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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Foods for Hemangiopericytoma!

Jul 18, 2023

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Introduction

Foods for Hemangiopericytoma should be personalized for each individual and also must adapt when cancer treatment or tumor genetic change. The personalization and adaptation must consider all the active ingredients or bioactives contained in different foods with respect to cancer tissue biology, genetics, treatments, lifestyle conditions and diet preferences. Hence while nutrition is one of the very important decisions for a cancer patient and individual at risk of cancer to make – how to choose foods to eat is not an easy task.

Hemangiopericytoma, also known as solitary fibrous tumor, is a rare type of cancer that arises from the cells surrounding blood vessels called pericytes. Accurate medical coding using the appropriate ICD-10 code is important for documentation. Radiology plays a crucial role in the evaluation and diagnosis of hemangiopericytoma, providing valuable insights into its characteristics and location. Pathology outlines offer valuable information about the distinctive features of hemangiopericytoma cells. Hemangiopericytoma can affect various parts of the body, including the brain, liver, and eye. Treatment for hemangiopericytoma generally involves surgery, radiation therapy, and sometimes chemotherapy, depending on the specific case. Survival rates and prognosis for hemangiopericytoma vary depending on factors such as tumor stage and location. Raising awareness and adhering to treatment guidelines are essential for optimizing outcomes in patients with hemangiopericytoma. By seeking appropriate veterinary care for hemangiopericytoma in dogs, owners can improve their pet’s chances of successful outcomes and enhance their quality of life.



For Hemangiopericytoma does it matter what vegetables, fruits, nuts, seeds one eats?

A very common nutrition question asked by cancer patients and individuals at-genetic risk of cancer is – for cancers like Hemangiopericytoma does it matter what foods I eat and which I do not? Or if I follow a plant-based diet is that enough for cancer like Hemangiopericytoma?

For example does it matter if vegetable Orange Bell Pepper is consumed more compared to Daikon Radish? Does it make any difference if fruit Pummelo is preferred over Java Plum? Also if similar choices are made for nuts/seeds like Chia over Cashew Nut and for pulses like White Lupine over Yardlong Bean. And if what I eat matters – then how does one identify foods which are recommended for Hemangiopericytoma and is it the same answer for everyone with the same diagnosis or genetic risk?

Yes! Foods you eat matters for Hemangiopericytoma!

Food recommendations may not be the same for everyone and can be different even for the same diagnosis and genetic risk.

All cancers like Hemangiopericytoma can be characterized by a unique set of biochemical pathways - the signature pathways of Hemangiopericytoma. Biochemical pathways like PI3K-AKT-MTOR Signaling, TGFB Signaling, Apoptosis, Cell Cycle Checkpoints are part of the signature definition of Hemangiopericytoma.

All foods (vegetables, fruits, nuts, seeds, pulses, oils etc.) and nutritional supplements are made up of more than one active molecular ingredient or bio-actives in different proportions and quantities. Each active ingredient has a unique mechanism of action – which can be activation or inhibition of different biochemical pathways. Simply stated foods and supplements which are recommended are those which do not cause an increase of molecular drivers of cancer but reduce them. Else those foods should not be recommended. Foods contain multiple active ingredients – hence when evaluating foods and supplements you need to consider the impact of all active ingredients cumulatively rather than individually.

For example Pummelo contains active ingredients Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. And Java Plum contains active ingredients Apigenin, Curcumin, Daidzein, Lycopene, Lupeol and possibly others.

A common mistake made when deciding and choosing foods to eat for Hemangiopericytoma – is to evaluate only selected active ingredients contained in foods and ignore the rest. Because different active ingredients contained in foods may have opposing effects on cancer drivers – you cannot cherry pick active ingredients in foods and supplements for making a nutrition decision for Hemangiopericytoma.

YES – FOOD CHOICES MATTER FOR CANCER. NUTRITION DECISIONS MUST CONSIDER ALL ACTIVE INGREDIENTS OF FOODS.

Skills Needed for Nutrition Personalization for Hemangiopericytoma?

Personalized nutrition for cancers like Hemangiopericytoma consists of recommended foods / supplements; not recommended foods / supplements with example recipes which prioritize use of recommended foods. An example of personalized nutrition can be seen at this link.

Deciding which foods are recommended or not is extremely complicated, requiring expertise in Hemangiopericytoma biology, food science, genetics, biochemistry along with good understanding of how cancer treatments work and associated vulnerabilities by which the treatments could stop being effective.

