o ka Naauao
ʻO ka lawe ʻana i nā meaʻai kūpono a me nā mea hoʻohui ma ke ʻano he ʻāpana o ka meaʻai e pili ana i ka omega-3 fatty acids, nā meaʻai meaʻai waha kikoʻī, nā mea kanu a me nā huaʻai, folate, fiber insoluble, Vitamin C, salicylates maoli, nā mea kanu allium, limu, kelp a me ka inu kofe ke kōkua i ka hōʻemi. ka pilikia o ka cholangiocarcinoma / bile duct cancer a i ʻole e hoʻomaikaʻi i ka cachexia pili i ka maʻi kanesa a me nā hōʻailona ʻē aʻe a me nā hōʻailona i nā maʻi cholangiocarcinoma. Eia nō naʻe, ʻo ka ʻai ʻana i ka waiʻona a me ka puhi paka, ka mōʻaukala ʻohana o ka maʻi kanesa, ka momona, me nā meaʻai e like me ka iʻa cyprinoid maka, nā meaʻai nitrate kiʻekiʻe, nā mea kanu i mālama ʻia a me nā ʻiʻo paʻakai ma ke ʻano o ka meaʻai a me ka mālama ʻana i nā ilo kikoʻī hiki ke hoʻonui i ka pilikia o ka bile duct cancer/cholangiocarcinoma a pono e pale aku. Eia kekahi, ʻo ka lawe ʻana i ka Vitamin D3 ma ke ʻano he ʻāpana o ka meaʻai me kekahi mau chemotherapies hiki ke hoʻonui i ka lāʻau ʻona i hoʻokomo ʻia i nā maʻi cholangiocarcinoma. No laila, e pale i kēia mau meaʻai a me nā mea hoʻohui e hōʻemi i ka pilikia, ka ʻawaʻawa a me ka hoʻomaikaʻi ʻana i nā hopena lapaʻau i ka maʻi bile duct / cholangiocarcinoma. No laila, he mea nui e hoʻopilikino i ka meaʻai i ka kikoʻī Ka maʻi 'aʻai ʻano a me nā mea e pili ana i ke ʻano o ke ola, ke kaumaha o ke kino, nā meaʻai allergies, a me ka mālama mau ʻana, e loaʻa ai nā pōmaikaʻi a noho palekana.
He aha ka Cholangiocarcinoma a i ʻole ʻo Bile Duct Cancer?
ʻO ka maʻi ʻaʻaʻa Bile duct, i ʻike ʻia ʻo Cholangiocarcinoma, he maʻi ʻaʻai ia i hoʻomaka i loko o nā hunaola e uhi ana i nā kaola o ka bile, ʻo ia nā paipu liʻiliʻi e hoʻopili i ke ake i ka ʻōpū liʻiliʻi. ʻOhi nā aʻa oʻa i hōʻiliʻili ʻia e ke akepaʻa, hoʻokahe iā ia i ka paepae a i loko o ka ʻōpū liʻiliʻi, kahi e kōkua ai ia e hoʻowali i nā momona i ka meaʻai.
ʻO ka maʻi ʻaʻai Bile duct / Cholangiocarcinoma kahi ʻano maʻi ʻaʻai ʻole, me he 8000 mau hihia hou i ʻike ʻia ma ʻAmelika Hui Pū ʻIa i kēlā me kēia makahiki, ka hapanui o ka poʻe i piha nā makahiki he 70. (ʻAmelika Hui Pū ʻIa ʻAmelika) ʻO ka helu ola 5 mau makahiki o cholangiocarcinoma ma waena o 2 -30%.
He aha nā ʻano ʻokoʻa o Cholangiocarcinoma?
Ma muli o kahi e kū ai kēia maʻi ʻaʻai i loko o ka ʻōnaehana kahena o ka bile, ua hoʻokaʻawale ʻia ʻo cholangiocarcinoma i ʻelua:
- ʻO ka maʻi ʻaʻai Intrahepatic bile duct - e hoʻopili ai i nā aʻa o ka bile i loko o ke ake
- Ka maʻi ʻaʻai ʻo Extrahepatic bile duct - i loko o nā aʻa aʻa i waho o ke ake.
