Yimuphi umdlavuza ongazuza ngokufaka iCitrus Bioflavanoid ekudleni kwabo?

Amaphuzu avelele

I-Citrus Bioflavanoid yaziwa kabanzi ngezinzuzo zayo zezempilo futhi ivame ukusetshenziswa iziguli ezinomdlavuza nalabo abasengozini yofuzo. Kodwa-ke, ukuphepha nokusebenza kahle kweCitrus Bioflavanoid yeziguli ezinomdlavuza kuncike ezintweni eziningi ezifana nenkomba yomdlavuza, i-chemotherapy, ezinye izindlela zokwelapha, kanye nofuzo lwesimila. Ukwazi ukuthi okunye ukudla nezithako zokudla, okufana ne-grapefruit nesipinashi, kungase kuhlanganyele kabi nemithi yomdlavuza futhi kubangele ukusabela okubi kubalulekile.

Ukudla kubalulekile ekwelapheni umdlavuza njengoba kungathinta imiphumela yokwelashwa. Iziguli ezinomdlavuza kufanele zikhethe ngokucophelela futhi zihlanganise ukudla okufanele kanye nezithako zokudla ezidliwayo. Isibonelo, i-Citrus Bioflavanoid ingase izuze labo abane-Primary Inflammatory Myofibroblastic Tumor abathola i-Gemcitabine, kodwa kungase kungabi kuhle ezigulini ezithola i-Radiation for Primary Urethral Squamous Cell Carcinoma. Ngaphezu kwalokho, nakuba i-Citrus Bioflavanoid ingasiza abantu abanesici sengozi yofuzo "KIT", ingase ingaphakanyiswe kulabo abasengozini yofuzo ehlukile "CTNNB1". Ukwenza kube ngokwakho izinhlelo zokudla ezisuselwe empilweni, ukwelashwa, kanye nofuzo kubalulekile.

Ukuqonda ukuthi ukwenza isinqumo ngokufaneleka kweCitrus Bioflavanoid esigulini esinomdlavuza kudinga ukwenziwa umuntu ngamunye kubalulekile. Izici ezibalulekile njengohlobo lomdlavuza, izindlela zokwelapha, ukwakheka kofuzo, izingozi zofuzo, ubudala, isisindo somzimba, nendlela yokuphila zibalulekile ekunqumeni ukuthi iCitrus Bioflavanoid iyisinqumo esifanele yini. I-Genomics kanye ne-genomics, ikakhulukazi, ibhekwa njengento ebalulekile. Njengoba lezi zici zingashintsha, kubalulekile ukubuyekeza njalo futhi ulungise ukukhetha kokudla ukuze kufane nezinguquko zesimo sezempilo kanye nokwelashwa.

Sengiphetha, indlela ephelele yokukhetha ukudla ibalulekile, igxile emiphumeleni yonke yazo zonke izakhi ezisebenzayo ekudleni/izithasiselo ezifana neCitrus Bioflavanoid esikhundleni sokuhlola isithako ngasinye esisebenzayo ngokwehlukana noma ukuziba ngokuphelele. Lo mbono obanzi ukhuthaza indlela enengqondo nengokwesayensi yokuhlelela ukudla komdlavuza.

Ukufingqiwe Okufushane

Ukusetshenziswa kokudla okusekelwe ezitshalweni nezithasiselo, njengamavithamini, amakhambi, amaminerali, ama-probiotics, kanye nezithako ezihlukahlukene ezikhethekile, ziyakhula phakathi kweziguli ezinomdlavuza. Lezi zithako zenzelwe ukuletha ukugxila okuphezulu kwezithako ezithile ezisebenzayo, eziningi zazo ezitholakala ekudleni okuhlukile. Ukugxila kanye nokwehlukahlukana kwezithako ezisebenzayo kuyahluka phakathi kokudla okuphelele nezithako zokudla. Ukudla ngokuvamile kunikeza uhla lwezithako ezisebenzayo kodwa ekugxiliseni okuphansi, kuyilapho izithako zinikeza ukugxila okuphezulu kwezithako ezithile.

