No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Tongue Cancer needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Bamboo and Bottle Gourd should be eaten when undergoing Cisplatin treatment for Tongue Cancer. On the same lines, avoid foods like Kale and Parsnip with treatment of Cisplatin for Tongue Cancer.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Tongue Cancer.
What is Tongue Cancer?
Tongue Cancer is a type of cancer that develops from the cells of the tongue. The incidence rate of this cancer is 3.6 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 60 years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.
Tongue Cancer has prevalence of certain genetic changes. Some of the genes such as TP53, TERT, CDKN2A, and NOTCH1 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Tongue Cancer can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Tongue Cancer. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Tongue Cancer genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Tongue Cancer nutrition may have to be redesigned.
Why Eating Right Matters for Tongue Cancer?
In Tongue Cancer, activation or inhibition of some of the biochemical pathways including Adherens Junction, MAPK Signaling, MYC Signaling, Angiogenesis, Epithelial To Mesenchymal Transition, RUNX Signaling, AXON Guidance, WNT Beta Catenin Signaling, Cell Cycle Checkpoints, Focal Adhesion, DNA Repair, NFKB Signaling, P53 Signaling, Oxidative Stress, Cell Cycle, NOTCH Signaling and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Tongue Cancer, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Cisplatin treatment for Tongue Cancer
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Tongue Cancer considering only one specific treatment – Cisplatin.
Foods to Avoid with Cisplatin treatment
Kale : Kale contains active ingredients such as Folic Acid, Linolenic Acid, Brassinin and others. Folic Acid interferes with the impact of Cisplatin in Tongue Cancer by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Kale with Cisplatin treatment for Tongue Cancer.
Parsnip : Parsnip contains active ingredients such as Linoleic Acid, Psoralen, Myristicin and others. Linoleic Acid interferes with the impact of Cisplatin in Tongue Cancer by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Parsnip with Cisplatin treatment for Tongue Cancer.
Foods to Eat with Cisplatin treatment
Bamboo : Bamboo contains active ingredients like Beta-sitosterol, Linolenic Acid and Citric Acid. Intake of Beta-sitosterol along with Cisplatin treatment for Tongue Cancer causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bamboo hence should be eaten with Cisplatin treatment for Tongue Cancer. (Zhang-Qi Cao et al, Front Pharmacol., 2019; Erminia Massarelli et al, Cancer., 2005; Dong-Jun Peng et al, Biochem Biophys Res Commun., 2010)
Bottle Gourd : Bottle Gourd contains active ingredients like Vitamin C, Linolenic Acid and Retinol. Intake of Vitamin C along with Cisplatin treatment for Tongue Cancer causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bottle Gourd hence should be eaten with Cisplatin treatment for Tongue Cancer. (Sushmita Mustafi et al, Theranostics., 2021; Erminia Massarelli et al, Cancer., 2005; Dong-Jun Peng et al, Biochem Biophys Res Commun., 2010)
Should I take this Nutritional Supplement with Cisplatin treatment?
Curcumin : Curcumin has no known reported CYP (drug metabolizing enzyme) interactions with Cisplatin treatment. Curcumin supports the Cisplatin treatment for Tongue Cancer by decreasing the biochemical pathways/processes called Cell Survival, C-type Lectin Receptor Signaling, WNT Beta Catenin Signaling, Epithelial to Mesenchymal Transition, MAPK Signaling, DNA Repair, JAK-STAT Signaling, Cell Cycle, MYC Signaling, NFKB Signaling and PI3K-AKT-MTOR Signaling and increasing pathways like Cell Cycle Checkpoints, Oxidative Stress, P53 Signaling, RUNX Signaling and Vitamin D Signaling.
What are the Symptoms of Tongue Cancer?
In the initial stages, most cancers including Tongue Cancer may not cause any signs or symptoms. However, as the disease progresses, Tongue Cancer may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Tongue Cancer.
- Persistent red or white patch on the tongue
- Persistent tongue ulcer
- Persistent lump on the tongue
- Persistent sore throat
- Bleeding from the tongue
- Swallowing difficulties
- Numbness in the mouth
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Tongue Cancer.
What are the Treatment Options for Tongue Cancer?
The treatment for Tongue Cancer may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back.
The treatment options for Tongue Cancer include:
- Targeted Therapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Tongue Cancer.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Tongue Cancer.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.