Pili pinepine ʻia ʻo Intrahepatic cholangiocarcinoma me kahi wānana ʻoi aku ka maikaʻi ke hoʻohālikelike ʻia me ka extrahepatic cholangiocarcinoma.
Hoʻokaʻawale hou ʻia nā maʻi ʻalekole bile Extrahepatic i nā ʻano aʻe.
- Extrahepatic perihilar bile duct cancer maʻi ʻaʻai - a kū ia ma waho o ke akepaʻa a aia ma ke kiko o ke akepaʻa kahi e puka ai nā aʻa aʻa.
- ʻO Distal extrahepatic bile duct cancer maʻi ʻaʻai - i kū ma waho o ke ake e kokoke ana i ka ʻōpū, kahi e komo ai nā aʻa aʻa i ka ʻōpū i kapa ʻia ka ampulla o Vater
He aha nā hōʻailona a me nā ʻōuli o Bile Duct Cancer a i ʻole Cholangiocarcinoma?
ʻO nā ʻōuli a me nā ʻōuli i ʻike ʻia i ka mea maʻi me ka maʻi ʻaʻai bile duct hiki ke loli ma muli o kahi o ka maʻi ʻaʻai. I ka wā o ke kaʻina mua, ʻaʻole hōʻike nā ʻōpala maʻi maʻi palapū i nā hōʻailona a me nā ʻōuli. Hoʻomaka hoʻomaka ʻo Cholangiocarcinoma e hōʻike i nā ʻōuli ma ka hoʻomaka ʻana o ke kahe o ka bile i mea keakea ʻia, i kahi wā i ʻoi aku ka holomua, ma muli o ka hōʻike pinepine ʻia ʻana o nā maʻi maʻi maʻi maʻi i nā mea maʻi i ka wā o ka diagnostics.
ʻO kekahi o nā hōʻailona a me nā ʻōuli o cholangiocarcinoma a i ʻole ka maʻi ʻaʻai bile e komo pū me:
- Jaundice - Yellowing o keʻokeʻo o nā maka a me kaʻili
- ʻIli ʻili
- ʻO ka mimi ʻeleʻele a me nā pā paler
- Ka hoʻemi kaumaha i manaʻo ʻole ʻia
- Ka luhi a me ka nāwaliwali maʻamau
- ʻO ke kuni kiʻekiʻe a me ke anuanu
- ʻO kaʻehaʻeha
- E ʻeha nei
He aha nā mea e mālama ai no ka maʻi ʻo Bile Duct Cancer a i ʻole Cholangiocarcinoma?
ʻO ka pae o ka maʻi ʻaʻai bile kaukaʻi ʻia i nā kumu like ʻole e like me ka wahi o ka maʻi ʻaʻai i nā aʻa o ka bile, ka nui o ka tumo a me ka nui o ka hoʻolaha / metastasis.
ʻO ka mālama ʻana no ka maʻi ʻaʻai bile ma muli o ke kahua o ka maʻi ʻaʻai, kahi i loaʻa ai ka maʻi ʻaʻai, ke olakino laulā o ka mea maʻi a inā hiki ke wehe ʻia loa e ke ʻoki. Ma waho o ke kahakaha, chemotherapy a me radiotherapy kekahi regimens lapaʻau i hoʻohana ʻia no ka maʻi ʻaʻai bile duct. ʻAʻole kuhi ʻia nā ʻano lāʻau ʻē aʻe e like me ka hoʻomaʻamaʻa palliative i ka mālama ʻana i ka maʻi ʻaʻai, akā no ka hoʻomaikaʻi ʻana i ka maikaʻi o ke ola. Hoʻohana ʻia ka lāʻau Photodynamic e hoʻoliʻiliʻi i ka tumo a kāohi i nā ʻōuli o cholangiocarcinoma / maʻi ʻaʻai bile. Ma hope o ka papaʻai me nā meaʻai kūpono a me nā mea hoʻopihapiha he mea nui e hōʻemi i nā ʻōuli a hoʻomaikaʻi i nā hopena lapaʻau ma cholangiocarcinoma / bile duct cancer maʻi.
