labarai
Silymarin na bioactive daga ganye- Milk Thistle, wani maganin antioxidant ne kuma an nuna yana da wasu fa'idodi. ciwon daji marasa lafiya irin su cardio-protective effects ta hanyar rage oxidative danniya. Amfani da Milk Thistle mai aiki Silymarin tare da Doxorubicin yana amfanar yara masu fama da cutar sankarar bargo ta hanyar rage Doxorubicin-induced cardiotoxicity kamar yadda aka nuna a cikin binciken asibiti tare da yara masu cutar sankarar lymphoblastic mai tsanani.
Doxorubicin Chemotherapy & Cardiotoxicity a cutar sankarar bargo
Doxorubicin magani ne na chemotherapy wanda aka yarda don amfani dashi azaman ma'auni na kulawa a yawancin alamun cutar kansa ciki har da cutar sankarar lymphoblastic mai tsanani (ALL), cutar sankarar bargo ta myeloblastic (AML), neuroblastoma, sarcomas, nono, ovarian, mafitsara, thyroid, ciki da yawa. sauran ciwon daji. Doxorubicin yana iya kashe mai girma da sauri ciwon daji Kwayoyin ta hanyar haifar da lalacewar DNA da yawa da kuma ƙara yawan damuwa na oxidative wanda kuma ke haifar da mutuwar tantanin halitta. Duk da haka, wannan tasirin Doxorubicin yana haifar da mummunar lalacewa ga sel masu lafiya, tare da cardiotoxicity a matsayin daya daga cikin mafi girman sakamako masu illa da ke da yiwuwar rashin ciwon zuciya mai tsanani, wanda zai iya faruwa ko dai a lokacin jiyya ko watanni ko shekaru bayan maganin. . Haɓaka yuwuwar cututtukan zuciya, kamar yadda aka tantance ta alamun alamu da alamu daban-daban gami da raguwar ayyukan zuciya ko canjin matakan mahimman alamomin enzyme na zuciya, yana ƙaruwa tare da haɓaka jimlar adadin Doxorubicin.
Wannan rikice-rikicen kawar da cutar kansa tare da ma'amala mai tsanani kuma wani lokacin mawuyacin tasiri-rikicewa ce mai ci gaba a cikin yankin cutar kansa. Saboda haka, akwai ci gaba da ƙoƙari don neman hanyoyin da za su iya taimakawa wajen ragewa ko kare mai haƙuri daga mummunar illa. Masu bincike sunyi nazarin tasirin wasu tsire-tsire masu tsire-tsire da aka samo a yayin da aka ɗauke su tare da Doxorubicin akan ƙarshen cututtukan zuciya a cikin ƙwayoyin ƙwayoyin cuta da nau'ikan cututtukan dabbobi, kwatankwacin waɗanda aka yi amfani da su a cikin tsarin haɓaka ƙwayoyi don ƙwayoyi masu yarda. Suchaya daga cikin irin waɗannan tsire-tsire da aka samo Silymarin mai aiki daga tsiron Milk thistle an gwada shi a cikin binciken gwaji da yawa kuma ya nuna tasirin kariya a cikin zuciya.
Milk Thistle da Silymarin mai aiki
Milk ƙaya tsire-tsire ne wanda aka yi amfani dashi tsawon ƙarni don maganin ciwon hanta da ɓarna a Turai. Hakanan ana samun shi azaman abincin abincin. Milist thistle ya samo sunansa daga ruwan madarar da ake fitarwa lokacin da ganyen ya karye. Mabudin sinadarin bioactive na tsaba Milk Thistle sun hada da Silibinin (silybin), Isosilybin, Silychristin da Silydianin wanda aka fi sani da Silymarin.
Abincin da Zai Ci Bayan Bayanan Ciwon Cutar Kansa!
Babu cutar kansa guda biyu iri daya. Wuce ka'idojin abinci mai gina jiki na kowa don kowa kuma yanke hukunci na musamman game da abinci da kari tare da ƙarfin gwiwa.
Amfani da Milk Thistle mai aiki Silymarin don Doxorubicin-haifar da Cardiotoxicity a cutar sankarar bargo
Silymarin an nuna ta gwaji don samun tasirin kwayar cutar lokacin da aka ba ta tare da Doxorubicin (rage ƙwayar cutar ta Doxorubicin da ke haifar da cutar). Silymarin zai iya rage danniya, kamar yadda yake haifar da bugun zuciya. Yana da antioxidant kuma yana iya rage lalacewa ga membranes da sunadarai ta jinsin mai amsawa, waɗanda aka kirkiresu a matsayin ɓangare na aikin Doxorubicin na aiki, ta hana ƙarancin kayan aikin antioxidant na ƙwayoyin lafiya (Roskovic A et al, Molecules 2011) .
