Ukudla Okusabalalisa I-Glioma!

Isingeniso

Ukudla Kwe-Diffuse Glioma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ku-Diffuse Glioma, kunendaba ukuthi imifino, izithelo, amantongomane, imbewu umuntu udlani?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwe iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza onjenge-Diffuse Glioma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Diffuse Glioma?

Isibonelo, ingabe kunendaba ukuthi iJute yemifino idliwa kakhulu uma iqhathaniswa netheniphu? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneRed Raspberry? Futhi uma ukukhetha okufanayo kwenziwa ngamantongomane/imbewu efana ne-Almond phezu kwe-European Chestnut kanye nama-pulses afana ne-Black-eyed Pea phezu kwe-Common Bean. Futhi uma lokho engikudlayo kunendaba - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Diffuse Glioma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Diffuse Glioma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo iPummelo iqukethe izithako ezisebenzayo I-Caffeine, i-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin. Futhi okusajingijolo Okubomvu kuqukethe izithako ezisebenzayo i-Ellagic Acid, i-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin futhi mhlawumbe nabanye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Diffuse Glioma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Diffuse Glioma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Ukuze Uhlukanise I-Glioma?

Ukondleka komuntu siqu komdlavuza njenge-Diffuse Glioma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Diffuse Glioma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Diffuse Glioma

Yonke imidlavuza efana ne-Diffuse Glioma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Diffuse Glioma. Izindlela zamakhemikhali ezinto eziphilayo ezifana nokulungiswa kwe-DNA, Ukulungisa Okuqondile, Ukusayina kwe-PI3K-AKT-MTOR, i-Hypoxia ziyingxenye yencazelo yesiginesha ye-Diffuse Glioma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Diffuse Glioma zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconyelwa i-Diffuse Glioma lapho uthatha ukwelashwa komdlavuza i-Procarbazine, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-IDH1, TP53, ATRX, PTEN kanye ne-EGFR izakhi zofuzo ezisezingeni eliphezulu ezibikiwe ze-Diffuse Glioma. I-IDH1 ibikwa ku-50.1 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-TP53 ibikwa ku-39.3%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka yobudala esukela kweyi-10 kuye kwengama-89. Ama-59.0 % emininingwane yesiguli ahlonzwa njengabesilisa. I-Diffuse Glioma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithasiselo Zokusabalalisa I-Glioma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable JUTE noma i-TURNIP?

I-Vegetable Jute iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, i-NFKB Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Jute inconywa nge-Diffuse Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine. Lokhu kungenxa yokuthi i-Jute ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Procarbazine.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Tunip yemifino yi-Ellagic Acid, i-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-DNA Repair nezinye. Itheniphu ayinconyelwe i-Diffuse Glioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-JUTE YEMIJINO INCONYISWA PHEZU KWE-JINIKA YE-Diffuse Glioma KANYE NOKWELAPHA I-Procarbazine.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Ellagic Acid, i-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling, i-PI3K-AKT-MTOR Signaling, i-MAPK Signaling ne-Hypoxia nezinye. Okusajingijolo Okubomvu kunconyelwe i-Diffuse Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine. Lokhu kungenxa yokuthi i-Red Raspberry iguqula lezo zindlela ze-biochemical ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Procarbazine.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Caffeine, i-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress and DNA Repair nezinye. I-Pummelo ayinconyelwe i-Diffuse Glioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-RASPBERRY YESITHELO EBOMVU INCONYISWA NGAPHEZU KWE-PUMMELO YE-Diffuse Glioma KANYE NOKWELASHWA I-Procarbazine.

Khetha Nut ALMOND noma EUROPEAN CHESTNUT?

I-almond iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Daidzein, i-Isoliquiritigenin, i-Phloretin, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling, Hedgehog Signaling, PI3K-AKT-MTOR Signaling kanye ne-Hypoxia nezinye. I-almond inconyelwe i-Diffuse Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine. Lokhu kungenxa yokuthi i-Almond ilungisa leyo migudu ye-biochemical ebikwe ngokwesayensi ukuze iqwashise umthelela we-Procarbazine.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Ellagic Acid, i-Myricetin, i-Curcumin, i-Daidzein, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress and DNA Repair nezinye. I-Chestnut yase-Europe ayinconyelwe i-Diffuse Glioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Procarbazine ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-ALMOND INCONYISWA NGAPHEZU KWE-CHESTNUT YASE-EUROPE UKUZE I-Diffuse Glioma KANYE NOKWELASHWA I-Procarbazine.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abasengozini yofuzo ye-Diffuse Glioma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma isipinashi?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Catechol, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis, i-PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints kanye ne-P53 Signaling nezinye. I-Butterbur Enkulu inconywa engcupheni ye-Diffuse Glioma lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Isipinashi yi-Curcumin, i-Quercetin, i-Apigenin, i-Lupeol, i-Catechol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Insulin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Isipinashi asinconywa uma ingozi ye-Diffuse Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zokusayina zaso.

IBUTTERBUR ENKULU YEZIBALO INCONYISWA NGAPHEZU KWESIPINSHI NGENGOZI YOMFUZA YE-ATRX.

Khetha Isithelo NANCE noma i-ACEROLA?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Catechol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, Hypoxia kanye ne-P53 Signaling nezinye. I-Nance inconywa engcupheni ye-Diffuse Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Acerola yi-Curcumin, i-Quercetin, i-Apigenin, i-Lupeol, i-Catechol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Insulin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Acerola ayinconywa uma ingozi ye-Diffuse Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-ACEROLA NGE-ATRX GENETIC RISK OF CANCER.

Khetha Nut BUTTERNUT noma BRAZIL NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Catechol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, Insulin Signaling kanye ne-P53 Signaling nezinye. I-Butternut inconywa engcupheni ye-Diffuse Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-Brazil Nut yi-Curcumin, i-Ellagic Acid, i-Lupeol, i-Catechol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Insulin Signaling, i-Angiogenesis kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Brazil Nut ayinconywa uma ingozi ye-Diffuse Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-BRAZIL NUT NGENGOZI YE-ATRX GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Diffuse Glioma. Iziguli ezisabalalisa i-Glioma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungekona?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Diffuse Glioma, ngayinye inofuzo oluhlukile lwesimila esinokwehluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Jute kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukene wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Diffuse Glioma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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