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
He aha ke kuleana o ka papaʻai / meaʻai i ka maʻi ʻaʻai Bile Duct?
Ua hana nā kānaka noiʻi ma ka honua holoʻokoʻa i nā noiʻi like ʻole e loiloi i ka hopena o ka lawe ʻana o nā meaʻai like ʻole a me ka papaʻai i nā maʻi maʻi maʻi bile duct / cholangiocarcinoma i loaʻa i ka lāʻau lapaʻau a me ka hui pū ʻana o nā ʻano meaʻai me ka pilikia o ka maʻi ʻaʻai bile. Ma muli o kekahi o nā haʻawina preclinical, observational a me clinical, eia nā hiʻohiʻona o kekahi mau meaʻai i hōʻike ʻia he maikaʻi a maikaʻi ʻole paha, ke hiki mai i ka maʻi ʻaʻai bile.
Nā noiʻi e pili ana i ka hopena o nā meaʻai like ʻole / ʻai like ʻole i nā mea maʻi maʻi maʻi maʻi Bile Duct
Hoʻopili pū ʻia me ka Omega-3 Fatty Acid i ka Diet o Bile Duct Cancer / Cholangiocarcinoma Patients e hiki ke pono
Ua loiloi nā kānaka noiʻi mai ke Kula ʻo Medicine ʻo Jikei University ma Iapana i ka ʻikepili mai ka 27 mau maʻi maʻi maʻi pancreatic a me ka bile duct cancer i hana i ka chemotherapy ma waena o Nowemapa 2014 a me Nowemapa 2016 a hāʻawi ʻia lākou i kahi komo (ka lawe ʻana i ka meaʻai ma o ka ʻaoʻao gastrointestinal) nutrient e pili ana i ka momona omega-3 ʻakika a loaʻa i loko o nā maʻi āpau he 27, ua hoʻonui ka nui o nā iwi iwi i ka hoʻomaka ʻana o ka omega-3-fatty acid i ka hoʻohālikelike ʻia me ka mea ma mua o ka hoʻohui o kēia mea momona. (Kyohei Abe et al, Anticancer Res., 2018)
No laila, e like me ka omega-3 fatty acid ma ke ʻāpana o ka cholangiocarcinoma / dile dile maʻiʻai o ka maʻi ʻaʻai ʻoiai ke lawelawe nei i kahi ʻano kūikawā e pono paha i ka hoʻomaikaʻi ʻana i ka nāwaliwali e pili ana i ka nāwaliwali a i ʻole cachexia.
ʻOi aku ka maikaʻi o nā mea kōkua oral oral (ONS) i hoʻohana ʻia i nā maʻi maʻi ʻaʻai ʻo Bile Duct e hele ana ma Chemo
I loko o kahi noiʻi noiʻi i hana ʻia e nā mea noiʻi mai ke Kulanui ʻo Yonsei ma Seoul, Korea, ua loiloi lākou i nā hopena o nā mea hoʻopihapiha hoʻopuka waha (ONS) ma nā maʻi maʻi pancreatic a me nā maʻi ʻaʻai / cholangiocarcinoma i loaʻa i ka maʻi chemotherapy a loaʻa iā ONS e hoʻohana ana (ma ke ʻano he papaʻai. ) hoʻomaikaʻi i ke kūlana nutritional o kēia mau maʻi ma ka hoʻonui ʻana i ke kaumaha o ke kino, ka nui momona ʻole, ka nui o nā iwi iwi, ka nui o nā kino o ke kino, a me nā momona momona, ʻoi aku hoʻi i ka poʻe e hele ana i ka pōʻaiapuni mua o ka chemotherapy, a hoʻoliʻiliʻi paha i nā ʻōnaehana luhi. (Seong Hyeon Kim et al, Nā Nutrients., 2019)
Hiki i ka Co-Use of Vitamin D3 a me kekahi mau Chemotherapies ke hoʻonui i ka inu ʻawa Chemo-i hoʻokomo ʻia i nā maʻi Cholangiocarcinoma.