Uma kucatshangelwa imisebenzi eyahlukene yesayensi neyebhayoloji yesithako ngasinye esisebenzayo ezingeni lamangqamuzana, kubalulekile ukulandisa ngemiphumela ehlanganisiwe yalezi zingxenye lapho unquma ngokudla nezithako okumelwe uzidle noma cha.

Umbuzo obalulekile ophakamayo: Ingabe kufanele ufake iCitrus Bioflavanoid ekudleni kwakho njengento yokudla noma isengezo? Ingabe kuyancomeka ukuthi udle iCitrus Bioflavanoid uma unezakhi zofuzo ezitholakala kumdlavuza ohambisana nofuzo lwe-KIT? Kuthiwani uma esikhundleni salokho ingozi yakho yofuzo ivela ohlotsheni lofuzo lwe-CTNNB1? Ingabe kunenzuzo ukufaka iCitrus Bioflavanoid ekudleni kwakho uma kutholakala ukuthi une-Primary Urethral Squamous Cell Carcinoma, noma uma ukuxilongwa kwakho kuyi-Primary Inflammatory Myofibroblastic Tumor? Ngaphezu kwalokho, ukusebenzisa kwakho iCitrus Bioflavanoid kufanele kulungiswe kanjani uma welashwa nge-Gemcitabine noma uma uhlelo lwakho lokwelapha lusuka ku-Gemcitabine luye kuMisebe? Kubalulekile ukuqaphela ukuthi ukugomela okulula okufana ne-'Citrus Bioflavanoid kungokwemvelo, ngakho-ke kuhlale kunenzuzo' noma 'i-Citrus Bioflavanoid ithuthukisa ukungatheleleki' akwanele ekukhetheni ukudla/izithasiselo ezinolwazi.

Ukwengeza, kubalulekile ukuhlola kabusha ukufaneleka kokufaka iCitrus Bioflavanoid ekudleni kwakho uma kukhona izinguquko ohlelweni lwakho lokwelapha. Kafushane, lapho wenza izinqumo mayelana nokufaka ukudla noma izithasiselo ezifana neCitrus Bioflavanoid ekudleni kwakho ukuze uthole izinzuzo zayo, kufanele ucabangele imiphumela yonke ye-biochemical yazo zonke izithako, ucabangela izici ezifana nohlobo lomdlavuza, ukwelashwa okuqondile okwenzayo, izakhi zofuzo. izibikezelo, kanye nokukhetha kwendlela yokuphila.

Cancer

Umdlavuza useyinselele enkulu emkhakheni wezokwelapha, ngokuvamile obangela ukukhathazeka okusabalele. Kodwa-ke, intuthuko yakamuva iye yathuthukisa imiphumela yokwelashwa, ikakhulukazi ngezindlela zokwelashwa eziqondene nomuntu siqu, izindlela zokuqapha ezingahlaseli kusetshenziswa amasampula egazi namathe, kanye nokuthuthukiswa kwe-immunotherapy. Ukutholwa kusenesikhathi kanye nokungenelela okufika ngesikhathi kuye kwaba semqoka ekube nomthelela omuhle emiphumeleni yokwelapha iyonke.

Ukuhlolwa kwezakhi zofuzo kunikeza isithembiso esibalulekile ekuhloleni ingozi yomdlavuza kanye nokuba sengozini kusenesikhathi. Kodwa-ke, kubantu abaningi abanomdlavuza womndeni kanye nezakhi zofuzo, izinketho zokungenelela kwezokwelapha, ngisho nokuqapha okuvamile, ngokuvamile kunqunyelwe noma akukho. Lapho kutholakala ukuthi unohlobo oluthile lomdlavuza, njenge-Primary Inflammatory Myofibroblastic Tumor noma Primary Urethral Squamous Cell Carcinoma, amasu okwelapha kudingeka enziwe ngokwezifiso ngokusekelwe kufuzo lomuntu ngamunye, isigaba sesifo, kanye nezici ezifana neminyaka nobulili. ”

Ngemuva kokwelashwa, ukuqapha okuqhubekayo kubalulekile ukuze kutholwe noma yiziphi izimpawu zokubuya komdlavuza futhi nokwazisa izinqumo ezilandelayo. Iziguli eziningi ezinomdlavuza kanye nalezo ezisengozini zivame ukufuna izeluleko zokufaka ukudla okuthile nezithako zokudla ezikudlayo, okudlala indima ebalulekile ekuthathweni kwazo zonke izinqumo mayelana nokuphathwa kwezempilo.

