No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Myoepithelial Carcinoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Butter and Cabbage should be eaten when undergoing Radiation treatment for Myoepithelial Carcinoma. On the same lines, foods like Common Bean and Heart Of Palm should be avoided with treatment of Radiation for Myoepithelial Carcinoma. Also, Vitamin B2 supplements may interfere with the impact of Radiation in Myoepithelial Carcinoma and should be avoided.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Myoepithelial Carcinoma.
What is Myoepithelial Carcinoma?
Myoepithelial Carcinoma is a rare cancer that usually develops in the salivary glands, but can also occur in skin and soft tissues. The incidence rate of this cancer in 2012 was only 0.025-0.058 per 1 lakh people per year (Xiaofei Zhang et al, Transl Cancer Res., 2017). This cancer is commonly diagnosed in people who are about 50-60 years of age, however, it can occur in people of any age. It is more commonly found in women as compared to men.
Myoepithelial Carcinoma has prevalence of certain genetic changes. Some of the genes such as CRTC2, TP53, PTPRD, and POLD1 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Myoepithelial Carcinoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Myoepithelial Carcinoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Myoepithelial Carcinoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Myoepithelial Carcinoma nutrition may have to be redesigned.
Why Eating Right Matters for Myoepithelial Carcinoma?
In Myoepithelial Carcinoma, activation or inhibition of some of the biochemical pathways including MAPK Signaling, P53 Signaling, Oxidative Stress, NFKB Signaling, Cell Survival, JAK-STAT Signaling, Cell Cycle, C-type Lectin Receptor Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, MYC Signaling, DNA Repair and Epithelial To Mesenchymal Transition plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Myoepithelial Carcinoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Radiation treatment for Myoepithelial Carcinoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Myoepithelial Carcinoma considering only one specific treatment.
Foods to Avoid
Common Bean : Common Bean contains active ingredients such as Apigenin, P-coumaric Acid, Oleic Acid and others. Apigenin interferes with the impact of Radiation in Myoepithelial Carcinoma by activating a specific biological process called DNA Repair. Hence, do not eat Common Bean with Radiation treatment for Myoepithelial Carcinoma. (Haripaul Sharma et al, PLoS One., 2014; Julian Biau et al, Front Oncol., 2019; Joseph A Miccio et al, J Pediatr Hematol Oncol., 2016)
Heart of Palm : Heart Of Palm contains active ingredients such as Folic Acid, Palmitic Acid, Retinol and others. Folic Acid interferes with the impact of Radiation in Myoepithelial Carcinoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Heart Of Palm with Radiation treatment for Myoepithelial Carcinoma. (Seong Yeon Hwang et al, Int J Mol Med., 2015; Olga C J Schuurbiers et al, J Thorac Oncol., 2009; Mahmoud Toulany et al, Mol Cancer Ther., 2008; Joseph A Miccio et al, J Pediatr Hematol Oncol., 2016)
Foods to Eat
Butter : Butter contains active ingredients like Daidzein, Butyric Acid, Oleic Acid. Intake of Daidzein along with Radiation treatment for Myoepithelial Carcinoma causes a decrease in a specific biochemical pathway which is called Cell Cycle, and this is a very positive effect. Butter hence should be eaten with Radiation treatment for this cancer. (Eun Jeong Choi et al, Phytomedicine., 2008; F Teyssier et al, Bull Cancer., 1999; Joseph A Miccio et al, J Pediatr Hematol Oncol., 2016)
Cabbage : Cabbage contains active ingredients like Benzyl Isothiocyanate, Delphinidin, Sulforaphane. Intake of Benzyl Isothiocyanate along with Radiation treatment for Myoepithelial Carcinoma causes a decrease in a specific biochemical pathway which is called Cell Cycle, and this is a very positive effect. Cabbage hence should be eaten with Radiation treatment for this cancer. (Ruifen Zhang et al, J Nutr., 2006; Ravi Prakash Sahu et al, Front Biosci (Elite Ed)., 2009; F Teyssier et al, Bull Cancer., 1999; Joseph A Miccio et al, J Pediatr Hematol Oncol., 2016)
Should I take this Nutritional Supplement for Myoepithelial Carcinoma?
Vitamin B2 : Vitamin B2 nutritional supplements have no interactions with Radiation treatment. However, Vitamin B2 supplement interferes with the impact of Radiation in Myoepithelial Carcinoma by decreasing the biological process called Oxidative Stress. Hence, do not take Vitamin B2 supplements with Radiation treatment for Myoepithelial Carcinoma. (Karoline C Manthey et al, J Nutr Biochem., 2006; Joseph A Miccio et al, J Pediatr Hematol Oncol., 2016)
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of this Cancer?
In the initial stages, most cancers including Myoepithelial Carcinoma may not cause any signs or symptoms. However, as the disease progresses, based on the location, Myoepithelial Carcinoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Myoepithelial Carcinoma.
- Painless mass
- Hoarseness in voice
- Nasal blockage
- Nasal Bleeding
- Facial weakness
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Myoepithelial Carcinoma.
What are the Treatment Options for this Cancer?
The treatment for Myoepithelial Carcinoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Myoepithelial Carcinoma include:
- Chemotherapy – usually used in advanced cases (often in combination with radiotherapy)
- Palliative care
Surgery or surgery followed by radiation is the most common treatment regimen for Myoepithelial Carcinoma. Radiotherapy helps to shrink the tumor. The primary role of chemotherapy is in the treatment of metastatic disease. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Myoepithelial Carcinoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Myoepithelial Carcinoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.