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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Foods for Choroid Plexus Carcinoma/Tumors!

Aug 4, 2023

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Introduction

Foods for Choroid Plexus Tumors should be personalized for each individual and also must adapt when cancer treatment or tumor genetic change. The personalization and adaptation must consider all the active ingredients or bioactives contained in different foods with respect to cancer tissue biology, genetics, treatments, lifestyle conditions and diet preferences. Hence while nutrition is one of the very important decisions for a cancer patient and individual at risk of cancer to make – how to choose foods to eat is not an easy task.



For Choroid Plexus Tumors does it matter what vegetables, fruits, nuts, seeds one eats?

A very common nutrition question asked by cancer patients and individuals at-genetic risk of cancer is – for cancers like Choroid Plexus Tumors does it matter what foods I eat and which I do not? Or if I follow a plant-based diet is that enough for cancer like Choroid Plexus Tumors?

For example does it matter if vegetable Parsnip is consumed more compared to Arrowhead? Does it make any difference if fruit Babassu Palm is preferred over Pomegranate? Also if similar choices are made for nuts/seeds like Butternut over Pili Nut and for pulses like Moth Bean over Catjang Pea. And if what I eat matters – then how does one identify foods which are recommended for Choroid Plexus Tumors and is it the same answer for everyone with the same diagnosis or genetic risk?

Yes! Foods you eat matters for Choroid Plexus Tumors!

Food recommendations may not be the same for everyone and can be different even for the same diagnosis and genetic risk.

All cancers like Choroid Plexus Tumors can be characterized by a unique set of biochemical pathways - the signature pathways of Choroid Plexus Tumors. Biochemical pathways like DNA Repair, Hypoxia, Apoptosis, MAPK Signaling are part of the signature definition of Choroid Plexus Tumors.

All foods (vegetables, fruits, nuts, seeds, pulses, oils etc.) and nutritional supplements are made up of more than one active molecular ingredient or bio-actives in different proportions and quantities. Each active ingredient has a unique mechanism of action – which can be activation or inhibition of different biochemical pathways. Simply stated foods and supplements which are recommended are those which do not cause an increase of molecular drivers of cancer but reduce them. Else those foods should not be recommended. Foods contain multiple active ingredients – hence when evaluating foods and supplements you need to consider the impact of all active ingredients cumulatively rather than individually.

For example Babassu Palm contains active ingredients Curcumin, Apigenin, Allicin, Daidzein, Lupeol. And Pomegranate contains active ingredients Curcumin, Betulinic Acid, Apigenin, Oleic Acid, Ellagic Acid and possibly others.

A common mistake made when deciding and choosing foods to eat for Choroid Plexus Tumors – is to evaluate only selected active ingredients contained in foods and ignore the rest. Because different active ingredients contained in foods may have opposing effects on cancer drivers – you cannot cherry pick active ingredients in foods and supplements for making a nutrition decision for Choroid Plexus Tumors.

YES – FOOD CHOICES MATTER FOR CANCER. NUTRITION DECISIONS MUST CONSIDER ALL ACTIVE INGREDIENTS OF FOODS.

Skills Needed for Nutrition Personalization for Choroid Plexus Tumors?

Personalized nutrition for cancers like Choroid Plexus Tumors consists of recommended foods / supplements; not recommended foods / supplements with example recipes which prioritize use of recommended foods. An example of personalized nutrition can be seen at this link.

Deciding which foods are recommended or not is extremely complicated, requiring expertise in Choroid Plexus Tumors biology, food science, genetics, biochemistry along with good understanding of how cancer treatments work and associated vulnerabilities by which the treatments could stop being effective.

MINIMUM KNOWLEDGE EXPERTISE NEEDED FOR NUTRITION PERSONALIZATION FOR CANCER ARE: CANCER BIOLOGY, FOOD SCIENCE, CANCER TREATMENTS AND GENETICS.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Characteristics of cancers like Choroid Plexus Tumors

All cancers like Choroid Plexus Tumors can be characterized by a unique set of biochemical pathways – the signature pathways of Choroid Plexus Tumors. Biochemical pathways like DNA Repair, Hypoxia, Apoptosis, MAPK Signaling are part of the signature definition of Choroid Plexus Tumors. Each individual’s cancer genetics can be different and hence their specific cancer signature could be unique.