Umbuzo obalulekile ngowokuthi ingabe kufanele kufakwe engcupheni yofuzo kanye nokuxilonga umdlavuza othize lapho unquma ngokukhetha ukudla, njengeCitrus Bioflavanoid. Ingabe ingozi yofuzo yomdlavuza osukela ekuguqukeni kwe-KIT inemithelela efanayo ye-biochemical pathway njengoguquko ku-CTNNB1? Ngokombono wokudla okunempilo, ingabe ubungozi obuhambisana ne-Primary Inflammatory Myofibroblastic Tumor bulingana ne-Primary Urethral Squamous Cell Carcinoma? Ngaphezu kwalokho, ingabe ukucatshangelwa kokudla kuhlala kunjalo kulabo abathola i-Radiation njengalabo abathola i-Gemcitabine? Lokhu kucatshangelwa kubalulekile ekwenzeni ukukhetha kokudla okunolwazi kubantu abanezingozi zofuzo ezahlukene kanye nokwelashwa komdlavuza.

I-Citrus Bioflavanoid - Isengezo Esinomsoco

Isengezo I-Citrus Bioflavanoid ihlanganisa uhla lwezithako ezisebenzayo, okuhlanganisa i-Vicenin 2, i-Tangeretin, i-Rutin, i-Quercetin ne-Nobiletin, ngayinye ekhona ngokugxila okuhlukahlukene. Lezi zithako zithonya izindlela zamangqamuzana, ikakhulukazi i-MYC Signaling, i-DNA Repair, i-Apoptosis kanye ne-Growth Factor Signaling, elawula izici ezibucayi zomdlavuza ezingeni lamangqamuzana, njengokukhula kwesimila, ukusabalala, nokufa kwamangqamuzana. Njengoba kunikezwe leli thonya lebhayoloji, ukukhetha izithasiselo ezifanele njengeCitrus Bioflavanoid, iyodwa noma ihlangene, kuba yisinqumo esibucayi kumongo wokudla okunomdlavuza. Uma ucabangela ukusebenzisa i-Citrus Bioflavanoid yomdlavuza, kubalulekile ukucabangela lezi zici nezindlela ezihlukahlukene. Lokhu kungenxa yokuthi, ngokufana nokwelashwa komdlavuza, ukusetshenziswa kweCitrus Bioflavanoid akusona isinqumo esifanelekile kuwo wonke umdlavuza kodwa sidinga ukwenziwa ngezifiso.

Ukukhetha I-Citrus Bioflavanoid Supplements

Ukubhekana nombuzo othi 'Kunini lapho kufanele ngiyigweme i-Citrus Bioflavanoid esimweni somdlavuza' kuyinselele ngoba impendulo iqondene nomuntu ngamunye kakhulu - imane nje 'Kuncike!'. Ngokufana nokuthi noma yikuphi ukwelashwa komdlavuza kungase kungasebenzi kuso sonke isiguli, ukubaluleka nokuphepha noma izinzuzo zeCitrus Bioflavanoid kuyahlukahluka kuye ngezimo zomuntu siqu. Izinto ezinjengohlobo oluthile lomdlavuza, izakhi zofuzo, ukwelashwa kwamanje, ezinye izithako ezithathwayo, imikhuba yokuphila, i-BMI, nanoma yikuphi ukungezwani komzimba nakho konke kunendima ekunqumeni ukuthi iCitrus Bioflavanoid ifanelekile noma kufanele igwenywe, kugcizelela ukubaluleka kokucatshangelwa komuntu siqu. ezinqumweni ezinjalo.

1. Ingabe I-Citrus Bioflavanoid Supplements izozuza Iziguli Eziyinhloko ze-Urethral Squamous Cell Carcinoma ezelashwa ngeRadiation?

