Ukudla kwe-Dermatofibrosarcoma Protuberans!

Isingeniso

Ukudla kwe-Dermatofibrosarcoma Protuberans kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Dermatofibrosarcoma protuberans (DFSP) iwuhlobo olungavamile lomdlavuza wesikhumba ovela ku-dermis. Ukuxilongwa okunembile kubalulekile, futhi uhlaka lwe-pathology lunikeza ulwazi olubalulekile mayelana nezici ezihlukile ze-DFSP. Ukubona izimpawu ze-DFSP, njengezilonda ezikhuphukayo ze-protuberant esikhumbeni, kubalulekile ukuze kutholakale ngokushesha kanye nokwelashwa ngokushesha. Ukubhala ngekhodi okufanelekile kwezokwelapha kusetshenziswa ikhodi efanele ye-ICD-10 kubalulekile ekubhalweni okunembile. I-Radiology idlala indima ebalulekile ekuhlolweni nasekuqaphelweni kwe-DFSP, isiza ekutholeni nasekuhlolweni kwesimila. Ukwelashwa kwe-DFSP ngokuvamile kubandakanya ukuhlinzwa okubanzi kwesimila, okungase kulandelwe izindlela zokwelapha ezengeziwe, ezifana nemisebe noma ukwelashwa okuhlosiwe. Izinga lokubikezela kanye nokusinda kwe-DFSP liyahlukahluka kuye ngezinto ezihlukahlukene, okuhlanganisa izinga nendawo yesimila. Ukuhlala unolwazi nokufuna usizo lwezempilo olufanele kubalulekile ukuze kuthuthukiswe imiphumela kubantu abane-DFSP. Ucwaningo oluqhubekayo kanye nokuthuthuka kwezinketho zokwelashwa kuyaqhubeka nokwenza ngcono ukuphathwa kwe-DFSP. Ngokuhlala bekhuthele futhi bethobela izinkombandlela zokwelashwa, abantu abane-DFSP bangathuthukisa amathuba abo okwelashwa okuphumelelayo kanye nokuphila isikhathi eside.

Ku-Dermatofibrosarcoma Protuberans kunendaba ukuthi imifino, izithelo, amantongomane, imbewu umuntu udlani?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abangaba sengcupheni yomdlavuza ukuthi - komdlavuza njenge-Dermatofibrosarcoma Protuberans ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-Dermatofibrosarcoma Protuberans?

Isibonelo, ingabe kunendaba ukuthi imifino ye-Brussels Sprouts idliwa kakhulu uma iqhathaniswa nesipinashi? Ingabe kuyawenza umehluko uma isithelo i-Malus (inkalankala i-Apple) sithandwa kune-Blackberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Walnut yaseJapane phezu kwe-Chestnut yase-Europe kanye nama-pulses afana ne-Black-eyed Pea phezu kwe-Lima Bean. Futhi uma lokho engikudlayo kunendaba - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Dermatofibrosarcoma Protuberans futhi ingabe impendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Dermatofibrosarcoma Protuberans!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Malus (i-crab Apple) iqukethe izithako ezisebenzayo i-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Lycopene, i-Daidzein. Futhi i-Blackberry iqukethe izithako ezisebenzayo i-Ellagic Acid, i-Quercetin, i-Myricetin, i-Linalool, i-Ferulic Acid kanye nezinye okungenzeka.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa yi-Dermatofibrosarcoma Protuberans - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo somsoco we-Dermatofibrosarcoma Protuberans.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Kwe-Dermatofibrosarcoma Protuberans?

Ukondleka komuntu siqu komdlavuza njenge-Dermatofibrosarcoma Protuberans kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Dermatofibrosarcoma Protuberans biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Dermatofibrosarcoma Protuberans

Yonke imidlavuza efana ne-Dermatofibrosarcoma Protuberans ingabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zesiginesha ze-Dermatofibrosarcoma Protuberans. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Growth Factor Signaling, i-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling, TGFB Signaling ziyingxenye yencazelo yesiginesha ye-Dermatofibrosarcoma Protuberans. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo kuma-Dermatofibrosarcoma Protuberans zidinga ukuqaphela izindlela zesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconywa i-Dermatofibrosarcoma Protuberans lapho uthatha ukwelashwa komdlavuza i-Imatinib, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-FGFR1, MED12, NF1, SUZ12 kanye ne-ATRX yizakhi zofuzo ezisezingeni eliphezulu ezibikwayo ze-Dermatofibrosarcoma Protuberans. I-FGFR1 ibikwa kuma-33.3% eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-MED12 ibikwa ku-33.3%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angu-20.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Dermatofibrosarcoma Protuberans biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelelwe izindlela ze-biochemical zesiginesha zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni zaziwa futhi lokho kufanele kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zeDermatofibrosarcoma Protuberans

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha imifino ye-BRUSSEL sprouts noma isipinashi?

Imifino ye-Brussel Sprouts iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Isoliquiritigenin, i-Lupeol, i-Daidzein, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Brussel Sprouts iyanconywa nge-Dermatofibrosarcoma Protuberans lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib. Lokhu kungenxa yokuthi i-Brussel Sprouts iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Imatinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Isipinashi yi-Quercetin, i-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling nezinye. Isipinashi asinconywa kuma-Dermatofibrosarcoma Protuberans lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib ngoba silungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

AMAPHUMELA E-BRUSSEL EZINJINI KUNCONYWA NGAPHEZU KWESIPINSHI KU-Dermatofibrosarcoma Protuberans KANYE NOKWELASHWA I-Imatinib.

