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What should I Eat?

is the most common question asked by cancer patients.
Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

is the most common question asked by cancer patients. Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

Get your personalized nutrition plan for cancer at 

Get your personalized nutrition plan for cancer at

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Which 3 Foods to Avoid for Paranasal Sinus and Nasal Cavity Cancer?

Apr 22, 2021

Home » Blogs » Which 3 Foods to Avoid for Paranasal Sinus and Nasal Cavity Cancer?

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Paranasal Sinus and Nasal Cavity Cancer needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Aloe Vera and Avocado should be eaten when undergoing Cisplatin treatment for Paranasal Sinus and Nasal Cavity Cancer. On the other hand, for this Cancer, Allspice and Almond should be eaten with treatment of Fluorouracil. On the same lines, foods like Amaranth and Beetroot should be avoided with treatment of Cisplatin for this Cancer. If the treatment is Fluorouracil, then avoid Green Bean and Kohlrabi.

Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Cisplatin and Fluorouracil treatments and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Paranasal Sinus and Nasal Cavity Cancer.



What is Paranasal Sinus and Nasal Cavity Cancer?

Paranasal Sinus and Nasal Cavity Cancer is a rare cancer that develops in the lining of the space behind the nose (nasal cavity) or the nearby air cavities (paranasal sinuses). It may also spread to the lymph nodes. The incidence rate of this cancer is only 0.44 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 60 years of age, however, it can occur in people of any age. It is more commonly found in black population as compared to white population.

Paranasal Sinus and Nasal Cavity Cancer  - Symptoms, treatment, diet, foods

This Cancer have prevalence of certain genetic changes. Some of the genes such as TP53, ERCC1, TRIM37, and POLH are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in this Cancer can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for this Cancer. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Paranasal Sinus and Nasal Cavity Cancer genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer may have to be redesigned.

Why Eating Right Matters for Paranasal Sinus and Nasal Cavity Cancer?

In this Cancer, activation or inhibition of some of the biochemical pathways including Vitamin D Signaling, NFKB Signaling, P53 Signaling, Cell Cycle, Oxidative Stress, PI3K-AKT-MTOR Signaling, Angiogenesis, DNA Repair, MYC Signaling and MAPK Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Paranasal Sinus and Nasal Cavity Cancer, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Paranasal Sinus and Nasal Cavity Cancer - Foods to take and Avoid

Example Foods to “Not Eat” and Eat with Cisplatin treatment for Paranasal Sinus and Nasal Cavity Cancer

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Paranasal Sinus and Nasal Cavity Cancer considering only one specific treatment.

Foods to Avoid

Amaranth : Amaranth contains active ingredients such as Citric Acid, Vitamin C, Isoquercitrin and others. Citric Acid interferes with the impact of Cisplatin in Paranasal Sinus and Nasal Cavity Cancer by activating a specific biological process called Oxidative Stress. Hence, do not eat Amaranth with Cisplatin treatment for this Cancer. (A J van den Berg et al, J Wound Care., 2003; Omar M E Abdel-Salam et al, J Med Food., 2014; Akihiro Homma et al, Cancer., 2009; Wangie Yu et al, Scientific Reports, 2018)

Beetroot : Beetroot contains active ingredients such as Citric Acid, Trans-trans-farnesol, Vitamin C and others. Citric Acid interferes with the impact of Cisplatin in Paranasal Sinus and Nasal Cavity Cancer by activating a specific biological process called Oxidative Stress. Hence, do not eat Beetroot with Cisplatin treatment for this Cancer. (A J van den Berg et al, J Wound Care., 2003; Omar M E Abdel-Salam et al, J Med Food., 2014; Akihiro Homma et al, Cancer., 2009; Wangie Yu et al, Scientific Reports, 2018)

Foods to Eat

Aloe Vera :  Aloe Vera contains active ingredients like Lupeol, Chrysophanol and Barbaloin. Intake of Lupeol along with Cisplatin treatment for Paranasal Sinus and Nasal Cavity Cancer causes a decrease in a specific biological process which is called Cell Cycle, and this is a very positive effect.  Aloe Vera hence should be eaten with Cisplatin treatment for this Cancer. (Sayantan Bhattacharyya et al, Cell Oncol (Dordr)., 2017; Helena T Yip et al, Arch Otolaryngol Head Neck Surg., 2006; Akihiro Homma et al, Cancer., 2009)