I-Primary Urethral Squamous Cell Carcinoma ibonakala ngokuguquguquka okuthile kofuzo, okuyi-BLM, BRCA1 kanye ne-CTCF, okuholela ekuguqulweni kwezindlela ze-biochemical, ikakhulukazi i-Androgen Signaling kanye nokulungiswa kwe-DNA. Ukusebenza kokwelashwa komdlavuza, okufana neRadiation, kuncike endleleni yokusebenza kwayo kulezi zindlela ezithile. Isu elifanele libandakanya ukuvumelanisa isenzo sokwelashwa nezindlela ezishayela umdlavuza, ngaleyo ndlela kuqinisekiswe indlela yomuntu siqu nephumelelayo. Ezimweni ezinjalo, ukugwema ukudla noma izithasiselo zokudla okunomsoco ezingase zimelane nemiphumela yokwelashwa noma zinciphise lokhu kuqondanisa kubalulekile. Isibonelo, isithasiselo se-Citrus Bioflavanoid, esithinta Ukulungiswa kwe-DNA, kungase kungabi inketho elungile esimweni se-Primary Urethral Squamous Cell Carcinoma lapho ukhishwa ngemisebe. Lokhu kungenxa yokuthi kungase kubhebhethekise ukuqhubeka kwesifo noma kuphazamise ukusebenza kahle kokwelashwa. Lapho ukhetha uhlelo lokudla okunempilo, kubalulekile ukucabangela izici ezifana nohlobo lomdlavuza, ukwelashwa okuqhubekayo, ubudala, ubulili, i-BMI, indlela yokuphila, nanoma yikuphi ukuguqulwa kofuzo okwaziwayo.

2. Ingabe I-Citrus Bioflavanoid Supplements izozizuzisa Iziguli Eziyinhloko Zokuvuvukala kwe-Myofibroblastic Tumor ezilashwa nge-Gemcitabine?

I-Primary Inflammatory Myofibroblastic Tumor ibonakala ngokuguqulwa kofuzo okukhethekile, okufana ne-ARID2, FLT4 kanye ne-IGF1R, okuholela ezinguqukweni zezindlela ze-biochemical, ikakhulukazi i-MYC Signaling, i-Chromatin Remodeling, i-Angiogenesis, i-Growth Factor Signaling kanye ne-PI3K-AKT-MTOR Signaling. Ukusebenza kokwelashwa komdlavuza, njengeGemcitabine, kunqunywa ukusebenzisana kwayo nalezi zindlela. Inhloso ukuqinisekisa ukuthi ukwelashwa kuhambisana kahle nezindlela eziqhuba umdlavuza, okwenza kube nendlela yokwelapha yomuntu siqu. Kulo mongo, ukudla noma izithasiselo ezihambisana nokwelashwa noma ezithuthukisa lokhu kuqondanisa kufanele kucatshangelwe. Isibonelo, isithasiselo se-Citrus Bioflavanoid siyinketho enengqondo yalabo abane-Primary Inflammatory Myofibroblastic Tumor ababhekana ne-Gemcitabine. Lokhu kungenxa yokuthi i-Citrus Bioflavanoid ithonya izindlela ezifana ne-MYC Signaling, engavimbela izici ezishayela I-Primary Inflammatory Myofibroblastic Tumor noma izuzise ukusebenza kahle kwe-Gemcitabine.

3. Ingabe I-Citrus Bioflavanoid Supplements Iphephile Kubantu Abanempilo Ene-CTNNB1 Mutation Associated Genetic Risk?

Izinkampani ezehlukene zihlinzeka ngamaphaneli ofuzo okuhlola ubungozi bofuzo lwezinhlobo ezahlukene zomdlavuza. Lawa maphaneli ahlanganisa izakhi zofuzo ezixhumene nomdlavuza webele, wesibeletho, isibeletho, i-prostate, kanye nomdlavuza wesisu. Ukuhlola lezi zakhi zofuzo kungaqinisekisa ukuxilongwa futhi kwazise amasu okwelashwa nawokuphatha. Ukuhlonza okuhlukile okubangela isifo kungasiza ngokuqhubekayo ekuhlolweni nasekuxilongeni izihlobo okungenzeka zibe sengozini. Ufuzo lwe-CTNNB1 luvamise ukufakwa kulawa maphaneli okuhlolwa kwengozi yomdlavuza.

