Yimuphi umdlavuza ongahlomula ngokufaka i-Aloe Vera ekudleni kwabo?

Amaphuzu avelele

I-Aloe Vera yaziwa kabanzi ngezinzuzo zayo zezempilo futhi ivame ukusetshenziswa iziguli ezinomdlavuza nalabo abasengozini yofuzo. Nokho, ukuphepha nokusebenza kahle kwe-Aloe Vera ezigulini ezinomdlavuza kuncike ezintweni eziningi ezifana nenkomba yomdlavuza, i-chemotherapy, ezinye izindlela zokwelapha, kanye nofuzo lwesimila. Ukwazi ukuthi okunye ukudla kanye nezithako zokudla, okufana ne-grapefruit nesipinashi, kungase kuhlanganyele kabi nemithi yomdlavuza futhi kubangele ukusabela okubi kubalulekile.

Ukudla kubalulekile ekwelapheni umdlavuza njengoba kungathinta imiphumela yokwelashwa. Iziguli ezinomdlavuza kufanele zikhethe ngokucophelela futhi zihlanganise ukudla okufanele kanye nezithako zokudla ezidliwayo. Isibonelo, i-Aloe Vera ingase izuze labo abane-Primary Penile Squamous Cell Carcinoma abathola i-Mitomycin, kodwa kungase kungabi kuhle ezigulini ezithola i-Ifosfamide ye-Primary Round Cell Sarcoma. Ngaphezu kwalokho, nakuba i-Aloe Vera ingasiza abantu abanesici sengozi yofuzo “CDH1”, ingase ingaphakanyiswe kulabo abasengozini yofuzo ehlukile. Ukwenza kube ngokwakho izinhlelo zokudla ezisuselwe empilweni, ukwelashwa, kanye nofuzo kubalulekile.

Ukuqonda ukuthi ukwenza isinqumo mayelana nokufaneleka kwe-Aloe Vera esigulini esinomdlavuza kudinga ukwenziwa komuntu ngamunye kubalulekile. Izici ezibalulekile njengohlobo lomdlavuza, izindlela zokwelapha, ukwakheka kofuzo, izingozi zofuzo, ubudala, isisindo somzimba, nendlela yokuphila zibalulekile ekunqumeni ukuthi i-aloe Vera iyisinqumo esifanele yini. I-Genomics kanye ne-genomics, ikakhulukazi, ibhekwa njengento ebalulekile. Njengoba lezi zici zingashintsha, kubalulekile ukubuyekeza njalo futhi ulungise ukukhetha kokudla ukuze kufane nezinguquko zesimo sezempilo kanye nokwelashwa.

Sengiphetha, indlela ephelele yokukhetha ukudla ibalulekile, igxile emiphumeleni isiyonke yazo zonke izingxenye ezisebenzayo ekudleni/izithasiselo ezifana ne-Aloe Vera esikhundleni sokuhlola isithako ngasinye esisebenzayo ngokwehlukana noma ukuziba ngokuphelele. Lo mbono obanzi ukhuthaza indlela enengqondo nengokwesayensi yokuhlelela ukudla komdlavuza.

Ukufingqiwe Okufushane

Ukusetshenziswa kokudla okusekelwe ezitshalweni nezithasiselo, njengamavithamini, amakhambi, amaminerali, ama-probiotics, kanye nezithako ezihlukahlukene ezikhethekile, ziyakhula phakathi kweziguli ezinomdlavuza. Lezi zithako zenzelwe ukuletha ukugxila okuphezulu kwezithako ezithile ezisebenzayo, eziningi zazo ezitholakala ekudleni okuhlukile. Ukugxila kanye nokwehlukahlukana kwezithako ezisebenzayo kuyahluka phakathi kokudla okuphelele nezithako zokudla. Ukudla ngokuvamile kunikeza uhla lwezithako ezisebenzayo kodwa ekugxiliseni okuphansi, kuyilapho izithako zinikeza ukugxila okuphezulu kwezithako ezithile.

Uma kucatshangelwa imisebenzi eyahlukene yesayensi neyebhayoloji yesithako ngasinye esisebenzayo ezingeni lamangqamuzana, kubalulekile ukulandisa ngemiphumela ehlanganisiwe yalezi zingxenye lapho unquma ngokudla nezithako okumelwe uzidle noma cha.

