Ukudla kwe-Fibrosarcoma!

Isingeniso

Ukudla kwe-Fibrosarcoma kufanele kube okomuntu siqu kumuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Fibrosarcoma wuhlobo lomdlavuza olusuka ezicutshini ezine-fibrous zomzimba. Kungenzeka ezindaweni ezihlukahlukene, okuhlanganisa unyawo, umphambili, nomunwe. Ukubhala ngekhodi okunembile kwezokwelapha kusetshenziswa ikhodi efanele ye-ICD-10 kubalulekile ekubhalweni. Uhlaka lwe-pathology lunikeza imininingwane ebalulekile ezicini zamaseli e-fibrosarcoma. I-Radiology isiza ekuxilongeni nasekuhloleni i-fibrosarcoma, isiza ekuhleleni ukwelashwa. Izinketho zokwelapha ze-fibrosarcoma zingabandakanya ukuhlinzwa, ukwelashwa ngamakhemikhali, noma ukwelashwa ngemisebe, kuye ngendawo kanye nesiteji sesimila. Amazinga okusinda kwe-fibrosarcoma angahluka kuye ngezici ngazinye, njengezinga lesifo kanye nokusabela ekwelashweni. Ukuxilongwa kusenesikhathi kanye nokwelashwa ngokushesha kubalulekile ukuze kube nemiphumela engcono. Ukubona izimpawu nezici zobungozi ezihlobene ne-fibrosarcoma kungasiza ekutholeni kusenesikhathi nokungenelela. I-Fibrosarcoma nayo ingathinta izinja, futhi inqubo yokuxilongwa neyokwelashwa ingase yehluke. Ngokufuna usizo lwezokwelapha olufanele kanye nokuhlola izindlela zokwelapha ezitholakalayo, abantu abane-fibrosarcoma bangakwazi ukwandisa amathuba abo omphumela ophumelelayo.

Ku-Fibrosarcoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokondleka obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza onjenge-Fibrosarcoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengeFibrosarcoma?

Isibonelo, ingabe kunendaba ukuthi iCauliflower yemifino idliwa kakhulu uma iqhathaniswa ne-Olive? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneSoursop? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Common Walnut phezu kwe-European Chestnut kanye nama-pulses afana ne-Gram Bean phezu kwe-Lima Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Fibrosarcoma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Fibrosarcoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo iPummelo iqukethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lycopene, i-Quercetin, i-Phloretin. Futhi i-Soursop iqukethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Emodin, i-Fisetin, i-Phloretin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Fibrosarcoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Fibrosarcoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Fibrosarcoma?

Ukondleka komuntu siqu komdlavuza njengeFibrosarcoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-Fibrosarcoma, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelashwa komdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njengeFibrosarcoma

Yonke imidlavuza efana ne-Fibrosarcoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Fibrosarcoma. Izindlela ze-Biochemical ezifana ne-Apoptosis, Cell Cycle, MAPK Signaling, PI3K-AKT-MTOR Signaling ziyingxenye yencazelo yesiginesha ye-Fibrosarcoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenzayo kwe-Fibrosarcoma kudinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconyelwa i-Fibrosarcoma lapho uthatha ukwelashwa komdlavuza i-Eribulin, futhi okunye ukudla nezithako ezingeziwe akunconyiwe.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TP53, ATRX, PREX2, CYP17A1 kanye ne-BRAF yizakhi zofuzo ezisezingeni eliphezulu ezibikwayo ze-Fibrosarcoma. I-TP53 ibikwa kuma-23.5 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-ATRX ibikwa ku-23.5%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angama-53.7 emininingwane yesiguli ahlonzwa njengabesilisa. I-Fibrosarcoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelwe ukusayina izindlela ze-biochemical zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zeFibrosarcoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable CAULIFLOWER noma i-OLIVE?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Phloretin, i-Daidzein, i-Beta-sitosterol, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Cell Cycle, Epithelial to Mesenchymal Transition kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Cauliflower inconywa nge-Fibrosarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin. Lokhu kungenxa yokuthi uCauliflower uguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Eribulin.

Ezinye zezithako ezisebenzayo noma ama-bioactives kumifino ye-Olive yi-Curcumin, i-Quercetin, i-Phloretin, i-Hydroxytyrosol, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis ne-PI3K-AKT-MTOR Signaling nezinye. I-Olive ayinconyelwe i-Fibrosarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-VEGETABLE CAULIFLOWER INCONYISWA NGAPHEZU KOMNQUMO NGE-Fibrosarcoma KANYE NOKWELAPHA I-Eribulin.