Khetha isithelo BLACKBERRY noma i-MALUS (CRAB APPLE)?

I-Fruit Blackberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives njenge-Ellagic Acid, i-Quercetin, i-Myricetin, i-Linalool, i-Ferulic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, TGFB Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Blackberry inconywa i-Dermatofibrosarcoma Protuberans lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib. Lokhu kungenxa yokuthi i-Blackberry ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Imatinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Malus (i-crab Apple) yi-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Lycopene, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling nezinye. I-Malus (i-crab Apple) ayinconyelwe i-Dermatofibrosarcoma Protuberans uma ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO OMNYAMA SIYANCONYISWA NGAPHEZU KWE-MALUS (I-CRAB APPLE) NGE-Dermatofibrosarcoma Protuberans KANYE NOKWELASHWA I-Imatinib.

Khetha Nut JAPANESE WALNUT noma EUROPEAN CHESTNUT?

I-Walnut yaseJapane iqukethe izithako eziningi ezisebenzayo noma ama-bioactives njenge-Ellagic Acid, i-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, TGFB Signaling kanye ne-Growth Factor Signaling nezinye. I-Walnut yaseJapane iyanconywa nge-Dermatofibrosarcoma Protuberans lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib. Lokhu kungenxa yokuthi i-Walnut yaseJapane ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Imatinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yase-Europe yi-Ellagic Acid, i-Quercetin, i-Curcumin, i-Myricetin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling nezinye. I-Chestnut yase-Europe ayinconyelwe i-Dermatofibrosarcoma Protuberans uma ukwelashwa komdlavuza okuqhubekayo kuyi-Imatinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT YASE-JAPANESE INCONYISWA NGE-CHESTNUT YASE-EUROPE NGE-Dermatofibrosarcoma Protuberans KANYE NOKWELASHWA I-Imatinib.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo ye-Dermatofibrosarcoma Protuberans noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha Vegetable GIANT BUTTERBUR noma YAM?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis, i-TGFB Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Giant Butterbur inconywa ngengozi ye-Dermatofibrosarcoma Protuberans lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Yam yemifino yi-Curcumin, i-Apigenin, i-Myricetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Yam ayinconywa uma ingozi ye-Dermatofibrosarcoma Protuberans uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYISWA NGAPHEZU KWE-YAM NGENGOZI YOFUZO YE-ATRX YOMKHANZA.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, Suppressive Histone Methylation kanye ne-P53 Signaling nezinye. Okusajingijolo Okubomvu Kunconywa ngengozi ye-Dermatofibrosarcoma Protuberans lapho ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Red Raspberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Curcumin, i-Apigenin, i-Quercetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Pummelo ayinconywa uma ingozi ye-Dermatofibrosarcoma Protuberans uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-RASPBERRY EBOMVU ISITHELO INCONYISWA NGAPHEZU KWE-PUMMELO YE-ATRX GENETIC RISK OF CANCER.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, Suppressive Histone Methylation kanye ne-P53 Signaling nezinye. I-Hazelnut evamile inconywa ngengozi ye-Dermatofibrosarcoma Protuberans uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Curcumin, i-Apigenin, i-Ellagic Acid, i-Myricetin, i-Lycopene. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut ayinconywa uma ingozi ye-Dermatofibrosarcoma Protuberans uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT NGENGOZI YE-ATRX GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njenge-Dermatofibrosarcoma Protuberans. Iziguli ze-Dermatofibrosarcoma Protuberans kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungekona?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Dermatofibrosarcoma Protuberans, ngayinye ene-tumor genetics ehlukahlukene ngokuhlukahluka kwe-genomic kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Brussel Sprouts kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli ama-Dermatofibrosarcoma Protuberans?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-Daidzein yenza umsebenzi wokulwa ne-tumor ngokumelene namaseli omdlavuza wesinye ngokuvinjelwa kwendlela ye-FGFR3.
• I-Melatonin ne-vitamin D3 i-synergistically down-regulate i-Akt ne-MDM2 eholela ekuvimbeleni ukukhula okuncike ku-TGFβ-1 kwamangqamuzana omdlavuza webele.
• Ukuhlaziywa kwe-molecular docking ye-Cianidanol evela ku-Ginkgo biloba enethagethi yomdlavuza webele we-HER2+.
• I-Sulforaphane yenza i-apoptosis ku-rhabdomyosarcoma futhi ibuyisele ukuzwela kwe-TRAIL ku-subtype ye-alveolar enolaka eholela ekuqedweni kwesimila kumagundane.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• I-Paederia foetida idala umsebenzi wokulwa nomdlavuza ngokushintsha ama-enzyme okuguqula i-chromatin futhi iguqule ukubonakaliswa kwezakhi zofuzo ze-cytokine ezinokuvuvukala kumaseli omdlavuza wendlala yesinye.
• https://www.ncbi.nlm.nih.gov/books/NBK513305
• https://www.mayoclinic.org/diseases-conditions/dermatofibrosarcoma-protuberans/cdc-20352949