzakudya zomwe timadya, koma munthawi zofulumira zomwe tikukhala, mankhwala a multivitamin tsiku lililonse amalowa m'malo mwa chakudya chopatsa thanzi.
Chowonjezera cha multivitamin patsiku chakhala chizolowezi kwa anthu ambiri padziko lonse lapansi ngati njira yachilengedwe yolimbikitsira thanzi lawo komanso kupewa matenda monga khansa. Kugwiritsa ntchito kwa ma multivitamini kumakulirakulira m'badwo wokalamba wokhalitsa ndi thanzi labwino ndikuthandizira kukhala ndi thanzi labwino. Anthu ambiri amakhulupirira kuti kumwa mavitamini ochuluka kwambiri ndikulimbana ndi ukalamba, kulimbitsa chitetezo komanso kupewa mankhwala, omwe ngakhale sangathandize, sangapweteke. Pali chikhulupiliro chakuti popeza mavitamini amachokera kuzinthu zachilengedwe ndipo amalimbikitsa thanzi labwino, zochulukirapo za izi zotengedwa ngati zowonjezera zimangotipindulitsa. Chifukwa chogwiritsa ntchito mavitamini ndi mavitamini ambiri pamagulu apadziko lonse lapansi, pakhala pakuwunikiridwa kafukufuku wazachipatala wowerengeka omwe adayang'ana mayanjano a mavitamini osiyanasiyana ndi gawo lawo loteteza khansa.
Zowonjezera Zakudya vs. Zowonjezera Zakudya
Kafukufuku waposachedwa wa Friedman School ndi Tufts University School of Medicine adasanthula zabwino zomwe zingachitike chifukwa chogwiritsa ntchito mavitamini. Ofufuzawo adasanthula deta kuchokera kwa achikulire athanzi 27,000 omwe anali azaka 20 kapena kupitilira apo. Kafukufukuyu adawunika kudya kwa michere ya vitamini mwina ngati zakudya zachilengedwe kapena zowonjezera komanso kuyanjana ndi zomwe zimayambitsa kufa, kufa ndi matenda amtima kapena khansa. (Chen F et al, Zolemba za Int. Med, 2019)
Kafukufukuyu adapeza phindu lalikulu la mavitamini opezeka m'zakudya zachilengedwe m'malo moonjezera. Kudya Vitamini K ndi Magnesium yokwanira kuchokera muzakudya kumalumikizidwa ndi chiopsezo chochepa chofa. Kudya kashiamu wochuluka kuchokera kuzowonjezera, zopitilira 1000 mg / tsiku, kumalumikizidwa ndi chiopsezo chachikulu chakufa ndi khansa. Kugwiritsa ntchito mavitamini D opatsirana mwa anthu omwe analibe zizindikilo zakusowa kwa Vitamini D kumalumikizidwa ndi chiopsezo chowonjezeka chakufa ndi khansa.
Pali maphunziro ena azachipatala omwe awunika momwe amagwiritsidwira ntchito mavitamini kapena ma multivitamin supplements ndi chiopsezo cha khansa. Tifupikitsa izi ndi mavitamini kapena ma multivitamini ena kuphatikiza zakudya zawo zachilengedwe, komanso umboni wasayansi komanso wamankhwala pazabwino zawo komanso kuwopsa kwawo ndi khansa.
Vitamini A - Magwero, Ubwino ndi Kuopsa kwa Khansa
Zotsatira: Vitamini A, vitamini wosungunuka ndi mafuta, ndichinthu chofunikira kwambiri chomwe chimathandizira kuwona bwino, khungu labwino, kukula ndikukula kwamaselo, chitetezo chamthupi, kubereka komanso kukula kwa mwana. Pokhala chopatsa thanzi, Vitamini A satulutsidwa ndi thupi la munthu ndipo amachokera ku chakudya chathu chopatsa thanzi. Amapezeka kwambiri munyama monga mkaka, mazira, chiwindi ndi mafuta a chiwindi cha nsomba mumtundu wa retinol, mtundu wa Vitamini A. Umapezekanso m'malo azomera monga karoti, mbatata, sipinachi, papaya, mango ndi dzungu mu mawonekedwe a carotenoids, omwe ndi provitamin A omwe amasinthidwa kukhala retinol ndi thupi la munthu nthawi yakudya. Ngakhale kudya kwa Vitamini A kumapindulitsa thanzi lathu m'njira zambiri, kafukufuku wambiri wazachipatala awunika mgwirizano womwe ulipo pakati pa vitamini A ndi mitundu ingapo ya khansa.
