No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Thymic Neuroendocrine Tumor needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Aloe Vera and Barley should be eaten when undergoing Octreotide treatment for Thymic Neuroendocrine Tumor. On the same lines, avoid foods like Buttermilk and Cherry should be avoided with treatment of Octreotide for Thymic Neuroendocrine Tumor. Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Octreotide treatment and hence should be avoided.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Thymic Neuroendocrine Tumor.
What is Thymic Neuroendocrine Tumor?
Thymic Neuroendocrine Tumor, also known as thymic carcinoid tumor, is a rare carcinoid tumor that develops from the thymus. The incidence rate of this cancer is only 0.02 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 60–74 years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.
Thymic Neuroendocrine Cancer has prevalence of certain genetic changes. Some of the genes such as APH1A, BCL9, HIST2H3D, and MCL1 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Thymic Neuroendocrine Tumor can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Thymic Neuroendocrine Tumor. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Thymic Neuroendocrine Tumor genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer may have to be redesigned.
Why Eating Right Matters for Thymic Neuroendocrine Tumor?
In Thymic Neuroendocrine Tumor, activation or inhibition of some of the biochemical pathways including Wnt Beta-catenin Signaling, Angiogenesis, MAPK Signaling, Cancer Epigenetics, Growth Factor Signaling, PI3K-AKT-MTOR Signaling and Cell Cycle plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Thymic Neuroendocrine Tumor, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Octreotide treatment for Thymic Neuroendocrine Tumor
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Thymic Neuroendocrine Tumor considering only one specific treatment.
Foods to Avoid with Octreotide treatment
Buttermilk : Buttermilk contains active ingredients such as Lauric Acid, Vitamin D3, Myristic Acid and others. Lauric Acid interferes with the impact of Octreotide in Thymic Neuroendocrine Tumor by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not take Buttermilk with Octreotide treatment for this cancer. (Yingying Meng et al, J Agric Food Chem., 2017; Marily Theodoropoulou et al, Cancer Res., 2006; Nicolas Girard, J Thorac Dis., 2017; Tadashi Sakane et al, Clin Lung Cancer. 2021)
Cherry : Cherry contains active ingredients such as Chrysin, Oleanolic Acid, Beta-sitosterol and others. Chrysin interferes with the impact of Octreotide in Thymic Neuroendocrine Tumor by activating a specific biochemical pathway called WNT Beta-catenin Signaling. Hence, avoid foods like Cherry with Octreotide treatment for Thymic Neuroendocrine Tumor. (Song Wang et al, Hepatogastroenterology., 2013; Nicolas Girard, J Thorac Dis., 2017)
Foods to Eat with Octreotide treatment
Aloe Vera : Aloe Vera contains active ingredients like Lupeol, Chrysophanol, Acemannan. Intake of Lupeol along with Octreotide treatment for Thymic Neuroendocrine Tumor causes a decrease in a specific biochemical pathway which is called Cell Cycle, and this is a very positive effect. Aloe Vera hence should be eaten with Octreotide treatment for this cancer (Yihao Wang et al, Onco Targets Ther., 2018; Nupoor Prasad, J Biosci., 2018; Nicolas Girard, J Thorac Dis., 2017)
Barley : Barley contains active ingredients like Vitamin C, Beta-sitosterol, Folic Acid. Intake of Vitamin C along with Octreotide treatment for Thymic Neuroendocrine Tumor causes a decrease in a specific biochemical pathway which is called Cell Cycle, and this is a very positive effect. Barley hence should be eaten with Octreotide treatment for this cancer. (Christopher G Thomas et al, J Cell Physiol., 2005; Sahar Olsadat Sajadian et al, Clin Epigenetics., 2016; Nicolas Girard, J Thorac Dis., 2017)
Should I take this Nutritional Supplement with Octreotide treatment?
Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Octreotide treatment, and hence should not be used. Also, Black Seed supplements do not show benefit on other biochemical pathways that could improve the Octreotide treatment efficacy in this Neuroendocrine Tumor. (Ahmed A Albassam et al, Saudi Pharm J., 2018, Xiaoyu Sun et al, BMC Gastroenterol., 2021)
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of this Cancer?
Thymic Neuroendocrine Tumor may not always cause any signs or symptoms. However, based on the size of the tumor and the position, Thymic Neuroendocrine Tumor may show certain symptoms.
Following are some of the signs and symptoms that may be caused by Thymic Neuroendocrine Tumor.
- Chest pain
- Swallowing difficulties
- Loss of appetite
- Weight loss
- Cough (with blood)
- Hoarseness in voice
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Thymic Neuroendocrine Tumor.
What are the Treatment Options for this Cancer?
The treatment for Thymic Neuroendocrine Tumor may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options include:
- Chemotherapy with Radiotherapy
- Statin analogues
- Targeted Therapies
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Thymic Neuroendocrine Tumor.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Thymic Neuroendocrine Tumor.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.