I loko o kahi noiʻi i hana ʻia e nā mea noiʻi mai ke Kulanui ʻo Khon Kaen ma Thailand, ua loiloi ka poʻe noiʻi i ka ʻona a me ka hoʻomanawanui ʻana i ka lāʻau CAL -active form intermittent-high o ka Vitamin D3 i nā mea maʻi cholangiocarcinoma intrahepatic intrahepatic (CCA) a me ka pono o ka hoʻōla olakino o nā hui o ʻO ka lāʻau Vitamin3 D5 a me 3-FU i hoʻokumu ʻia i nā lāʻau chemotherapeutic. Ua ʻike ʻia ka noiʻi ua palekana ʻo Wikamina D3 a ʻae maikaʻi ʻia i nā mea maʻi cholangiocarcinoma intrahepatic holomua, akā naʻe, ʻo ka mālama pū ʻana o ka Vitamin D5 me nā lāʻau chemo 2012-FU i hoʻonui ʻia i ka lāʻau ʻona a no laila pono e hōʻalo ʻia i ka papaʻai o kēia mea maʻi. . (Aumkhae Sookprasert et al, Asian Pac J Ka maʻi ʻaʻai Prev., XNUMX)
ʻO nā haʻawina e pili ana i nā meaʻai / Diet / Life-Style ʻokoʻa a me ka hopena o ka maʻi ʻaʻai Bile
ʻO ka ʻai ʻana i nā mea kanu / hua, Folate, fiber fibolle a me Vitamin C hiki ke hoʻēmi i ka makaʻu o Extrahepatic Bile Duct Cancer.
I loko o kahi noi cohort prospective cohort e pili ana i ka lehulehu ma Iapana e pili ana i ka poʻe 80,371 mai 45 a 74 mau makahiki, ua loiloi nā mea noiʻi mai ke Kulanui ʻo Osaka, Ke Kula Nui o ke Kula Nui ʻo Sagami Women a me ka National Cancer Center ma Iapana i ka hui pū ʻana o nā mea kanu / hua me nā pilikia o maʻi kanamai pā, Ka maʻi 'aʻai a me nā maʻi maʻi maʻi extrahepatic bile duct cancer. I loko o ka wā i ukali ʻia, ua hōʻike ʻia he maʻi ʻaukā 133 gallbladder, 99 a me nā maʻi ʻaʻai he 161 extrahepatic bile duct. (Takeshi Makiuchi et al, Int J Cancer., 2017)
Ua ʻike ʻia ka haʻawina e hoʻohālikelike ʻia i ka poʻe me ka liʻiliʻi o ka ʻai ʻana i nā mea kanu a me nā huaʻai, ʻo ka poʻe me ka ʻai nui loa he 51% ka emi ʻana o ka maʻi maʻi maʻi maʻi bile duct extrahepatic. Eia hou, ua loaʻa i ka haʻawina ka emi ʻana o ka pilikia o ka extrahepatic cholangiocarcinoma me ka folate, insoluble fiber a me ka Vitamin C intake, akā naʻe, ʻaʻole i ʻike ʻia kēia mau hopena pale i ka gallbladder a me ka intrahepatic bile duct. maʻi pū.
Lawe paha i nā mea kanu Allium, Seaweed a me Kelp e hoʻemi, a mālama ʻia nā mea kanu a me nā ʻai paʻakai i mea e hoʻonui ai i ka maʻi maʻi ʻaʻai Bile.