Mgwirizano wa Vitamini A Wowopsa Kwa Khansa
Kafukufuku wina waposachedwa wazachipatala awonetsa kuti zowonjezera monga beta-carotene zitha kupititsa patsogolo chiopsezo cha khansa yamapapo makamaka kwa omwe amasuta fodya komanso anthu omwe ali ndi mbiri yosuta.
Pakafukufuku wina, ofufuza a pulogalamu ya Thoracic Oncology ku Moffitt Cancer Center ku Florida, adasanthula kulumikizanaku pofufuza zopezeka pamitu 109,394 ndipo adazindikira kuti 'pakati pa omwe akusuta, beta-carotene supplementation yapezeka kuti imalumikizidwa kwambiri ndi chiwopsezo chowonjezeka cha mapapo khansa '(Tanvetyanon T et al, Cancer, 2008).
Kuphatikiza pa kafukufukuyu, maphunziro am'mbuyomu amachitiranso omwe amasuta amuna, monga CARET (Carotene ndi Retinol Efficacy Trial) (Omenn GS et al, New Engl J Med, 1996), ndi ATBC (Alpha-Tocopherol Beta-Carotene) Cancer Prevention Study (ATBC Cancer Prevention Study Group, New Engl J Med, 1994), adawonetsanso kuti kumwa kwambiri Vitamini A sikuti sikungalepheretse khansa yam'mapapo, komanso kuwonetsa kuwonjezeka kwa chiwopsezo cha khansa yamapapo pakati pa omwe atenga nawo mbali phunziroli.
Pakuwunikanso kwina kwamaphunziro 15 azachipatala omwe adasindikizidwa mu nyuzipepala yaku America ya Clinical Nutrition mu 2015, milandu yoposa 11,000 idawunikiridwa, kuti adziwe kuchuluka kwa mavitamini ndi chiwopsezo cha khansa. Kukula kwakukulu kwazitsanzo izi, ma retinol anali ophatikizidwa ndi chiopsezo cha khansa ya prostate. (Ofunika TJ et al, Am J Clin. Zakudya., 2015)
Kafukufuku wowunika wazoposa 29,000 omwe adatenga pakati pa 1985-1993 kuchokera ku kafukufuku wopewera khansa ya ATBC, adanenanso kuti pakutsata zaka zitatu, amuna omwe ali ndi vuto lalikulu la serum retinol amakhala ndi chiopsezo chachikulu cha khansa ya prostate (Mondul AM et al, Am J Epidemiol, 3). Kafukufuku waposachedwa kwambiri wokhudzana ndi NCI womwe umayendetsedwa ndi kafukufuku wopewera khansa motsatirana ndi 2011, adatsimikizira zomwe apeza kale mgwirizanowu wa serum retinol ndende yomwe ili ndi chiopsezo chachikulu cha khansa ya prostate (Hada M et al, Am J Epidemiol, 2019).
