Ukudla kwe-Colorectal Adenocarcinoma!

Isingeniso

Ukudla kwe-Colorectal Adenocarcinoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukushintsha kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Colorectal adenocarcinoma wuhlobo lomdlavuza olusuka kumaseli axhume ikholoni noma i-rectum. Ukuqaphela izimpawu ze-colorectal adenocarcinoma kubalulekile ukuze kutholakale ngokushesha futhi kuhlanganisa izinguquko emikhubeni yamathumbu, igazi esitulweni, ubuhlungu besisu, nokuncipha kwesisindo okungahlosiwe. Ukufaka amakhodi okunembile kwe-colorectal adenocarcinoma kwenziwa lula uhlelo lwe-ICD-10. Izimpawu ze-pathology zinikeza ukuqonda kwezici zalo mdlavuza. I-Metastasis, noma ukusabalala kwethumba kwezinye izingxenye zomzimba, kuyisici esibalulekile ekunqumeni ukubikezela kanye nezinketho zokwelapha i-colorectal adenocarcinoma. Ukwelashwa ngokuvamile kuhilela inhlanganisela yokuhlinzwa, ukwelashwa ngamakhemikhali, nokwelashwa ngemisebe, kuye ngesiteji nezinga lomdlavuza. Ukuhlelwa kwe-colorectal adenocarcinoma kunikeza ulwazi olubalulekile mayelana nolaka lwesimila. Ukuqonda i-pathophysiology ye-colorectal adenocarcinoma kusiza ekuhlonzeni okungase kube okuhlosiwe kokwelashwa. Inqubo yesiteji ihlola izinga lomdlavuza, yenza izinqumo ezifanele zokwelashwa. Ukubhalwa okunembile kwe-colorectal adenocarcinoma kusetshenziswa uhlelo lwekhodi ye-ICD-10 CM kubalulekile kumarekhodi okunakekelwa kwezempilo. Izigaba ezithuthukile, njenge-stage 4 colorectal adenocarcinoma, zingadinga indlela yokwelapha enolaka. Kubalulekile ukuqonda umehluko phakathi kwe-colorectal carcinoma kanye ne-adenocarcinoma ukuze kutholakale ukuxilongwa nokuphathwa okunembile. Ukuqaphela izimbangela kanye nezici zobungozi ezihambisana ne-colorectal adenocarcinoma izinsiza ekuvimbeleni nasekungeneleleni kusenesikhathi. Ukuhlolwa okuvamile nokunakekelwa kwezokwelapha okufika ngesikhathi kudlala indima ebalulekile ekuthuthukiseni imiphumela yabantu abane-colorectal adenocarcinoma.

Ku-Colorectal Adenocarcinoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwe iziguli ezinomdlavuza kanye nabantu abangaba sengcupheni yomdlavuza ukuthi - komdlavuza ofana ne-Colorectal Adenocarcinoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-Colorectal Adenocarcinoma?

Isibonelo, ingabe kunendaba ukuthi iButterbur yemifino idliwa kakhulu uma iqhathaniswa neKhabishi Elimhlophe? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneRed Raspberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Butternut phezu kwe-European Chestnut kanye nama-pulses afana ne-Gram Bean phezu kwe-Yardlong Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Colorectal Adenocarcinoma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Colorectal Adenocarcinoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Pummelo iqukethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Futhi okusajingijolo Okubomvu kuqukethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Ellagic Acid, i-Daidzein, i-Isoliquiritigenin futhi mhlawumbe nabanye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Colorectal Adenocarcinoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni bese ungaziba ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo somsoco we-Colorectal Adenocarcinoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Kwe-Colorectal Adenocarcinoma?

Ukondleka komuntu siqu komdlavuza njenge-Colorectal Adenocarcinoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Colorectal Adenocarcinoma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Colorectal Adenocarcinoma