The treatments which are effective for Choroid Plexus Tumors need to be cognizant of the associated signature biochemical pathways for each cancer patient and individual at genetic risk. Therefore different treatments with different mechanisms of actions are effective for different patients. Similarly and for the same reasons foods and supplements need to be personalized for each individual. Hence some foods and supplements are recommended for Choroid Plexus Tumors when taking cancer treatment Etoposide, and some foods and supplements are not recommended.

Sources like cBioPortal and many others provide population representative patient anonymized data from clinical trials for all cancer indications. This data consists of clinical trial study details like sample size / number of patients, age groups, gender, ethnicity, treatments, tumor site and any genetic mutations.

TERT, TP53, CIITA, POLQ and IDH1 are the top ranked reported genes for Choroid Plexus Tumors. TERT is reported in 25.0 % of the representative patients across all clinical trials. And TP53 is reported in 22.2 %. The combined population patient data cover ages from to . 0.0 % of the patient data are identified as men. The Choroid Plexus Tumors biology along with reported genetics together define the population represented signature biochemical pathways for this cancer. If the individual cancer tumor genetics or genes contributing to the risk are also known then that should also be used for nutrition personalization.

NUTRITION CHOICES SHOULD MATCH WITH EACH INDIVIDUAL’S CANCER SIGNATURE.

Foods for Choroid Plexus Tumors!

Food and Supplements for Choroid Plexus Tumors

For Cancer Patients

Cancer patients on treatment or on palliative care need to make decisions on food and supplements – for the needed dietary calories, for managing any treatment side effects and also for improved cancer management. All plant-based foods are not equal and choosing and prioritizing foods which are personalized and customized to ongoing cancer treatment is important and complicated. Here are some examples providing guidelines for making nutrition decisions.

Choose Vegetable PARSNIP or ARROWHEAD?

Vegetable Parsnip contains many active ingredients or bioactives such as Curcumin, Oleic Acid, Allicin, Daidzein, Lupeol. These active ingredients manipulate various biochemical pathways like WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling, Hypoxia and MYC Signaling and others. Parsnip is recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide. This is because Parsnip modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Etoposide.

Some of the active ingredients or bioactives in vegetable Arrowhead are Curcumin, Apigenin, Allicin, Caffeine, Daidzein. These active ingredients manipulate various biochemical pathways like WNT Beta Catenin Signaling and DNA Repair and others. Arrowhead is not recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

VEGETABLE PARSNIP IS RECOMMENDED OVER ARROWHEAD FOR Choroid Plexus Tumors AND TREATMENT Etoposide.

Choose Fruit POMEGRANATE or BABASSU PALM?

Fruit Pomegranate contains many active ingredients or bioactives such as Curcumin, Betulinic Acid, Apigenin, Oleic Acid, Ellagic Acid. These active ingredients manipulate various biochemical pathways like WNT Beta Catenin Signaling, Hedgehog Signaling, DNA Repair and MYC Signaling and others. Pomegranate is recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide. This is because Pomegranate modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Etoposide.

Some of the active ingredients or bioactives in fruit Babassu Palm are Curcumin, Apigenin, Allicin, Daidzein, Lupeol. These active ingredients manipulate various biochemical pathways like DNA Repair and others. Babassu Palm is not recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

FRUIT POMEGRANATE IS RECOMMENDED OVER BABASSU PALM FOR Choroid Plexus Tumors AND TREATMENT Etoposide.

Choose Nut BUTTERNUT or PILI NUT?

Butternut contains many active ingredients or bioactives such as Curcumin, Apigenin, Oleic Acid, Allicin, Caffeine. These active ingredients manipulate various biochemical pathways like WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling and Hypoxia and others. Butternut is recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide. This is because Butternut modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Etoposide.

Some of the active ingredients or bioactives in Pili Nut are Curcumin, Apigenin, Allicin, Caffeine, Daidzein. These active ingredients manipulate various biochemical pathways like WNT Beta Catenin Signaling and DNA Repair and others. Pili Nut is not recommended for Choroid Plexus Tumors when ongoing cancer treatment is Etoposide because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

BUTTERNUT IS RECOMMENDED OVER PILI NUT FOR Choroid Plexus Tumors AND TREATMENT Etoposide.