ʻO ka loiloi ʻana i ka ʻikepili mai kahi noiʻi hihia-ka nānā ʻana i ka lehulehu ma Shanghai, Kina e ka National Cancer Institute, ma Maryland, ʻAmelika Hui Pū ʻIa a me nā hui ʻē aʻe i ka US a me Kina, ua ʻike ʻia ka lawe ʻana i nā mea kanu allium e like me nā aniani, kālika a me nā bawang. hiki i ka limu a me ke kelp ke hoʻemi i ka makaʻu o nā maʻi ʻeha biliary e like me ka maʻi ʻaʻai gallbladder, cholangiocarcinoma extrahepatic a me ampulla o nā maʻi ʻo Vater. Eia nō naʻe, ua ʻike ʻia kahi noiʻi i ka loaʻa ʻana o nā mea kanu i mālama ʻia a me nā ʻai paʻakai i mea e hoʻonui ai i ka makaʻu o kēia mau maʻi maʻi maʻi. (Shakira M Nelson et al, PLoS Hoʻokahi., 2017)
Hiki i ka ʻai ʻana ke kī ke hōʻemi i ka makaʻu o Cholangiocarcinoma
ʻO nā kānaka noiʻi mai ka Chinese Academy of Medical Science a me ke Kulanui Lapaʻau ʻo Peking Union, ka Halemai Hoʻohui ʻ Firstlelo mua o ke Kulanui Lapaʻau o Kina, a me ke Kulanui o Macau i Kina i hana i kahi ʻano hana-ʻākoakoa o nā noiʻi nānā i paʻi ʻia i loaʻa ma o ka noiʻi palapala ma PubMed, EMBASE, a me ISI. Pūnaewele ʻepekema i paʻi ʻia ma mua o ʻOkakopa 2016 e loiloi i ka hui ma waena o ka ʻai ʻana a me ka hopena o ka maʻi ʻaʻai biliary (ʻo ia pū kekahi me cholangiocarcinoma). Ua ʻike ʻia ka noiʻi ua hoʻohālikelike ʻia i ka poʻe inu ʻole i ke kī, ua hōʻemi nui ʻia ka hanana o ka maʻi ʻaʻai biliary ma kahi o 34% i ka poʻe i ʻai i ke kī, me ka hopena i ʻoi aku ka nui i nā wahine. (Jianping Xiong et al, Oncotarget., 2017)
ʻAʻole pili paha ka inu kope me ka makaʻu o nā ʻōpala Biliary Tract
Nānā nā kānaka noiʻi mai nā Kulanui like ʻole ma ʻItalia, Polani a me ke Aupuni Hui Pū ʻIa i ka pilina ma waena o ka lawe ʻana i ka kope a me nā maʻi ʻaʻai biliary (ʻo ia hoʻi ʻo cholangiocarcinoma a i ʻole ka maʻi ʻaʻai bile) a me ka maʻi ʻaʻai maʻi ʻōpū, e pili ana i nā noi he 5 e pili ana i ka maʻi ʻaʻai Biliary tract a me 13 mau noiʻi e pili ana i ka maʻi ʻaʻai. , i loaʻa ma o ka ʻimi moʻokalaleo i ka ʻikepili pūnaewele PubMed a me EMBASE a hiki i Malaki 2017. (Justyna Godos et al, Nutrients., 2017)
Ua ʻike ʻia ka noiʻi ʻaʻole hiki i ka hoʻonui ʻia ʻana o ke kofe ke hoʻopili ʻia me nā maʻi ʻeha biliary me cholangiocarcinoma, akā naʻe, ua emi ka hopena o ka maʻi ʻaʻai ate me ka lawe nui ʻana o ke kope.