Chifukwa chake, ngakhale kuti beta-carotene yachilengedwe ndiyofunikira pakudya koyenera, kudya mopitilira muyeso wama multivitamin kumatha kukhala kovulaza ndipo sikungathandize nthawi zonse kupewa khansa. Monga momwe kafukufuku akusonyezera, kudya kwambiri kwa retinol ndi carotenoid zowonjezera kumatha kuwonjezera ngozi za khansa monga khansa yam'mapapo mwa omwe amasuta ndi khansa ya prostate mwa amuna.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Mgwirizano wa Vitamini A wokhala ndi Kuchepetsa Kuopsa kwa Khansa Yapakhungu
Kafukufuku wamankhwala adasanthula zomwe zakhudzana ndi kudya kwa Vitamini A komanso chiwopsezo cha khungu la squamous cell carcinoma (SCC), mtundu wa khansa yapakhungu, kuchokera kwa omwe atenga nawo gawo m'maphunziro awiri akulu, owonera nthawi yayitali. Maphunzirowa anali Nurses 'Health Study (NHS) ndi Health Professionals Follow-Up Study (HPFS). Cutaneous squamous cell carcinoma (SCC) ndi mtundu wachiwiri wofala kwambiri wa khansa yapakhungu yomwe imakhala pafupifupi 7% mpaka 11% ku United States. Kafukufukuyu anaphatikizira zambiri kuchokera kwa azimayi aku 75,170 aku US omwe adatenga nawo gawo pa kafukufuku wa NHS, ali ndi zaka zapakati pa 50.4, ndi amuna 48,400 aku US omwe adatenga nawo gawo pa kafukufuku wa HPFS, ali ndi zaka zapakati pa 54.3.Kim J et al, JAMA Dermatol., 2019).
Zotsatira zazikulu za kafukufukuyu ndikuti kudya kwa Vitamini A kumalumikizidwa ndi chiopsezo chochepa cha khansa yapakhungu (SCC). Gulu lomwe linali ndi Vitamini A wambiri tsiku lililonse linali ndi kuchepa kwa 17% pochepetsa SCC poyerekeza ndi gulu lomwe limadya Vitamini A. Amapezeka kwambiri kuchokera kuzakudya osati pazowonjezera zakudya. Kudya kwambiri mavitamini A, retinol, ndi carotenoids, omwe amapezeka kuchokera ku zipatso ndi ndiwo zamasamba zosiyanasiyana, kumalumikizidwa ndi chiopsezo chochepa cha SCC.
Magwero, Ubwino ndi Kuopsa kwa Vitamini B6 ndi B12 mu Cancer
magwero : Vitamini B6 ndi B12 ndi mavitamini osungunuka m'madzi omwe amapezeka muzakudya zambiri. Vitamini B6 ndi pyridoxine, pyridoxal ndi pyridoxamine mankhwala. Ndi michere yofunikira ndipo ndi coenzyme yokhudzana ndi kagayidwe kazinthu m'thupi lathu, imathandizira pakukula kwa chidziwitso, kapangidwe ka hemoglobin ndi chitetezo chamthupi. Zakudya zopatsa thanzi za Vitamini B6 zimaphatikizapo nsomba, nkhuku, tofu, ng'ombe, mbatata, nthochi, mbatata, mapeyala ndi pistachios.
Vitamini B12, yomwe imadziwikanso kuti cobalamin, imathandiza kuti mitsempha ndi maselo amwazi azikhala athanzi ndipo ndizofunikira popanga DNA. Kuperewera kwake kwa vitamini B12 kumadziwika kuti kumayambitsa kuchepa kwa magazi, kufooka komanso kutopa motero ndikofunikira kuti zomwe timadya tsiku ndi tsiku ziphatikizire zakudya zomwe zili ndi Vitamini B12. Kapenanso, anthu amagwiritsa ntchito mavitamini B owonjezera kapena B-complex kapena multivitamin zowonjezera zomwe zimaphatikizapo mavitaminiwa. Mavitamini B12 ndi nsomba ndi nyama monga mkaka, nyama ndi mazira ndi zomera ndi zomerazo monga tofu ndi zinthu zopangidwa ndi soya zopangidwa ndi thovu komanso ma seaweeds.