Yonke imidlavuza efana ne-Colorectal Adenocarcinoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zesiginesha ze-Colorectal Adenocarcinoma. Izindlela ze-Biochemical ezifana ne-Angiogenesis, PI3K-AKT-MTOR Signaling, MAPK Signaling, RAS-RAF Signaling ziyingxenye yencazelo yesiginesha ye-Colorectal Adenocarcinoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenza ngempumelelo kwe-Colorectal Adenocarcinoma kudinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconywa nge-Colorectal Adenocarcinoma lapho uthatha ukwelashwa komdlavuza i-Fluorouracil, futhi okunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TP53, i-APC, i-KRAS, i-TOP2A kanye ne-FBXW7 yizakhi zofuzo ezikleliswe phezulu ezibikwayo ze-Colorectal Adenocarcinoma. I-TP53 ibikwa ku-2.8 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-APC ibikwa ku-2.7%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esukela kwengu-4 kuye kwengama-95. Ama-54.9 % emininingwane yesiguli ahlonzwa njengabesilisa. I-Colorectal Adenocarcinoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical zesiginesha zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla kanye Nezithako ze-Colorectal Adenocarcinoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha I-Vegetable GIANT BUTTERBUR noma IKHABHISHI ELIMHLOPHE?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Myricetin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, NFKB Signaling, Epithelial to Mesenchymal Transition kanye neNetrin Signaling nezinye. I-Giant Butterbur iyanconywa nge-Colorectal Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil. Lokhu kungenxa yokuthi i-Giant Butterbur ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Fluorouracil.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Iklabishi Elimhlophe yi-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress kanye ne-Nucleotide metabolism nezinye. Iklabishi Elimhlophe alinconyelwe i-Colorectal Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBUTTERBUR OMKHULU WOKUMHLAZA INCONYISWA NGAPHEZU KWEKHABHISHI ELIMHLOPHE NGE-Colorectal Adenocarcinoma KANYE NOKWELASHWA I-Fluorouracil.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Curcumin, i-Ellagic Acid, i-Daidzein, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling, Epithelial to Mesenchymal Transition, PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. Okusajingijolo Okubomvu kunconyelwe i-Colorectal Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil. Lokhu kungenxa yokuthi i-Red Raspberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Fluorouracil.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress and DNA Repair nezinye. I-Pummelo ayinconyelwe i-Colorectal Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO ESIBOMVU I-RASPBERRY INCONYISWA NGAPHEZU KWE-PUMMELO YE-Colorectal Adenocarcinoma KANYE NOKWELASHWA I-Fluorouracil.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Myricetin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, i-NFKB Signaling, i-Epithelial to Mesenchymal Transition kanye ne-Netrin Signaling nezinye. I-Butternut inconywa nge-Colorectal Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Fluorouracil.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Quercetin, i-Curcumin, i-Ellagic Acid, i-Myricetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Nucleotide metabolism, Epithelial to Mesenchymal Transition kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut yase-Europe ayinconyelwe i-Colorectal Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Fluorouracil ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT YAseYurophu NGE-Colorectal Adenocarcinoma KANYE NOKWELASHWA I-Fluorouracil.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo ye-Colorectal Adenocarcinoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha Vegetable WILD LEEK noma SWEDE?

I-Vegetable Wild Leek iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints kanye ne-MYC Signaling nezinye. I-Wild Leek inconywa ngengozi ye-Colorectal Adenocarcinoma lapho ingozi yofuzo ehlotshaniswa nayo kuyi-APC. Lokhu kungenxa yokuthi i-Wild Leek inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yaseSweden yi-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Stem Cell Signaling, TGFB Signaling kanye ne-WNT Beta Catenin Signaling nezinye. I-Swede ayinconywa uma ingozi ye-Colorectal Adenocarcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC ngoba inyusa izindlela zayo zokusayina.

I-VEGETABLE WILD LEEK INCONYISWA NGAPHEZU KWE-SWEDE NGE-APC GENETIC RISK YOMKHANZA.

Khetha Isithelo NANCE noma SAPODILLA?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Myricetin, i-Daidzein, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Angiogenesis, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Nance inconywa engcupheni ye-Colorectal Adenocarcinoma lapho ubungozi bofuzo obuhlobene kuyi-APC. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni iSapodilla yiCurcumin, iLupeol, iMyricetin, iDaidzein, iFormononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress and Cell Cycle nezinye. I-Sapodilla ayinconywa uma ingozi ye-Colorectal Adenocarcinoma lapho ingozi yofuzo ehlotshaniswa nayo i-APC ngoba inyusa izindlela zokusayina zayo.

ISITHELO NANCE KUNCONYISWA NGAPHEZU KWE-SAPODILLA NGENGOZI YOMDLALO YE-APC.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Lupeol, i-Myricetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Angiogenesis, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Hazelnut evamile inconywa engcupheni ye-Colorectal Adenocarcinoma lapho ubungozi bofuzo obuhlobene kuyi-APC. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Chestnut yi-Curcumin, i-Ellagic Acid, i-Lupeol, i-Myricetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress kanye ne-TGFB Signaling nezinye. I-Chestnut ayinconywa uma ingozi ye-Colorectal Adenocarcinoma uma ingozi yofuzo ehlotshaniswa nayo kuyi-APC ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT YE-APC GENETIC RISK OF CANCER.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njenge-Colorectal Adenocarcinoma. Iziguli ze-Colorectal Adenocarcinoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Colorectal Adenocarcinoma, ngayinye enezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Giant Butterbur kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Colorectal Adenocarcinoma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Coad Caseccc 2015
• Ukuhlanganiswa kwe-R-spondin okuvamile kumdlavuza wekoloni.
• Ukulungiswa kwe-DNA kanye nemisebenzi ye-redox kanye nama-inhibitors e-apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): ukuhlaziya okuqhathanisayo kanye nobubanzi bayo kanye nemikhawulo ekuthuthukisweni kwezidakamizwa ezilwa nomdlavuza.
• I-citrus flavonoid naringenin ikhuthaza ukulungiswa kwe-DNA kumaseli omdlavuza wendlala yesinye.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• Inqubekelaphambili yocwaningo emiphumeleni yokulwa nomdlavuza kavithamini K2.
• Ukulawulwa okungekuhle kwe-transducer yesiginali kanye ne-activator ye-transcription-3 signaling cascade nge-lupeol ivimbela ukukhula futhi yenze i-apoptosis kumaseli e-hepatocellular carcinoma.