Hiki i ka Green Tea Intake ke hōʻemi i ka makaʻu o nā ʻōpala Biliary Tract
I loko o kahi noiʻi cohort prospective prospective heluna kanaka ma Iapana, nā mea noiʻi mai ke Kulanui ʻo Osaka, ke Kulanui Wahine ʻo Sagami a me ka National Cancer Center, ua loiloi ʻo Iapana i ka hui ʻana o ke kī ʻōmaʻomaʻo (ke kī ʻōmaʻomaʻo piha, Sencha, a me Bancha / Genmaicha) a me ka ʻai kope me ka makaʻu no nā maʻi ʻaʻai biliary. Ua ʻike ʻia ka noiʻi ʻana e pili ana kahi inu kī ʻōmaʻomaʻo kiʻekiʻe me ka hoʻemi ʻia o ka makaʻu o ka maʻi ʻaʻai biliary, me ka hopena i ʻoi aku ka nui i ka ʻai ʻana a Sencha. (Takeshi Makiuchi et al, maʻi kanesa sci., 2016)
ʻO ka ʻai ʻana i nā pā iʻa maka e pili ana i ka Fluke Hānai (Worm Parasitic) hiki i ka maʻi ke hoʻonui i ka makaʻu o Cholangiocarcinoma
Ua mālama ʻia kahi noiʻi wehewehe wehewehe ʻāpana e nā mea noiʻi mai ke Kulanui ʻo Suranaree ma Thailand i loiloi ʻia ka lawaiʻa iʻa e pili ana i ka fluke ate (worm parasitic) ma waena o ka heluna kanaka no ka opisthorchiasis (kahi maʻi parasite i hoʻokumu ʻia e nā lāhui i ka genus Opisthorchis) a cholangiocarcinoma ma Nakhon Ratchasima Province, Thailand. Ua hoʻohana ka noiʻi i nā nīnau nīnau papaʻai e pili ana i ka ʻike mai ka poʻe i loaʻa nui i ka cholangiocarcinoma a ʻike he 78% o kēia mau mea i komo i ka wā i hala o ka hoʻohana ʻana i ka iʻa maka. Ua ʻike ʻia ua hoʻopaʻa ʻia kekahi mau kīʻaha e pili ana i ka maʻi fluke o ka ate e ka poʻe i makaʻu nui i ka cholangiocarcinoma, ka iʻa hānai maka, ma lalo o ka iʻa i puhi ʻia, iʻa iʻa iʻa maka, a me nā salakeka iʻa iʻa miko maka. (Wasugree Chavengkun et al, 'Ākia Pac J Ka maʻi' aʻai Prev., 2016)
Hiki i ka puhi ʻana ke hoʻonui i ka makaʻu o Cholangiocarcinoma
ʻO kahi loiloi ʻōnaehana o 26 prospective Studies me 1391 gallbladder, 758 intrahepatic bile duct, 1208 extrahepatic bile duct, a me 623 ampulla o nā maʻi kanesa Vater i hōʻike ʻia i loko o ka wā i ukali ʻia e pili ana i ka hoʻonui ʻia ka makaʻu i ke kahena o ka bili extrahepatic a me ka ampulla o nā maʻi ʻo Vater. Ua ʻike ʻia ke aʻo ʻana i ka hoʻohālikelike ʻia me ka poʻe i puhipaka ʻole ʻole, ka poʻe i puhipaka> 40 mau paka i kēlā lā i kēia lā e pili ana me ka nui o ka makaʻu o Intrahepatic Cholangiocarcinoma. (Emma E McGee et al, J Natl Cancer Inst., 2019)
ʻO kekahi noiʻi i hana ʻia e nā mea noiʻi mai ke Kulanui ʻo Zhejiang ma Kina i loaʻa i ka puhipaka ʻana, akā ʻaʻole hiki ke hoʻopili ʻia ka wai ʻona me ka nui o ka hopena o ka extrahepatic cholangiocarcinoma. (Xiao-Hua Ye et al, World J Gastroenterol., 2013)
ʻO ka ʻai ʻana o ka iʻa ʻo Cyprinoid maka, Nā meaʻai Nitrate kiʻekiʻe, ʻona, a me kahi lāʻau anti-worm kikoʻī e hoʻonui ai i ka Cholangiocarcinoma Risk
