Ukudla kwe-Erdheim Chester Disease!

Isingeniso

Ukudla kwe-Erdheim Chester Disease kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Erdheim-Chester Disease (ECD) iyivelakancane, engeyona eyeLangerhans cell histiocytosis, evame ukubhekwa njengomdlavuza, imbangela yaso ingaphansi kophenyo kodwa ngokuvamile ayibhekwa njengefa noma ifuzo. Okuphawuleka ngezimpawu ezihlukile njengobuhlungu bamathambo nokubonakaliswa kwemizwa, ukuxilongwa kwe-ECD kuhilela inhlanganisela yamasu e-radiological, okuhlanganisa i-CT ne-MRI yobuchopho, kanye nezinhlaka eziphelele ze-pathology. Amasu okwelapha e-Erdheim-Chester Disease ayaqhubeka nokuvela, ngolwazi olubuyekeziwe olufinyeleleka ngezinkundla ezifana ne-UpToDate kanye ne-Erdheim-Chester Disease Global Alliance. I-ECD ivamise ukufaka izinhlelo zezitho ezifana namaphaphu nobuchopho, kanti i-radiology ibalulekile ekuhloleni nasekuqaphelweni kwezifo. Njengoba ihlukaniswa ngaphansi kohlelo lwe-ICD-10, ukuphathwa kwe-ECD kukhanyiswa ngokubuyekezwa kanye nezifundo zezenzakalo, ezigqamisa ukubaluleka kocwaningo oluqhubekayo nokuqwashisa ekubhekaneni nalesi sifo esiyinkimbinkimbi.

Ku-Erdheim Chester Disease ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwe iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza njenge-Erdheim Chester Disease ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-Erdheim Chester Disease?

Isibonelo, ingabe kunendaba uma isitshalo seqanda semifino sidliwa kakhulu uma siqhathaniswa ne-Chayote? Ingabe kuyawenza umehluko uma izithelo ze-Sugar Apple zikhethwa kune-Arctic Blackberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Black Walnut phezu kwe-Macadamia Nut kanye nama-pulses afana nobhontshisi oluhlaza phezu kwe-Catjang Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe I-Erdheim Chester Disease futhi ingabe impendulo efanayo kuwo wonke umuntu onokuxilongwa okufanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Erdheim Chester Disease!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-apula likashukela liqukethe izithako ezisebenzayo i-Myricetin, i-Lycopene, i-Pelargonidin, i-Curcumin, i-Cinnamaldehyde. Futhi i-Arctic Blackberry iqukethe izithako ezisebenzayo i-Ellagic Acid, i-Lycopene, i-Curcumin, i-Quercetin, i-Cinnamaldehyde kanye nezinye okungenzeka.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa yi-Erdheim Chester Disease - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Erdheim Chester Disease.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Adingekayo Wokwenziwa Kokudla Ngokwakho Kwesifo Se-Erdheim Chester?

Ukondleka komuntu siqu komdlavuza njenge-Erdheim Chester Disease kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-Erdheim Chester Disease, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelashwa komdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Erdheim Chester Disease

Yonke imidlavuza efana ne-Erdheim Chester Disease ingabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-Erdheim Chester Disease. Izindlela ze-biochemical ezifana ne-RAS-RAF Signaling, i-MAPK Signaling, i-Cytoskeletal Dynamics, i-Angiogenesis iyingxenye yencazelo yesiginesha ye-Erdheim Chester Disease. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo eSifo i-Erdheim Chester zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa ngesifo i-Erdheim Chester lapho uthatha ukwelashwa komdlavuza i-Vemurafenib, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-MAP2K1, ARAF, ARID5B, BRAF kanye ne-MYCN yizakhi zofuzo ezikleliswe phezulu ze-Erdheim Chester Disease. I-MAP2K1 ibikwa ku-25.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-ARAF ibikwa ku-12.5%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angu-61.5 emininingwane yesiguli ahlonzwa njengabesilisa. I-biology ye-Erdheim Chester Disease kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele ukusayina izindlela ze-biochemical zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Erdheim Chester Disease

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable EGGPLANT noma i-CHAYOTE?

Isitshalo seqanda semifino siqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Myricetin, i-Isorhamnetin, i-Gallic Acid, i-Curcumin, i-Quercetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-RAS-RAF Signaling kanye ne-MAPK Signaling nezinye. Isitshalo seqanda sinconywa eSifo i-Erdheim Chester lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib. Lokhu kungenxa yokuthi isitshalo seqanda siguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Vemurafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chayote yemifino yi-Myricetin, i-Pelargonidin, i-Curcumin, i-Cinnamaldehyde, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-MAPK Signaling nezinye. I-Chayote ayinconyelwe Isifo se-Erdheim Chester lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-EGGPLANT EMIFINO INCONYISWA NGAPHEZU KWE-CHAYOTE YE-Erdheim Chester Disease KANYE NOKWELASHWA I-Vemurafenib.

Khetha Isithelo I-ARCTIC BLACKBERRY noma I-APPLE KASHUKELA?

