addonfinal2

What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

()

Which 3 Foods to Avoid for B Cell Acute Lymphoblastic Leukemia (B-cell ALL)?

Apr 20, 2021

Home » Blogs » Which 3 Foods to Avoid for B Cell Acute Lymphoblastic Leukemia (B-cell ALL)?
You can also read this in

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for B Cell Acute Lymphoblastic Leukemia (B-cell ALL) needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Aloe Vera and Bamboo should be eaten when undergoing Doxorubicin treatment for B Cell Acute Lymphoblastic Leukemia. On the same lines, avoid foods like Corn and Guava with treatment of Doxorubicin for B Cell Acute Lymphoblastic Leukemia (B-cell ALL). Also, Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Doxorubicin treatment and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like B Cell Acute Lymphoblastic Leukemia.



What is B Cell Acute Lymphoblastic Leukemia (B-cell ALL)?

B Cell Acute Lymphoblastic Leukemia is a rare cancer that affects the B-cells or B-lymphocytes, the white blood cells that grow in the bone marrow. The incidence rate of this cancer is only 1 – 4.75 per 1 lakh people per year. This cancer is commonly diagnosed in adults who are about 40 years of age and children who are aged under 15 years, however, it can occur in people of any age. It is slightly more commonly found in males as compared to females.

B Cell Acute Lymphoblastic Leukemia (B-cell ALL) - Symptoms, Treatment, Diet, Foods

B-cell ALL has prevalence of certain genetic changes. Some of the genes such as TP53, KMT2D, CREBBP, and KRAS are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in B-cell ALL can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for B-cell ALL Leukemia. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of B-cell ALL genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer may have to be redesigned.

Why Eating Right Matters for B Cell Acute Lymphoblastic Leukemia?

In B Cell Acute Lymphoblastic Leukemia, activation or inhibition of some of the biochemical pathways including Oxidative Stress, Apoptosis, Hypoxia, MAPK Signaling, P53 Signaling, Cell Cycle Checkpoints, Macrophage M1, Amino Acid Metabolism, Vitamin D Signaling, Angiogenesis, Myc Signaling, Wnt Beta-catenin Signaling, Cancer Epigenetics, Epithelial To Mesenchymal Transition and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of B-cell ALL, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Doxorubicin treatment for B Cell Acute Lymphoblastic Leukemia

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for B-cell ALL considering only one specific treatment.

Foods to Avoid

Corn : Corn contains active ingredients such as Aescin, Oleic Acid, Chrysoeriol and others. Aescin interferes with the impact of Doxorubicin in B Cell Acute Lymphoblastic Leukemia by blocking a specific biological process called Cell Cycle Checkpoints. Hence, avoid foods like Corn with Doxorubicin treatment for B-cell ALL.

Guava : Guava contains active ingredients such as Casuarinin, Oleic Acid, Myricetin and others. Casuarinin interferes with the impact of Doxorubicin in B Cell Acute Lymphoblastic Leukemia by blocking a specific biological process called Oxidative Stress. Hence, avoid foods like Guava with Doxorubicin treatment for B-cell ALL. (Ji Hoon Song et al, Bioorg Med Chem Lett., 2017; Nour Shakir Rezaieg and Mohammed H. Musleh, IOP Conf. Series: Journal of Physics: Conf. Series 1294, 2019; C Friesen et al, Cell Death Differ., 1999; H M Kantarjian et al, J Clin Oncol., 1990)

Foods to Eat

Aloe Vera :  Aloe Vera contains active ingredients like Lupeol, Acemannan, Chrysophanol. Intake of Lupeol along with Doxorubicin treatment for B Cell Acute Lymphoblastic Leukemia causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Aloe Vera hence should be eaten with Doxorubicin treatment for B-cell ALL. (Mohammad Saleem et al, Oncogene., 2004; Maria Carolina S Moraes et al, Cancer Lett., 2012; S Köhrer et al, Leukemia., 2016)

Bamboo :  Bamboo contains active ingredients like Beta-sitosterol, Oleic Acid, Linolenic Acid. Intake of Beta-sitosterol along with Doxorubicin treatment for B-cell ALL causes a decrease  in a specific biochemical pathway which is called  PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bamboo hence should be eaten with Doxorubicin treatment for B-cell ALL. (Zhang-Qi Cao et al, Front Pharmacol., 2020; Maria Carolina S Moraes et al, Cancer Lett., 2012; S Köhrer et al, Leukemia., 2016)

Foods to eat and avoid for B Cell Acute Lymphoblastic Leukemia

Should I take this Nutritional Supplement for B Cell Acute Lymphoblastic Leukemia?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Doxorubicin treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Doxorubicin treatment efficacy in B-cell ALL. Hence avoid taking Black seed supplements with Doxorubicin treatment for this cancer.  (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Oncol., 2019)

Which 3 Foods to Avoid for B Cell Acute Lymphoblastic Leukemia (B-cell ALL)?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of B Cell Acute Lymphoblastic Leukemia (B-cell ALL)?

In the initial stages, most cancers including B Cell Acute Lymphoblastic Leukemia (B-cell ALL) may not cause any signs or symptoms. However, as the disease progresses, B-cell ALL may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by B-cell ALL.

  • Shortness of breath
  • Repeated infections
  • Bruising easily
  • Frequent Nosebleeds or bleeding gums

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of B-cell ALL.

What are the Treatment Options for B-cell ALL?

The treatment for B Cell Acute Lymphoblastic Leukemia may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history. The treatment options for B Cell Acute Lymphoblastic Leukemia (B-cell ALL) include:

  • Chemotherapy
  • Stem cell Transplantation
  • Targeted Therapy
  • CAR T-cell therapy (gene therapy)

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for B-cell ALL.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as B-cell ALL.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


How useful was this post?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?