Mgwirizano wa Vitamini B6 wokhala ndi Khansa Pangozi
Mayeso ochepa azachipatala omwe adamalizidwa mpaka pano sanawonetse kuti kuwonjezera kwa vitamini B6 kumatha kuchepetsa kufa kapena kuthandiza kupewa khansa. Kufufuza kwa kafukufuku kuchokera ku maphunziro awiri akuluakulu azachipatala ku Norway sanapeze mgwirizano pakati pa vitamini B6 supplementation ndi matenda a khansa ndi kufa. (Ebbing M, et al, JAMA, 2009) Chifukwa chake, umboni wogwiritsa ntchito vitamini B6 kupewa kapena kuchiza khansa kapena kuchepetsa kawopsedwe kokhudzana ndi chemotherapy sizomveka kapena zomveka. Ngakhale, 400 mg ya vitamini B6 itha kukhala yothandiza kuchepetsa kuchepa kwa matenda amiyendo yamankhwala, mankhwala a chemotherapy. (Chen M, et al, PLoS One, 2013) Kuwonjezerapo vitamini B6, komabe, sikunawonetsetse kuti kumawonjezera chiopsezo cha khansa.
Mgwirizano wa Vitamini B12 wokhala ndi Khansa Pangozi
Tnazi mavuto akuchulukira pakugwiritsa ntchito Vitamini B12 yayitali komanso kuphatikiza kwake ndi chiopsezo cha khansa. Kafukufuku wosiyanasiyana adachitidwa kuti afufuze momwe mavitamini B12 amathandizira pakakhala khansa.
Kafukufuku woyeserera wazachipatala, wotchedwa B-PROOF (B Vitamini for the Prevention of Osteoporotic Fractures) woyeserera, adachitika ku Netherlands kuti awone momwe azithandizira tsiku ndi tsiku ndi vitamini B12 (500 μg) ndi folic acid (400 μg), ya 2 kwa zaka 3, pa zochitika zosweka. Zambiri kuchokera phunziroli zinagwiritsidwa ntchito ndi ochita kafukufuku kuti apitilize kufufuza momwe Vitamini B12 imathandizira pakakhala vuto la khansa kwakanthawi. Kuwunikaku kunaphatikizira zambiri kuchokera kwa omwe atenga nawo mbali pa 2524-B-PROOF ndipo adapezeka kuti folic acid ndi vitamini B12 zowonjezerapo zimakhala pachiwopsezo chachikulu cha khansa yonse komanso chiopsezo chachikulu cha khansa yoyipa. Komabe, ofufuza akuwonetsa kutsimikizira izi pakupeza kwakukulu, kuti athe kusankha ngati Vitamini B12 supplementation iyenera kungoperekedwa kwa iwo okha omwe ali ndi vuto la B12 (Oliai Araghi S et al, Cancer Epidemiol Biomarkers Prev., 2019).
Pakafukufuku wina wapadziko lonse wofalitsidwa posachedwa, ofufuzawo adasanthula zotsatira kuchokera ku kafukufuku 20 ndi kuchuluka kwa anthu omwe ali ndi khansa ya m'mapapo 5,183 ndikuwongolera kwawo 5,183, kuti awone momwe mavitamini B12 amakhudzidwira ndi chiopsezo cha khansa kudzera muyeso woyendetsera vitamini B12 mu zisanachitike matenda a magazi. Potengera kusanthula kwawo, adazindikira kuti kuchuluka kwa vitamini B12 kumalumikizidwa ndi chiopsezo chowonjezeka cha khansa yam'mapapo komanso kuchuluka kwa Vitamini B12, chiopsezo chidakwera ndi ~ 15% (Fanidi A et al, Int J Cancer., 2019).
Zotsatira zazikulu zamaphunziro onsewa zikuwonetsa kuti kugwiritsa ntchito Vitamini B12 kwa nthawi yayitali kumalumikizidwa ndi chiopsezo chowonjezeka cha khansa monga khansa yoyipa komanso khansa yamapapo. Ngakhale izi sizikutanthauza kuti timachotseratu Vitamini B12 pazakudya zathu, popeza timafunikira Vitamini B12 yokwanira ngati gawo la chakudya wamba kapena ngati tili ndi vuto la B12. Zomwe tifunika kupewa ndizowonjezera vitamini B12 supplementation (yopitilira muyeso wokwanira).