MINIMUM KNOWLEDGE EXPERTISE NEEDED FOR NUTRITION PERSONALIZATION FOR CANCER ARE: CANCER BIOLOGY, FOOD SCIENCE, CANCER TREATMENTS AND GENETICS.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Characteristics of cancers like Hemangiopericytoma

All cancers like Hemangiopericytoma can be characterized by a unique set of biochemical pathways – the signature pathways of Hemangiopericytoma. Biochemical pathways like PI3K-AKT-MTOR Signaling, TGFB Signaling, Apoptosis, Cell Cycle Checkpoints are part of the signature definition of Hemangiopericytoma. Each individual’s cancer genetics can be different and hence their specific cancer signature could be unique.

The treatments which are effective for Hemangiopericytoma need to be cognizant of the associated signature biochemical pathways for each cancer patient and individual at genetic risk. Therefore different treatments with different mechanisms of actions are effective for different patients. Similarly and for the same reasons foods and supplements need to be personalized for each individual. Hence some foods and supplements are recommended for Hemangiopericytoma when taking cancer treatment Topotecan, and some foods and supplements are not recommended.

Sources like cBioPortal and many others provide population representative patient anonymized data from clinical trials for all cancer indications. This data consists of clinical trial study details like sample size / number of patients, age groups, gender, ethnicity, treatments, tumor site and any genetic mutations.

TERT, TP53, BCOR, BTK and KDM5C are the top ranked reported genes for Hemangiopericytoma. TERT is reported in 46.2 % of the representative patients across all clinical trials. And TP53 is reported in 30.8 %. The combined population patient data cover ages from to . 48.7 % of the patient data are identified as men. The Hemangiopericytoma biology along with reported genetics together define the population represented signature biochemical pathways for this cancer. If the individual cancer tumor genetics or genes contributing to the risk are also known then that should also be used for nutrition personalization.

NUTRITION CHOICES SHOULD MATCH WITH EACH INDIVIDUAL’S CANCER SIGNATURE.

Foods for Hemangiopericytoma!

Food and Supplements for Hemangiopericytoma

For Cancer Patients

Cancer patients on treatment or on palliative care need to make decisions on food and supplements – for the needed dietary calories, for managing any treatment side effects and also for improved cancer management. All plant-based foods are not equal and choosing and prioritizing foods which are personalized and customized to ongoing cancer treatment is important and complicated. Here are some examples providing guidelines for making nutrition decisions.

Choose Vegetable ORANGE BELL PEPPER or DAIKON RADISH

Vegetable Orange Bell Pepper contains many active ingredients or bioactives such as Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. These active ingredients manipulate various biochemical pathways like NFKB Signaling, MYC Signaling, TGFB Signaling and PI3K-AKT-MTOR Signaling and others. Orange Bell Pepper is recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan. This is because Orange Bell Pepper modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Topotecan.

Some of the active ingredients or bioactives in vegetable Daikon Radish are Apigenin, Curcumin, Daidzein, Lupeol, Formononetin. These active ingredients manipulate various biochemical pathways like TGFB Signaling and NFKB Signaling and others. Daikon Radish is not recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

VEGETABLE ORANGE BELL PEPPER IS RECOMMENDED OVER DAIKON RADISH FOR Hemangiopericytoma AND TREATMENT Topotecan.

Choose Fruit JAVA PLUM or PUMMELO

Fruit Java Plum contains many active ingredients or bioactives such as Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. These active ingredients manipulate various biochemical pathways like Apoptosis, MYC Signaling, NFKB Signaling and PI3K-AKT-MTOR Signaling and others. Java Plum is recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan. This is because Java Plum modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Topotecan.

Some of the active ingredients or bioactives in fruit Pummelo are Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints and NFKB Signaling and others. Pummelo is not recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

FRUIT JAVA PLUM IS RECOMMENDED OVER PUMMELO FOR Hemangiopericytoma AND TREATMENT Topotecan.

Choose Nut CHIA or CASHEW NUT

Chia contains many active ingredients or bioactives such as Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints, TGFB Signaling, NFKB Signaling and MYC Signaling and others. Chia is recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan. This is because Chia modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Topotecan.

