No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Gemistocytic Astrocytoma (WHO Grade 2 Astrocytoma) needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Cabbage and Cucumber should be eaten when undergoing Radiation treatment for Gemistocytic Astrocytoma (WHO Grade 2 Astrocytoma). On the same lines, avoid foods like Kohlrabi and Kumquat with treatment of Radiation for Gemistocytic Astrocytoma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Gemistocytic Astrocytoma (WHO Grade 2 Astrocytoma).
What is Gemistocytic Astrocytoma (Grade 2 Astrocytoma)?
Gemistocytic Astrocytoma is a rare type of Grade 2 diffuse astrocytoma (WHO Classification), a cancer with poorer prognosis that develops from the cells called astrocytes which support nerve cells. The incidence rate of this cancer is only 0.04 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 50 years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.
What are the Causes of Gemistocytic Astrocytoma (Grade 2 Astrocytoma)?
The cause of Gemistocytic Astrocytoma (Grade 2 Astrocytoma) is not clear. However, hereditary syndromes due to inherited DNA mutations can be a cause for Gemistocytic Astrocytoma. Environmental factors like exposure to ionizing radiation and ultraviolet rays may also cause Gemistocytic Astrocytoma. Other possible causes for Gemistocytic Astrocytoma include diet, stress and lifestyle.
Genetic Abnormalities in Gemistocytic Astrocytoma (Grade 2 Astrocytoma)
Gemistocytic Astrocytoma has prevalence of certain genetic changes. Some of the genes such as IDH1, TP53, ATRX, and FOXO3 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Gemistocytic Astrocytoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Gemistocytic Astrocytoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Gemistocytic Astrocytoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer may have to be redesigned.
Why Eating Right Matters for Gemistocytic Astrocytoma?
In Gemistocytic Astrocytoma, activation or inhibition of some of the biochemical pathways including Notch Signaling, NFKB Signaling, PI3K-AKT-MTOR Signaling, Myc Signaling, Cell Cycle, P53 Signaling, C-type Lectin Receptor Signaling, JAK-STAT Signaling, Epithelial To Mesenchymal Transition, TGFB Signaling, DNA Repair, Cancer Epigenetics, RAS-RAF Signaling, MAPK Signaling, Cell Survival and Oxidative Stress plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Gemistocytic Astrocytoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Radiation treatment for Gemistocytic Astrocytoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Gemistocytic Astrocytoma considering only the treatment changes.
Foods to Avoid
Kohlrabi : Kohlrabi contains active ingredients such as Brassinin, Indole-3-carbinol, Oleic Acid and others. Brassinin interferes with the impact of Radiation in Gemistocytic Astrocytoma by blocking a specific biological process called Oxidative Stress. Hence, avoid foods like Kohlrabi with Radiation treatment for Gemistocytic Astrocytoma.
Kumquat : Kumquat contains active ingredients such as Apigenin, Retinol, Linolenic Acid and others. Apigenin interferes with the impact of Radiation in Gemistocytic Astrocytoma by blocking a specific biological process called Oxidative Stress. Hence, do not eat Kumquat with Radiation treatment for this cancer.
Foods to Eat
Cabbage : Cabbage contains active ingredients like Benzyl Isothiocyanate, Indole-3-carbinol and Quercetin. Intake of Benzyl Isothiocyanate along with Radiation treatment for Gemistocytic Astrocytoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Cabbage hence should be eaten with Radiation treatment for this cancer.
Cucumber : Cucumber contains active ingredients like Lupeol, Retinol and Salicylic Acid. Intake of Lupeol along with Radiation treatment for Gemistocytic Astrocytoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Cucumber hence should be eaten with Radiation treatment for this cancer.
Should I take this Nutritional Supplement for Gemistocytic Astrocytoma?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Radiation treatment. Black Seed supports the Radiation treatment for Gemistocytic Astrocytoma by decreasing the biochemical pathways/processes called Cell Survival, Epithelial to Mesenchymal Transition, MAPK Signaling, JAK-STAT Signaling, MYC Signaling, NFKB Signaling, Notch Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle, DNA Repair, TGFB Signaling, C-type Lectin Receptor Signaling, and RAS-RAF Signaling and increasing pathways like Oxidative Stress.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Gemistocytic Astrocytoma?
In the initial stages, most cancers including Gemistocytic Astrocytoma may not cause any signs or symptoms. However, as the disease progresses, it may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Gemistocytic Astrocytoma.
- Headache due to intracranial pressure
- Weakness on one side of the body
- Vision problems
- Loss of balance
- Weight loss or gain
- Change in behavior
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Gemistocytic Astrocytoma.
What are the Treatment Options for Gemistocytic Astrocytoma?
The treatment for Gemistocytic Astrocytoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for this cancer include:
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Gemistocytic Astrocytoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Gemistocytic Astrocytoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.