No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Ganglioglioma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Almond and Apricot should be eaten when undergoing Hydroxyurea treatment for Ganglioglioma. On the same lines, foods like Amaranth and Beetroot should be avoided with treatment of Hydroxyurea for Ganglioglioma. Vitamin B2 supplements do not show benefit on biochemical pathways that could improve the Hydroxyurea treatment efficacy in Ganglioglioma and hence should be avoided while undergoing this treatment.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Ganglioglioma.
What is Ganglioglioma?
Ganglioglioma is a slow growing, rare cancer that develops anywhere in the central nervous system and most frequently occurs in the temporal lobes. This rare type of brain tumor contains a mixture of both glial cells, that provides structural support of the central nervous system, and neuronal cells, which is the functioning component of the central nervous system. The incidence rate of this cancer is only 0.26-0.29 per 1 lakh people per year. This cancer is commonly diagnosed in children and young adults, however, it can occur in people of any age. It is slightly more commonly found in men as compared to women. (Shlomit Yust-Katz et al, Neuro Oncol., 2014)
Ganglioglioma has prevalence of certain genetic changes. Some of the genes such as BRAF, EME1, TERT, and ZFHX3 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Ganglioglioma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Ganglioglioma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Ganglioglioma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Ganglioglioma nutrition may have to be redesigned.
Why Eating Right Matters for Ganglioglioma?
In Ganglioglioma, activation or inhibition of some of the biochemical pathways including MAPK Signaling, PI3K-AKT-MTOR Signaling, DNA Repair, RAS-RAF Signaling, MYC Signaling, Cell Cycle Checkpoints, Apoptosis and JAK-STAT Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Ganglioglioma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Hydroxyurea treatment for Ganglioglioma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Ganglioglioma considering only one specific treatment- Hydroxyurea.
Foods to Avoid
Amaranth and Beetroot : Amaranth and Beetroot contain active ingredients such as Folic Acid, Linoleic Acid and others. Folic Acid interferes with the impact of Hydroxyurea in Ganglioglioma by blocking a specific biological process called Apoptosis. Hence, do not eat Amaranth and beetroot with Hydroxyurea treatment for Ganglioglioma. (Ms Michelle Claire Rudd et al, Neuro Oncol. 2018; R F Huang et al, J Nutr., 1999; L A Rodriguez et al, Neurosurgery., 1988)
Foods to Eat
Almond and Apricot : Almond and Apricot contain active ingredients like Quercetin, Linoleic Acid and others. Intake of Quercetin along with Hydroxyurea treatment for Ganglioglioma causes a decrease in a specific biochemical pathway which is called JAK-STAT Signaling, and this is a very positive effect. Almond and Apricot hence should be eaten with Hydroxyurea treatment for Ganglioglioma. (Jonathan Michaud-Levesque et al, Exp Cell Res., 2012; Alberto Alvarez-Larrán et al, Leukemia., 2021; L A Rodriguez et al, Neurosurgery., 1988)
Should I take this Nutritional Supplement for Ganglioglioma?
Vitamin B2 : Vitamin B2 nutritional supplements have no known CYP interactions with Hydroxyurea treatment. However, Vitamin B2 supplements do not show benefit on other biochemical pathways that could improve the Hydroxyurea treatment efficacy in Ganglioglioma. Hence, avoid taking Vitamin B2 supplements when undergoing Hydroxyurea treatment for Ganglioglioma.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Ganglioglioma?
In the initial stages, most cancers including Ganglioglioma may not cause any signs or symptoms. However, as the disease progresses, Ganglioglioma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Ganglioglioma.
- Nausea and vomiting
- Increased pressure within the brain
- Weakness on one side of the body
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Ganglioglioma.
What are the Treatment Options for Ganglioglioma?
The treatment for Ganglioglioma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Ganglioglioma include:
- Radiation therapy
- Targeted therapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Ganglioglioma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Ganglioglioma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.