Magwero, Ubwino ndi Kuopsa kwa Vitamini C mu Khansa
magwero : vitamini C, yomwe imadziwikanso kuti ascorbic acid, imasungunuka ndi madzi, michere yofunikira yomwe imapezeka muzakudya zambiri. Ili ndi zida za antioxidant zomwe zimathandiza kuteteza maselo athu kuti asawonongedwe ndi zopitilira muyeso zaulere. Ma radicals aulere ndi mankhwala omwe amapangidwa thupi lathu likamagwiritsa ntchito chakudya ndikupangidwanso chifukwa chazowoneka zachilengedwe monga kusuta ndudu, kuipitsa mpweya kapena cheza cha ultraviolet padzuwa. Vitamini C amafunikanso ndi thupi kupanga collagen yomwe imathandizira kuchiritsa kwa bala; komanso zimathandizira kusunga chitetezo champhamvu mwamphamvu. Zakudya zomwe zili ndi Vitamini C zimaphatikizaponso zipatso monga zipatso za lalanje, zipatso za mandimu ndi mandimu, tsabola wofiira ndi wobiriwira, zipatso za kiwi, cantaloupe, strawberries, masamba a cruciferous, mango, papaya, chinanazi komanso zipatso ndi ndiwo zamasamba.
Phindu Mgwirizano wa Vitamini C wokhala ndi Khansa Pangozi
Pakhala pali maphunziro ambiri azachipatala omwe amafufuza zaubwino wogwiritsa ntchito Vitamini C wambiri mu khansa zosiyanasiyana. Mayeso okonzedwa bwino a Vitamini C omwe amagwiritsidwa ntchito ngati chowonjezera pakamwa sanapeze phindu kwa anthu omwe ali ndi khansa. Komabe, posachedwapa, Vitamini C wopatsidwa kudzera m'mitsempha wapezeka kuti akuwonetsa phindu mosiyana ndi momwe zimayambira pakamwa. Matenda awo opezeka m'mitsempha amapezeka kuti ndi otetezeka komanso kuti athandize poizoni akagwiritsidwa ntchito limodzi ndi mankhwala a radiation ndi chemotherapy.
Kafukufuku wamankhwala adachitidwa kwa odwala khansa omwe amapezeka kuti ali ndi glioblastoma (GBM), kuti awone chitetezo ndi mphamvu ya kulowetsedwa kwamankhwala a ascorbate (Vitamin C), operekedwa limodzi ndi chithandizo chamankhwala cha radiation ndi temozolomide (RT / TMZ) cha GBM. (Allen BG et al. Chipatala cha Cancer Res., 2019) Zotsatira za kafukufukuyu zikuwonetsa kuti kupatsa mavitamini C ochulukirapo kapena kukwera kwa odwala khansa ya GBM kuwirikiza kawiri kupulumuka kwawo kuyambira miyezi 12 mpaka miyezi 23, makamaka pamitu yomwe inali ndi chidziwitso chodziwika bwino. 3 mwa maphunziro a 11 anali akadali amoyo panthawi yolemba kafukufukuyu ku 2019. Zoyipa zokha zomwe anthu adakumana nazo ndi mkamwa wouma komanso kuzizira komwe kumalumikizidwa ndi kulowetsedwa kwa ascorbate, pomwe zotsatira zina zoyipa kwambiri zakutopa, mseru komanso ngakhale zovuta zoyipa zamatenda okhudzana ndi TMZ ndi RT zidachepetsedwa.