For Individuals with Genetic Risk of Cancer

The question asked by individuals who have genetic risk of Choroid Plexus Tumors or familial history is “What Should I Eat Differently from Before?” and how they should choose foods and supplements to manage risks of the disease. Since for cancer risk there is nothing actionable in terms of treatment – decisions of foods and supplements become important and one of the very few actionable things which can be done. All plant-based foods are not equal and based on identified genetics and pathway signature – the choices of food and supplements should be personalized.

Choose Vegetable GIANT BUTTERBUR or BLACK CABBAGE?

Vegetable Giant Butterbur contains many active ingredients or bioactives such as Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like JAK-STAT Signaling, Angiogenesis, Cell Cycle and PI3K-AKT-MTOR Signaling and others. Giant Butterbur is recommended for risk of Choroid Plexus Tumors when associated genetic risk is CIITA. This is because Giant Butterbur increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in vegetable Black Cabbage are Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like Stem Cell Signaling and Oncogenic Cancer Epigenetics and others. Black Cabbage is not recommended when risk of Choroid Plexus Tumors when associated genetic risk is CIITA because it increases the signature pathways of it.

VEGETABLE GIANT BUTTERBUR IS RECOMMENDED OVER BLACK CABBAGE FOR CIITA GENETIC RISK OF CANCER.

Choose Fruit NANCE or PUMMELO?

Fruit Nance contains many active ingredients or bioactives such as Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like Cell Cycle, PI3K-AKT-MTOR Signaling and Hypoxia and others. Nance is recommended for risk of Choroid Plexus Tumors when associated genetic risk is CIITA. This is because Nance increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in fruit Pummelo are Apigenin, Curcumin, Quercetin, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like Stem Cell Signaling and Cell Cycle Checkpoints and others. Pummelo is not recommended when risk of Choroid Plexus Tumors when associated genetic risk is CIITA because it increases the signature pathways of it.

FRUIT NANCE IS RECOMMENDED OVER PUMMELO FOR CIITA GENETIC RISK OF CANCER.

Choose Nut COMMON WALNUT or EUROPEAN CHESTNUT?

Common Walnut contains many active ingredients or bioactives such as Curcumin, Quercetin, Formononetin, Lupeol, Ellagic Acid. These active ingredients manipulate various biochemical pathways like Angiogenesis, Cell Cycle, JAK-STAT Signaling and P53 Signaling and others. Common Walnut is recommended for risk of Choroid Plexus Tumors when associated genetic risk is CIITA. This is because Common Walnut increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in European Chestnut are Apigenin, Curcumin, Quercetin, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like Stem Cell Signaling and others. European Chestnut is not recommended when risk of Choroid Plexus Tumors when associated genetic risk is CIITA because it increases the signature pathways of it.

COMMON WALNUT IS RECOMMENDED OVER EUROPEAN CHESTNUT FOR CIITA GENETIC RISK OF CANCER.


In Conclusion

Foods and Supplements chosen are important decisions for cancers like Choroid Plexus Tumors. Choroid Plexus Tumors patients and individuals with genetic-risk always have this question: “What foods and nutritional supplements are recommended for me and which are not?” There is a common belief which is a misconception that all plant-based foods could be beneficial or not but would not be harmful. Certain foods and supplements can interfere with cancer treatments or promote molecular pathway drivers of cancer.

There are different types of cancer indications like Choroid Plexus Tumors, each with different tumor genetics with further genomic variations across each individual. Further every cancer treatment and chemotherapy has a unique mechanism of action. Each food like Parsnip contains various bioactives in different quantities, which have an impact on different and distinct sets of biochemical pathways. The definition of personalized nutrition is individualized food recommendations for the cancer indication, treatments, genetics, lifestyle and other factors. Nutrition personalization decisions for cancer require knowledge of cancer biology, food science and an understanding of different chemotherapy treatments. Finally when there are treatment changes or new genomics is identified – the nutrition personalization needs re-evaluation.

The addon nutrition personalization solution makes the decision making easy and removes all the guesswork in answering the question, “What foods should I choose or not choose for Choroid Plexus Tumors?”. The addon multi-disciplinary team includes cancer physicians, clinical scientists, software engineers and data scientists.


Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.

References

Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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