I-Fruit Arctic Blackberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives njenge-Ellagic Acid, i-Lycopene, i-Curcumin, i-Quercetin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-RAS-RAF Signaling kanye ne-MAPK Signaling nezinye. I-Arctic Blackberry inconywa e-Erdheim Chester Disease lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib. Lokhu kungenxa yokuthi i-Arctic Blackberry iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Vemurafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-apula likashukela yiMyricetin, iLycopene, iPelargonidin, iCurcumin, iCinnamaldehyde. Lezi zithako ezisebenzayo zishintsha izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling nezinye. I-apula kashukela ayinconyelwe Isifo se-Erdheim Chester lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib ngoba ilungisa lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO I-ARCTIC BLACKBERRY INCONYISWA NGAPHEZU KWE-APPLE KASHUKELA NGESIFO I-Erdheim Chester KANYE NOKWELAPHA I-Vemurafenib.

Khetha Nut BLACK WALNUT noma MACADAMIA NUT?

I-Walnut Emnyama iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Myricetin, i-Ellagic Acid, i-Pelargonidin, i-Gallic Acid, i-Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling kanye ne-MAPK Signaling nezinye. I-Black Walnut inconywa eSifo i-Erdheim Chester lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib. Lokhu kungenxa yokuthi i-Black Walnut iguqula leyo migudu ye-biochemical ebikwe ngokwesayensi ukuze iqwashise umthelela we-Vemurafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Macadamia Nut yi-Myricetin, i-Pelargonidin, i-Curcumin, i-Cinnamaldehyde, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-MAPK Signaling nezinye. I-Macadamia Nut ayinconyelwe Isifo i-Erdheim Chester uma ukwelashwa komdlavuza okuqhubekayo kuyi-Vemurafenib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT EMNYAMA INCONYISWA NGAPHEZU KWE-MACADAMIA NUT YE-Erdheim Chester Isifo KANYE NOKWELAPHA I-Vemurafenib.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abanengozi yofuzo ye-Erdheim Chester Disease noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithasiselo ziba zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma IGARLAND CHRYSANTHEMUM?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Butterbur Enkulu iyanconywa ngengozi ye-Erdheim Chester Disease lapho ingozi yofuzo ehlotshaniswa nayo i-ARAF. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Garland Chrysanthemum yi-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-MAPK Signaling nezinye. I-Garland Chrysanthemum ayituswa uma ingozi ye-Erdheim Chester Disease uma ingozi yofuzo ehlotshaniswa nayo i-ARAF ngoba yandisa izindlela zayo zokusayina.

IBUTTERBUR OMKHULU WOKUMVUNO INCONYISWA NGAPHEZU KWE-GARLAND CHRYSANTHEMUM NGENGOZI YOMKHANZA YE-ARAF.

Khetha isithelo NANCE noma iPUMMELO?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Nance inconywa ngengozi ye-Erdheim Chester Disease lapho ubungozi bofuzo obuhambisanayo kuyi-ARAF. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Pummelo ayituswa uma ingozi ye-Erdheim Chester Disease uma ingozi yofuzo ehlotshaniswa nayo kuyi-ARAF ngoba yandisa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YOMKHANZA YE-ARAF GENETIC.

Khetha Nut COMMON HAZELNUT noma EUROPEAN CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Hazelnut evamile inconywa engozini ye-Erdheim Chester Disease lapho ingozi yofuzo ehlobene i-ARAF. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-European Chestnut yi-Apigenin, i-Ellagic Acid, i-Curcumin, i-Quercetin, i-Myricetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Chestnut yase-Europe ayinconywa uma ingozi ye-Erdheim Chester Disease uma ingozi yofuzo ehambisana nayo kuyi-ARAF ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT YAseYurophu NGENGOZI YOFUZO YE-ARAF YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Erdheim Chester Disease. Iziguli ze-Erdheim Chester Disease kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Erdheim Chester Disease, ngayinye ene-tumor genetics enokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Eggplant kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukene wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli I-Erdheim Chester Disease?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-Retinol yehlisa amazinga e-beta-catenin amaprotheni emigqeni yamaseli omdlavuza we-colon we-retinoic acid.
• I-Geraniol, ingxenye yamafutha abalulekile ezitshalo, iqwashisa amangqamuzana omdlavuza womuntu wekholoni ekwelashweni kwe-5-Fluorouracil.
• I-Chemoprevention ye-tumorigenesis yamathumbu nge-flavonoid yemvelo yokudla i-myricetin ku-APCMin/+ amagundane.
• Imiphumela yokuvikela iqhathaniswa nokuphromotha yetiye elimhlophe ne-caffeine ku-PhIP-induced tumorigenesis kanye nokuvezwa kwe-beta-catenin kugundane.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.
• https://medlineplus.gov/genetics/condition/erdheim-chester-disease/#resources
• https://rarediseases.org/rare-diseases/erdheim-chester-disease
• https://histio.org/histiocytic-disorders/erdheim-chester-disease
• https://www.lls.org/sites/default/files/2022-07/FS37_Erdheim_Chester_2022.pdf