Some of the active ingredients or bioactives in Cashew Nut are Curcumin, Daidzein, Lupeol, Formononetin, Phloretin. These active ingredients manipulate various biochemical pathways like NFKB Signaling and PI3K-AKT-MTOR Signaling and others. Cashew Nut is not recommended for Hemangiopericytoma when ongoing cancer treatment is Topotecan because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

CHIA IS RECOMMENDED OVER CASHEW NUT FOR Hemangiopericytoma AND TREATMENT Topotecan.

For Individuals with Genetic Risk of Cancer

The question asked by individuals who have genetic risk of Hemangiopericytoma or familial history is “What Should I Eat Differently from Before?” and how they should choose foods and supplements to manage risks of the disease. Since for cancer risk there is nothing actionable in terms of treatment – decisions of foods and supplements become important and one of the very few actionable things which can be done. All plant-based foods are not equal and based on identified genetics and pathway signature – the choices of food and supplements should be personalized.

Choose Vegetable BURDOCK or BLACK CABBAGE

Vegetable Burdock contains many active ingredients or bioactives such as Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like B Cell Receptor Signaling, MYC Signaling, NFKB Signaling and PI3K-AKT-MTOR Signaling and others. Burdock is recommended for risk of Hemangiopericytoma when associated genetic risk is BCOR. This is because Burdock increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in vegetable Black Cabbage are Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like NFKB Signaling and Oncogenic Cancer Epigenetics and others. Black Cabbage is not recommended when risk of Hemangiopericytoma when associated genetic risk is BCOR because it increases the signature pathways of it.

VEGETABLE BURDOCK IS RECOMMENDED OVER BLACK CABBAGE FOR BCOR GENETIC RISK OF CANCER.

Choose Fruit HIGHBUSH BLUEBERRY or ACEROLA

Fruit Highbush Blueberry contains many active ingredients or bioactives such as Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints, Phospholipase Signaling, NFKB Signaling and MYC Signaling and others. Highbush Blueberry is recommended for risk of Hemangiopericytoma when associated genetic risk is BCOR. This is because Highbush Blueberry increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in fruit Acerola are Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like NFKB Signaling and Oncogenic Cancer Epigenetics and others. Acerola is not recommended when risk of Hemangiopericytoma when associated genetic risk is BCOR because it increases the signature pathways of it.

FRUIT HIGHBUSH BLUEBERRY IS RECOMMENDED OVER ACEROLA FOR BCOR GENETIC RISK OF CANCER.

Choose Nut BUTTERNUT or EUROPEAN CHESTNUT

Butternut contains many active ingredients or bioactives such as Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints, Phospholipase Signaling, NFKB Signaling and MYC Signaling and others. Butternut is recommended for risk of Hemangiopericytoma when associated genetic risk is BCOR. This is because Butternut increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in European Chestnut are Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints, Oncogenic Cancer Epigenetics and Stem Cell Signaling and others. European Chestnut is not recommended when risk of Hemangiopericytoma when associated genetic risk is BCOR because it increases the signature pathways of it.

BUTTERNUT IS RECOMMENDED OVER EUROPEAN CHESTNUT FOR BCOR GENETIC RISK OF CANCER.


In Conclusion

Foods and Supplements chosen are important decisions for cancers like Hemangiopericytoma. Hemangiopericytoma patients and individuals with genetic-risk always have this question: “What foods and nutritional supplements are recommended for me and which are not?” There is a common belief which is a misconception that all plant-based foods could be beneficial or not but would not be harmful. Certain foods and supplements can interfere with cancer treatments or promote molecular pathway drivers of cancer.

There are different types of cancer indications like Hemangiopericytoma, each with different tumor genetics with further genomic variations across each individual. Further every cancer treatment and chemotherapy has a unique mechanism of action. Each food like Orange Bell Pepper contains various bioactives in different quantities, which have an impact on different and distinct sets of biochemical pathways. The definition of personalized nutrition is individualized food recommendations for the cancer indication, treatments, genetics, lifestyle and other factors. Nutrition personalization decisions for cancer require knowledge of cancer biology, food science and an understanding of different chemotherapy treatments. Finally when there are treatment changes or new genomics is identified – the nutrition personalization needs re-evaluation.

The addon nutrition personalization solution makes the decision making easy and removes all the guesswork in answering the question, “What foods should I choose or not choose for Hemangiopericytoma?”. The addon multi-disciplinary team includes cancer physicians, clinical scientists, software engineers and data scientists.


Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.

References

Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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