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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Histiocytosis?

Mar 25, 2021

Estimated reading time: 7 minutes
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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Histiocytosis needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Blackberry and Carrot should be eaten when undergoing Radiation treatment for Histiocytosis. On the same lines, foods like Catjang Pea and Chili Pepper should be avoided with treatment of Radiation for Histiocytosis. Vitamin B2 supplement interferes with the impact of Radiation in Histiocytosis and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Histiocytosis.



What is Histiocytosis?

Histiocytosis refers to a group of rare diseases characterized by an abnormal increase in the number of histiocytes (tissue macrophages). The incidence rate of histiocytosis is only 1 per 1 lakh people per year. This disorder is commonly diagnosed in children under 15 years of age, however, it can occur in people of any age. It is more commonly found in Hispanic population as compared to Non-Hispanic population. (Karina Braga Ribeiro et al, Pediatr Blood Cancer., 2015)

Histiocytosis - Symptoms, treatment, diet, foods

The group of diseases categorized under histiocytosis include Langerhans cell histiocytosis (LCH), juvenile xanthogranuloma (JXG), Erdheim-Chester Disease (ECD), hemophagocytic lymphohistiocytosis (HLH), Rosai-Dorfman Disease (RD) and malignant histiocytosis including certain kinds of leukemia and malignant tumors.

Histiocytosis has prevalence of certain genetic changes. Some of the genes such as BRAF, MAP2K1, KRAS, and MUC4 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Histiocytosis can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Histiocytosis. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Histiocytosis genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Histiocytosis nutrition may have to be redesigned.

Why Eating Right Matters for Histiocytosis?

In Histiocytosis, activation or inhibition of some of the biochemical pathways including Oxidative Stress, MAPK Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, MYC Signaling and C-type Lectin Receptor Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Histiocytosis, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Radiation treatment for Histiocytosis

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Histiocytosis considering only the treatment changes.

Foods to Avoid

Catjang Pea : Catjang Pea contains active ingredients such as Folic Acid, Melatonin, Palmitic Acid and others. Folic Acid interferes with the impact of Radiation in Histiocytosis by activating a specific biochemical pathway called RAS-RAF Signaling. Hence, do not eat Catjang Pea with Radiation treatment for Histiocytosis. (Jing Zhang et al, Int J Clin Exp Med., 2019; Jung, Myung-Hwan et al, Journal of the Korean Physical Society, Volume 67, Issue 8, pp.1444-1447, 2015; Gary Tran et al, J Am Acad Dermatol., 2018; James Laird et al, Int J Radiat Oncol Biol Phys., 2018)

Chili Pepper : Chili Pepper contains active ingredients such as Capsaicin, Vitamin C, Oleic Acid and others. Capsaicin interferes with the impact of Radiation in Histiocytosis by activating a specific biochemical pathway called MAPK Signaling. Hence, do not eat Chili Pepper with Radiation treatment for Histiocytosis. (S M Sweitzer et al, Pain., 2004; Jung, Myung-Hwan et al, Journal of the Korean Physical Society, Volume 67, Issue 8, pp.1444-1447, 2015; Olga Novosad et al, Klin Onkol., Spring 2018; James Laird et al, Int J Radiat Oncol Biol Phys., 2018)

Foods to Eat

Blackberry :  Blackberry contains active ingredients like Ellagic Acid, Myricetin, Quercetin. Intake of Ellagic Acid along with Radiation treatment for Histiocytosis causes a decrease  in a specific biochemical pathway which is called RAS-RAF Signaling, and this is a very positive effect.  Blackberry hence should be eaten with Radiation treatment for Histiocytosis. (Yi Chang et al, Evid Based Complement Alternat Med., 2013; Jung, Myung-Hwan et al, Journal of the Korean Physical Society, Volume 67, Issue 8, pp.1444-1447, 2015; Gary Tran et al, J Am Acad Dermatol., 2018; James Laird et al, Int J Radiat Oncol Biol Phys., 2018)

Carrot :  Carrot contains active ingredients like Linalool, Alpha-terpinyl Acetate, Beta-sitosterol. Intake of Linalool along with Radiation treatment for Histiocytosis causes a decrease  in a specific biochemical pathway which is called RAS-RAF Signaling, and this is a very positive effect.  Carrot hence should be eaten with Radiation treatment for Histiocytosis. (Boris Rodenak-Kladniew et al, Life Sci., 2018; Gary Tran et al, J Am Acad Dermatol., 2018; James Laird et al, Int J Radiat Oncol Biol Phys., 2018)

Foods to eat and avoid for Histiocytosis

Should I take this Nutritional Supplement for Histiocytosis?

Vitamin B2 : Vitamin B2 nutritional supplements have no interactions with Radiation treatment. However, Vitamin B2 supplement interferes with the impact of Radiation in Histiocytosis by decreasing the biological process called Oxidative Stress. (Karoline C Manthey et al, J Nutr Biochem., 2006; B Perillo et al, Exp Mol Med., 2020; James Laird et al, Int J Radiat Oncol Biol Phys., 2018)

Which Foods To Avoid for Histiocytosis?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Histiocytosis?

In the initial stages, most cancers including Histiocytosis may not cause any signs or symptoms. However, as the disease progresses, Histiocytosis may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Histiocytosis.

  • Bone Fractures
  • Bone pain
  • Red, scaly bumps in skin folds
  • Jaundice
  • Weight loss
  • Swelling of lymph nodes
  • Chest pain
  • Cough
  • Fever
  • Increased urination
  • Skin Rash
  • Difficulty in breathing
  • Thirst and increased drinking of fluids

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Histiocytosis.

What are the Treatment Options for Histiocytosis?

The treatment for Histiocytosis may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Histiocytosis include:

  • Surgery to remove lesions
  • Radiation therapy
  • Chemotherapy
  • Anti-inflammatory Drugs like Steroids
  • Bone Marrow / Stem cell transplantation

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Histiocytosis.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Histiocytosis.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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