Ukuguqulwa kofuzo lwe-CTNNB1 kuthinta izindlela zamakhemikhali ezinto eziphilayo noma izinqubo, ezifana ne-Apoptosis, i-Adherens junction kanye ne-Epithelial to Mesenchymal Transition, ezibandakanyeka ngokuqondile noma ngokungaqondile ekushayeleni umdlavuza ezingeni lamangqamuzana. Lapho iphaneli yofuzo ihlonza ukuguqulwa kwezakhi zofuzo ku-CTNNB1 okuhlobene nengozi eyengeziwe ye-Adrenocortical Carcinoma, ingqondo yesayensi iphakamisa ukugwema ukusetshenziswa kwesithasiselo se-Citrus Bioflavanoid. Lokhu kungenxa yokuthi isengezo se-Citrus Bioflavanoid sithonya izindlela ezifana ne-Apoptosis, ezingaholela emiphumeleni emibi kumongo wokuguqulwa kwe-CTNNB1 kanye nezimo zomdlavuza ezihlobene.

4. Ingabe I-Citrus Bioflavanoid Supplements Iphephile Kubantu Abanempilo Ene-KIT Mutation Associated Genetic Risk?

I-KIT idlala indima ebalulekile ekuhloleni ubungozi bomdlavuza. Ukuguqulwa kwezakhi zofuzo ku-KIT kungaphazamisa izindlela ezibalulekile zamakhemikhali ezinto eziphilayo, okuhlanganisa i-Growth Factor Signaling, enomthelela ekuthuthukisweni komdlavuza. Uma iphaneli yakho yofuzo yembula izinguquko ku-KIT ezihlobene Nomdlavuza Wesisu, cabanga ukufaka izithako ze-Citrus Bioflavanoid ohlelweni lwakho lokudla. Lezi zithako zingaba nomthelela omuhle ezindleleni ezifana ne-Growth Factor Signaling, zizuze ngokunikeza usekelo olufanele kubantu abanokuguqulwa kwe-KIT kanye nokukhathazeka kwezempilo okuhlobene.

Ekuphetheni

Izinto ezimbili ezibaluleke kakhulu okufanele uzikhumbule ukuthi ukwelapha umdlavuza kanye nokudla okunomsoco akufani kuwo wonke umuntu. Ukudla okunomsoco, okuhlanganisa ukudla nezithasiselo ezifana neCitrus Bioflavanoid, iyithuluzi elisebenzayo elingalawulwa nguwe ngenkathi ubhekene nomdlavuza.

“Kufanele ngidleni?” umbuzo ovame ukubuzwa yiziguli ezinomdlavuza nalabo abasengozini yomdlavuza. Impendulo efanele ukuthi incike ezintweni ezifana nohlobo lomdlavuza, ufuzo lwesimila, ukwelashwa kwamanje, ukungezwani komzimba nezinto ezithile, indlela yokuphila, kanye ne-BMI.

Thola umsoco wakho womdlavuza ku-addon ngokuchofoza isixhumanisi esingezansi futhi uphendule imibuzo emayelana nohlobo lomdlavuza wakho, ukwelashwa, indlela yokuphila, izinto ezingezwani nazo, iminyaka, nobulili.

Okubhekwayo

• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-oligonucleotides eyenza i-Triplex eqondise ku-c-MYC ingenza umsebenzi wokulwa nesimila we-gemcitabine kumodeli yegundane lomdlavuza womuntu.
• cBioPortal for Cancer Genomics
• I-Nobiletin Down-Regulates c-KIT Gene Expression futhi Isebenzisa Imithelela Ye-Antileukemic Kumaseli E-Human Acute Myeloid Leukemia.
• Umphumela we-apoptotic wezithelo ezisawolintshi ukhipha i-nobiletin kumugqa weseli yomdlavuza wamaphaphu A549 in vitro kanye ne-vivo.
• Isisho se-BRCA1 sibuyisela ukumelana nemisebe kumaseli omdlavuza anesici se-BRCA1 ngokuthuthukisa ukulungiswa kwe-DNA okulotshiweyo okuhlanganisiwe.
• [Ukwakhiwa okuyisisekelo kwemisebenzi yemfundo ekhethekile ekuvuseleleni abakhubazekile ngokomzimba].