Ua hana ʻia kahi hana e nā kānaka noiʻi mai ke Kulanui ʻo Khon Kaen ma Thailand i nā kumuhana no ka cholangiocarcinoma ma Thailand e pili ana i nā noiʻi i loaʻa mai nā pūnaewele pūnaewele e like me SCOPUS, Pro Quest, Science Direct, PubMed, a me ka papa inoa komo ākea ākea o Khon Kaen. Kulanui mai 2016. Ua loaʻa kahi noiʻi i kahi pilina koʻikoʻi ma waena o cholangiocarcinoma a me nā kumu e like me ka makahiki, ka maʻi ʻo Opisthorchis viverrini (kahi maʻi parasite i hoʻokumu ʻia e nā ʻano i ka genist Opisthorchis), ʻai ʻana i ka iʻa cyprinoid maka, ka moʻolelo ʻohana o ka maʻi ʻaʻai, ka inu lama, a me ka lawe ʻana i lāʻau kūikawā anti-worm. (Siriporn Kamsa-ard et al, Asian Pac J Cancer Prev., 2018)
Ma kekahi loiloi systematic i hana ʻia e nā mea noiʻi mai ke Kulanui ʻo Tufts ma ʻAmelika Hui Pū ʻIa a me nā ʻoihana ʻē aʻe ma Kanada, Kina a me Italia, ua hōʻike lākou i ka hoʻohui ʻana i ka Opisthorchis viverrini / ate fluke, ka waiʻona a me ka puhi paka, ka mōʻaukala ʻohana o Ka maʻi 'aʻai, me nā iʻa cyprinoid maka a me nā meaʻai nitrate kiʻekiʻe ma ke ʻano he ʻāpana o ka meaʻai, a pili pū kekahi lāʻau ilo kikoʻī me ka piʻi nui ʻana o ka cholangiocarcinoma/bile duct cancer. (Jennifer A Steele et al, Infect Dis Poverty., 2018)
Hiki i ka ʻai ʻana i ka meaʻai fermented ke hōʻeha i nā mea pilikia o ka Opisthorchiasis e pili pū ʻia me Cholangiocarcinoma (maʻi parasite) - Study Preclinical
ʻO kahi noiʻi preclinical i hana ʻia e nā mea noiʻi mai ke Kulanui ʻo Technology ʻo Rajamangala ISAN a me ke Kulanui ʻo Khon Kaen ma Thailand i ʻike ʻia i ka ʻai ʻana i nā meaʻai i hū ʻia e like me ka pla som-iʻa i hū ʻia no ka lā 1, kahi pipi i hānai ʻia, a me nā mea kanu i hana ʻia me phag, a me hiki ke hoʻonui i ka ra-iʻa no 6 mau mahina hiki i ka cholangitis a me ka cholangiofibrosis, nā kumu pilikia nui no ka opisthorchiasis e pili ana i ka cholangiocarcinoma (kahi maʻi parasite). (Pranee Sriraj et al, Parasitol Res., 2016)
ʻO ka Salicylate kūlohelohe i loko o nā meaʻai e hōʻemi i ka makaʻu o Cholangiocarcinoma
Ua alakaʻi nā kānaka noiʻi mai ka Chinese Academy of Medical Science and Peking Union Medical College (CAMS & PUMC), Kina, i kahi ʻōnaehana loiloi a me nā meta-analysis o nā noiʻi i loaʻa ma o ka ʻimi palapala ʻana ma PubMed, EMBASE, a me ka Pūnaewele ʻepekema ISI a hiki i ʻOkakopa 2017, e pili ana 12,535 cholangiocarcinoma hihia a me 92,97,450 mau olakino olakino a loaʻa i ka salicylate / aspirin hoʻokele e hoʻoliʻiliʻi i ka makaʻi o cholangiocarcinoma e 31%, keu hoʻi i ka intrahepatic cholangiocarcinoma. (Jianping Xiong et al, Cancer Manag Res., 2018)
No laila, ʻo kahi papaʻai pū me nā meaʻai i loaʻa ka salicylate kūlohelohe e like me apricots, broccoli, thyme a me rosemary paha he mea maikaʻi no ka hōʻemi ʻana i ka makaʻi o cholangiocarcinoma.