Vitamini C yowonjezeranso yawonetsanso kulumikizana ndi mankhwala a hypomethylating agent (HMA) Decitabine, chifukwa cha khansa ya myeloid leukemia. Kuyankha kwamankhwala a HMA kumakhala kotsika, pafupifupi 35-45% (Welch JS et al, New Engl. J Med., 2016). Kafukufuku waposachedwa ku China adayesa zovuta zakuphatikiza Vitamini C ndi Decitabine pa odwala khansa okalamba omwe ali ndi AML. Zotsatira zawo zidawonetsa kuti odwala khansa omwe adatenga Decitabine kuphatikiza Vitamini C anali ndi chikhululukiro chokwanira kwambiri cha 79.92% poyerekeza ndi 44.11% mwa iwo omwe adangotenga Decitabine (Zhao H et al, Leuk Res., 2018Malingaliro asayansi amomwe Vitamini C adasinthira mayankho a Decitabine mwa odwala khansa adatsimikizika ndipo sizinali mwayi wongochitika chabe.
Kafukufukuyu akuwonetsa kuti kuchuluka kwa mavitamini a Vitamini C sikungangowonjezera kulekerera kwa mankhwala a khansa, koma kumatha kukulitsa moyo wa odwala ndikuchepetsa poizoni ya ma radiation ndi chemotherapy chithandizo cha mankhwala. Mavitamini C omwe amaperekedwa pakamwa samayamwa bwino kuti akwaniritse kuchuluka kwa kulowetsedwa kwa vitamini C, motero sikunawonetse phindu. Kulowetsedwa kwambiri kwa vitamini C (ascorbate) kwawonetsanso lonjezo pochepetsa poizoni wa chemotherapies monga gemcitabine, carboplatin ndi paclitaxel mu khansa ya kapamba ndi yamchiberekero. (Welsh JL et al, Cancer Chemother Pharmacol., 2013; Ma Y et al, Sci. Tanthauzirani. Med., 2014)
Magwero, Ubwino ndi Kuopsa kwa Vitamini D mu Khansa
magwero : Vitamini D ndi chopatsa thanzi chomwe chimafunikira ndi matupi athu kuti tikhale ndi mafupa olimba pothandiza kutulutsa calcium kuchokera ku zakudya ndi zowonjezera. Zofunikanso pantchito zina zambiri zamthupi kuphatikiza kusuntha kwa minofu, kuwonetsa mitsempha ndikugwira ntchito kwa chitetezo chathu cha mthupi kuthana ndi matenda. Zakudya zomwe zili ndi Vitamini D ndi nsomba zamafuta monga saumoni, tuna, mackerel, nyama, mazira, mkaka, bowa. Matupi athu amapanganso Vitamini D pakhungu likawunikiridwa ndi dzuwa.
Mgwirizano wa Vitamini D wokhala ndi Khansa Pangozi
Kafukufuku woyembekezeredwa wazachipatala adachitidwa kuti athetse funso loti Vitamini D supplementation amathandizira kupewa khansa. Kuyesedwa kwachipatala VITAL (VITamin D ndi omegA-3 kuyesera) (NCT01169259) inali mayesero mdziko lonse, oyembekezera, osasinthika, ndi zotsatira zomwe zatulutsidwa posachedwa mu New England Journal of Medicine (Manson JE et al, Engl J Med Watsopano., 2019).
Panali anthu 25,871 omwe adachita nawo kafukufukuyu omwe adaphatikiza amuna azaka 50 kapena kupitilira ndipo akazi azaka 55 kapena kupitilira apo. Omwe adagawidwa adagawika mwachisawawa kukhala gulu lomwe limatenga Vitamini D3 (cholecalciferol) chowonjezera cha 2000 IU patsiku, yomwe ndi nthawi 2-3 ya chakudya chovomerezeka. Gulu lowongolera la placebo silinatenge zowonjezerapo Vitamini D. Palibe aliyense mwa omwe adalembetsa omwe anali ndi khansa.
Zotsatira za kafukufuku wa VITAL sizinawonetse kusiyana kulikonse pakudziwika kwa khansa pakati pa Vitamini D ndi magulu a placebo. Chifukwa chake, kuchuluka kwa mavitamini D owonjezera sikunalumikizidwe ndi chiopsezo chochepa cha khansa kapena kuchepa kwa khansa yowopsa. Chifukwa chake, kafukufuku wamkuluyu, wowonetsa mwachisawawa akuwonetsa kuti kuchuluka kwa mavitamini D owonjezera kumatha kuthandizanso pakukhudzana ndi mafupa koma kuwonjezeranso mopitilira muyeso sikukuwonjezera phindu panjira yoletsa khansa.