Umbuzo obalulekile ophakamayo: Ingabe kufanele ufake i-Aloe Vera ekudleni kwakho njengento yokudla noma isengezo? Ingabe kuyafaneleka ukuthi udle i-Aloe Vera uma unezakhi zofuzo ezitholakala kumdlavuza ohambisana nofuzo lwe-CDH1? Kuthiwani uma esikhundleni salokho ingozi yakho yofuzo ivela esakhiweni sofuzo? Ingabe kunenzuzo ukufaka i-Aloe Vera ekudleni kwakho uma kutholakala ukuthi une-Primary Round Cell Sarcoma, noma uma ukuxilongwa kwakho kuyi-Primary Penile Squamous Cell Carcinoma? Ngaphezu kwalokho, ukusebenzisa kwakho i-Aloe Vera kufanele kulungiswe kanjani uma welashelwa i-Mitomycin noma uma uhlelo lwakho lokwelapha lusuka ku-Mitomycin luye ku-Ifosfamide? Kubalulekile ukuqaphela ukuthi izisho ezilula njengokuthi 'i-Aloe Vera ingokwemvelo, ngakho-ke ihlale inenzuzo' noma 'I-Aloe Vera ithuthukisa ukungatheleleki' akwanele ekukhetheni ukudla/izithasiselo ezinolwazi.

Ukwengeza, kubalulekile ukuhlola kabusha ukufaneleka kokufaka i-Aloe Vera ekudleni kwakho uma kukhona izinguquko ohlelweni lwakho lokwelapha. Kafushane, lapho wenza izinqumo mayelana nokufaka ukudla noma izithasiselo ezifana ne-Aloe Vera ekudleni kwakho ukuze uthole izinzuzo zayo, kufanele ucabangele imiphumela yonke ye-biochemical yazo zonke izithako, ucabangela izici ezifana nohlobo lomdlavuza, ukwelashwa okuqondile okwenzayo, izakhi zofuzo. izibikezelo, kanye nokukhetha kwendlela yokuphila.

Cancer

Umdlavuza useyinselele enkulu emkhakheni wezokwelapha, ngokuvamile obangela ukukhathazeka okusabalele. Kodwa-ke, intuthuko yakamuva iye yathuthukisa imiphumela yokwelashwa, ikakhulukazi ngezindlela zokwelashwa eziqondene nomuntu siqu, izindlela zokuqapha ezingahlaseli kusetshenziswa amasampula egazi namathe, kanye nokuthuthukiswa kwe-immunotherapy. Ukutholwa kusenesikhathi kanye nokungenelela okufika ngesikhathi kuye kwaba semqoka ekube nomthelela omuhle emiphumeleni yokwelapha iyonke.

Ukuhlolwa kwezakhi zofuzo kunikeza isithembiso esibalulekile ekuhloleni ingozi yomdlavuza kanye nokuba sengozini kusenesikhathi. Kodwa-ke, kubantu abaningi abanomdlavuza womndeni kanye nezakhi zofuzo, izinketho zokungenelela kwezokwelapha, ngisho nokuqapha okuvamile, ngokuvamile kunqunyelwe noma akukho. Uma kutholakala ukuthi unohlobo oluthile lomdlavuza, njenge-Primary Penile Squamous Cell Carcinoma noma i-Primary Round Cell Sarcoma, amasu okwelapha kudingeka enziwe ngendlela oyifisayo ngokusekelwe kufuzo lwesimila somuntu, isigaba sesifo, kanye nezici ezifana neminyaka nobulili. ”

Ngemuva kokwelashwa, ukuqapha okuqhubekayo kubalulekile ukuze kutholwe noma yiziphi izimpawu zokubuya komdlavuza futhi nokwazisa izinqumo ezilandelayo. Iziguli eziningi ezinomdlavuza kanye nalezo ezisengozini zivame ukufuna izeluleko zokufaka ukudla okuthile nezithako zokudla ezikudlayo, okudlala indima ebalulekile ekuthathweni kwazo zonke izinqumo mayelana nokuphathwa kwezempilo.

Umbuzo obalulekile ngowokuthi ingabe kufanele kufakwe engcupheni yofuzo kanye nokuxilongwa okuthile komdlavuza lapho unquma ngokudla okukhethwa kukho, njenge-Aloe Vera. Ingabe ingozi yofuzo yomdlavuza obangelwa ukuguqulwa kwe-CDH1 inemiphumela efanayo ye-biochemical pathway njengokuguqulwa kofuzo? Ngokombono wokudla okunempilo, ingabe ingozi ehambisana ne-Primary Penile Squamous Cell Carcinoma ilingana ne-Primary Round Cell Sarcoma? Ngaphezu kwalokho, ingabe ukucatshangelwa kokudla kuhlala kunjalo kulabo abathola i-Ifosfamide njengalabo abathola i-Mitomycin? Lokhu kucatshangelwa kubalulekile ekwenzeni ukukhetha kokudla okunolwazi kubantu abanezingozi zofuzo ezahlukene kanye nokwelashwa komdlavuza.