Avocado :  Avocado contains active ingredients like Beta-sitosterol, Quercetin and Oleic Acid. Intake of Beta-sitosterol along with Cisplatin treatment for Paranasal Sinus and Nasal Cavity Cancer causes a decrease in a specific biological process which is called Cell Cycle, and this is a very positive effect. Avocado hence should be eaten with Cisplatin treatment for this Cancer. (Zhang-Qi Cao et al, Front Pharmacol., 2019; Shanthi Sri Vundru et al, BMC Complement Altern Med., 2013; Helena T Yip et al, Arch Otolaryngol Head Neck Surg., 2006; Akihiro Homma et al, Cancer., 2009)

Should I take this Nutritional Supplement for Paranasal Sinus and Nasal Cavity Cancer?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Cisplatin treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Cisplatin treatment efficacy in this Cancer. Hence avoid taking Black Seed supplements with Cisplatin treatment. (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Oncol., 2019)

Example Foods to “Not Eat” and Eat with Fluorouracil treatment for Paranasal Sinus and Nasal Cavity Cancer

Foods to Avoid

Green Bean : Green Bean contains active ingredients such as Folic Acid, Vitamin C, Ferulic Acid and others. Folic Acid interferes with the impact of Fluorouracil in Paranasal Sinus and Nasal Cavity Cancer by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Green Bean with Fluorouracil treatment for this Cancer. (Elena Silva et al, J Nutr., 2017; Eun-Ji Kim et al, Oncotarget., 2018; Kyungsuk Jung et al, Cancers Head Neck., 2018)

Kohlrabi : Kohlrabi contains active ingredients such as Folic Acid, Vitamin C, Indole-3-carbinol and others. Folic Acid interferes with the impact of Fluorouracil in Paranasal Sinus and Nasal Cavity Cancer by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Kohlrabi with Fluorouracil treatment for this Cancer. (Elena Silva et al, J Nutr., 2017; Eun-Ji Kim et al, Oncotarget., 2018; Kyungsuk Jung et al, Cancers Head Neck., 2018)

Foods to Eat

Allspice :  Allspice contains active ingredients like Salicylic Acid, Eucalyptol, Gallic Acid. Intake of Salicylic Acid along with Fluorouracil treatment for Paranasal Sinus and Nasal Cavity Cancer causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Allspice hence should be eaten with Fluorouracil treatment for this Cancer. (Jinbo Fu et al, Scientific Reports., 2019; Shengping Lin et al, J BUON., Sep-Oct 2020; Eun-Ji Kim et al, Oncotarget., 2018; Kyungsuk Jung et al, Cancers Head Neck., 2018)

Almond :  Almond contains active ingredients like Salicylic Acid, Quercetin, Vitamin E. Intake of Salicylic Acid along with Fluorouracil treatment for this Cancer causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Almond hence should be eaten with Fluorouracil treatment for this Cancer. (Jinbo Fu et al, Scientific Reports., 2019; Shengping Lin et al, J BUON., Sep-Oct 2020; Eun-Ji Kim et al, Oncotarget., 2018; Kyungsuk Jung et al, Cancers Head Neck., 2018)

Should I take this Nutritional Supplement for Paranasal Sinus and Nasal Cavity Cancer?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP1A2 interactions with Fluorouracil treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Fluorouracil treatment efficacy in this Cancer. Hence avoid taking Black Seed supplements with Fluorouracil treatment. (Ahmed A Albassam et al, Saudi Pharm J., 2018; T Komatsu et al, Drug Metab Dispos., 2000)

Which Foods To Avoid for Paranasal Sinus and Nasal Cavity Cancer?

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.

What are the Symptoms of this Cancer?

In the initial stages, most cancers including Paranasal Sinus and Nasal Cavity Cancer may not cause any signs or symptoms. However, as the disease progresses, it may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by this Cancer.

  • Nasal blockages causing stuffiness that does not go away
  • Nosebleeds
  • Nasal drainage in the back of the nose and throat
  • Loss or decreased sense of smell
  • Bulging of one eye
  • Headache
  • Hearing loss
  • Loss of sight
  • Vision problems like double vision
  • Constant watery eyes
  • Pain above or below the eye
  • A lump on the face, nose or top of the mouth
  • Numbness or pain in parts of your face
  • Loosening or numbness of the teeth
  • Difficulty opening the mouth
  • Enlarged lymph nodes in your neck
  • Pain/pressure in one of the ears

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Paranasal Sinus and Nasal Cavity Cancer.

What are the Treatment Options for this Cancer?

The treatment for Paranasal Sinus and Nasal Cavity Cancer may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for this Cancer include:

  • Surgery
  • Chemotherapy
  • Radiotherapy
  • Palliative therapy to handle symptoms

Surgery or surgery followed by radiation is the most common treatment regimen for this Cancer. Radiotherapy helps to shrink the tumor. The primary role of chemotherapy is in the treatment of metastatic disease. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for this Cancer.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Paranasal Sinus and Nasal Cavity Carcinoma.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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