Hiki i ka momona a me ka momona ke hoʻonui i ka hopena o Cholangiocarcinoma
Ua hana ʻia kahi meta-analysis e nā kānaka noiʻi mai ka Jiangxi Science and Technology Normal University a me ke Kula Nui ʻo Science a me Technology ʻo Huazhong, Kina e pili ana i ka 14 prospective cohort Studies and 15 case-control haʻawina e pili ana me 11,448,397 i komo (6,733 maʻi me ka maʻi ʻaʻai gallbladder [GBC] a 5,798 maʻi me ka extrahepatic bile duct cancer [EBDC] / Cholangiocarcinoma) i ʻike ʻia e pili ana ke kaupaona o ke kino (Obesity / Overweight) me ka piʻi nui ʻana o ka maʻi kanesa o ka bile dhe extrahepatic. (Liqing Li et al, Obesity (Kālā Puna)., 2016)
I loko o kahi noiʻi pan-European ʻē aʻe e pili ana i nā kāne a me nā wahine 467,336, ua ʻike nā mea noiʻi hiki ke hoʻopili ʻia kahi hana kino kiʻekiʻe me kahi hoʻemi hoʻemi o ka hoʻomohala ʻana i nā maʻi maʻi ate. Eia naʻe, ʻaʻole i loaʻa iā lākou kahi pilina koʻikoʻi ma waena o ka hoʻoikaika kino a me ka maʻi cholangiocarcinoma (Sebastian E Baumeister et al, J Hepatol., 2019)
ʻAʻole pili paha ka hoʻohana ʻana i nā mea inu momona a me nā wai me ka Pilikia o Biliary Tract Cancers / Cholangiocarcinoma
Ua nānā ʻia kahi noiʻi ʻana o ka European Prospective Investigation into Cancer and Nutrition Cohort study i nā pilina ma waena o ka inu ʻana i nā mea inu ʻoluʻolu (ʻono ʻono a me nā mea ʻono) a me nā huaʻai a me nā wai huaʻai a me ka pilikia o ka ate carcinoma, intrahepatic bile duct/cholangiocarcinoma a me ka ʻāpana biliary. maʻi pū e hoʻohana ana i ka ʻikepili mai 477,206 mau mea komo mai 10 mau ʻāina ʻEulopa. ʻAʻole i loaʻa i ka haʻawina ka pilina koʻikoʻi ma waena o ka inu ʻana i ka inu ʻoluʻolu a me ka pilikia o ka intrahepatic bile duct/cholangiocarcinoma. (Magdalena Stepien et al, Eur J Nutr., 2016)
ʻAʻole hiki i ka Zinc Intake ke hōʻemi i ka makaʻu o Cholangiocarcinoma
Ua ʻike ʻia kahi noiʻi kaohi hihia o ka European Prospective Investigation i ka maʻi ʻaʻai a me ka Nutr i loaʻa i ka hoʻonui ʻia ʻana o nā pae Zinc me ka hoʻemi ʻia ʻana o ka maʻi kanesa ate, akā ʻaʻole i loaʻa kahi hui me cholangiocarcinoma. (Stepien M wt al, Br J Kanesa, 2017)
Panina
ʻO nā haʻawina like ʻole i manaʻo ʻia ʻo ka lawe ʻana i nā waikawa momona omega-3, nā meaʻai meaʻai waha, nā mea kanu a me nā huaʻai, folate, fiber insoluble a me ka huaora C, salicylates maoli, nā mea kanu allium, limu, kelp a me ka inu kofe ma ke ʻano he ʻāpana o ka meaʻai hiki ke kōkua i ka hōʻemi ʻana i ka pilikia. ʻo ka maʻi ʻaʻai bile duct/cholangiocarcinoma a i ʻole e hoʻomaikaʻi paha Ka maʻi 'aʻai cachexia pili i nā maʻi cholangiocarcinoma. Eia nō naʻe, ʻo ka momona, ka ʻai ʻana i ka waiʻona a me ka puhi paka, ka moʻolelo ʻohana o ka maʻi kanesa, me ka iʻa cyprinoid maka, nā meaʻai nitrate kiʻekiʻe, nā mea kanu i mālama ʻia a me nā ʻiʻo paʻakai ma ke ʻano o ka meaʻai, a me ka lāʻau ilo kikoʻī hiki ke hoʻonui i ka pilikia o ka cholangiocarcinoma/bile duct cancer. Ma hope o ka ʻai anti-inflammatory e komo pū ana me nā huaʻai a me nā mea kanu, mālama i ke kaumaha olakino, ka hoʻohana ʻana i ke ʻano ola kino a me ka hana maʻamau e pono e haʻalele i ka maʻi bile duct / cholangiocarcinoma.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.
ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy kahi e hoʻopili ai i ko lākou ola o ke ola a nānā i nā hoʻoponopono ʻokoʻa no ka maʻi ʻaʻai. Lawe ana i ka ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.