Magwero, Ubwino ndi Kuopsa kwa Vitamini E mu Khansa
magwero : vitamini E ndi gulu lamafuta osungunuka a antioxidant omwe amapezeka muzakudya zambiri. Zimapangidwa ndi magulu awiri am'madzi: tocopherols ndi tocotrienols, pomwe choyambirira chimakhala ndi vitamini E mu zakudya zathu. Mavitamini a vitamini E amathandiza kuteteza maselo athu kuti asawonongeke chifukwa chotsitsimutsa kwambiri komanso kupsinjika kwa oxidative. Ndikofunikira pazabwino zambiri zathanzi kuyambira chisamaliro cha khungu mpaka kusintha kwa mtima ndi thanzi laubongo. Zakudya zokhala ndi Vitamini E ndizophatikiza mafuta a chimanga, mafuta a masamba, maolivi, maamondi, mtedza, mapineti, mbewu za mpendadzuwa kupatula zipatso ndi ndiwo zamasamba zambiri. Zakudya zapamwamba mu tocotrienols ndizo mpunga, phala, rye, mafuta a mgwalangwa.
Mgwirizano wa Vitamini E wokhala ndi Khansa Pangozi
Kafukufuku wambiri wazachipatala awonetsa chiwopsezo chowonjezeka cha khansa ndi kuchuluka kwa Vitamini E.
Kafukufuku wochokera m'madipatimenti osiyanasiyana a neuro oncology ndi ma neurosurgery m'mazipatala aku US adasanthula zomwe zidafunsidwa kuchokera kwa odwala 470 omwe adachitika atazindikira kuti ali ndi khansa ya ubongo glioblastoma multiforme (GBM). Zotsatira zake zidawonetsa kuti ogwiritsa ntchito Vitamini E anali ndi kufa kwambiri poyerekeza ndi odwala khansa omwe sanagwiritse ntchito Vitamini E.Mulfur BH et al, Neurooncol Pract., 2015)
Pakafukufuku wina wochokera ku Sweden ndi Cancer Registry yaku Norway, ofufuzawo adatenga njira ina yodziwira zomwe zingayambitse khansa ya ubongo, glioblastoma. Adatenga ma seramu mpaka zaka 22 isanachitike matenda a glioblastoma ndikuyerekeza kuyerekezera kwa ma metabolite azitsanzo za seramu za iwo omwe adayambitsa khansa kuchokera kwa omwe sanatero. Anapeza ma seramu ochulukirapo a Vitamini E isoform alpha-tocopherol ndi gamma-tocopherol milandu yomwe idayamba glioblastoma. (Bjorkblom B et al, Oncotarget, 2016)
Chiyeso chachikulu kwambiri cha Selenium ndi Vitamin E Cancer Prevention Trial (SELECT) chidachitika kwa amuna opitilira 35,000 kuti awone kuwopsa kwa Vitamini E supplementation. Kuyesaku kunachitika kwa amuna omwe anali azaka 50 kapena kupitilira ndipo omwe anali ndi otsika a prostate enieni a antigen (PSA) a 4.0 ng / ml kapena ochepera. Poyerekeza ndi omwe sanatenge mavitamini E (Placebo kapena gulu lofotokozera), kafukufukuyu adapeza chiwopsezo chachikulu cha khansa ya prostate mwa omwe amatenga zowonjezera mavitamini E. Chifukwa chake, zakudya zowonjezera mavitamini E zimalumikizidwa ndi chiopsezo chowonjezeka cha khansa ya prostate pakati pa amuna athanzi. (Klein EA et al, JAMA, 2011)
Mu alpha-tocopherol, beta-carotene kafukufuku wa khansa ya ATBC yopangidwa ndi amuna omwe amasuta fodya azaka zopitilira 50, sanapeze kuchepa kwa khansa ya m'mapapo patatha zaka zisanu mpaka zisanu ndi zitatu zowonjezera zakudya ndi alpha-tocopherol. (Engl J Med watsopano, 1994)