I-Aloe Vera - Isengezo Esinomsoco

Isithasiselo se-Aloe Vera sihlanganisa uhla lwezithako ezisebenzayo, okuhlanganisa i-Lupeol, i-Chrysophanol, i-Barbaloin ne-Acemannan, ngayinye ekhona ngokugxila okuhlukahlukene. Lezi zithako zithonya izindlela zamangqamuzana, ikakhulukazi i-WNT Beta Catenin Signaling, Ukulungiswa KweDNA, I-PI3K-AKT-MTOR Signaling kanye ne-Adherens junction, elawula izici ezibucayi zomdlavuza ezingeni lamaselula, njengokukhula kwesimila, ukusabalala, nokufa kweseli. Uma kubhekwa leli thonya lebhayoloji, ukukhetha izithasiselo ezifanele njenge-Aloe Vera, iyodwa noma ihlangene, kuba yisinqumo esibucayi kumongo wokudla okunomdlavuza. Uma ucabangela ukusebenzisa i-Aloe Vera yomdlavuza, kubalulekile ukucabangela lezi zici nezindlela ezihlukahlukene. Lokhu kungenxa yokuthi, ngokufana nokwelashwa komdlavuza, ukusetshenziswa kwe-Aloe Vera akusona isinqumo esifanelekile kuwo wonke umdlavuza kodwa sidinga ukwenziwa ngezifiso.

Ukukhetha Izithako ze-Aloe Vera

Ukubhekana nombuzo othi 'Kufanele ngiyigweme nini i-Aloe Vera esimweni somdlavuza' kuyinselele ngoba impendulo iqondene nomuntu ngamunye kakhulu - imane nje 'Kuncike!'. Ngokufana nokuthi noma yikuphi ukwelashwa komdlavuza kungase kungasebenzi kuso sonke isiguli, ukubaluleka nokuphepha noma izinzuzo ze-Aloe Vera kuyehluka kuye ngezimo zomuntu siqu. Izinto ezinjengohlobo oluthile lomdlavuza, izakhi zofuzo, ukwelashwa kwamanje, ezinye izithako ezithathwayo, imikhuba yokuphila, i-BMI, nanoma yikuphi ukungezwani komzimba nezinto zonke zidlala indima ekunqumeni ukuthi i-Aloe Vera ifanelekile noma kufanele igwenywe, kugcizelela ukubaluleka kokucatshangelwa komuntu siqu. ezinqumweni ezinjalo.

1. Ingabe Izithasiselo ze-Aloe Vera zizozizuzisa Iziguli ze-Primary Round Cell Sarcoma ezelashwa nge-Ifosfamide?

I-Primary Round Cell Sarcoma ibonakala ngokushintsha kofuzo okuthile, okuyi-CIC, i-ATM ne-FBXW7, okuholela ekuguqulweni kwezindlela zamakhemikhali ezinto eziphilayo, ikakhulukazi Ukulungiswa Kwe-DNA, Izindawo Zokuhlola Umjikelezo Weseli, I-Antigen Presentation kanye Nokuguqulwa Kokuhumusha Kokuthunyelwa. Ukusebenza kokwelashwa komdlavuza, okufana ne-Ifosfamide, kuncike endleleni esebenza ngayo kulezi zindlela ezithile. Isu elifanele libandakanya ukuvumelanisa isenzo sokwelashwa nezindlela ezishayela umdlavuza, ngaleyo ndlela kuqinisekiswe indlela yomuntu siqu nephumelelayo. Ezimweni ezinjalo, ukugwema ukudla noma izithasiselo zokudla okunomsoco ezingase zimelane nemiphumela yokwelashwa noma zinciphise lokhu kuqondanisa kubalulekile. Isibonelo, isithasiselo se-Aloe Vera, esithinta Ukulungiswa Kwe-DNA, kungase kungabi yisinqumo esifanele esimweni se-Primary Round Cell Sarcoma lapho bethola i-Ifosfamide. Lokhu kungenxa yokuthi kungase kubhebhethekise ukuqhubeka kwesifo noma kuphazamise ukusebenza kahle kokwelashwa. Lapho ukhetha uhlelo lokudla okunempilo, kubalulekile ukucabangela izici ezifana nohlobo lomdlavuza, ukwelashwa okuqhubekayo, ubudala, ubulili, i-BMI, indlela yokuphila, nanoma yikuphi ukuguqulwa kofuzo okwaziwayo.

2. Ingabe Izithasiselo ze-Aloe Vera zizozizuzisa Iziguli Eziyinhloko ze-Penile Squamous Cell Carcinoma ezelashwa nge-Mitomycin?