Khetha isithelo SOURSOP noma i-PUMMELO?

I-Fruit Soursop iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Emodin, i-Fisetin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis, Cell Cycle kanye ne-MAPK Signaling nezinye. I-Soursop inconywa nge-Fibrosarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin. Lokhu kungenxa yokuthi i-Soursop iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Eribulin.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Lycopene, i-Quercetin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Epithelial kuya ku-Mesenchymal Transition kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Pummelo ayinconyelwe i-Fibrosarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ISITHELO SOURSOP INCONYISWA NGAPHEZU KWE-PUMMELO YE-Fibrosarcoma KANYE NOKWELAPHA I-Eribulin.

Khetha Nut COMMON WALNUT noma EUROPEAN CHESTNUT?

I-Walnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives njenge-Ellagic Acid, i-Curcumin, i-Quercetin, i-Phloretin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Cell Cycle, Epithelial to Mesenchymal Transition kanye ne-Apoptosis nezinye. I-Walnut evamile inconywa nge-Fibrosarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin. Lokhu kungenxa yokuthi i-Common Walnut iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Eribulin.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-European Chestnut yi-Ellagic Acid, i-Apigenin, i-Curcumin, i-Quercetin, i-Phloretin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut yase-Europe ayinconyelwe i-Fibrosarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Eribulin ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT EJWAYELEKILE INCONYISWA NGE-CHESTNUT YAseYurophu NGE-Fibrosarcoma KANYE NOKWELASHWA I-Eribulin.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo ye-Fibrosarcoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma isipinashi se-MUSTARD?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, i-Reproductive Hormone Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Giant Butterbur inconywa ngengozi ye-Fibrosarcoma lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yesipinashi yesinaphi yi-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints kanye ne-Oncogenic Cancer Epigenetics nezinye. Isipinashi se-Mustard asinconywa uma ingozi ye-Fibrosarcoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEMIJINO INCONYWA NGAPHEZU KWESIPINSHI SEMISTARD NGENGOZI YE-ATRX YOFUZO YOMFUZA.

Khetha Isithelo RED RASPBERRY noma i-GUAVA?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokusayina kwe-MAPK, Izindawo Zokuhlola Zeseli Lomjikelezo, Ukusayina kwe-RAS-RAF kanye Nokusayina kwe-TGFB nokunye. Okusajingijolo Okubomvu Kunconywa ngengozi ye-Fibrosarcoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Red Raspberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni iGuava i-Ellagic Acid, i-Apigenin, i-Curcumin, i-Quercetin, i-Linalool. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Guava ayinconywa uma ingozi ye-Fibrosarcoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba yandisa izindlela zayo zokusayina.

I-RASPBERRY EBOMVU ISITHELO INCONYISWA NGAPHEZU KWE-GUAVA YE-ATRX GENETIC RISK OF CANCER.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Lycopene, i-Myricetin, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokusayina kwe-MAPK, Izindawo Zokuhlola Zeseli Lomjikelezo, Ukusayina kwe-RAS-RAF kanye Nokusayina kwe-TGFB nokunye. I-Hazelnut evamile inconywa ngengozi ye-Fibrosarcoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Ellagic Acid, i-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut ayinconywa uma ingozi ye-Fibrosarcoma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT NGENGOZI YE-ATRX GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njengeFibrosarcoma. Iziguli ze-Fibrosarcoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithako zokudla okunconyelwe mina nezinganconyelwe?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Fibrosarcoma, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana nokholifulawa kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene futhi ahlukene emizila ye-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Fibrosarcoma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-Pelargonidin idala imiphumela ye-antitumor kumaseli e-osteosarcoma yomuntu ngokusebenzisa i-autophagy induction, ukulahlekelwa amandla olwelwesi lwe-mitochondrial, ukuboshwa komjikelezo we-G2/M kanye nokwehliswa kwendlela yokusayina ye-PI3K/AKT.
• I-Brassinin Icindezela Amathuba Okuhlaselayo Amaseli E-Carcinoma Emaphaphu Ngokuyekisa ukusebenza kwe-PI3K/Akt/mTOR Signaling Cascade.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• I-Melatonin ne-vitamin D3 i-synergistically down-regulate i-Akt ne-MDM2 eholela ekuvimbeleni ukukhula okuncike ku-TGFβ-1 kwamangqamuzana omdlavuza webele.
• https://www.ncbi.nlm.nih.gov/books/NBK560759
• https://my.clevelandclinic.org/health/diseases/22009-fibrosarcoma