Ubwino wa Vitamini E mu khansa ya Ovarian
Pankhani ya ovarian khansa, Vitamini E pawiri tocotrienol wasonyeza ubwino pamene ntchito limodzi ndi muyezo chisamaliro mankhwala bevacizumab (Avastin) odwala amene kugonjetsedwa ndi chemotherapy mankhwala. Ofufuza ku Denmark, adaphunzira zotsatira za gulu la tocotrienol la Vitamini E kuphatikiza ndi bevacizumab mwa odwala khansa ya ovarian omwe sanayankhe chithandizo chamankhwala. Phunziroli linaphatikizapo odwala 23. Kuphatikiza kwa Vitamini E/tocotrienol ndi bevacizumab kunawonetsa kawopsedwe wochepa kwambiri mwa odwala khansa ndipo anali ndi 70% kukhazikika kwa matenda. (Thomsen CB et al, Pharmacol Res., 2019)
Magwero, Ubwino ndi Kuopsa kwa Vitamini K mu Khansa
magwero : Vitamini K ndi michere yayikulu yomwe imafunika kuti magazi aziundika ndi mafupa athanzi, kupatula ntchito zina zambiri mthupi. Kuperewera kwake kumatha kuyambitsa mavuto ndi kutaya magazi. Amapezeka mwachilengedwe m'ma zakudya ambiri kuphatikiza masamba obiriwira ngati sipinachi, kale, broccoli, letesi; m'mafuta a masamba, zipatso monga ma blueberries ndi nkhuyu komanso munyama, tchizi, mazira ndi nyemba za soya. Pakadali pano palibe umboni wazachipatala wokhudzana ndi Vitamini K wokhala ndi chiopsezo chowonjezeka kapena chotsika cha Cancer.
Kutsiliza
Kafukufuku wosiyanasiyana wosiyanasiyana wazachipatala akuwonetsa kuti kudya mavitamini ndi michere monga zakudya zachilengedwe, zipatso, ndiwo zamasamba, nyama, mazira, zopangidwa ndi mkaka, tirigu, mafuta ngati gawo la chakudya chopatsa thanzi, ndi chomwe chimatipindulitsa kwambiri. Kugwiritsa ntchito kwambiri ma multivitamini kapena mavitamini owonjezerawa sikunawonetse kuti kukuwonjezera phindu popewa chiopsezo cha khansa, ndipo kumatha kubweretsa mavuto. Nthawi zambiri, kafukufukuyu apeza kuti mgwirizano wamavitamini kapena ma multivitamini omwe ali ndi chiopsezo chachikulu cha khansa. Pazifukwa zina zokha monga Vitamini C kulowetsedwa kwa odwala khansa omwe ali ndi GBM kapena Leukemia kapena kugwiritsa ntchito tocotrienol / vitamini E mwa odwala khansa ya ovari kwawonetsa phindu pakukonza zotsatira ndikuchepetsa zoyipa.
Chifukwa chake, umboni wasayansi ukuwonetsa kuti kugwiritsa ntchito mavitamini ndi ma multivitamin mopitilira muyeso sikothandiza pakuchepetsa chiopsezo cha khansa. Ma multivitamin supplements amayenera kugwiritsidwa ntchito ngati khansa pamalangizo ochokera kwa akatswiri azachipatala moyenera. Chifukwa chake mabungwe kuphatikiza Academy of Nutrition and Dietetics, American Cancer Society, American Institute of Cancer Research ndi American Heart Association salimbikitsa kugwiritsa ntchito zakudya zowonjezera kapena ma multivitamini oteteza khansa kapena matenda amtima.
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo komanso kuyang'ana njira zina zochiritsira khansa chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.