I-Primary Penile Squamous Cell Carcinoma ikhonjwa ngokuguqulwa kofuzo okukhethekile, okufana ne-ABRAXAS1, PIK3CB kanye ne-NUP93, okuholela ezinguqukweni zemizila ye-biochemical, ikakhulukazi i-WNT Beta Catenin Signaling, Hematopoiesis kanye ne-Inositol Phosphate Signaling. Ukusebenza kokwelashwa komdlavuza, njenge-Mitomycin, kunqunywa ukusebenzisana kwayo nalezi zindlela. Inhloso ukuqinisekisa ukuthi ukwelashwa kuhambisana kahle nezindlela eziqhuba umdlavuza, okwenza kube nendlela yokwelapha yomuntu siqu. Kulo mongo, ukudla noma izithasiselo ezihambisana nokwelashwa noma ezithuthukisa lokhu kuqondanisa kufanele kucatshangelwe. Isibonelo, isithasiselo se-Aloe Vera siyindlela enengqondo yalabo abane-Primary Penile Squamous Cell Carcinoma abathola i-Mitomycin. Lokhu kungenxa yokuthi i-Aloe Vera ithonya izindlela ezifana ne-WNT Beta Catenin Signaling, engavimbela izici ezishayela i-Primary Penile Squamous Cell Carcinoma noma izuzise ukusebenza kahle kwe-Mitomycin.

3. Ingabe Izithasiselo ze-Aloe Vera Ziphephile Kubantu Abanempilo Eminye Abane-CDH1 Mutation Associated Genetic Risk?

I-CDH1 idlala indima ebalulekile ekuhloleni ubungozi bomdlavuza. Ukuguqulwa kwezakhi zofuzo ku-CDH1 kungaphazamisa izindlela ezibucayi zamakhemikhali ezinto eziphilayo, okuhlanganisa i-Adherens junction kanye ne-Epithelial to Mesenchymal Transition, okuthonya ukukhula komdlavuza. Uma iphaneli yakho yofuzo yembula izinguquko ku-CDH1 ehambisana Nomdlavuza Wesisu, cabanga ukufaka izithasiselo ze-Aloe Vera ohlelweni lwakho lokudla. Lezi zithako zingaba nomthelela omuhle ezindleleni ezifana ne-Adherens junction, zizuze ngokunikeza ukwesekwa okufanelekile kwabantu abanezinguquko ze-CDH1 kanye nokukhathazeka kwezempilo okuhlobene.

Ekuphetheni

Izinto ezimbili ezibaluleke kakhulu okufanele uzikhumbule ukuthi ukwelapha umdlavuza nokudla okunempilo akufani kuwo wonke umuntu. Ukudla okunomsoco, okuhlanganisa ukudla nezithasiselo ezifana ne-Aloe Vera, iyithuluzi elisebenzayo elingalawulwa nguwe ngenkathi ubhekene nomdlavuza.

“Kufanele ngidleni?” umbuzo ovame ukubuzwa yiziguli ezinomdlavuza nalabo abasengozini yomdlavuza. Impendulo efanele ukuthi incike ezintweni ezifana nohlobo lomdlavuza, ufuzo lwesimila, ukwelashwa kwamanje, ukungezwani komzimba nezinto ezithile, indlela yokuphila, kanye ne-BMI.

Thola umsoco wakho womdlavuza ku-addon ngokuchofoza isixhumanisi esingezansi futhi uphendule imibuzo emayelana nohlobo lomdlavuza wakho, ukwelashwa, indlela yokuphila, izinto ezingezwani nazo, iminyaka, nobulili.

Okubhekwayo

• I-Barbaloin Inciphisa Ukulimala Kwe-Mucosal Kumamodeli Okuhlola E-Rat Colitis Ngokulawula Ukuvuvukala kanye Nomzila Wophawu we-AMPK.
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• Ukuthuthukiswa komsebenzi wokulwa nokuvuvukala we-Aloe vera yezimpande ze-adventitious ngokushintshwa kwe-metabolites eyinhloko neyesibili nge-salicylic acid elicitation.
• Isizinda, Ukuhlanzwa, Izimpawu Zesakhiwo, Imisebenzi Yebhayoloji kanye Nezicelo Zemithi Ye-Acemannan, i-Polysaccharide evela ku-Aloe vera: Ukubuyekeza.
• Ukwelashwa komdlavuza kulolonga isimo sokufaneleka se-clonal hematopoiesis.
• cBioPortal for Cancer Genomics
• I-Gold-chrysophanol nanoparticles icindezela ukuqhubeka komdlavuza womuntu we-prostate ngokungasebenzisi isisho se-AKT kanye nokwenza i-apoptosis kanye nesizukulwane se-ROS ku-vitro kanye ne-vivo.
• Ukumelana ne-Mitomycin C okubangelwa i-TCF-3 overexpression ku-gastric cancer cell line MKN28 ihlotshaniswa ne-DT-diaphorase down-regulation.
• Ukushintsha okuphambene ekukhishweni kwesisekelo se-DNA kanye nokulungiswa kwe-strand break kunomthelela ekumelana ne-melphalan kumaseli amaningi e-myeloma.
• I-Barbaloin: umbiko omfushane wezici zayo zesayensi yezemithi nezokuhlaziya.