Nazarin Clinical akan Silymarin Amfani & Doxorubicin-haifar da Cardiotoxicity
Wani binciken asibiti daga Jami'ar Tanta a Misira ya gwada fa'idodi / kariya daga cutar Silymarin daga Milk Thistle a cikin yara masu fama da cutar sankarar bargo ta lymphoblastic (ALL), waɗanda ake bi da su tare da Doxorubicin (Hagag AA et al, Ciwon Cutar Cutar Cutar. 2019). A cikin wannan binciken akan yara 80 tare da ALL, 40 daga cikinsu an yi musu magani tare da Doxorubicin tare da Silymarin a 420 mg / day (Rukunin I - gwaji) kuma sauran 40 an yi maganin su ne tare da Doxorubicin ba tare da Silymarin ba (Rukunin 2 - placebo). Kimantawar aikin zuciya a cikin waɗannan yara an yi su ne ta hanyar matakan echo-Doppler na al'ada na aikin systolic da diastolic. Sun gano cewa a cikin rukunin Silymarin, akwai 'raguwar farkon Doxorubicin wanda ya haifar da rikicewar aikin hagu na hagu na zuciya (cardiotoxicity)' akan ƙungiyar placebo.
Kammalawa
Binciken ya nuna cewa Milk Thistle mai aiki Silymarin na iya samun fa'idodi a cikin marasa lafiya na ciwon daji kamar ragewar Doxorubicin-induced Cardiotoxicity a cikin Yara masu fama da cutar sankarar bargo. Wannan binciken na asibiti, ko da yake tare da ƙananan yara na cutar sankarar bargo, yana ba da wasu tabbaci game da tasirin cututtukan zuciya (amfanin) Milk thistle mai aiki Silymarin kamar yadda aka gani a cikin samfurin cututtuka na gwaji. Duk da tasiri mai amfani na abubuwan kariyar halitta bisa ga gwaji da ƙananan nazarin asibiti, masu ciwon daji dole ne suyi taka tsantsan wajen ɗaukar waɗannan kari tare da su. ciwon daji jiyya. Waɗannan abubuwan kari na halitta ba su wuce ta gwaji mai yawa da amincewar ka'idoji ba kuma ba a nufin magani, hanawa ko warkar da cutar ba. Hakanan, akwai yuwuwar kariyar shuka da hulɗar magunguna waɗanda zasu iya tsoma baki tare da jiyya kuma suna iya zama haɗari a wasu lokuta. Don haka, masu ciwon daji yakamata su tuntuɓi likitan su koyaushe kafin amfani da kowane kari na halitta.
Abincin da kuke ci kuma wanne kari kuke ɗauka shine yanke shawara. Ya kamata shawararku ta haɗa da la'akari da maye gurbi na ciwon daji, wanda cutar kansa, jiyya da ci gaba da gudana, duk wani rashin lafiyan, bayanin salon rayuwa, nauyi, tsayi da halaye.
Tsarin abinci mai gina jiki don cutar kansa daga addon baya dogara ne akan binciken intanet. Yana sarrafa muku yanke shawara ta atomatik dangane da kimiyyar kwayoyin da masana kimiyya da injiniyoyin software suka aiwatar. Ba tare da la’akari da ko kuna kula da fahimtar hanyoyin hanyoyin kwayoyin halittar biochemical ko a'a - don shirin abinci mai gina jiki don cutar kansa wanda ake buƙatar fahimta.
Fara NOW tare da shirin abinci mai gina jiki ta hanyar amsa tambayoyi kan sunan cutar kansa, maye gurbi, jiyya mai gudana da kari, duk wani rashin lafiyan, halaye, salon rayuwa, ƙungiyar shekaru da jinsi.
Keɓaɓɓen Abinci don Ciwon daji!
Ciwon daji yana canzawa da lokaci. Keɓancewa da canza abincin ku dangane da alamun cutar kansa, jiyya, salon rayuwa, abubuwan da ake so abinci, alerji da sauran dalilai.
Marasa lafiya masu cutar kansa sau da yawa dole su magance daban-daban illar illa na chemotherapy wanda ke shafar ingancin rayuwarsu da kuma neman wasu hanyoyin magance cutar kansa. Shan da madaidaicin abinci mai gina jiki da kari bisa la'akari na kimiyya (gujewa zato da zabin bazata) shine mafi kyawun maganin halitta don cutar kansa da cututtukan da suka shafi jiyya.